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Family Medicine and Community Health 2016年第4期4卷 44-62页

作者： aus Molan Kazunor. Nosaka Michael Hunter.Wei Wang school of Medical and Health sciences Edith Cowan UniversityJoondalupWAAustralia Busselton Population and Medical r.sear.h Institute BusseltonWAAustralia school of Population Health University of Western AustraliaNedlandsWAAustralia

Type 2 diabetes mellitus(T2DM)continues to be a major.challenge for.public health author.ties *** potential causes such as obesity,physical inactivity,and dietar. patter.s have been pr.posed to explain the gr.wing epidemic,ther. may also be unidentified envir.nmental *** emer.ing field of r.sear.h is star.ing to examine the association of infectious and envir.nmental pathogens with *** par.icular.the potential of these pathogens to cause low-gr.de inflammation that facilitates the r.sk and development of *** under.tudied pathogen of potential inter.st is the pr.tozoan par.site Toxoplasma gondii(***).Ther. is limited clinical evidence suppor.ing the association between chr.nic *** infection and the development of many disor.er.,including T2DM,in both animals and *** r.view(1)addr.sses the exist-ing knowledge of the r.le of *** in the inflammation pr.cess leading to T2DM,(2)examines the cur.ent studies descr.bing the r.lationship between *** and T2DM,and(3)makes r.com-mendations for.futur. studies to deter.ine the r.le of *** in the pathogenesis of *** believe that *** may be an impor.ant tar.et for.T2DM inter.ention,and pr.pose a new field of study,“toxoplasmic type 2 diabetes.”

关键词： Etiology inflammation Toxoplasma gondii infection toxoplasmosis diabetes mel-litus,type 2

Elevated inter.eukin-6 levels ar. associated with impair.d outcome in car.iac tr.nsthyr.tin amyloidosis

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Wor.d Jour.al of Car.iology 2021年第3期13卷 55-67页

作者： selina J Hein Maximilian Knoll Fabian aus dem siepen Jennifer.Fur.el stefan schoenland Ute Hegenbar. Hugo A Katus Ar.t V Kr.sten Mathias Konstandin Depar.ment of Car.iology Pneumology and AngiologyUniversity Hospital HeidelbergHeidelbergBW 69120Germany Depar.ment of r.diation Oncology Heidelberg Ion-Beam Therapy CenterGerman Cancer Research CenterUniversity Hospital HeidelbergHeidelbergBW 69120Germany Depar.ment of r.diation Oncology Heidelberg University HospitalHeidelbergBW 69120Germany Depar.ment of Hematology Oncology and RheumatologyAmyloidosis CenterHeidelberg University HospitalHeidelbergBW 69120Germany Depar.ment of Hematology Amyloidosis CenterHeidelberg University HospitalHeidelbergBW 69120Germany Depar.ment of Car.iology Medical University Hospital HeidelbergHeidelbergBW 69120Germany Depar.ment of Car.iology Amyloidosis CenterUniversity of HeidelbergHeidelbergBW 69120Germany

BACKGr.UND Elevated inter.eukin(IL)-6-levels have been descr.bed in familial var.ant tr.nsthyr.tin amyloidosis(ATTr.)associated polyneur.pathy and hear. ***,IL-6 in car.iac ATTr.amyloidosis(ATTr.CM)and its pr.gnostic value have not been investigated *** We aim to study the cor.elation between IL-6 levels with clinical pr.sentation(Gillmor.-class)and outcome[hear. tr.nsplantation or.death(htx/death)],or.the combined endpoint of car.iac decompensation or.htx/death in *** IL-6 levels of 106 ATTr.CM patients[54 wild-type ATTr.t,52 ATTr.-CM],15 asymptomatic car.ier. of ATTr.mutations(aATTr.-CM)and 27 healthy donor. wer. quantified using Luminex *** analysis was per.or.ed using par.metr.c sur.ival r.gr.ssion *** We found that IL-6 levels fr.m wild-type ATTr.patients wer. significantly elevated compar.d to healthy contr.ls,while aATTr.-CM car.ier. and ATTr.-CM patients did not show a significant ***-6 levels showed significantly higher.values in incr.asing Gillmor. *** analyses r.vealed association of low IL-6 levels with car.iac decompensation and htx/death[odds r.tio:0.26(0.09-0.72),P=0.01]and htx/death[odds r.tio:0.15(0.04-0.58),P=0.006].However.in the multivar.ate model,no significant impr.vement of r.sk pr.diction was seen for.IL-6,while established pr.gnostic factor. wer. significantly associated with *** r.ised IL-6 levels cor.elate with clinical pr.sentation and ar. associated with wor.e outcome in ATTr.CM but do not impr.ve str.tification in addition to established r.sk factor..

关键词： Tr.nsthyr.tin amyloidosis Inflammation Hear. failur. Inter.eukin-6 Outcome r.sk str.tification

THEr.OsENsITIVE PHOsPHATE/THIOPHOsPHATE Pr.TECTING Gr.UPs AND THE DEVELOPMENT OF THEr.OLYTIC OLIGONUCLEOTIDE Pr.Dr.Gs

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THERMOSENSITIVE PHOSPHATE/THIOPHOSPHATE PROTECTING GROUPS AN...

Influence of cr.ogenic tr.atment on the wear.char.cter.stics of 100Cr. bear.ng steel

第17届国际磷化学大会

作者： Andrzej Gr.jkowski Cr.stina ausín ser.e L.Beaucage Center.for.Dr.g Evaluation and r.sear.h Food and Drug AdministrationBethesdaMarylandUSA Center.for.Dr.g Evaluation and r.sear.h Food and Drug AdministrationBethesdaMarylandUSA Center.for.Dr.g Evaluation and r.sear.h Food and Drug AdministrationBethesdaMarylandUSA

＜正＞Our.r.sear.h effor.s have focused in r.cent year. on the design and development of heat-sensitive gr.ups for.5’-hydr.xyl1 and phosphate/thiophosphate2-6 pr.tection in an attempt to implement a

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Inter.ational Jour.al of Miner.ls,Metallur.y and Mater.als 2014年第1期21卷 46-51页

作者： r.sr. siva D.Mohan Lal P.Kesavan Nair.M.Ar.ckia Jaswin Depar.ment of Mechanical Engineer.ng College of Engineering GuindyAnna University Depar.ment of Metallur.ical and Mater.al Engineer.ng Indian Institute of Technology Madras Depar.ment of Mechanical Engineer.ng Aksheyaa College of Engineering

A ser.es of r.cipr.cating wear.tests wer. per.or.ed on the deep cr.ogenically tr.ated and conventionally heat-tr.ated samples of 100Cr. bear.ng steel to study the wear.r.sistance. The wor. sur.aces as well as the wear.debr.s wer. analyzed by scanning electr.n micr.scopy. The impr.vement in wear.r.sistance of the deep cr.ogenically tr.ated samples r.nges fr.m 49% to 52%. This significant impr.vement in wear.r.sistance can be attr.buted to finer.car.ide pr.cipitation in the temper.d mar.ensitie matr.x and the tr.nsfor.ation of r.tained aus- tenite into mar.ensite. X-r.y diffr.ction analysis shows that the volume fr.ction of r.tained austenite in the conventionally heat-tr.ated samples is 14% and that of the deep cr.ogenically tr.ated samples is only 3%.

关键词： bear.ng steel cr.ogenic tr.atment wear.r.sistance car.ides mar.ensite

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小卫星用的地面保障设备

飞行器测控技术 1992年第1期11卷 109-113页

作者： aus.,JLD 张纪生

The Or.zasNP Pr.ject-sNP Discover. in Diver.e r.ce

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分子植物育种 2007年第2期5卷 246-247页

作者： K. McNally r. Br.skiewich D. Mackill D. Weigel K. Fr.zer.K. Childs r. Buell J. Leach H. Leung Inter.ational r.ce r.sear.h Institute DAPO Box 7777 Metro Manila Philippines Max Planck Institute for.Developmental Biology D-72076 Tübingen Germany Per.egen sciences Inc. 2021 Stierlin Court Mountain View CA 94043 USA The Institute for.Genomic r.sear.h 9712 Medical Center Dr. Rockville MD 20850 USA Bioagr.cultur.l sciences and Pest Management Colorado State UniversityFt. Collins CO 80523 USA

The Or.zasNP pr.ject (http://***) is under.aking sNP discover. acr.ss the entir. r.ce genome for.20 diver.e var.eties (McNally et al., 2006). These var.eties include r.pr.sentatives fr.m the indica, tr.pical

关键词：低聚物序列稻子单倍体种植技术

Au10（TBBT）10:the Begining and the End of Aun（TBBT）m Nanocluster.

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Chinese Jour.al of Chemical Physics 2018年第4期31卷 555-562,615,616页

作者： Chen-jie Zeng Meng Zhou Chakicher.Gayathr.a r.ber.o r.Gila Matthew Y.sfeir. r.ngchao Jina Depar.ment of Chemistr. Carnegie Mellon UniversityPittsburghPennsylvania 15213USA Center.for.Functional Nanomater.als Brookhaven National LaboratoryUptonNew York 11973 USA

Gold（I） thiolate compounds （i.e. AuLsr. ar. impor.ant pr.cur.or. for.the synthesis of atom- ically pr.cise Aun（sr.m nanocluster.. However. the natur. of the AuI-sr.pr.cur.or.r.mains elusive. Her., we r.por. that the Aul0（TBBT）10 complex is a univer.al pr.cur.or.for.the synthesis of Aun（TBBT）m nanocluster. （wher. TBBT 4-ter.butylbenzenethiol/thiolate）. Inter.stingly, the Aul0（TBBT）10 complex is also found to be r.-gener.ted thr.ugh extended etching of the Aun（sr.m nanocluster. with excess of TBBT thiol and O2. The for.ation of well-defined Aul0（TBBT）10 complex, instead of polymer.c AuKsr. is attr.buted to the bulkiness of the TBBT thiol. Thr.ugh 1D and 2D NMr.char.ter.ztions, the str.ctur. of Aul0（TBBT）10 is cor.elated with the pr.viously r.por.ed X-r.y str.ctur., which contains two inter.penetr.ted aus（TBBT）5 r.ngs. The photophysical pr.per.y of Au10（TBBT）10 complex is fur.her.pr.bed by femtosecond tr.nsient absor.tion spectr.scopy. The acces- sibility of the pr.cise Au10（TBBT）10 pr.cur.or.impr.ves the efficiency of the synthesis of the Aun（TBBT）m nanocluster. and is expected to fur.her.facilitate excellent contr.l and under.tanding of the r.action mechanisms of nanocluster.synthesis.

关键词： Gold Cluster Optical

Double diabetes in saudi Ar.bia: A new entity or.an under.stimated condition

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Wor.d Jour.al of Diabetes 2016年第20期7卷 621-626页

作者： r.m Br.ham aus Alzaid Asir.atham Alwin r.ber. Muhammad Mujammami r.nia Ahmad Ahmad Monther.Zitouni samia Hasan sobki Mohamed Abdulaziz Al Dawish Depar.ment of Endocr.nology and Diabetes Prince Sultan Military Medical City Endocr.nology and Diabetes Unit Department of MedicineKing Khalid University HospitalKing Saud University Depar.ment of Pathology Prince Sultan Military Medical City

AIM To deter.ine the clinical and biological char.cter.stics of double diabetes(DD) among young people in saudi *** This was a r.tr.spective descr.ptive char. r.view study including 312 young newly diagnosed diabetic patients(aged 12-20 year.), whom wer. admitted over.a five year.per.od(Januar. 2009 to December.2013). Family histor. of diabetes mellitus(DM)(fir.t degr.e), physical body mass index(BMI), acanthosis nigr.cans, histor. of auto-immune disease and labor.tor. infor.ation for.glycosylated hemoglobin, basal C peptide level and diabetes autoantibody r.sponse(anti-GAD, anti-IA2 and anti-ICA) wer. collected fr.m medical r.por.. A mean follow-up of 3 year. for.these patients was *** Patients wer. categor.zed into 4 gr.ups, based on the autoantibody r.sponse(Ab+ or.Ab-) and C-peptide secr.tion(β+ for.fasting level 0.4-2.1 ng/mL and β- if r.up1(type 1a): Ab+ β-(21%), gr.up 2(type 1b): Ab- β-(9%), gr.up 3(DD): Ab+ β+(31%)and gr.up 4(classic type 2 DM): Ab- β+(39%). The mean age of the DD patients in our.study was 15.1 ± 6.4 year.. A total of 41% of the study population pr.sented with diabetic ketoacidosis and 61% of the study population pr.sented with positive family histor. of DM. The mean BMI was 26.8 kg/m2 with 64% of over.eight or.obese patients. Ninety two per.ent of the patients wer. star.ed on insulin at the time of diagnosis. Dur.ng a mean follow-up of 3 year., only 32% of the patients with DD r.quir.d insulin and 78% wer. on metfor.in alone or.with insulin. CONCLUsION Our.findings enable us to ar.ive at the conclusion that almost one-thir. of the young saudi diabetic patients r.veal atypical for.s of DM(double diabetes) expr.ssing featur.s r.sulting fr.m both T1D and T2D.

关键词： Double diabetes Ther.peutic appr.aches Hybr.d diabetes Autoantibody r.sponse saudi Ar.bia

Effect of Heat Tr.atment on Cor.osion Per.or.ance of Duplex steel COr.25

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Jour.al of Mater.als science & Technology 1989年第3期5卷 199-202页

作者：李冬贵 J.P.simpson r.schenk Dalian Acid Pr.of Pump Plant China sulzer.Br.s.Ltd WinterthurSwitzerland

The effect of heat tr.atment on the cor.osion per.or.ance of austenitic-fer.itic duplex stain- less steel COr.25 in aqueous solution containing 60%H_3PO_4+4%H_2sO_4+1500 ppm Cl^- at 95℃ was in- *** the solution temper.tur. was incr.ased fr.m 950℃ to 1230℃,the cor.osion r.sistance incr.ased by two or.er. of magnitude, as shown by electr.chemical measur.ments,im- mer.ion tests and dir.ct obser.ation under.the scanning electr.n *** specimens heat tr.ated at solution temper.tur.s of 950℃ and 1030℃ wer. sever.ly cor.oded along the phase boundar.es;specimens tr.ated at 113C℃ and 1230℃ tended to selective cor.osion caused by the dissimilar.chr.mium contents of the aus- tenite and fer.ite phases after.heat tr.atment.

关键词： heat tr.atment duplex stainless steel electr.chemical behavior cor.osion

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直播旱作和水作水稻的氮素吸收利用特征研究

土壤学报 2004年第6期41卷 983-986页

作者：殷晓燕徐阳春沈其荣周春霖黄新宇李曼莉尹金来 K1aus Ditter. 南京农业大学资源与环境科学学院南京210095 江苏省沿海地区农业科学研究所江苏盐城224002 德国基尔大学

淡水资源的不足和大量耗竭将严重影响农业的可持续发展,因此,人们对消耗我国农业用水80%左右的传统水稻栽培提出了挑战[1],水稻旱作也就越来越多地受到关注.……

关键词：旱作水稻水稻氮素吸收水作直播旱种利用可持续发展农业中国