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Journal of Environmental Sciences 2017年第1期29卷 256-264页

作者： audrey Murray Banu rmeci Edward P.c.Lai Department of civil and Environmental Engineering Carleton University Department of chemistry Carleton University

Endocrine disrupting compounds（EDcs） and pharmaceuticals pose a challenge for water and wastewater treatment because they exist at very low concentrations in the presence of substances at much higher concentrations competing for adsorption ***-micron sized resin particles（approximately 300 nm in diameter）（SMR） were tested to evaluate their potential as a treatment for EDcs including：17-β estradiol（E2）,17-α ethinylestradiol（EE2）,estrone（E1）,bisphenol A（BPA）,and diethylstilbestrol（DES） as well as 12 *** were able to remove 98%of spiked E2,80%of EE2,87%of BPA,and up to 97%of DES from *** a 0.5 ppm mixture of E2,EE2,E1,BPA and DES,the minimum removal was24%（E2） and the maximum was 49%（DES）.They were also able to remove the pharmaceuticals from deionized water and ***,SMR are a promising advanced treatment for removal of both EDcs and pharmaceuticals.

关键词： Water treatment Wastewater treatment Pharmaceuticals Endocrine disrupting compounds Micropollutants Adsorption

Open land-use map:a regional land-use mapping strategy for incorporating OpenStreetMap with earth observations

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Geo-Spatial Information Science 2017年第3期20卷 269-281页

作者： Di Yang chiung-Shiuan Fu audrey c.Smith Qiang Yu Department of Geography University of FloridaGainesvilleFLUSA Land Use and Environmental change Institute University of FloridaGainesvilleFLUSA Beijing Key Laboratory of Precision Forestry Beijing Forestry UniversityBeijingChina

A land-use map at the regional scale is a heavy computation task yet is critical to most landowners,researchers,and decision-makers,enabling them to make informed decisions for varying *** are two major difficulties in generating land classification maps at the regional scale:the necessity of large data-sets of training points and the expensive computation cost in terms of both money and *** Geographic Information opens a new era in mapping and visualizing the physical world by providing an open-access database valuable georeferenced information collected by volunteer *** one of the most well-known VGI initiatives,OpenStreetMap(OSM),contributes not only to road network distribution information but also to the potential for using these data to justify and delineate land ***,most large-scale mapping approaches-including regional and national scales–confuse“land cover”and“land-use”,or build up the land-use database based on modeled land cover data-sets,in this study,we clearly distinguished and differentiated land-use from land *** focusing on our prime objective of mapping land-use and management practices,a robust regional land-use mapping approach was developed by integrating OSM data with the earth observation remote sensing *** novel approach incorporates a vital temporal component to large-scale land-use mapping while effectively eliminating the typically burdensome computation and time/money demands of such ***,our novel approach in regional scale land-use mapping produced robust results in our study area:the overall internal accuracy of the classifier was 95.2%and the external accuracy of the classifier was measured at 74.8%.

关键词： OpenStreetMap(OSM) Volunteered Geographic Information(VGI) crowdsourced data Random Forest Google Earth Engine(GEE)

What do we know about parasitic plants and the leaf economic spectrum?

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Journal of Plant Ecology 2022年第4期15卷 691-699页

作者： audrey F.Haynes Department of Integrative Biology University of California BerkeleyBerkeleyCA 94720USA

The leaf economic spectrum(LES)quantifes correlations between key leaf traits across vascular plants and distills much of the variation in these traits to a single *** LES,remarkable in its near universality,has been extensively researched across a variety of ***,parasitic plants relationship to the LES framework remains relatively *** the LES is,in part,driven by physiological tradeoffs in the acquisition of carbon(c),in theory heterotrophy in parasitic plants,which supplants some of the essential functions of leaves,could lead to departures from the *** global leaf trait data from the TRY database,this work assessed the overall representation of parasitic plants in the TRY database,then compared the LES suite of leaf traits in parasitic plants to their non-parasitic *** their unique physiology,parasitic plants did not deviate dramatically from the LES,although there were examples of differences in position on the LES and relationships among *** more importantly,parasitic plants are not well represented in the TRY database,making any conclusions here premature.

关键词： parasitic plants leaf economic spectrum TRY database leaf traits

Lights at night:does photobiomodulation improve sleep?

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Neural Regeneration Research 2023年第3期18卷 474-477页

作者： audrey Valverde catherine Hamilton cécile Moro Malvina Billeres Pierre Magistretti John Mitrofanis UniversitéGrenoble Alpes FDD and CEA-LETIClinatecGrenobleFrance WellRed Inc LauncestonTasmaniaAustralia King Abdullah University of Science and Technology Thuwal Saudi Arabia Institute of Ophthalmology University College LondonLondonUK

Sleep is a critical part of our daily *** impacts every organ and system of our body,from the brain to the heart and from cellular metabolism to immune function.A consistent daily schedule of quality of sleep makes a world of difference to our health and *** its importance,so many individuals have trouble sleeping *** quality sleep has such a detrimental impact on many aspects of our lives;it affects our thinking,learning,memory,and ***,and most poignantly,poor quality sleep over time increases the risk of developing a serious medical condition,including neurodegenerative *** this review,we focus on a potentially new non-pharmacological treatment that improves the quality of *** treatment,called photobiomodulation,involves the application of very specific wavelengths of light to body *** animal models,these wavelengths,when applied at night,have been reported to stimulate the removal of fluid and toxic waste-products from the brain;that is,they improve the brain’s inbuilt house-keeping *** suggest that transcranial nocturnal photobiomodulation,by improving brain function at night,will help improve the health and well-being of many individuals,by enhancing the quality of their sleep.

关键词： aquaporin 4 glymphhatic infrared non-pharmacological red sleep cap transcranial wakefulness

Aminopeptidase A and dipeptidyl peptidase 4:a pathogenic duo in Alzheimer’s disease?

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Neural Regeneration Research 2022年第10期17卷 2215-2217页

作者： Frédéric checler audrey Valverde Universitécôte d’Azur INSERMCNRSIPMCteam labelled“Laboratory of Excellence(LABEX)DistAlz”ValbonneFrance

The etiology of Alzheimer’s disease is far from being completely *** approaches have helped in this matter and have greatly supported the view that theβ-amyloid precursor protein(βAPP)could be at the center of gravity of the ***,mutations responsible for autosomal dominant aggressive forms of Alzheimer’s disease(AD)are all harbored by eitherβAPP itself or by its cleaving enzyme presenilins 1/2 referred to asγ-*** was therefore convincing to note that fully independent gene products harboring AD-linked mutations,all concur to modulateβAPP proteolytic *** genetic clues combined with a bulk of anatomical observations and cellular manipulations pointed to the role of amyloid-β(Aβ),the main biochemical component of senile plaques that accumulate at late stages of ***,a series of clinical trials designed to either abolish Aβproduction or neutralize it once produced have consistently failed(checler et al.,2021).

关键词： Alzheimer Aβ senile

Bioluminescent fungi from Peninsular Malaysia-a taxonomic and phylogenetic overview

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Fungal Diversity 2015年第1期70卷 149-187页

作者： audrey L.c.chew Dennis E.Desjardin Yee-Shin Tan Md Yusoff Musa Vikineswary Sabaratnam Mushroom Research centre University of Malaya50603 Kuala LumpurMalaysia Institute of Biological Sciences Faculty of ScienceUniversity of Malaya50603 Kuala LumpurMalaysia Department of Biology San Francisco State University1600 Holloway Ave.San FranciscoCA 94132USA

Fifteen bioluminescent fungi recently collected from Peninsular Malaysia are analysed *** phylogeny of the Malaysian bioluminescent fungi and closely related taxa were evaluated with molecular data from the nuclear ribosomal large subunit(LSU),RNA polymerase 2 second largest subunit(RPB2)and internal transcribed spacers(ITS)gene *** sequences data support the circumscription of species based on the morphological species concept,but was unable to fully support the current sectional delimitation of genus *** the 15 taxa analysed here,four are novel species described herein,*** gombakensis,***,*** and Panellus luxfilamentus;while four taxa of Mycena *** were recently described as *** species(***)represents a new distribution record to Peninsular Malaysia,and six species(Neonothopanus nambi,Filoboletus manipularis,***,Roridomyces pruinosoviscidus,*** and ***)have been previously *** pruinosoviscidus is accepted as a new combination based on morphological and phylogenetic *** morphology data indicate its potential for taxon delimitation as axenic cultures of each species produced unique and distinguishable *** descriptions,illustrations and photographs are provided on basidiome and culture morphology.A key to aid in species identification,comparisons with allied species and data on basidiome and mycelium luminescence are also *** study gives the first report on mycelial luminescence for ***,***,*** as well as all new species described *** reports in this study bring the total known luminescent fungi worldwide to 81 species.

关键词： Basidiomycete Biodiversity culture morphology Filoboletus Mycena Neonothopanus Panellus Phylogeny Roridomyces Systematics Taxonomy

Blood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults

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Stroke & Vascular Neurology 2023年第5期8卷 358-367页

作者： Julián N Acosta Stefan P Haider cyprien Rivier audrey c Leasure Kevin N Sheth Guido J Falcone Seyedmehdi Payabvash Department of Neurology Yale School of MedicineNew HavenConnecticutUSA Department of Radiology and Biomedical Imaging Yale School of MedicineNew HavenConnecticutUSA Department of Otorhinolaryngology Ludwig Maximilians University MunichMunchenGermany

Background and objectives We aimed to investigate the white matter(WM)microstructural/cytostructural disintegrity patterns related to higher systolic blood pressure(SBP),and whether they mediate SBP effects on cognitive performance in middle-aged *** Using the UK Biobank study of community-dwelling volunteers aged 40-69 years,we included participants without a history of stroke,dementia,demyelinating disease or traumatic brain *** investigated the association of SBP with MRI diffusion metrics:fractional anisotropy(FA),mean diffusivity(MD),intracellular volume fraction(a measure of neurite density),isotropic(free)water volume fraction(ISOVF)and orientation dispersion across WM ***,we determined whether WM diffusion metrics mediated the effects of SBP on cognitive *** We analysed 31363 participants-mean age of 63.8 years(SD:7.7),and 16523(53%)*** SBP was associated with lower FA and neurite density,but higher MD and *** different WM tracts,diffusion metrics of the internal capsule anterior limb,external capsule,superior and posterior corona radiata were most affected by higher *** seven cognitive metrics,SBP levels were only associated with‘fluid intelligence’(adjusted pcapsule,internal capsule anterior limb and superior cerebellar peduncle mediated 13%,9%and 13%of SBP effects on fluid intelligence,while the averaged MD of external capsule,internal capsule anterior and posterior limbs,and superior corona radiata mediated 5%,7%,7%and 6%of SBP effects on fluid intelligence,*** Among asymptomatic adults,higher SBP is associated with pervasive WM microstructure disintegrity,partially due to reduced neuronal count,which appears to mediate SBP adverse effects on fluid *** metrics of select WM tracts,which are most reflective of SBP-related parenchymal damage and cognitive impairment,may serve as imaging biomarkers to

关键词： capsule Blood impairment

The Rise of china As A Major Host Destination for International Student Education

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The Rise of China As A Major Host Destination for Internatio...

作者： audrey Yee 上海交通大学

学位级别：硕士

International student mobility figures have exponentially increased over the years,doubling from 2.1 million in 2000 to close to 5 million in 2014 *** OEcD projects this figure to reach 8 million in *** opening up its market in 1978 and making rapid developments in its economy,china has seen remarkable progress in its education *** much so,it has recently emerged as one of the top ten destinations for international students *** central objective of this paper hence,is to examine the rise of china as major host destination for international student *** the theoretical approach of a developmental state,china’s rise would be attributed to its strategies employed by the chinese state and universities that are used to enhance or create its attraction factors（otherwise known as “pull” factors）as identified in international student opinion surveys,that are of economic,educational and socio-cultural *** supplementing the above primary objective,the paperthen demonstrates that china’s success in the international student education market owing to the choice of strategies and motivations are indeed ***,itdeviates from the global neo-liberalism ideology,which otherwise sees pursuit of economic gain as ***-medium master programmes are also an emerging trend amongst chinese universities in attracting international *** paper will add on to the scarce literature available by prescribing some exploratory factors as to why some of these new programmes are more successful in attracting international students than others,through case studies of four such programmes that are from two c9 universities.

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A cross-sectional Real-life Study of the Prevalence,Severity,and Determinants of Metabolic Dysfunction-associated Fatty Liver Disease in Type 2 Diabetes Patients

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Journal of clinical and Translational Hepatology 2023年第6期11卷 1377-1386页

作者： Quentin Binet audrey Loumaye Michel P Hermans Nicolas Lanthier Service d’Hépato-Gastroentérologie Cliniques universitaires Saint-LucUCLouvainBrusselsBelgium Service d’Endocrinologie et Nutrition Cliniques universitaires Saint-LucUCLouvainBrusselsBelgium

Background and Aims:Most data on liver assessment in type 2 diabetes mellitus(T2DM)patients are from retrospective cohorts with selection *** aimed at appraising the feasibility,results,and benefits of an outpatient systematic noninvasive screening for metabolic dysfunction-associated fatty liver disease(MAFLD)severity and determinants in T2DM ***:We conducted a 50-week crosssectional study enrolling adult T2DM outpatients from a diabetes *** algorithm based on guidelines was applied using simple bioclinical scores and,if applicable,ultrasound and/or ***:Two hundred and thirteen patients were *** age and body mass index were 62 years and 31 kg/m^(2) and 29% of patients had abnormal transaminase *** acceptance rate of additional liver examinations was 92%.The prevalence of MAFLD,advanced fibrosis and cirrhosis was 87%,11%,and 4%,*** than half of the cases of advanced fibrosis had not been suspected and were detected by this *** was associated with poor glycemic control,elevated transaminases,low HDL-c and the absence of peripheral arterial *** fibrosis was linked to high waist circumference and excessive alcohol consumption,which should be interpreted with caution owing to the small number of patients reporting excessive ***:Simple bioclinical tools allowed routine triage of T2DM patients for MAFLD severity,with high adherence of high-risk patients to subsequent noninvasive exams.

关键词： Noninvasive tests MAFLD Outpatient Steatosis Fibrosis

Interleukin 7 regulates switch transcription in developing B cells

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cellular & Molecular Immunology 2021年第3期18卷 776-778页

作者： audrey Dauba Fatima-Zohra Braikia chloe Oudinet Ahmed Amine Kham lichi Mnstitut de Pharmacologie et de Biologie Structurale IPBSUniversite de ToulouseCNRSUniversity Paul Sabatier31077 ToulouseFrance

class switch recombination(cSR)enables activated mature B cells to change immunoglobulin(Ig)isotype expression from IgM to IgG,IgE,or *** process requires activation-induced cytidine deaminase(AID)expression and transcription of the target sequences at the Ig heavy chain(IgH)constant locus,which is composed of multiple constant(c_(H))genes,each specifying an Ig isotype.

关键词： Interleukin enable IgH