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Journal of Modern Power Systems and Clean Energy 2023年第4期11卷 1269-1281页

作者： Sauro J.Yague aurelio garcía-cerrada Pere Palacín Farré IQS School of Engineering Ramón Llull UniversityVia Augusta 39008017 BarcelonaSpain Institute for Research in Technology ICAI School of EngineeringComillas Pontifical UniversityAlberto Aguilera 2328015 MadridSpain

Stability in unbalanced power systems has deserved little attention in the *** the importance of this scenario in distribution systems with distributed generation,this paper revisits modal analysis techniques for stability studies in power systems,and explains how to tackle unbalanced power systems with voltage-dependent *** procedure is described in detail and applied to a low-voltage(LV)simple case study with two grid-forming electronic power converters and unbalanced *** are then compared with those obtained with the popular impedance-based *** the latter is easier to implement using simulation or field data,the former requires complete information of the system,but gives a better insight into the *** both methods are based on a small-signal approximation of the system,they provide similar results,but they discern different information.A larger second case study based on an LV CIGRE distribution system is also *** are obtained using a detailed Simulink model of the microgrids with electronic power converters.

关键词： Stability microgrid modal analysis impedancebased method unbalanced distribution system

Comprehensive control for unified power quality conditioners

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Journal of Modern Power Systems and Clean Energy 2017年第4期5卷 609-619页

作者： Miguel OCHOA-GIMéNEZ aurelio garcía-cerrada Juan Luis ZAMORA-MACHO Gamesa Electric S.A. 28823 CosladaMadridSpain School of Engineering Comillas Pontifical University28015 MadridSpain

This paper presents a comprehensive control strategy for unified power quality conditioners(UPQCs) to compensate for both voltage and current quality *** controllers for the series and shunt components of the UPQC are, equally, divided into three blocks: à main controller, which deals with the fundamental-frequency issues such as active and reactive power flow;` harmonic controller, which ensures zero-error tracking while compensating voltage and current harmonics;′ the set-point generation block, which handles the different control objectives of the UPQC. The controller design procedure has been simplified to the selection of three parameters for each converter. Furthermore, the proposed strategy can be implemented measuring only four variables, which represents a reasonable number of sensors. In addition, a pulse width modulation(PWM)-based modulation with fixed switching frequency is used for both converters. The proposed control strategy has been validated experimentally under different conditions, including grid-frequency variations.

关键词： Unified power quality conditioner(UPQC) Powerquality Harmoniccontrol Pulse width modulation(PWM)

Mesenchymal stem cells,secretome and biomaterials in in-vivo animal models:Regenerative medicine application in cutaneous wound healing

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BIOCELL 2022年第8期46卷 1815-1826页

作者： MASSIMO CONESE aurelio PORTINCASA Department of Medical and Surgical Sciences University of FoggiaFoggia71122Italy Department of Clinical and Experimental Medicine University of FoggiaFoggia71122Italy

The treatment of nonhealing and chronic cutaneous wounds still needs a clinical advancement to be *** mesenchymal stem cells(MSCs),obtained from different sources,and their secretome derived thereof(especially exosomes)can activate signaling pathways related to promotion of cell migration,vascularization,collagen deposition,and inflammatory response demonstrating prohealing,angiogenetic and anti-scarring *** the other hand,biodegradable biomimetic scaffolds can facilitate endogenous cell attachment and proliferation as well as extracellular matrix *** this Review,we revise the complex composites made by biomimetic scaffolds,mainly hydrogels,and MSC-derived exosomes constructed for cutaneous wound *** demonstrate that there exists a synergistic action of scaffolds with encapsulated exosomes,displaying a sustained release profiles to facilitate longlasting healing *** can be envisioned that dressings made by biomimetic hydrogels and MSC-derived exosomes will be clinically applied in the near future for the effective treatment of nonhealing and chronic wounds.

关键词： Biomimetic scaffolds Cutaneous wound healing Exosomes Hydrogels Mesenchymal stem cells Secretome

Compressing deep-quaternion neural networks with targeted regularisation

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CAAI Transactions on Intelligence Technology 2020年第3期5卷 172-176页

作者： Riccardo Vecchi Simone Scardapane Danilo Comminiello aurelio Uncini Department of Information Engineering Electronics and Telecommunications(DIET)‘Sapienza’University of RomeRoma Lazio 00185Italy

In recent years,hyper-complex deep networks(such as complex-valued and quaternion-valued neural networks–QVNNs)have received a renewed interest in the *** find applications in multiple fields,ranging from image reconstruction to 3D audio *** to their real-valued counterparts,quaternion neural networks require custom regularisation strategies to avoid *** addition,for many real-world applications and embedded implementations,there is the need of designing sufficiently compact networks,with few weights and ***,the problem of regularising and/or sparsifying QVNNs has not been properly addressed in the literature as of *** this study,the authors show how to address both problems by designing targeted regularisation strategies,which can minimise the number of connections and neurons of the network during *** this end,they investigate two extensions of ℓ1 and structured regularisations to the quaternion *** the authors’experimental evaluation,they show that these tailored strategies significantly outperform classical(realvalued)regularisation approaches,resulting in small networks especially suitable for low-power and real-time applications.

关键词： networks neural valued

Core-softened potentials, multiple liquid-liquid critical points, and density anomaly regions： An exact solution

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Frontiers of physics 2018年第1期13卷 85-94页

作者： Eduardo O. Rizzatti Marco aurelio A. Barbosa Marcia C. Barbosa Instituto de Fisica Universidade Federal do Rio Grande do Sul Porto Alegre-RS Brazil Programa de Pos-Graduacao em Ciencia de Materiais Universidade de Brasilia Planaltina-DF Brazil

The pressure versus temperature phase diagram of a shoulder-like potential is exactly computed in one system of particles interacting through a multiscale dimension. The N-shoulder potential exhibits N density anomaly regions in the phase diagram if the length scales can be connected by a convex curve The result is analyzed in terms of the convexity of the Gibbs free energy.

关键词： density anomalies regions

An elastin-like recombinamer-based bioactive hydrogel embedded with mesenchymal stromal cells as an injectable scaffold for osteochondral repair

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Regenerative Biomaterials 2019年第6期6卷 335-347页

作者： Filippo Cipriani Blanca Arino Palao Israel Gonzalez de Torre aurelio Vega Castrillo Hector Jose Aguado Hernandez Matilde Alonso Rodrigo Angel Jose Alvarez Barcia Ana Sanchez Veronica garcıa Diaz Monica Lopez Pena Jose Carlos Rodriguez-Cabello Technical Proteins Nanobiotechnology S.L. Paseo Belen 9AValladolid 47011Spain Departamento de traumatologıa Hospital Clınico de ValladolidAv.Ramon y Cajal 3Valladolid 47003Spain Bioforge University of Valladolid CIBER-BBNPaseo de Belen 19Valladolid 47011Spain SIBA-UVA:servicio investigacion y bienestar animal University of ValladolidC/Plaza de Santa Cruz 8Valladolid 47002Spain Instituto de Biologıa y Genetica Molecular(IBGM) Universidad de Valladolid y CSICCalle Sanz y Fores 3Valladolid 47003Spain Facultad de veterinaria Campus UniversitarioAvda.Carballo Calero s/nLugo 27002Spain

The aim of this study was to evaluate injectable,in situ cross-linkable elastin-like recombinamers(ELRs)for osteochondral *** the ELR-based hydrogel alone and the ELR-based hydrogel embedded with rabbit mesenchymal stromal cells(rMSCs)were tested for the regeneration of critical subchondral defects in 10 New Zealand ***,cylindrical osteochondral defects were filled with an aqueous solution of ELRs and the animals sacrificed at 4months for histological and gross evaluation of features of biomaterial performance,including integration,cellular infiltration,surrounding matrix quality and the new matrix in the *** both approaches helped cartilage regeneration,the results suggest that the specific composition of the rMSC-containing hydrogel permitted adequate bone regeneration,whereas the ELR-based hydrogel alone led to an excellent regeneration of hyaline *** conclusion,the ELR cross-linker solution can be easily delivered and forms a stable well-integrated hydrogel that supports infiltration and de novo matrix synthesis.

关键词： biopolymer animal test cartilage bone

Transcriptome Analysis Provides Novel Insights into Salt Stress Response in Two Egyptian Rice Varieties with Different Tolerance Levels

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Rice science 2022年第6期29卷 499-502页

作者： Shehab MOHAMED Iovene MARINA Ciancio aurelio Colagiero MARIANTONIETTA Finetti-Sialer MARIELLA Rice Research and Training Center Field Crops Research InstituteAgriculture Research CenterSakha Kafr El-Sheikh 33717Egypt Institute of Biosciences and Bioresources National Research CouncilBari 70126Italy Sustainable Plant Protection Institute National Research CouncilBari 70126Italy

The response of rice to salt stress(200 mmol/L NaCl)was investigated at the transcription level in Egyptian varieties Giza 177(salt sensitive variety)and Giza 178(salt tolerant variety).We applied a genome-wide RNA-Se... 详细信息

关键词： varieties Egyptian stress

Comparison of Air Pollution−Mortality Associations Using Observed Particulate Matter Concentrations and Reanalysis Data in 33 Spanish Cities

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Environment & Health 2024年第3期2卷 161-169页

作者： Dominic Royé Carmen Íñiguez aurelio Tobías Climate Research Foundation 28003 MadridSpainSpanish Consortium for Research on Epidemiology and Public Health(CIBERESP)28029 MadridSpain Institute of Environmental Assessment and Water Research(IDAEA) Spanish Council for Scientific Research(CSIC)08034 BarcelonaSpain

Air pollution poses a health hazard in all ***,complete data on ambient particulate matter(PM)concentrations are not available in all world *** data is already a valuable source of exposure data in epidemiological studies examining the relationship between temperature and ***,the performance of reanalysis data in assessing the short-term health effects of particulate air pollution remains *** assessed the performance of CAMS reanalysis(EAC4)data from the European Centre for Medium-Range Weather Forecasts,compared with daily PM concentrations from field monitoring stations,to estimate short-term exposure to PM with an aerodynamic diameter less than 10μm(PM_(10))on daily mortality in 33 Spanish provincial capital cities using a two-stage time series regression *** shape of the PM_(10)distribution varied substantially between PM observations and CAMS global reanalysis of atmospheric composition(EAC4)reanalysis data,with correlation ranging from 0.21 to *** pooled mortality risk for a 10μg/m^(3)increase in PM_(10)showed similar estimates using PM concentrations{relative risks(RR)=1.007,95%confidence intervals(95%CI)=[1.002,1.011]}and EAC4 reanalysis data(RR=1.011,95%CI=[1.006,1.015]).However,the city-specific PM_(10)beta coefficients estimated using PM concentrations and EAC4 reanalysis data showed a low correlation(r=0.22).The use of reanalysis data should be approached with caution when assessing the association between particulate matter air pollution and health outcomes,particularly in cities with small populations.

关键词： Air pollution particulate matter PM_(10) reanalysis EAC4 mortality Spain time series regression

Percutaneous electrochemotherapy in the treatment of portal vein tumor thrombosis at hepatic hilum in patients with hepatocellular carcinoma in cirrhosis: A feasibility study

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World Journal of Gastroenterology 2017年第5期23卷 906-918页

作者： Luciano Tarantino Giuseppina Busto aurelio Nasto Raffaele Fristachi Luigi Cacace Maria Talamo Catello Accardo Sara Bortone Paolo Gallo Paolo Tarantino Riccardo aurelio Nasto Matteo Nicola Dario Di Minno Pasquale Ambrosino Department of Surgery Interventional Hepatology UnitAndrea Tortora Hospital Department of Oncology Andrea Tortora Hospital Department of Surgery Unit of General Surgery and OncologyAndrea Tortora Hospital Department of Pathology Andrea Tortora Hospital Department of Radiology Andrea Tortora Hospital Department of Advanced Biomedical Sciences Division of CardiologyFederico II University Unit of Cell and Molecular Biology in Cardiovascular Diseases Centro Cardiologico MonzinoIRCCS Department of Clinical Medicine and Surgery Federico II University

AIMTo treated with electrochemotherapy (ECT) a prospective case series of patients with liver cirrhosis and Vp3-Vp4- portal vein tumor thrombus (PVTT) from hepatocellular carcinoma (HCC), in order to evaluate the feasibility, safety and efficacy of this new non thermal ablative technique in those *** patients (5 males and 1 female), aged 61-85 years (mean age, 70 years), four in Child-Pugh A and two in Child-Pugh B class, entered our study series. All patients were studied with three-phase computed tomography (CT), contrast enhanced ultrasound (CEUS) and ultrasound-guided percutaneous biopsy of the thrombus before ECT. All patients underwent ECT treatment (Cliniporator Vitae®, IGEA SpA, Carpi, Modena, Italy) of Vp3-Vp4 PVTT in a single session. At the end of the procedure a post-treatment biopsy of the thrombus was performed. Scheduled follow-up in all patients entailed: CEUS within 24 h after treatment; triphasic contrast-enhanced CT and CEUS at 3 mo after treatment and every six months ***-treatment CEUS showed complete absence of enhancement of the treated thrombus in all cases. Post-treatment biopsy showed apoptosis and necrosis of tumor cells in all cases. The follow-up ranged from 9 to 20 mo (median, 14 mo). In 2 patients, the follow-up CT and CEUS demonstrated complete patency of the treated portal vein. Other 3 patients showed a persistent avascular non-tumoral shrinked thrombus at CEUS and CT during follow-up. No local recurrence was observed at follow-up CT and CEUS in 5/6 patients. One patient was lost to follow-up because of death from gastrointestinal hemorrage 5 wk after *** patients with cirrhosis, ECT seems effective and safe for curative treatment of Vp3-Vp4 PVTT from HCC.

关键词： Hepatocellular carcinoma Portal vein tumor thrombosis Electrochemotherapy

Passive Smoking and Infectious Disease: A Serious Hazard for Cardiovascular System

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International Journal of Clinical Medicine 2011年第5期2卷 550-555页

作者： aurelio Leone 不详

Exposure to passive smoking is usually associated with heavy changes in both function and structure of the cardiovascular system at different levels: coronary circulation, heart metabolism, myocardial muscle. These changes may be transient but may have characteristics of irreversibility. Major determinant of cardiovascular alterations is hypoxia due to tobacco products of the environment although a large number of alterations affect immune t-cells and antibody response. All infectious diseases which involve cardiovascular system, including some tropical patterns, particularly Chagas disease, are adversely influenced as a consequence of a continuous although irregular exposure to passive smoking, which worsens the degree of cardiac muscle alterations at different levels like myocardium, coronary arteries and both these structures. Therefore, exposure to passive smoking must be avoided for those individuals suffering from infectious diseases of the heart whatever factor can be responsible.

关键词： Passive Smoking Tropical Disease Heart