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Numerical modeling of bedload and suspended load contributions to morphological evolution of the Seine Estuary(France)

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International Journal of Sediment Research 2021年第6期36卷 723-735页

作者： Baptiste Mengual Pierre Le Hir aurélie rivier Matthieu Caillaud Florent Grasso IFREMER DYNECO/DHYSED Laboratory Centre de Bretagne UMR 7266 lieNSs CNRS-La Rochelle University IRSN (Institut de Radioprotection et de S?reté Nucléaire) PRP-ENV/SERIS/LRC Laboratory

This numerical modeling study(i) assesses the influence of the sediment erosion process on the sediment dynamics and subsequent morphological changes of a mixed-sediment environment, the macrotidal Seine estuary, when non-cohesive particles are dominant within bed mixtures(non-cohesive regime), and(ii) investigates respective contributions of bedload and suspended load in these dynamics.A three dimensional(3 D) process-based morphodynamic model was set up and run under realistic forcings(including tide, waves, wind, and river discharge) during a 1-year period. Applying erosion homogeneously to bed sediment in the non-cohesive regime, i.e., average erosion parameters in the erosion law(especially the erodibility parameter, E0), leads to higher resuspension of fine sediment due to the presence of coarser fractions within mixtures, compared to the case of an independent treatment of erosion for each sediment class. This results in more pronounced horizontal sediment flux(two-fold increase for sand, +30% for mud) and erosion/deposition patterns(up to a two-fold increase in erosion over shoals, generally associated with some coarsening of bed sediment). Compared to observed bathymetric changes, more relevant erosion/deposition patterns are derived from the model when independent resuspension fluxes are considered in the non-cohesive regime. These results suggest that this kind of approach may be more relevant when local grain-size distributions become heterogeneous and multimodal for non-cohesive particles. Bedload transport appears to be a non-dominant but significant contributor to the sediment dynamics of the Seine Estuary mouth. The residual bedload flux represents, on average, between 17 and 38% of the suspended sand flux, its contribution generally increasing when bed sediment becomes coarser(can become dominant at specific locations). The average orientation of residual fluxes and erosion/deposition patterns caused by bedload generally follow those resulting from

关键词： Non-cohesive sand-mud mixtures Erosion Suspended sediment transport Bedload transport Morphodynamics Seine Estuary

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Blood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults

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Stroke & Vascular Neurology 2023年第5期8卷 358-367页

作者： Julián N Acosta Stefan P Haider Cyprien rivier Audrey C Leasure Kevin N Sheth Guido J Falcone Seyedmehdi Payabvash Department of Neurology Yale School of MedicineNew HavenConnecticutUSA Department of Radiology and Biomedical Imaging Yale School of MedicineNew HavenConnecticutUSA Department of Otorhinolaryngology Ludwig Maximilians University MunichMunchenGermany

Background and objectives We aimed to investigate the white matter(WM)microstructural/cytostructural disintegrity patterns related to higher systolic blood pressure(SBP),and whether they mediate SBP effects on cognitive performance in middle-aged *** Using the UK Biobank study of community-dwelling volunteers aged 40-69 years,we included participants without a history of stroke,dementia,demyelinating disease or traumatic brain *** investigated the association of SBP with MRI diffusion metrics:fractional anisotropy(FA),mean diffusivity(MD),intracellular volume fraction(a measure of neurite density),isotropic(free)water volume fraction(ISOVF)and orientation dispersion across WM ***,we determined whether WM diffusion metrics mediated the effects of SBP on cognitive *** We analysed 31363 participants-mean age of 63.8 years(SD:7.7),and 16523(53%)*** SBP was associated with lower FA and neurite density,but higher MD and *** different WM tracts,diffusion metrics of the internal capsule anterior limb,external capsule,superior and posterior corona radiata were most affected by higher *** seven cognitive metrics,SBP levels were only associated with‘fluid intelligence’(adjusted p<0.001).In mediation analysis,the averaged FA of external capsule,internal capsule anterior limb and superior cerebellar peduncle mediated 13%,9%and 13%of SBP effects on fluid intelligence,while the averaged MD of external capsule,internal capsule anterior and posterior limbs,and superior corona radiata mediated 5%,7%,7%and 6%of SBP effects on fluid intelligence,*** Among asymptomatic adults,higher SBP is associated with pervasive WM microstructure disintegrity,partially due to reduced neuronal count,which appears to mediate SBP adverse effects on fluid *** metrics of select WM tracts,which are most reflective of SBP-related parenchymal damage and cognitive impairment,may serve as imaging biomarkers to

关键词： capsule Blood impairment

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Protein Quality of Amaranth Grains Cultivated in Ethiopia as Affected by Popping and Fermentation

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Food and Nutrition Sciences 2015年第1期6卷 38-48页

作者： Endale Amare Claire Mouquet-rivier Adrien Servent Gilles Morel Abdulaziz Adish Gulelat Desse Haki Wolaita Sodo University Wolaita Sodo Ethiopia Center for Food Science and Nutrition Addis Ababa University Addis Ababa Ethiopia IRD UMR 204 “Prévention des Malnutritions et des Pathologies Associées” (Nutripass) IRD/Montpellier 2/Montpellier 1 Montpellier France CIRAD Département Persyst UMR Qualisud Montpellier France Micronutrient Initiative Addis Ababa Ethiopia

The effect of popping and fermentation on protein quality of three different varieties of amaranth grains cultivated in Ethiopia was evaluated. Total lysine content of the grains was higher than that of commonly available cereals but close to that of legumes. Methionine and cysteine contents in the grains were also higher than that found in cereal and legume proteins. Percentage of total indispensable amino acids, excluding tryptophan, was 43% - 49%, which was higher than WHO reference pattern (31%). Popping resulted in 36% and 37% reduction in total lysine and cysteine contents, respectively, whereas fermentation reduced cysteine, lysine and methionine contents by 16%, 20% and 20%, respectively. From the free amino acids, histidine was the major indispensable amino acid but threonine was not detected. During popping, all free amino acids, except threonine, were reduced. On the other hand, fermentation significantly increased (p < 0.01) most amino acids except arginine, which was significantly decreased (p < 0.01), and tyrosine and glutamic acid, for which no change was observed. Popping decreased in vitro protein digestibility (IVPD) by 8.3% - 17.1% while fermentation increased IVPD by 4.8% - 7.5%. Substitution of amaranth for wheat and/or maize during complementary food formulation could contribute much to the daily requirements of indispensable amino acids of young children.

关键词： Amaranth Grain Indispensable Amino Acids Popping Fermentation Protein Digestibility Complementary Food

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THE EX-PRESS MINIATURE GLAUCOMA IMPLANT IN COMBINED SURGERY WITH CATARACT EXTRACTION: PROSPECTIVE STUDY

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国际眼科杂志 2003年第1期3卷 106-107页

作者： A.Mermoud D.rivier Hopital Ophtalmique Jules Gonin University of Lausanne SwitzerlandHopital Ophtalmique Jules Gonin University of Lausanne Switzerland

The Ex-PRESS (Optonol Ltd.) is a miniature stainless steel glaucoma implant with a 50-micron internal lumen. A single-center, open, non-comparative case series was performed to evaluate the safety and efficacy of the Ex-PRESS in reducing IOP in open angle glaucoma patients. Thirty-six Caucasian patients with OAG and vision impairing cataract were

关键词：青光眼微型Ex-PRESS埋植物白内障摘除术疗效安全性

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中国、日本磨芋产业的现状、困因与发展趋势分析

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天然产物研究与开发 1998年第4期10卷 80-86页

作者：何家庆安徽省磨芋技术研究中心合肥230039

本文以中国与日本磨芋产业的历史、现状为背景,讨论了四个问题。第一,中国与日本磨芋种植业的现状与困因;第二,中国与日本磨芋加工业的现状与困因;第三,中国与日本磨芋产品流通的相关性;第四,中国与日本磨芋产业的发展趋势。

关键词：磨芋产业中国日本存在问题发展趋势

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Ito型色素镶嵌现象揭示20三倍体镶嵌性

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世界核心医学期刊文摘（皮肤病学分册） 2005年第7期1卷 32-32页

作者： Girard C. Guillot B. rivier F. 田中伟(译) Service de Dermatologie H?opital Saint-Eloi 80 avenue Augustin Fliche 34295 Montpellier Cedex 5 France

Introduction. Ito hypomelanosis-type pigmentary mosaicism is characterized by congenital pigmentation disorders along Blaschko’ s lines. We report a case of Ito-type pigmentary mosaicism associated with a congenital growth hormone deficiency having revealed trisomy 20 mosaicism. Observation. A 4 year-old boy presented with congenital pigmentation disorders. His history was marked by: inter-uterine delayed growth of unknown etiology, a dysmorphic syndrome, psychomotor retardation with speech problems, right cryptorchidia and an isolated, idiopathic, congenital growth hormone deficiency that had been treated with recombinant somatropine since the age of three. The clinical examination revealed alternating hypo and hyper-pigmented maculae with linear distribution on the limbs and in “ twirls" on the trunk following Blaschko’ s lines. The blood karyotypewas normal, the karyotype on fibroblasts of hypopigmented skin revealed trisomy 20 mosaicism. Discussion. The occurrence of pigmentary mosaicism related to trisomy 20 mosaicism is exceptional. The combination of Ito hypomelanosis-type pigmentary mosaicism and delayed growth due to growth hormone deficiency has never been reported before. Our observation, unusual because of such an association, raises the question of the eventual existence of associated genes located on the chromosome 20 implied in the secretion of growth hormone and/or melanogenesis. It also underlines the interest of conducting cytogenic explorations on fibroblasts of damaged skin in the case of Ito-type pigmentary mosaicism, even if the blood karyotype is normal or in the absence of a patent phenotype abnormality.

关键词：镶嵌现象 Ito 镶嵌性生长激素缺乏精神运动性阻滞染色体组型促生长素抑制素隐睾黑素成纤维细胞

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