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Friction 2024年第8期12卷 1785-1800页

作者： Javier BLANCO-rod.Íguez Jacobo PORTEIRO JoséA.LÓPEZ-CAMPOS MartíCORTADA-GARCÍA Silvia FERNÁNDEZ-CASTEJÓN CINTECX Universidade de VigoLagoas-Marcosende s/nVigo 36310Spain Repsol SA MadridSpain

Durability and reliability have been studied for decades through intensive trial-error ***,there are numerous fields of application where the costs associated with this approach are not *** lubricated machines with severe dynamic loads,such as high-power-density engines,simulation tools offer clear advantages over intensive *** and multiple scenarios can be cost-effectively simulated to assess different lubricants and engine *** work presented here details the study of wear based on a validated elastohydrod.namic(EHD)simulation model of the connecting rod.journal *** model accounts for elastic deformation through a connecting rod.finite element model(FEM).In addition,multiple lubricant rheological and tribological dependences,determined by specific experimental tests,are applied in the model through their interaction with the simulation ***,a novel wear algorithm is proposed to predict wear depth over time evolution along a proposed wear cycle based on the typical working ranges of high-performance engines.A final assessment is presented to compare 4 different ultralow-viscosity lubricants in their protective performance under severe *** results show the evolution of the wear load and wear depth over the wear *** evaluation is key to describing a lubricant selection procedure for high-power-density engines.

关键词： wear modelling finite element modelling mixed lubrication elastohydrod.namic(EHD) internal combustion engines bearings

Circularly polarized luminescence of enantiopure carboline-based europium cryptates under visible light excitation

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Journal of Rare Earths 2020年第5期38卷 564-570页

作者： Carolin Dee Francesco Zinna Elisabeth Kreidt Lorenzo Arrico aurora rod.iguez-rod.iguez Carlos Platas-Iglesias Lorenzo Di Bari Michael Seitz University of Tübingen Institute of Inorganic ChemistryAuf der Morgenstelle 1872076TubingenGermany Dipartimento di Chimica e Chimica Industriale Universita di PisaVia Moruzzi 1356124PisaItaly Centro de Investigacions Cientificas Avanzadas(CICA)and Departamento de Quimica Universidade da CorunaCampus da Zapateira-Rua da Fraga 1015008A CorunaSpain

The enantiomers of carboline-based cryptates were successfully resolved by chiral *** complexes show high configurational stability under harsh conditions and their absolute configuration was determined by comparing theoretical and expe rimental electronic circular dichroism *** e nantiopure cryptates exhibit strong circularly polarized luminescence with a maximum dissymmetry factor glum=0.25 for the f-f transition 5 D0→7 F1(λ=594 nm)under visible light excitation atλgx=400 nm.

关键词： Molecular lanthanoid complexes Lanthanoid luminescence Chirality Circularly polarized luminescence(CPL) Carboline Cryptates

GOECP/SEOR clinical recommendations for lung cancer radiotherapy during the COVID-19 pandemic

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World Journal of Clinical Oncology 2020年第8期11卷 510-527页

作者： Felipe Couñago Arturo Navarro-Martin Javier Luna Nuria rod.íguez de Dios aurora rod.íguez Francesc Casas Rafael García Antonio Gómez-Caamaño Jorge Contreras Javier Serrano Department of Radiation Oncology Hospital Universitario Quirónsalud MadridPozuelo de AlarcónMadrid 28223Spain Clinical Department Hospital La LuzMadridFaculty of BiomedicineUniversidad EuropeaMadrid 28223Spain Department of Radiation Oncology Institut Catalád’OncologiaL’Hospitalet de LlobregatBarcelona 08908Spain Department of Radiation Oncology Hospital Fundación Jiménez DíazMadrid 28040Spain Department of Radiation Oncology Hospital del MarBarcelona 08003Spain Department of Radiation Oncology Hospital Ruber InternacionalMadrid 28034Spain Department of Radiation Oncology Thoracic UnitHospital ClínicBarcelona 08036Spain Department of Radiaiton Oncology Hospital Ruber InternacionalMadrid 28034Spain Department of Radiation Oncology Hospital Clínico Universitario Santiago de CompostelaA Coruña 15706Spain Department of Radiation Oncology Hospital Regional Universitario de Málaga29010Spain Department of Radiation Oncology Clínica Universidad de NavarraMadrid 28027Spain

The coronavirus disease 2019 crisis has had a major and highly complex impact on the clinical practice of radiation oncology *** is one of the countries hardest hit by the virus,with devastating *** is an urgent need to share experiences and offer guidance on decision-making with regard to the indications and standards for radiation therapy in the treatment of lung *** the present article,the Oncological Group for the Study of Lung Cancer of the Spanish Society of Radiation Oncology reviews the literature and establishes a series of consensus-based recommendations for the treatment of patients with lung cancer in different clinical scenarios during the present pandemic.

关键词： Lung cancer COVID-19 Pandemic Radiotherapy Recommendations

Characterization of Solid Wastes from Aluminum Tertiary Sector: The Current State of Spanish Industry

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Journal of Minerals and Materials Characterization and Engineering 2015年第2期3卷 55-64页

作者： Roberto Galindo Isabel Padilla Olga rod.íguez Ruth Sánchez-Hernández Sol López-Andrés aurora López-Delgado National Centre for Metallurgical Research CENIM-CSIC Madrid Spain Department of Crystallography and Mineralogy Faculty of Geology UCM Madrid Spain

Aluminum recycling is an important activity that allows returning this metal to the market saving energy and resources. This activity generates slag and dross, both hazardous materials, which are recovered by other industries (tertiary sector). In that process, new wastes are prod.ced, but most of them are disposed in security storage facilities because of their hazardousness and scarce marketable value. In Spain, the statistical data analysis on waste reveals that this sector is increasing every year. This study aims to characterize the wastes generated by the tertiary aluminum industries in Spain. Samples were collected in different aluminum recycling industries and characterized by chemical analyses, X-ray fluorescence, X-ray diffraction and particle size determination. Wastes rich in aluminum oxide and alkaline elements also comprise metallic aluminum and aluminum nitride. Such components are the main responsible for the waste hazardousness since they generate toxic gases in the presence of water. Besides, their fine granulometry (x50 < 30 μm) also contributes highly to the hazardousness.

关键词： Hazardous Aluminum Waste Characterization Recycling Slag/Dross

Nitrapyrin effectiveness in reducing nitrous oxide emissions decreases at low doses of urea in an Andosol

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Pedosphere 2021年第2期31卷 303-313页

作者： Mayela MONGE-MUÑOZ Segundo URQUIAGA Christoph MÜLLER Juan Carlos CAMBRONEROHEINRICHS Mohammad ZAMAN Cristina CHINCHILLA-SOTO Azam BORZOUEI Khadim DAWAR Carlos E.rod.Íguez-rod.Íguez Ana Gabriela PÉREZ-CASTILLO Environmental Pollution Research Center(CICA) University of Costa RicaMontes de Oca 11501(Costa Rica) Embrapa Agrobiology Rod.BR 465km 7SeropédicaRJCEP 23891-000(Brazil) Institute of Plant Ecology Justus Liebig University GiessenHeinrich-Buff Ring 26Giessen 35392(Germany) School of Biology and Environmental Science University College DublinBelfieldDublin 4(Ireland) Soil and Water Management&Crop Nutrition Section Joint FAO/IAEA Division of Nuclear Techniques in Food and AgricultureDepartment of Nuclear Sciences and ApplicationsInternational Atomic Energy AgencyVienna International CentreVienna 1400(Austria) Nuclear Agriculture Research School Nuclear Science and Technology Research Institute(NSTRI)Karaj ***(Iran) Department of Soil and Environmental Sciences University of AgriculturePeshawar 25000(Pakistan)

In the tropics,frequent nitrogen(N)fertilization of grazing areas can potentially increase nitrous oxide(N_(2)O)*** application of nitrification inhibitors has been reported as an effective management practice for potentially reducing N loss from the soil-plant system and improving N use efficiency(NUE).The aim of this study was to determine the effect of the co-application of nitrapyrin(a nitrification inhibitor,NI)and urea in a tropical Andosol on the behavior of N and the emissions of N_(2)O from autotrophic and heterotrophic nitrification.A greenhouse experiment was performed using a soil(pH 5.9,organic matter content 78 g kg^(-1),and N 5.6 g kg^(-1))sown with Cynodon nlemfuensis at 60%water-filled pore space to quantify total N_(2)O emissions,N_(2)O derived from fertilizer,soil ammonium(NH_(4)^(+))and nitrate(NO_(3)^(-)),and *** study included treatments that received deionized water only(control,NI).No significant differences were observed in soil NH_(4)^(+)content between the UR and UR+NI treatments,probably because of soil mineralization and NO_(3)^(-)prod.ced by heterotrophic nitrification,which is not effectively inhibited by *** 56 d,N_(2)O emissions in UR(0.51±0.12 mg N_(2)O-N concluded that the soil organic N mineralization and heterotrophic nitrification are the main processes of NH_(4)^(+)and NO_(3)^(-)***,it was found that N_(2)O emissions were partially a consequence of the direct oxidation of the soil's organic N via heterotrophic nitrification coupled to ***,the results suggest that nitrapyrin would likely exert significant mitigation on N_(2)O emissions only if a substantial N surplus exists in soils with high organic matter content.

关键词： autotrophic nitrification heterotrophic nitrification mineral N ^(15)N tracer nitrification inhibitor tropical grass

New challenges in the combination of radiotherapy and immunotherapy in non-small cell lung cancer

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World Journal of Clinical Oncology 2021年第11期12卷 983-999页

作者： Javier Luna Juan Zafra Ma Carmen Areses Manrique aurora rod.íguez Amalia Sotoca Jose Luis Fírvida rod.lfo Chicas-Sett Xabier Mielgo Juan Carlos Trujillo Reyes Felipe Couñago Department of Radiation Oncology Oncohealth InstituteFundación Jiménez DíazMadrid 28040Spain Department of Radiation Oncology Dr.Negrín University Hospital of Gran CanariaLas Palmas 35010Spain Department of Medical Oncology Ourense University HospitalOurense 32005Spain Department of Radiation Oncology Ruber International HospitalMadrid 28034Spain Department of Medical Oncology Hospital Universitario Fundación AlcorcónAlcorcón 28922Spain Department of Thoracic Surgery Hospital de la Santa Creu i Sant PauBarcelona 08029Spain Department of Radiation Oncology Hospital Universitario QuirónSalud MadridHospital La LuzUniversidad Europea de MadridMadrid 28223Spain

Immunotherapy has represented one of the main medical revolutions of recent decades,and is currently a consolidated treatment for different types of tumors at different stages and scenarios,and is present in a multitude of clinical *** of the diseases in which it is most developed is non-small cell lung *** combination of radiotherapy and immunotherapy in cancer in general and lung cancer in particular currently represents one of the main focuses of basic and clinical research in oncology,due to the synergy of this interaction,which can improve tumor response,resulting in improved survival and disease *** this review we present the biochemical and molecular basis of the interaction between radiotherapy and *** also present the current clinical status of this interaction in each of the stages and cases of non-small cell lung cancer,with the main results obtained in the different studies both in terms of tumor response and survival as well as ***,we mention the main studies underway and the challenges of this interaction in the coming years,including how these treatments should be combined to achieve the greatest efficacy with the fewest possible side effects(dose,type of radiotherapy and drugs,sequence of treatments).

关键词： Lung cancer Radiotherapy Immunotherapy Main trials

GOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma

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World Journal of Clinical Oncology 2021年第8期12卷 581-608页

作者： Javier Luna Andrea Bobo Joaquín José Cabrera-rod.iguez María Pagola Margarita Martín-Martín María Ángeles González Ruiz Miguel Montijano aurora rod.íguez Lira Pelari-Mici Almudena Corbacho Marta Moreno Felipe Couñago Department of Radiation Oncology Institute of OncohealthFundación Jiménez DíazMadrid 28040Spain Department of Radiation Oncology Institution of Ruber Internacional HospitalMadrid 28034Spain Department of Radiation Oncology Hospital Universitario de BadajozBadajoz 06080Spain Department of Radiation Oncology Institution of Onkologikoa/Hospital Universitario DonostiaSan Sebastián 20014Spain Department of Radiation Oncology Institution of Hospital Universitario Ramón y CajalMadrid 28034Spain Department of Radiation Oncology Institution of Hospital Universitario Virgen de la MacarenaSevilla 41009Spain Department of Radiation Oncology Institution of Genesis care SpainMadrid 28005Spain Department of Radiation Oncology Institution of Hospital de MéridaMérida 06800Spain Department of Oncology Institution of University NavarraClinical UniversityPamplona 31008Spain Department of Radiation Oncology Institution of Hospital Universitario Quirónsalud and Hospital LaLuzEuropean University of MadridMadrid 28028Spain

Malignant pleural mesothelioma(MPM)is a rare tumor with poor prognosis and rising *** care is common in MPM as radical treatment with curative intent is often not possible due to metastasis or extensive locoregional *** therapeutic advances have been made in recent years,including the use of less aggressive surgical techniques associated with lower morbidity and mortality(e.g.,pleurectomy/decortication),technological advancements in the field of radiotherapy(intensity-modulated radiotherapy,image-guided radiotherapy,stereotactic body radiotherapy,proton therapy),and developments in systemic therapies(chemotherapy and immunotherapy).These improvements have had as yet only a modest effect on local control and *** in the management of MPM and standardization of care are hampered by the evidence to date,limited by high heterogeneity among studies and small sample *** this clinical guideline prepared by the oncological group for the study of lung cancer of the Spanish Society of Radiation Oncology,we review clinical,histologic,and therapeutic aspects of MPM,with a particular focus on all aspects relating to radiotherapy,including the current evidence base,associations with chemotherapy and surgery,treatment volumes and planning,technological advances,and reradiation.

关键词： Malignant pleural mesothelioma Chemotherapy Surgery Radiotherapy Radiation techniques Reradiation

Characterization of yogurt goat milk added Aloe vera and Stevia rebaudiana with functional potential

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Food and Health 2023年第4期5卷 16-23页

作者： Mariela Enriquez Mario Cruz Rosa Mrod.íguez-Jasso Araceli Loredo-Treviño aurora Garza Ruth Belmares Autonomous University of Coahuila Blvd.V.Carranza and Engineer JoséCárdenas s/n Col.Republic C.P.25280SaltilloCoahuilaMexico Autonomous Agrarian University Antonio Narro Calzada Antonio Narro 1923BuenavistaC.P.25315 SaltilloCoahuilaMexico Autonomous University of Nuevo León Faculty of Public Health and NutritionAvenida Dr.Eduardo Aguirre Pequeño and YuririaCol.Mitras CentroC.P.64460MonterreyN.L.Mexico.

The search for functional foods with health benefits has increased,and yogurt represents one of these prod.cts due to their properties,such as,source of probiotics that favour the gastrointestinal system,contains vitamins,minerals and improves the action of *** work investigated bromatological,microbiological,sensorial properties and shelf-life of different yogurt goat milk formulations with Aloe vera and natural *** goat yogurt with 99.40%*** pulp and 0.60%*** presented the best nutritional composition,being suitable for human consumption representing an innovative prod.ct with a great functional *** synergy between the ingredients used in the yogurt processing resulted in an innovative prod.ct to the *** milk has a lower cost per liter in comparison with cow milk,Aloe vera is accessible due to its fast-vegetative propagation,Stevia Rebaudiana has a great popularity for being a natural sweetener with no calories,and all these prod.cts are prod.ced in México.

关键词： Aloe vera functional food goat milk pulp Stevia rebaudiana yogurt.

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

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Cellular & Molecular Immunology 2021年第9期18卷 2128-2139页

作者： Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-rod.iguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-rod.íguez E Clinical Unit of Infectious Diseases Microbiology and Preventive MedicineInstitute of Biomedicine of Seville(IBiS)Virgen del Rocío University HospitalCSICUniversity of SevilleSevilleSpain Department of Medical Biochemistry Molecular Biologyand ImmunologySchool of MedicineUniversity of SevilleSevilleSpain Pneumology Service Galicia Sur Health Research Instituto(IIS Galicia Sur)SERGAS-UVigoVigoSpain Infectious Diseases Unit Department of Internal MedicineComplexo HospitalarioUniversitario de VigoIIS Galicia SurSERGAS-UVigoVigoSpain Group of Virology and Pathogenesis Galicia Sur Health Research Institute(IIS Galicia Sur)-Complexo Hospitalario Universitario de VigoSERGAS-UVigoVigoSpain Unit of Infectious Diseases Microbiologyand Preventive MedicineVirgen del Rocío University HospitalSevilleSpain Institute of Biomedicine of Seville(IBiS) Virgen del Rocío University Hospital/CSIC/University of SevilleSevilleSpain Medico-Surgical Unit of Respiratory Diseases Virgen del Rocío University HospitalSevilleSpain Unit of Emergencies Virgen del Rocío University HospitalSevilleSpain Intensive Care Unit Virgen del Rocío University HospitalSevilleSpain Department of Medicine University of SevilleSevilleSpain Cardiology and Cardiovascular Surgery Unit Virgen del Rocío University HospitalSevilleSpain Rheumatology Unit Virgen del Rocío University HospitalSevilleSpain Internal Medicine Unit Virgen del Rocío University HospitalSevilleSpain Digestive and Hepatobiliary Unit Virgen del Rocío University HospitalSevilleSpain Neurology and Clinical Neurophysiology Unit Virgen del Rocío University HospitalSevilleSpain Endocrinology and Nutrition Unit Virgen del Rocío University HospitalSevilleSpain Urology and Nephrology Unit Virgen del Rocío University HospitalSevilleSpain Unit of Clinical Investigation and Clinical Trials Virgen del Rocío University HospitalSevilleSpain

Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity *** cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to prod.ce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αprod.ction,which has been associated with disease *** this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory ***,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 ***,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were *** findings contribute to a better understanding of the immunological sequelae of COVID-19.

关键词： SARS-CoV-2 COVID-19 Dendritic cell Long-COVID

Effect of the sintering technique on the ferroelectric and d33 piezoelectric coefficients of Bi0.5(Na0.84K0.16)0.5TiO3 ceramic

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Journal of Advanced Ceramics 2019年第2期8卷 278-288页

作者： G.HERNANDEZ-CUEVAS J.R.LEYVA MENDOZA P.E.GARCíA-CASILLAS C.A.rod.íguez GONZáLEZ J.F.HERNANDEZ-PAZ G.HERRERA-PéREZ L.FUENTES-COBAS S.DíAZ DE LA TORRE O.RAYMOND-HERRERA H.CAMACHO-MONTES Instituto de Ingeniería y Tecnología Universidad Autónoma de Ciudad JuárezAv.Del Charro 450 Norte Cd.JuárezChihuahua32310México Centro de Investigación en Materiales Avanzados Miguel de Cervantes 120Chihuahua 31109ChihuahuaMéxico Centro de Investigación e Innovación Tecnológica Instituto Politécnico NacionalCerrada de Cecati s/nAzcapotzalcoSanta Catarina02250Ciudad de MéxicoMéxico Centro de Nanociencias y Nanotecnología Universidad Nacional Autónoma de MéxicoKm.107 Carretera Tijuana-EnsenadaAP.14Ensenada 22860Baja CaliforniaMéxico

In the search of lead-free piezoelectric materials,ceramic processing techniques offer potential tools to increase the piezoelectric and ferroelectric properties in addition to new chemical *** of pure BNKT16(Bi0.5(Na0.84K0.16)0.5TiO3)phase were synthesized by sol–gel method with a low crystallization temperature(750℃).Ceramic samples were sintered by pressureless sintering(PLS),sinter-forging(SF),and spark plasma sintering(SPS)***,morphological,and chemical characterizations were performed by XRD,Raman,EDS,and *** samples by PLS and SF exhibit rod.like grains associated to bismuth *** highest remanent polarization(11.05μC/cm2),coercive field(26.2 kV/mm),and piezoelectric coefficient(165 pC/N)were obtained for SF *** piezoresponse force microscopy(PFM)analysis shows that the crystallites at the nanoscale exhibit piezoelectric phenomenon and the highest piezoelectric response is reported for PLS *** presence of the rhombohedral phase,the increase in grain and crystallite size,and the oriented rod.like inclusions favoring the crystallographic texture are facts that enhance the piezoelectric coefficient for BNKT16 piezoceramics.

关键词： lead-free piezoelectrics sol–gel pressureless sintering (PLS) sinter-forging (SF) spark plasma sintering(SPS) piezoresponse