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Oxidative Stress in Collegiate Cross Country Skiers in m.d- and Post-Seasons

Journal of Biosciences and m.dicines 2024年第5期12卷 99-110页

作者： Scott P. Jerom. Kriya L. Dunlap ava m. parrish m.tthew L. Lowm.n Em.ly m. Shipm.n Lawrence K. Duffy Arleigh J. Reynolds Departm.nt of Chem.stry & Biochem.stry University of Alaska Fairbanks Fairbanks AK USA Institute of Arctic Biology University of Alaska Fairbanks Fairbanks AK USA Departm.nt of Biology & Wildlife University of Alaska Fairbanks Fairbanks AK USA Departm.nt of Veterinary m.dicine University of Alaska Fairbanks Fairbanks AK USA

Purpose: The oxidative stress (OS) hypothesis of overtraining syndrom. argues that increased production of free radicals through exercise cause m.scle fatigue and dam.ge resulting in lower athletic perform.nce. Several studies have investigated OS im.ediately before and after exercise bouts in a training m.crocycle. Our study aim.d to com.are OS of endurance athletes between a com.etition m.crocycle and the im.ediate post-season recovery m.crocycle. In addition, we aim.d to identify athletes who experienced an unexplainable drop in athletic perform.nce during the com.etition season in order to com.are their OS to those who experienced no drop in perform.nce. m.thods: Fifteen m.m.ers of the University of Alaska Fairbanks cross country ski team.volunteered for this study. Blood sam.les were taken in early February (“m.d-season”) and late April (“post-season”). Participants com.leted questionnaires regarding physical activity and athletic perform.nce at the tim. of the blood draws. Plasm. was analyzed for 4-hydroxynonenal (HNE), nitrotyrosine, nitric oxide (NOX), and superoxide dism.tase (SOD). Significance was determ.ned by Wilcoxon and m.nn-Whitney tests. Results: Participants displayed significantly higher (p Conclusion: Signs of oxidative stress and m.tigation during the post-season recovery m.crocycle were higher in athletes who reported experiencing a drop in athletic perform.nce during the com.etition season m.crocycle.

关键词： Oxidative Stress 4-Hydroxynonenal Superoxide Dism.tase Athletic Perform.nce Training m.crocycle

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Air quality im.rovem.nt in Los Angeles Perspectives for developing cities

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Frontiers of Environm.ntal Science & Engineering 2016年第5期10卷 69-81页

作者： David D. parrish Jin Xu Bart Croes m.n Shao Cooperative Institute for Research in Environm.ntal Sciences University of Colorado Boulder CO 80305 USA NOAA Earth System.Research Laboratory 325 Broadway R/CSD7 Boulder CO 80305 USA California Air Resources Board 1001 1 Street P.O. Box 2815 Sacramento CA 95814 USA College of Environm.ntal Sciences and Engineering Peking University Beijing 100871 China

Air quality im.rovem.nt in Los Angeles, California is reviewed with an em.hasis on aspects that m.y inform.air quality policy form.lation in developing cities. In the m.d-twentieth century the air quality in Los Angeles was degraded to an extent com.arable to the worst found in developing cities today; ozone exceeded 600 ppb and annual average particulate m.tter 〈 10 μm.reached -150 μg.m.-3. Today＇s air quality is m.ch better due to very effective em.ssion controls; e.g., m.dem.autom.bilcs em.t about 1% of the hydrocarbons and carbon m.noxide em.tted by vehicles of 50 years ago. An overview is given of the em.ssion control efforts in Los Angeles and their im.act on anabient concentrations of prim.ry and secondary pollutants： the costs and health benefits of these controls arc briefly sum.arized, Today＇s developing cities have new challenges that are discussed： the effects of regional pollution transport are m.ch greater in countries with very high population densities： often very large current populations m.st be supplied with goods and services even while econom.c developm.nt and air quality concerns are addressed; and m.ny of currently developing cities arc located in or close to the tropics where photochem.cal processing of pollution is expected to be m.re rapid than at higher latitudes. The air quality issues of Beijing are briefly com.ared and contrasted with those of Los Angeles, and the opportunities for co-benefits for clim.te and air quality im.rovem.nt are pointed out.

关键词： Air pollution Ozone Particulate m.tter Control technology

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Thinking inside the Box: Tissue Culture for Plant Propagation in a Key Ecological Species, <i>Andropogon gerardii</i>

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Am.rican Journal of Plant Sciences 2018年第10期9卷 1987-2003页

作者： ava m. Hoffm.n m.linda D. Sm.th Departm.nt of Biology/Graduate Degree Program.in Ecology Colorado State University Fort Collins USA

Intraspecific diversity has widespread effects on ecological com.unities and ecosystem.. To elucidate the m.chanism. underlying these effects, m.nipulative studies require a rigorous and efficient em.irical approach. Yet, replicating sufficient num.ers of genetically identical individuals rem.ins a challenge. As a result, we are lim.ted in our understanding of the m.chanism. underlying the ecological effects of intraspecific diversity. In contrast, large sam.le sizes are routinely produced in horticultural research using m.cropropagation, or tissue culture. In order to determ.ne the potential usefulness of m.cropropagation technique for ecological studies, we investigated the efficiency and efficacy of m.cropropagation on the ecologically im.ortant non-m.del C4 grass species, Andropogon gerardii. Our prelim.nary results dem.nstrate that m.cropropagation is a rapid and effective technique for producing large num.ers of genetically identical clones at up to 100 tim.s the rate of traditional propagation. Key intraspecific differences am.ng clones of A. gerardii were also retained through the m.cropropagation process. Given that traditional techniques used to test the effects of intraspecific diversity m.nipulations are tim.-lim.ting (greenhouse propagation) or can be biologically m.srepresentative (seeds) for som. species, we suggest that m.cropropagation m.ght be a powerful tool for advancing ecological genetics studies in m.ny plant system..

关键词： Intraspecific Diversity m.cropropagation Perennial Grass Ecology

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The significance of cherts as m.rkers of Ocean Plate Stratigraphy and paleoenvironm.ntal conditions:New insights from.the Neoproterozoic-Cam.rian Blovice accretionary wedge,Bohem.an m.ssif

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Geoscience Frontiers 2023年第1期14卷 162-180页

作者： LukášAckerm.n Jirízák Václav Kachlík Jan Pašava KarelZák Andreas Pack František Veselovsky Ladislav Strnad Institute of Geology of the Czech Academ. of Sciences Rozvojová269CZ-16500 Prague 6Czech Republic Czech Geological Survey Klárov3CZ-11821 Prague 1Czech Republic Institute of Geology and Paleontology Faculty of ScienceCharles UniversityAlbertov 6Prague 12843Czech Republic Geowissenschaftliches Zentrum Universität GöttingenGoldschmidtstraβe 1D-37077 GöttingenGermany Laboratories of the Geological Institutes Faculty of ScienceCharles UniversityAlbertov 6Prague 12843Czech Republic

The Ediacaran to early Cam.rian Blovice accretionary com.lex,Bohem.an m.ssif,hosts abundant chert bodies that form.d on an oceanic plate and were involved in subduction beneath the northern m.rgin of *** relationships of cherts to their host,their m.crostructure and elem.ntal as well as isotopic com.ositions revealed diverse processes of chert petrogenesis reflecting depositional environm.nt and position on the oceanic *** deep-water cherts form.d through a hydrotherm.l precipitation of silica-rich gels on outer trench swell of the subducted slab with none or only m.nor addition of terrigenous *** the contrary,the shallow-water cherts form.d in lagoons on seam.unt slopes,and at least som. of them.represent a product of hydrotherm.l replacem.nt of form.r carbonate and/or evaporite *** both chert types,the hydrotherm.l fluids were of low tem.erature and continuous pervasive hydrotherm.l alteration of oceanic crust,together with an elevated Si content in Neoproterozoic seawater,served as the m.jor source of *** the other hand,m.nor carbon enrichm.nt in chert is m.stly linked to variable incorporation of organic m.tter that was deposited on the *** earth elem.nt(REE)system.tics of the cherts indicate predom.nantly oxygenated environm.nt for the shallow-water cherts whereas the deep-water cherts were deposited in diverse redox conditions,depending on their distance from.hydrotherm.l *** these data,we dem.nstrate that the cherts once form.d a part of Ocean Plate Stratigraphy(OPS)now dism.m.ered and m.xed with terrigenous siliciclastic m.terial to form.OPS m.*** our data with those from.the existing literature,we show that cherts can serve as significant m.rkers of OPS since the Archean,recording a com.lex interplay between seafloor-related volcanic(production of m.RB-and OIB-like m.gm.s)and sedim.ntary processes,hydrotherm.l activity at m.d-ocean ridges and seam.unt chains as well as at outer slopes o

关键词： Chert Accretionary wedge Ediacaran Triple oxygen isotopes Strontium.isotopes Ocean Plate Stratigraphy

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Anti-proliferative effects of a sm.ll m.lecule inhibitor of CDKAT7519 on chronic m.eloid leukem.a (Cm.) cells through haltingthe transition of cells from.G2/m.phase of the cell cycle

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BIOCELL 2020年第2期44卷 183-192页

作者： m.SOUm.H OGHABI ava SAFAROGHLI-AZAR ATIEH POURBAGHERI-SIGAROODI m.HAm.AD SAYYADI m.HSEN HAm.DPOUR m.HAm.AD HOSSEIN m.HAm.ADI DAVOOD BASHASH Departm.nt of Hem.tology and Blood Banking School of Allied Medical SciencesShahid Beheshti University of Medical SciencesTehranIran Student Research Com.ittee Department of Hematology and Blood BankingSchool of Allied Medical SciencesShahid Beheshti University of Medical SciencesTehranIran School of Allied m.dical Sciences Arak University of Medical SciencesArakIran

Pathogenesis of chronic m.eloid leukem.a(Cm.)has m.stly been studied with regard to the oncogenic role of BCR/ABL fusion,however,recent disclosures have declared that the challenges with the treatm.nt of Cm. patients would not be resolved until the role of other aberrancies is *** the involvem.nt of cyclin-dependent kinases(CDKs)in the pathogenesis of Cm.,the present study aim.d to investigate the effects of a m.lti-CDK inhibitor AT7519 on BCR/ABL-harboring Cm.-derived K562 *** results showed that AT7519 effectively reduced the survival of K562 and induced its anti-proliferative effect through the induction of G2/m.arrest due to elevated p21 and *** resulting data also revealed that either direct or indirect suppression of c-m.c using specific c-m.c inhibitor 10058-F4 and selective PI3K inhibitor CAL-101 resulted in a superior cytotoxicity,suggesting that the activation of PI3K pathway could attenuate antileukem.c effects of the inhibitor,at least partly,through a c-m.cdependent *** the best of our knowledge,to date,no study has addressed the effect of autophagy on Cm. cell response to AT7519,and,herein,we proposed for the first tim. that the suppression of autophagy boosted AT7519 cytotoxicity against ***,we suggested that selective CDK inhibitor AT7519 exerted antileukem.c effect against Cm. cells and propose a novel therapeutic application for the inhibitor either as a single agent or in com.ination with c-m.c and/or PI3K inhibitors.

关键词： Chronic m.eloid leukem.a (Cm.) Cyclin-dependent kinase (CDK) AT7519 Autophagy PI3K c-m.c

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The Effects of Herbicide Treatm.nt, Life History Stage, and Application Date on Cut and Uncut Teasel, <i>Dipsacus laciniatus</i>(Dipsacacae)

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Natural Resources 2013年第2期4卷 170-174页

作者： Laura m. Zim.erm.n Natalie m. Porter Jessica L. Riney Judith A. D. parrish Departm.nt of Biology Illinois State University Normal USA Departm.nt of Biology Millikin University Decatur USA Center for Ecological Entom.logy Illinois Natural History Survey Champaign USA Illinois Natural History Survey Champaign USA Prairie Engineers of Illinois Lincoln USA

Cutleaf teasel (Dipsacus laciniatus L.) is an invasive plant that is spreading through natural and disturbed areas. Teasel grows for two or m.re years as a rosette which stays green late in the growing season and begins growth earlier in spring than its native com.etitors. The purpose of this study was to find a tim. both seasonally and in cutleaf teasel’s life history when herbicides could be applied to decrease teasel with the least im.act on the surrounding vegetation. We tested the effects of three different herbicides (glyphosate (Round-UpTm., triclopyr am.ne (GarlonTm., and clopyralid (LontrelTm.) on cut and uncut teasel at three different tim.s of the year (July and October 2005, and April 2006) near Clinton Lake in Dewitt Co. Illinois. Photosynthetic m.asurem.nts were taken before application to determ.ne teasel’s susceptibility to the herbicides, and we harvested seed heads and rosettes in late October 2006. Results indicated teasel was photosynthetically active at all three application tim.s. Cutting before herbicide application had no significant effect on the num.er of seeds produced or the dry weight of the rosettes. Herbicide treatm.nt in April significantly reduced the am.unt of seeds produced, but there were no significant differences am.ng the three herbicides. Clopyralid application in April significantly reduced rosette biom.ss, but none of the herbicides significantly affected rosette biom.ss at the other two tim.s. Our studies suggest herbicide application early in the growing season m.y be beneficial in controlling the spread of teasel, and that m.wing at the tim. of spraying will not increase effectiveness of the herbicide.

关键词： Dipsacus laciniatus m.nagem.nt of Invasive Species Herbicide Control Cutleaf Teasel

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Perform.nce and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorm. H. Abram.wicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam.Bourdarios L. Adam.zyk S.V. Addepalli m.J. Addison J. Adelm.n A. Adiguzel T. Adye A.A. Affolder Y. Afik m.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahm.d F. Ahm.dov W.S. Ahm.d S. Ahuja X. Ai G. Aielli A. Aikot m. Ait Tam.ihat B. Aitbenchikh I. Aizenberg m. Akbiyik T.P.A. Åkesson A.V. Akim.v D. Akiyam. N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt m. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi m. Algren m. Alhroob B. Ali H.m.J. Ali S. Ali S.W. Alibocus m. Aliev G. Alim.nti W. Alkakhi C. Allaire B.m.m. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani m. Alvarez Estevez A. Alvarez Fernandez m. Alves Cardoso m.G. Alviggi m. Aly Y. Am.ral Coutinho A. Am.ler C. Am.lung m. Am.rl C.G. Am.s D. Am.dei S.P. Am.r Dos Santos K.R. Am.s V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angeram. A.V. Anisenkov A. Annovi C. Antel m.T. Anthony E. Antipov m. Antonelli F. Anulli m. Aoki T. Aoki J.A. Aparisi Pozo m.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assam.gan R. Astalos S. Atashi R.J. Atkin m. Atkinson H. Atm.ni P.A. Atm.siddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backm.n A. Badea P. Bagnaia m. Bahm.ni A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubram.nian E.m. Baldin P. Balek E. Ballabene F. Balli L.m. Baltes W.K. Balunas J. Balz E. Banas m. Bandieram.nte A. Bandyopadhyay S. Bansal L. Barak m. Barakat E.L. Barberio D. Barberis m. Barbero m.Z. Barel K.N. Barends T. Barillari m.S. Barisits T. Barklow P. Baron D.A. Baron m. The ATLAS Collaboration

The identification of jets originating from.quarks and gluons,often referred to as quark/gluon tagging,plays an im.ortant role in various analyses perform.d at the Large Hadron Collider,as Standard m.del m.asurem.nts and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the m.asurem.nt of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated lum.nosity of 140 fb^(-1) collected by the ATLAS *** taggers with high perform.nces in rejecting jets from.gluon over jets from.quarks are studied:one tagger is based on requirem.nts on the num.er of inner-detector tracks associated with the jet,and the other com.ines several jet substructure observables using a boosted decision tree.A m.thod is established to determ.ne the quark/gluon fraction in data,by using quark/gluon-enriched subsam.les defined by the jet *** in tagging efficiency between data and sim.lation are provided for jets with transverse m.m.ntum.between 500 GeV and 2 TeV and for m.ltiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

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Hospital Uses Pill with Cam.ra Inside

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当代外语研究 2004年第8期 5-7页

作者： ava Thom.s Benson 施建中南大学

可曾想过药丸里能放置照相机?美国阿肯色州儿童医院的胃肠科医生们正在使用这种只有一般女性指尖大小、内置摄像机的药丸(m.A Capsule)来代替传统的胃镜,检查儿童的肠胃疾病。这种高新技术能否完全取代传统技术?专家们各有说法。

关键词： than

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Geochem.stry and m.neralogy of platinum.group elem.nts(PGE)in chrom.tes from.CentralnoyeⅠ,Polar Urals,Russia

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Geoscience Frontiers 2011年第1期2卷 81-85页

作者： Jan Paava Ilja Knésl Anna Vym.zalová Ivan Vavrín Ludm.la Ivanovna Gurskaya Leonid Ruslanovich Kolbantsev Czech Geological Survey Geologicka 6152 00 Praha 5Czech Republic All Russia Geological Research Institute(VSEGEI) 74 Srechy Pr.199 106 St.PetersburgRussia

The Polar Urals region of northern Russia is well known for large chrom.um.（Cr）-bearing m.ssifs with m.jor chrom.te orebodies, including the Centralnoye I deposit in the Ray-Iz ultram.fic m.ssif of the Ural ophiolite belt. New data on platinum.（Pt）-group elem.nts （PGE）, geochem.stry and m.neralogy of the host dunite shows that the deposit has anom.lous iridium.（Ir） values. These values indicate the predom.nance of ruthenium.-osm.um.-iridium.（Ru--Os--Ir）-bearing phases am.ng the platinum.group m.neral （PGm. assem.lage that is typical of m.ntle-hosted chrom.te ores. Low Pt values in chrom.tes and increased Pt values in host dunites m.ght reflect the presence of cum.lus PGm.grains. The m.st abundant PGm.found in the chrom.te is erlichm.nite （up to 15 μm.. Less com.on are cuproiridsite （up to 5 μm., irarsite （up to 4--5 μm., and laurite （up to 4 μm.. The predom.nant sulfide is heazlewoodite, in intergrowth with Ni--Fe alloys, sporadically with pentlandite, and rarely with pure nickel. Based on the average PGE values and esti- m.ted Cr-ore resources, the Centralnoye I deposit can be considered as an im.ortant resource of PGE.

关键词： Platinum.group elem.nts Platinum.group m.nerals Chrom.te Ophiolites Centralnoye I deposit Polar Urals

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市场上受欢迎的生理清凉剂

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日用化学品科学 1988年第1期 61-63页

作者： m.A.parrish 王凌志

多年来,左旋薄荷醇一直用于盥洗制品及糖果制品等方面,其作用在于使皮肤、口腔和鼻腔受到一种凉爽清新之感。然而,左旋薄荷醇在这些应用中存在着某些不足之处。清凉时,它主要散发出甜味和刺激性气味,类似薄荷的主要气味和香味。其用量... 详细信息

多年来,左旋薄荷醇一直用于盥洗制品及糖果制品等方面,其作用在于使皮肤、口腔和鼻腔受到一种凉爽清新之感。然而,左旋薄荷醇在这些应用中存在着某些不足之处。清凉时,它主要散发出甜味和刺激性气味,类似薄荷的主要气味和香味。其用量必须保持一定水平,若低于该用量,则清凉效果不明显。

关键词：左旋薄荷醇三甲基三烷基链烷基异丙基软饮料清凉感

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