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国外作物育种 2003年第3期22卷 21-21页

作者： Y.Bougot J.lemoine 谢国禄

Lancet Gastroenterol Hepatol:新研究称全球有近3亿乙肝病毒携带者,仍无根治药

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疾病监测 2018年第2期33卷 94-94页

作者： Shimakawa Y Seck A Nayagam S Toure-Kane C lemoine M

英国《柳叶刀·胃肠病与肝脏病学》杂志日前发表的一项新研究显示，2016年全球有近3亿乙肝病毒携带者。美国等国研究人员根据此前多项研究数据和多名各国专家意见，通过建模研究发现，2016年全球约2．92亿人是乙肝病毒携带者，约占全球... 详细信息

英国《柳叶刀·胃肠病与肝脏病学》杂志日前发表的一项新研究显示，2016年全球有近3亿乙肝病毒携带者。美国等国研究人员根据此前多项研究数据和多名各国专家意见，通过建模研究发现，2016年全球约2．92亿人是乙肝病毒携带者，约占全球人口总数的近4％。其中，东亚和撒哈拉以南地区乙肝病毒携带者最为常见。

关键词：乙肝病毒携带者 Lancet 撒哈拉以南地区根治肝脏病学专家意见研究人员胃肠病

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1997年香港回归中国对亚洲工业化地区的影响（一）

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非肿瘤黏膜基因表达谱可预测结肠癌患者的临床预后

国际贸易研究 1995年第8期

作者：热摩娃(F.lemoine)

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世界核心医学期刊文摘（胃肠病学分册） 2006年第5期2卷 18-18页

作者： Barrier A. Boelle P.-Y. lemoine A. 陈云茹 Division of Biostatistics School of Public Health 140 Earl Warren Hall Berkeley CA 94720-7360 United States Dr.

PURPOSE: This study assessed the possibility to build a prognosis predictor, based on microarray gene expression measures, in Stage II and III colon cancer patients. METHODS: Tumor and nonneoplastic mucosa mRNA samples from 12 colon cancer patients were profiled using the Affymetrix HGU133A GeneChip. Six of 12 patients experienced a metachronous metastasis, whereas the 6 others remained disease-free for more than five years. Three datasets were constituted, including, respectively, the gene expression measures in tumor samples (T), in adja-cent nonneoplastic mucosa samples (A), and the log-ratio of the gene expression measures (L). The step-down procedure of Westfall and Young and the k-nearest neighbor class prediction method were applied on T, A, and L. Leave-one-out cross-validation was used to estimate the generalization error of predictors based on different numbers of genes and neighbors. RESULTS: The most frequent results were one false prediction with the A-based predictors (95 percent) and two false predictions with the T-and l-based predictors (65 and 60 percent, respectively). A-based predictors were more stable (i.e., less sensitive to changes of parameters, such as numbers of genes and neighbors) than T-and l-based predictors. Informative genes in A-based predictors included genes involved in the oxidative and phosphorylative mitochondrial metabolism and genes involved in cell-signaling pathways and their receptors. CONCLUSIONS: This study suggests that one can build a prognosis predictor for Stage II and III colon cancer patients, based on microarray gene expression measures, and suggests the potential usefulness of nonneoplastic mucosa for this purpose.

关键词：基因表达谱癌患者非肿瘤预测法临床预后结肠黏膜 Affymetrix 预测因素基因芯片检测

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支气管结核在肺结核病中的地位

中华结核和呼吸杂志 1957年第1期05卷 62-62页

作者： J. M. lemoine: Schweiz. Z. Tuberk. 孙艮生(摘)

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妊娠性滋养层细胞瘤治疗的手术范围(法)

世界核心医学期刊文摘（妇产科学分册） 2006年第9期2卷 51-51页

作者： Sergent F. Verspyck E. lemoine J.-P. Marpeau L. 马超 Clinique Gynécologique et Obstétricale Pavillon Mère-Enfant Hpital Charles-Nicolle 1 rue de Germont 76031 Rouen CedexFrance

Gestational trophoblastic tumors are authentic malignant tumors of the conception. They are mostly chemosensitive. For young women, the place of the surgery seems now restricted and more and more codified. Hysterectomy keeps a certain interest for women who do not wish to preserve their fertility. Hysterectomy limits then the complications of chemotherapy. It optimizes the chances of recovery without recurrence. If chemotherapy must nevertheless be carried out, hysterectomy decreases the necessary number of cures to obtain complete remission of the disease. Surgery is also indispensable to chemoresistant tumors. It allows exeresis of localized residual sites or isolated metastases. Other indications for surgery include uncontrollable vaginal or intra- abdominal bleedings and placental site trophoblastic tumors.

关键词：滋养层细胞瘤手术范围瘤治疗妊娠性子宫切除术妊娠滋养细胞瘤化疗敏感保留生育能力

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Emotional categorization: Individual emotional differences and laterality effects in healthy and persons with multiple sclerosis

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