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Primary signet-ring cell carcinoma of the colon at early stage: A case report and a review of the literature

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World Journal of Gastroenterology 2006年第21期12卷 3446-3449页

作者： Kuang-I Fu Yasushi Sano Shigeharu Kato Hiroki Saito atsushi ochiai Takahiro Fujimori Yutaka Saito Takahisa Matsuda Takahiro Fujii Shigeaki Yoshida Division of Gastrointestinal Oncology and Digestive Endoscopy National Cancer Center Hospital East KashiwaChiba 277-8577Japan Department of Surgical and Molecular PathologyDokkyo University School of Medicine880 KitakobaysashiMibuShimotugaTochigi 321-0293Japan Division of Gastrointestinal Oncology and Digestive Endoscopy National Cancer Center Hospital East KashiwaChiba 277-8577Japan Division of Pathology National Cancer Center East Research Institute Chiba 277-8577Japan Department of Surgical and Molecular Pathology Dokkyo University School of Medicine 880 KitakobaysashiMibuShimotugaTochigi 321-0293Japan Division of Endoscopy National Cancer Center Hospital TsukijiTokyo 104-0045Japan

A 67-year-old man, who had undergone surgery to resect multiple gastric cancers 4 years ago, visited our hospital for surveillance colonoscopy. Colonoscopy revealed a discolored, 7-mm in diameter, flat-elevated lesion with central depression in the transverse colon near the splenic flexure. Although the findings of endoscopy and barium enema were suggestive of submucosal invasion, the patient chose to undergo endoscopic mucosal resection. Pathological examination of the resected specimen revealed signet-ring cell carcinoma and a positive surgical margin. A second operation was performed, and no residual tumor or metastasis to lymph nodes was found in the resected specimens. Primary colorectal cancers composed of signet-ring cell carcinoma detected and treated at an early stage are extremely rare. We present a case and review the literature.

关键词： Signet-ring cell carcinoma Early colorectal cancer Endoscopic mucosal resection

自然印记日本Strata/Springscape美容院

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室内设计与装修 2024年第5期 148-149页

作者： Moriyuki ochiai Architects Moriyuki ochiai Architects 日本

在这个项目中,美容院不仅是一个提供美容服务的场所,还是一个沉浸式的自然体验场所。顾客步入店内,仿佛走进了一个由大自然精心雕琢的艺术空间。设计师将地层、土壤、泉水和溪流等元素融入内部装饰之中,创造了一个独一无二的环境。这些... 详细信息

在这个项目中,美容院不仅是一个提供美容服务的场所,还是一个沉浸式的自然体验场所。顾客步入店内,仿佛走进了一个由大自然精心雕琢的艺术空间。设计师将地层、土壤、泉水和溪流等元素融入内部装饰之中,创造了一个独一无二的环境。这些自然元素的使用不仅是为了美观,它们也在传达一种与大自然和谐共存的理念。室内的每一处细节,都可以感受到自然的呼吸和生命力。例如,地板上的纹理仿佛诉说着地层的历史,墙面上的蓝色渐变则如同清澈的泉水在石间流淌。这样的设计,让人们在享受美容服务的同时,也能体验到城市喧嚣中难得一见的宁静和平和。

关键词：内部装饰自然元素沉浸式美容服务美容院自然体验和谐共存

Influence of Microstructures on Aerodynamic Characteristics for Dragonfly Wing in Gliding Flight

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Journal of Bionic Engineering 2019年第3期16卷 423-431页

作者： Sheng Zhang Masayuki ochiai Yuta Sunami Hiromu Hashimoto Micro/Nano Technology Center Tokai University 4-1-1 Kitakaname Hiratsuka-city Kanagawa 259-1292 Japan Department of Mechanical Engineering Tokai University 4-1-1 Kitakaname Hiratsuka-city Kanagawa 259-1292 Japan

In this paper, the functionalities of microstructures for dragonfly wing during gliding flight are investigated. Three dragonfly-mimic airfoil-shaped wings with hybrid structures were designed and fabricated as: flat wing, zigzag-edged wing and zigzag-edged wing with pillar structure. Based on the wind tunnel experiments, the zigzag-edged wing structure significantly reduces the drag force in the gliding flight. Moreover, the drag reduction is more effective on the combination of the surface pillar and zigzag-edged structure. In addition, the zigzag-edged wing structure has less influence of Karman vortex street, and the surface pillars reduce the frictional drag and stabilized the streamline in the lower vortex region. Overall, the microstructure of the dragonfly wing is an important element in the aerodynamic study. These findings can enhance the knowledge of insect-mimic wing structure and facilitate the application of Micro Air Vehicle (MAV) in the gliding flight.

关键词： dragonfly wing vein structure aerodynamics gliding biomimetics

An experimental investigation of transient cavitation control on a hydrofoil using hemispherical vortex generators

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Journal of Hydrodynamics 2021年第6期33卷 1139-1147页

作者： Ebrahim Kadivar Takaho ochiai Yuka Iga Ould el Moctar Ship Technology Ocean Engineering and Transport SystemsUniversity of Duisburg-EssenDuisburgGermany Institute of Fluid Scienece Tohoku UniversitySendaiJapan

Unsteady cavitation causes noise,damage,and performance decline in the marine engineering and fluid machinery ***,finding a method to control the cavitation and its destructive effects is important for the industrial *** this work,we proposed a passive method to control the unsteady behavior of transient cavitation at the medium Reynolds *** this aim,we performed an experimental study using a high-speed camera to analyze the effects of hemispherical vortex generators(VGs)on the cavitation dynamics around a hydrofoil *** addition,the pressure pulsations induced by the collapse of the cavity structures in the wake region of the hydrofoil were captured with a pressure transducer mounted on the wall downstream of the *** results showed that the instability behaviors of the cavity structures on the hydrofoil were mitigated using the proposed cavitation passive control *** addition,the pressure pulsations in the wake region of the hydrofoil were reduced *** can be concluded that the suppression of cavitation instabilities can improve the operating life and reliability of the marine and hydraulic systems.

关键词： Hydrodynamic cavitation cavitation passive control hemispherical vortex generators pressure pulsations high speed observation

Analytical solution for the size of the minimum dominating set in complex networks

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International Journal of Modeling, Simulation, and Scientific Computing 2017年第1期8卷 67-82页

作者： Jose C.Nacher Tomoshiro ochiai Department of Information Science Faculty of Science Toho UniversityMiyama 2-2-1 FunabashiChiba 274-8510Japan Faculty of Social Information Studies Otsuma Women’s University 2-7-1 Karakida Tama-shiTokyo 206-8540Japan

Domination is the fastest-growing field within graph theory with a profound diversity and impact in real-world applications,such as the recent breakthrough approach that identifies optimized subsets of proteins enriched with cancer-related *** its conceptual simplicity,domination is a classical NP-complete decision problem which makes analytical solutions elusive and poses difficulties to design optimization algorithms for finding a dominating set of minimum cardinality in a large ***,we derive for the first time an approximate analytical solution for the density of the minimum dominating set(MDS)by using a combination of cavity method and ultra-discretization(UD)*** derived equation allows us to compute the size of MDS by only using as an input the information of the degree distribution of a given network.

关键词： Minimum dominating set analytical solution statistical methods complex networks

Optimal duration of the early and late recurrence of hepatocellular carcinoma after hepatectomy

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World Journal of Gastroenterology 2015年第4期21卷 1207-1215页

作者： Yusuke Yamamoto Hisashi Ikoma Ryo Morimura Hirotaka Konishi Yasutoshi Murayama Shuhei Komatsu atsushi Shiozaki Yoshiaki Kuriu Takeshi Kubota Masayoshi Nakanishi Daisuke Ichikawa Hitoshi Fujiwara Kazuma Okamoto Chouhei Sakakura Toshiya ochiai Eigo Otsuji Division of Digestive Surgery Department of SurgeryKyoto Prefectural University of MedicineKyoto 6028566Japan Department of Surgery North Medical CenterKyoto Prefectural University of MedicineKyoto 6028566Japan

AIM: To determine the best cut-off value between the early and late recurrence periods after the initial recurrence of hepatocellular carcinoma(HCC).METHODS: The clinical records of 404 patients who underwent macroscopic curative hepatectomy for HCC between 1980 and 2010 were retrospectively examined. We divided the 252 patients experienced a recurrence of HCC into two groups, the early and late recurrence groups using the "minimum P-value" approach. Factors for early recurrence were investigated using all 404 patients, and factors related to late recurrence were investigated in the patients who were confirmed to be recurrence free at the end of the early recurrence ***: For the 252 patients who experienced a recurrence, the optimal cut-off value for differentiating early and late recurrence based on the overall survival after initial recurrence was 17 mo(5-year overall survival after initial recurrence: 15.4% vs 36.3%, P = 0.000018). Cox proportional hazard analysis identified early recurrence(P = 0.003) as one of the independent prognostic factors associated with overall survival after initial recurrence. A logistic regression model showed that an alpha-fetoprotein level > 100 ng/m L(P < 0.001), multiple HCC(P < 0.001), serosal invasion(P = 0.031), and microvascular invasion(P = 0.012) were independent factors associated with early recurrence, whereas the only independent factor related to late recurrence was liver cirrhosis(P = 0.002).CONCLUSION: Seventeen months after hepatectomy is a useful cut-off value between early and late recurrence of HCC based on the prognosis and different etiologies.

关键词： Early recurrence Late recurrence Hepatocellular ca

Post-hepatectomy survival in advanced hepatocellular carcinoma with portal vein tumor thrombosis

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World Journal of Gastroenterology 2015年第1期21卷 246-253页

作者： Yusuke Yamamoto Hisashi Ikoma Ryo Morimura Katsutoshi Shoda Hirotaka Konishi Yasutoshi Murayama Shuhei Komatsu atsushi Shiozaki Yoshiaki Kuriu Takeshi Kubota Masayoshi Nakanishi Daisuke Ichikawa Hitoshi Fujiwara Kazuma Okamoto Chouhei Sakakura Toshiya ochiai Eigo Otsuji Division of Digestive Surgery Department of SurgeryKyoto Prefectural University of MedicineKyoto 6028566Japan Department of Surgery North Medical Center Kyoto Prefectural University of MedicineKyoto 6028566Japan

AIM: To analyze hepatocellular carcinoma(HCC) patients with portal vein tumor thrombosis(PVTT) using the tumor-node-metastasis(TNM) staging ***: We retrospectively analyzed 372 patients with HCC who underwent hepatectomy between 1980 and *** studied the outcomes of HCC patients with PVTT to evaluate the American Joint Committee on Cancer TNM staging system(7th edition) for stratifying and predicting the prognosis of a large cohort of HCC patients after hepatectomy in a *** vein invasion(vp) 1 was defined as an invasion or tumor thrombus distal to the second branch of the portal vein,vp2 as an invasion or tumor thrombus in the second branch of the portal vein,vp3 as an invasion or tumor thrombus in the first branch of the portal vein,and vp4 as an invasion or tumor thrombus in the portal trunk or extending to a branch on the contralateral ***: The cumulative 5-year overall survival(5yr OS) and 5-year disease-free survival(5yr DFS) rates of the 372 patients were 58.3% and 31.3%,*** 5yr DFS and 5yr OS of vp3-4 patients(n = 10) were 20.0%,and 30.0%,respectively,which was comparable with the corresponding survival rates of vp1-2 patients(P = 0.466 and 0.586,respectively).In the subgroup analysis of patients with macroscopic PVTT(vp2-4),the OS of the patients who underwent preoperative transarterial chemoembolization was comparable to that of patients who did not(P = 0.747).There was a significant difference in the DFS between patients with stage Ⅰ HCC and those with stage Ⅱ HCC(5yr DFS 39.2% vs 23.1%,P 100 mg/dL was independently associated with ***: Hepatectomy for vp3-4 HCC results in a survival rate similar to hepatectomy for *** stratified the stage Ⅱ-Ⅲ HCC patients according to prognosis.

关键词： Hepatocellular carcinoma Hepatectomy Portal vein t