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The Investigation of the Fractional-View Dynamics of Helmholtz Equations Within Caputo Operator

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Computers, Materials & Continua 2021年第9期68卷 3185-3201页

作者： Rashid Jan Hassan Khan Poom Kumam Fairouz Tchier rasool Shah Haifa Bin Jebreen Department of Mathematics and Statistics Bacha Khan UniversityCharsadda24420Pakistan Department of Mathematics Abdul Wali Khan UniversityMardan23200Pakistan Department of Mathematics Near East University TRNCMersin10Turkey Center of Excellence in Theoretical and Computational Science(TACS-CoE)&Department of Mathematics Faculty of ScienceKing Mongkut’s University of Technology Thonburi(KMUTT)126 Pracha-Uthit RoadBang ModThung Khru10140BangkokThailand Department of Medical Research China Medical University HospitalChina Medical UniversityTaichung 40402Taiwan Mathematics Department King Saud UniversityRiyadhSaudi Arabia

It is eminent that partial differential equations are extensively meaningful in physics,mathematics and *** phenomena are formulated with partial differential equations and are solved analytically or numerically to interrogate the system’s dynamical *** the present research,mathematical modeling is extended and the modeling solutions Helmholtz equations are discussed in the fractional view of ***,the Helmholtz equations are presented in Caputo’s fractional *** Natural transformation,along with the decomposition method,is used to attain the series form solutions of the suggested *** justification of the proposed technique,it is applied to several numerical *** graphical representation of the solutions shows that the suggested technique is an accurate and effective technique with a high convergence rate than other *** less calculation and higher rate of convergence have confirmed the present technique’s reliability and applicability to solve partial differential equations and their systems in a fractional framework.

关键词： Fractional-order Helmholtz equations fractional calculus natural transform decomposition method analytic solution

Pharmacological evaluation of smooth muscle relaxant and cardiac-modulation potential of Phyla nodiflora in ex-vivo and in-vivo experiments

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Asian Pacific Journal of Tropical Medicine 2017年第12期10卷 1146-1153页

作者： Hafiz Muhammad Abdur Rahman Khaled Ahmed Muhammad Fawad rasool Imran Imran Faculty of Pharmacy Bahauddin Zakariya University60800MultanPakistan

Objective: To investigate the pharmacological basis of its uses of Phyla nodiflora(P. nodiflora) for the treatment of anomalies predominantly by smooth muscle containing tissues such as gastrointestinal/vascular/broncho spasm and cardiovascular ***: The crude hydroalcoholic extract of P. nodiflora(***) and its fractions were evaluated on isolated rabbit jejunum, rat trachea, aorta and atrium. To access the contractile or relaxant effects of testing materials, the tissues were mounted in isolated organ bath and responses were recorded with transducers coupled with data acquisition ***/c mice were challenged with castor oil for the assessment of in-vivo antidiarrheal activity. Normotensive rats were used for in-vivo hypotensive ***: Hydroalcoholic extract of *** at variable concentrations inhibited the natural spontaneous rhythm and 80 mmol/L K^+ mediated contractions in isolated segment of jejunum with EC_(50) values of 3.18 and 1.91 mg/mL respectively. Verapamil, a Ca^(2+) channel blocker, demonstrated akin pattern in jejunum and therefore possibly suggesting calcium blocking activity. On isolated rat tracheal tissue, *** showed relaxation of high-K^+and carbachol mediated contractions(EC_(50) values: 1.24 and 2.42 mg/mL). *** treatment relaxed the rat aortic ring in a cumulative doses with high-K^+ and phenylephrine-induced contractions(EC_(50) values 0.25 and 0.92 mg/mL). Activity based fractionation of *** showed that dichloromethane fraction was more potent for relaxing the tissues spasm compared to aqueous fraction. In-vivo experiments, significant protection by ***(P < 0.05) was observed in castor oil-induced diarrhea(50–500 mg/kg)whereas hypotensive effect in anesthetized rats was seen at the dose range of 1–10 mg/kg of ***(P < 0.05).Conclusion: This study suggests the blockage of calcium channel in the smooth muscles as a pharmacological application to make usage of P. nodiflora in the management of diarrhea, as

关键词： Phyla nodiflora Calcium channel blocking activity Antidiarrheal Antiasthmatic Hypotensive

Effects of irrigation water regime, soil clay content and their combination on growth,yield,and water use efficiency of rice grown in South China

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International Journal of Agricultural and Biological Engineering 2018年第4期11卷 144-155页

作者： Yousef Alhaj Hamoud Xiangping Guo Zhenchang Wang Sheng Chen Ghulam rasool Key Laboratory of High-Effective Irrigation and Drainage and Agricultural Water and Soil Environment in Southern China Ministry of EducationHohai UniversityNanjing 210098JiangsuChina Department of Soil and Land Reclamation Aleppo UniversityAleppo 1319Syria

To investigate the effect of irrigation regime,soil clay content and their combination on growth,yield,and water productivity of rice,a shelter experiment was conduct using Randomized Complete Block Design(RCBD)with a factorial arrangement of treatments with four *** regime was the main treatment investigated,set in three levels as R(30 mm-100%)(100%of saturation and 30 mm flooded),R(30 mm-90%)(90%of saturation and 30 mm flooded)and R(30 mm-70%)(70%saturation and 30 mm flooded),*** sub-treatment was soil type,set in three levels as 40%,50%and 60%clay content,*** showed that irrigation regime and soil clay content had significant effects on growth,yield and water productivity of ***,their combination showed no significant impact on panicles number,root biomass,harvest index and irrigation water *** soil clay content results in increase in growth,yield,and water productivity of *** total water consumption during R(30 mm-100%)was higher than that during R(30 mm-90%)and R(30 mm-70%)because the latter two saturation levels led to the cracking of soil and decrease of total number of *** were consistently getting more serious with the reduction in soil water content and the increase in soil clay *** in soil will preferentially become the major routes of water losses,thus water percolation during R(30 mm-70%)was higher than that during R(30 mm-90%)and R(30 mm-100%)after each irrigation *** total water use under R(30 mm-70%)exceeded the water consumption under R(30 mm-90%)due to the great amount of soil cracking as well as the excessive volume of standing water *** water consumption and grain yield,the following conclusion can be reached:(i)The reduction in water consumption was greater than the reduction in grain yield in the case of drying soil 10%below saturation before reflooding.(ii)The reduction in water consumption was less than the reduction i

关键词： irrigation regime clay content combination growth yield water productivity rice

Purification and characterization of CHpro1, a thermotolerant, alkali-stable and oxidation-resisting protease of Chumathang hotspring

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Science Bulletin 2015年第14期60卷 1252-1260页

作者： Reena Singh Chirag Chopra Vishnu Kumar Gupta Bashir Akhlaq Vijeshwar Verma Shafaq rasool School of Biotechnology Shri Mata Vaishno Devi University Lovely Professional University Indian Institute of Toxicology Research

Metagenomic approaches are recently used for searching novel open reading frames （ORFs） coding enzymes employed in pharmaceutical, rood industries, etc. In this study, a metagenornic library was constructed from Chumathang hotspring sediment DNA. The library consisted of approximately 9,000 clones and was screened for protease activity. A clone exhibiting protease activity was identified and named CHprol. Sequencing of CHprol revealed that the ORF encoded a functional protein of 363 amino acids belonging to peptidase S8-S53 superfamily. CHprol shared 41% sequence similarity with a reported protease （subtilase family） and 35 % structural similarity with the crystal structure of Pro-Tk sps. of Thermococcus kodarkaenasis. In silico modeling the 3D structure of CHprol showed that it has two beta sheets, 10 alpha helices and 11 strands. Catalytic triad prediction implied CHprol to be a serine protease. The optimum temperature and pH of the purified protease were found to be 80 ℃ and 11.0, respectively. The enzyme was active at 5 % concentration of hydrogen peroxide and retained 60 % of activity at 10 % concentration. The thermotolerant, alkalophilic and oxidant stable properties of the protease make it a potential can- didate for biotechnological applications.

关键词： Thermotolerant. Alkalophilic Oxidantstable Protease Hotspring Metagenomics

Piperine,an active ingredient of black pepper attenuates acetaminophen-induced hepatotoxicity in mice

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Asian Pacific Journal of Tropical Medicine 2010年第12期3卷 971-976页

作者： Evan Prince Sabina Annie Deborah Harris Souriyan Deborah Jackline Mahaboob Khan rasool School of Biological Sciences and Technology VIT University Vellore - 632 014Tamil NaduIndia

Objective:To explore the hepatoprotective and antioxidant effects of piperine against acetaminophen-induced hepatotoxicity in ***:In mice,hepatotoxicity was induced by a single dose of acetaminophen(900 mg/kg b.w.i.p.).Piperine(25 mg/kg b.w.i.p.) and standard drug silymarin(25 mg/kg b.w.i.p.) were given to mice,30 min after the single injection of *** 4 h,the mice were *** of liver marker enzymes [(aspartate transaminase(AST),alanine transaminase(ALT),and alkaline phosphatase(ALP)]and inflammatory mediator tumour necrosis factor-alpha(TNF-α) were estimated in serum,while lipid peroxidation and antioxidant status(superoxide dismutase,catalase,glutathione peroxidase, glutathione reductase,glutathione-s-transferase and glutathione) were determined in liver homogenate of control and experimental ***:Acetaminophen induction(900 mg/kg b.w.i.p.) significantly increased the levels of liver marker enzymes,TNF-α,and lipid peroxidation,and caused the depletion of antioxidant *** and silymarin treatment to acetaminophen challenged mice resulted in decreased liver marker enzymes activity,TNF-αand lipid peroxidation levels with increase in antioxidant ***:The results clearly demonstrate that piperine shows promising hepatoprotective effect as comparable to standard drug silymarin.

关键词： Pipeline Hepatoprotective Antioxidant enzymes Lipid peroxidation TNF-α

Efficacy of boswellic acid on lysosomal acid hydrolases,lipid peroxidation and anti-oxidant status in gouty arthritic mice

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Asian Pacific Journal of Tropical Biomedicine 2012年第2期2卷 128-133页

作者： Evan Prince Sabina Haridas Indu Mahaboobkhan rasool School of Bio Sciences and Technology VIT University Vellore-632 014

Objective:To evaluate the efficacy of boswellic acid against monosodium urate crystal-induced inflammation in ***:The mice were divided into four experimental ***Ⅰserved as control;mice in groupⅡwere injected with monosodium urate crystal;groupⅢconsisted of monosodium urate crystal-induced mice who were treated with boswellic acid(30mg/kg/b.w.);groupⅣcomprised monosodium urate crystal-induced mice who were treated with indomethacin(3mg/kg/b.w.).Paw volume and levels/activities of lysosomal enzymes,lipid peroxidation,anti-oxidant status and inflammatory mediator TNF-αwere determined in control and monosodium urate crystal-induced *** addition,the levels ofβ-glucuronidase and lactate dehydrogenase were also measured in monosodium urate crystal-incubated polymorphonuclear leucocytes(PMNL)in ***:The activities of lysosomal enzymes,lipid peroxidation,and tumour necrosis factor-αlevels and paw volume were increased significantly in monosodium urate crystal-induced mice,whereas the activities of antioxidant status were in turn ***,these changes were modulated to near normal levels upon boswellic acid *** vitro,boswellic acid reduced the level ofβ-glucuronidase and lactate dehydrogenase in monosodium urate crystal-incubated PMNL in concentration dependent manner when compared with control ***:The results obtained in this study further strengthen the anti-inflammatory/antiarthritic effect of boswellic acid,which was already well established by several investigators.

关键词： Boswellic acid Gouty arthritis Indomethacin Lysosomal enzymes Polymorphonuclear leucocytes Monosodium urate Lipid peroxidation Antioxidant status Anti-inflammatory effect Antiarthritic effect Inflammation

Water promoted, microwave-assisted oxidative novel deamination of N-aminoquinazolinones

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Chinese Chemical Letters 2008年第2期19卷 161-165页

作者： M. Arfan rasool Khan Shazia Anjum Shabir Ahmad M. Iqbal Choudhary Institute of Chemical Sciences University of Peshawar Peshawar 25120 Pakistan HEJRIC International Centre for Chemical and Biological Sciences University of Karachi Karachi 75270 Pakistan

A novel deamination of 2-alkyl/aryl 3-amino-4（3H）-quinazolinones series using aqueous KMnO4 under thermal condition and microwave irradiation is described. Compared to thermal condition, significantly higher yields in much shorter times were observed for reactions under microwave irradiation. A plausible mechanism has been proposed for the oxidative water-promoted deamination.

关键词： N-Aminoquinazolinones Oxidative deamination KMnO4 Water Microwave irradiation

Polymorphisms in ghrelin and heparan sulfate proteoglycan genes and their association with diabetic nephropathy in Pakistani population

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Journal of Chinese Pharmaceutical Sciences 2012年第3期21卷 259-264页

作者： Khuram Shehzad Maria rasool Mahjabeen Saleem Mamoona Naz Institute of Biochemistry and Biotechnology University of the Punjab

Diabetic nephropathy(DN),a long term complication of diabetes,is the most common cause of end-stage renal disease,increasing the risk of *** predispositions play an important role in determining the susceptibility of the development of *** sulphate proteoglycan(HSPG) and ghrelin(GH) gene polymorphisms are associated with the risk of DN.T allele frequency of the HSPG gene determined by BamHI polymorphism located in intron 6 may be a risk factor for the development of renal dysfunction in DN(Fisher two tailed test,CI = 95%,d.f.= 29,P = 0.016).The ghrelin gene polymorphism is caused by a cytosine-to-adenine transition in exon 2 of the preproghrelin gene forming Leu72Met *** Pakistani population,the preproghrelin Leu72Met polymorphism was observed to be not associated with diabetic nephropathy in patients as indicated by statistical analysis(CI = 95%,d.f.= 29,P = 0.691).The allelic frequencies of HSPG genetic polymorphism has the potential to be used as diagnostic markers for diabetic nephropathy disease.

关键词： Diabetic nephropathy Ghrelin Heparan sulfate proteoglycan polymorphism Type 2 diabetes mellitus

Nanoscaled MnSnO_(2)@CsPbBr_(3) quantum dots heterostructure photocatalyst as efficient organic pollutants degradation by peroxymonosulfate;DFT calculation

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Journal of Materials Science & Technology 2023年第22期153卷 41-55页

作者： Raqiqa Tur rasool Ghulam Abbas Ashraf Mohsin Pasha Muhammad Farooq Saleem Djamel Ghernaout Mohammed M.Fadhali Hai Guo Department of Physics Zhejiang Normal UniversityJinhuaZhejiang 321004China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China GBA branch of Aerospace Information Research Institute Chinese Academy of SciencesGuangzhou 510700China Chemical Engineering Department College of EngineeringUniversity of Ha’ilPO Box 2440Ha’il 81441Saudi Arabia Chemical Engineering Department Faculty of EngineeringUniversity of BlidaPO Box 270Blida 09000Algeria Department of Physics Faculty of ScienceJazan UniversityJazan 45142Saudi Arabia Department of Physics Faculty of ScienceIbb University 70270Yemen

In this work,we developed a promising photocatalyst in CsPbBr_(3) quantum dots(QDs)because of their exceptional optoelectronic ***,QDs applications in the field of photocatalysis were mainly hampered by their poor stability and insufficient charge transfer ***,a novel and efficient MnSnO_(2)@CsPbBr_(3)(MSO@QDs)nanocomposite was first time effectively designed and synthe-sized by a wet impregnation method for peroxymonosulfate(PMS)activation under the *** newly generated interface phase of QDs between MnSnO_(2)(MSO)showed great potential to improve light ab-sorption,leading to effective separation and transfer of photoelectron-hole *** novel nanocompos-ite MSO@QDs showed great Flurbiprofen(FL)removal efficiency under the PMS/Light *** should be noted that this nanocomposite removed 85.74%of FL in just 70 min,which was almost 1.11 and 2.51 times greater than using pure QDs and pure MSO,*** on thorough measurements of structural analysis,Brunauer-Emmett-Teller(BET),UV-vis spectra,electrochemical impedance spec-troscopy(EIS),transient photocurrent response,and a potential mechanism for organic pollutants degra-dation over MSO@QDs nanocomposite was *** principal reactive species of photoinduced holes(h^(+)),i.e.O_(2)^(˙−),SO_(4)^(˙−),^(˙)OH,and non-radical(^(1)O_(2))were characterized via scavengers’technique and electron paramagnetic resonance(EPR)*** highest photocatalytic performance for the re-moval of MO,MB,and IBU was demonstrated by MSO@QDs nanocomposite/PMS,revealing their excellent ability to remove organic pollutants through ***,the developed nanocompos-ite exhibited good stability in an aqueous *** to computational investigation using the density functional theory(DFT)method,the site’s higher Fukui index f^(0) value corresponds to a greater propensity to be attacked by reactive *** work offers a fresh perspective on developi

关键词： CsPbBr_(3)QDs MnSnO_(2) Peroxymonosulfate Nanocomposite Photocatalyst Organic pollutants DFT