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Multi-modal Gesture Recognition using Integrated Model of Motion, Audio and Video

Chinese Journal of Mechanical Engineering 2015年第4期28卷 657-665页

作者： GOUTSU Yusuke KOBAYASHI Takaki OBARA Junya KUSAJIMA Ikuo TAKEICHI Kazunari TAKANO Wataru nakamura Yoshihiko Department of Mechano-Informatics School of Information Science and TechnologyUniversity of Tokyo7-3-1 HongoBunkyo-kuTokyoJapan

Gesture recognition is used in many practical applications such as human-robot interaction, medical rehabilitation and sign language. With increasing motion sensor development, multiple data sources have become available, which leads to the rise of multi-modal gesture recognition. Since our previous approach to gesture recognition depends on a unimodal system, it is difficult to classify similar motion patterns. In order to solve this problem, a novel approach which integrates motion, audio and video models is proposed by using dataset captured by Kinect. The proposed system can recognize observed gestures by using three models. Recognition results of three models are integrated by using the proposed framework and the output becomes the final result. The motion and audio models are learned by using Hidden Markov Model. Random Forest which is the video classifier is used to learn the video model. In the experiments to test the performances of the proposed system, the motion and audio models most suitable for gesture recognition are chosen by varying feature vectors and learning methods. Additionally, the unimodal and multi-modal models are compared with respect to recognition accuracy. All the experiments are conducted on dataset provided by the competition organizer of MMGRC, which is a workshop for Multi-Modal Gesture Recognition Challenge. The comparison results show that the multi-modal model composed of three models scores the highest recognition rate. This improvement of recognition accuracy means that the complementary relationship among three models improves the accuracy of gesture recognition. The proposed system provides the application technology to understand human actions of daily life more precisely.

关键词： gesture recognition multi-modal integration hidden Markov model random forests

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Excited state calculations using variational quantum eigensolver with spin-restricted ansätze and automatically-adjusted constraints

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npj Computational Materials 2023年第1期9卷 2204-2212页

作者： Shigeki Gocho Hajime nakamura Shu Kanno Qi Gao Takao Kobayashi Taichi Inagaki Miho Hatanaka School of Fundamental Science and Technology Faculty of Science and TechnologyKeio UniversityYokohama 223-8522Japan Quantum Computing Center Keio UniversityYokohama 223-8522Japan IBM Quantum–IBM Research Tokyo Tokyo 103-8510Japan Mitsubishi Chemical Corporation Science&Innovation CenterYokohama 227-8502Japan

The ground and excited state calculations at key geometries, such as the Frank–Condon (FC) and the conical intersection (CI)geometries, are essential for understanding photophysical properties. To compute these geometries on noisy intermediate-scalequantum devices, we proposed a strategy that combined a chemistry-inspired spin-restricted ansatz and a new excited statecalculation method called the variational quantum eigensolver under automatically-adjusted constraints (VQE/AC). Unlike theconventional excited state calculation method, called the variational quantum deflation, the VQE/AC does not require the pre-determination of constraint weights and has the potential to describe smooth potential energy surfaces. To validate this strategy,we performed the excited state calculations at the FC and CI geometries of ethylene and phenol blue at the complete active spaceself-consistent field (CASSCF) level of theory, and found that the energy errors were at most 2 kcal mol−1 even on the ibm_kawasakidevice.

关键词： properties quantum variational

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How to Deal with Revolutions in Train Control Systems

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Engineering 2016年第3期2卷 380-386页

作者： Hideo nakamura Department of Computer Engineering College of Science and Technology Nihon University Funabashi Chiba 274-8501 Japan

Train control systems ensure the safety of railways. This paper begins with a summary of the typical train control systems in Japan and Europe. Based on this summary, the author then raises the following question regarding current train control systems： What approach should be adopted in order to enhance the functionality, safety, and reliability of train control systems and assist in commercial operations on railways？ Next, the author provides a desirable architecture that is likely to assist with the development of new train control systems based on current information and communication technologies. A new unified train control system （UTCS） is proposed that is effective in enhancing the robustness and com- petitiveness of a train control system. The ultimate architecture of the UTCS will be only composed of essential elements such as point machines and level crossing control devices in the field. Finally, a pro- cessing method of the UTCS is discussed.

关键词： Train control system Railway signaling Communication-based train control system Automatic train protection and block system

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Effects of α-mangostin on apoptosis induction of human colon cancer

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World Journal of Gastroenterology 2011年第16期17卷 2086-2095页

作者： Ramida Watanapokasin Faongchat Jarinthanan Yukio nakamura Nitisak Sawasjirakij Amornmart Jaratrungtawee Sunit Suksamrarn Department of Biochemistry Faculty of MedicineSrinakharinwirot University Faculty of Medical Technology Rangsit University Clinical Research Center Murayama Medical Center Department of Research North Bangkok University Department of Chemistry Faculty of ScienceSrinakharinwirot University

AIM:To investigate the effect of α-mangostin on the growth and apoptosis induction of human colon cancer ***:The three colorectal adenocarcinoma cell lines tested (COLO 205,MIP-101 and SW 620) were treated with α-mangostin to determine the effect on cell proliferation by MTT assay,cell morphology,chromatin condensation,cell cycle analysis,DNA fragmentation,phosphatidylserine exposure and changing of mitochondrial membrane *** molecular mechanisms of α-mangostin mediated apoptosis were further investigated by Western blotting analysis including activation of caspase cascade,cytochrome c release,Bax,Bid,p53 and Bcl-2 modifying ***:The highest inhibitory effect of α-mangostin on cell proliferation of COLO 205,MIP-101 and SW 620 were 9.74 ± 0.85 μg/mL,11.35 ± 1.12 μg/mL and 19.6 ± 1.53 μg/mL,*** study showed that α-mangostin induced apoptotic cell death in COLO 205 cells as indicated by membrane blebbing,chromatin condensation,DNA fragmentation,cell cycle analysis,sub-G1 peak (P < 0.05) and phosphatidylserine *** executioner caspase,caspase-3,the initiator caspase,caspase-8,and caspase-9 were expressed upon treatment with α-*** studies of apoptotic proteins were determined by Western blotting analysis showing increased mitochondrial cytochrome c release,Bax,p53 and Bmf as well as reduced mitochondrial membrane potential (P < 0.05).In addition,up-regulation of tBid and Fas were evident upon treatment with α-mangostin (P < 0.01).CONCLUSION:α-Mangostin may be effective as an anti-cancer agent that induced apoptotic cell death in COLO 205 via a link between extrinsic and intrinsic pathways.

关键词： α-mangostin Apoptosis Caspases Colon cancer Mitochondria

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Endoscopic ultrasound-guided fine needle aspiration in the differentiation of type 1 and type 2 autoimmune pancreatitis

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World Journal of Gastroenterology 2012年第29期18卷 3883-3888页

作者： Takuya Ishikawa Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Hirosh Matsubara Yuya Itoh Yosuke nakamura Takeshi Hiramatsu Masanao nakamura Ryoji Miyahara Naoki Ohmiya Hidemi Goto Yoshiki Hirooka Department of Gastroenterology Nagoya University Graduate School of Medicine65 Tsuruma-choShowa-kuNagoya 466-8550Japan Department of Endoscopy Nagoya University Hospital65 Tsuruma-choShowa-kuNagoya 466-8550Japan

AIM:To investigate the usefulness of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) in the differentiation of autoimmune pancreatitis(AIP).METHODS:We retrospectively reviewed 47 of 56 AIP patients who underwent EUS-FNA and met the Asian diagnostic *** 47 EUS-FNA specimens,we evaluated the presence of adequate material and characteristic features of lymphoplasmacytic sclerosing pancreatitis(LPSP) and idiopathic duct-centric pancreatitis(IDCP) mentioned in the International Consensus Diagnostic Criteria and examined if these findings make a contribution to the differential diagnosis of type 1 and type 2 AIP.A disposable 22-gauge needle was used for ***:Adequate specimens including pancreatic tissue for differentiating AIP from cancer were obtained from 43 of 47 patients who underwent ***-FNA was performed from the pancreatic head in 21 cases,which is known to be technically difficult when performed by core biopsy;there was no significant difference in the results compared with pancreatic *** of 47 patients met level 1 findings of LPSP and 5 patients met level 2 findings of *** one met level 1 findings of IDCP,but 3 patients met level 2 findings of *** 10 seronegative cases,2 cases were diagnosed with "definitive type 1 AIP",and 3 cases were diagnosed with "probable type 2 AIP" when considering both the level 2 histological findings and response to ***:EUS-FNA is useful in the differentiation of type 1 and type 2 AIP,particularly in seronegative cases.

关键词： Autoimmune pancreatitis Endoscopic ultrasound-guided fine needle aspiration Idiopathic duct centric pancreatitis Lymphoplasmacytic sclerosing pancreatitis Pancreatic cancer

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Influence of chirality on the cyclohexene-fused C_(60) fullerene derivatives as an accepter partner in a photovoltaic cell

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Green Energy & Environment 2016年第2期1卷 149-155页

作者： Kiyotaka Sugawara Naoshi nakamura Yu Yamane Shuichi Hayase Toshiki Nokami Toshiyuki Itoh Department of Chemistry and Biotechnology Graduate School of Engineering Tottori University Center for Research on Green Sustainable Chemistry Tottori University

Organic photovoltaic devices(OPVs) using chiral cyclohexene-fused [C_(60)]-fullerene derivatives that have(l)-menthyl ester moiety have been prepared and their properties evaluated as acceptor molecules with P3 HT polymer: racemic cyclohexene-fused [C_(60)] fullenene,(RS)-(1 R,2 S,5 R)-2 a showed higher PCE(2.81%) than that of standard [C_(60)]-PCBM(2.64%) under the same analysis conditions. On the contrary, devices using chiral(R)-(1 R,2 S,5 R)-2 a and(S)-(1 R,2 S,5 R)-2 a, showed PCE as 1.08% and 1.10%, respectively. The main origin of the differences in PCE was found to be their poor Jsc values. The results indicate that the aggregation state might influence the interaction state with P3 HT and impact the results of the OPV properties, Jsc values in particular.

关键词： Solar cell Accepter molecule Cyclohexene-fused[C60]-fullerene Chirality

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Methylation-mediated gene silencing as biomarkers of gastric cancer:a review

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World Journal of Gastroenterology 2014年第34期20卷 11991-12006页

作者： Jun nakamura Tomokazu Tanaka Yoshihiko Kitajima Hirokazu Noshiro Kohji Miyazaki Department of Surgery Saga University Faculty of MedicineSaga 849-8501Japan Department of Surgery National Hospital Organization Higashi-Saga Hospital7324 HarakogaMiyaki TownSaga 849-0101Japan

Despite a decline in the overall incidence of gastric cancer(GC),the disease remains the second most common cause of cancer-related death worldwide and is thus a significant global health *** best means of improving the survival of GC patients is to screen for and treat early ***,GC is often diagnosed at an advanced stage and is associated with a poor *** diagnostic and therapeutic strategies have not been successful in decreasing the global burden of the disease;therefore,the identification of reliable biomarkers for an early diagnosis,predictive markers of recurrence and survival and markers of drug sensitivity and/or resistance is urgently *** initiation and progression of GC depends not only on genetic alterations but also epigenetic changes,such as DNA methylation and histone *** DNA methylation is the most well-defined epigenetic change in human cancers and is associated with inappropriate gene ***,an increasing number of genes methylated at the promoter region have been targeted as possible biomarkers for different purposes,including early detection,classification,the assessment of the tumor prognosis,the development of therapeutic strategies and patient *** review article summarizes the current understanding and recent evidence regarding DNA methylation markers in GC with a focus on the clinical potential of these markers.

关键词： Gastric cancer Methylation Biomarker Early detection Drug sensitivity

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Genome-wide microarray screening for Bombyx mori genes related to transmitting the determination outcome of whether to produce diapause or nondiapause eggs

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Insect Science 2017年第2期24卷 187-193页

作者： Shion Akitomo Yuichi Egi Yuki nakamura Yoshitaka Suetsugu Katsutaka Oishi Katsuhiko Sakamoto Graduate School of Agricultural Science Kobe University Kobe Insect Genome Research Unit Agrogenomics Research Center National Institute of Agrobiological Sciences (NIAS) Tsukuba Biological Clock Research Group Biomedical Research Institute National Institute of Advanced Industrial Science and Technology (AIST) Tsukuba Japan

The bivoltine silkworm Bombyx mori （Lepidoptera： Bombycidae） exhibits a maternally controlled embryonic diapause. Maternal silkworms decide whether to lay diapause or nondiapause eggs depending on environmental factors such as the temperature and photoperiod during the egg and larval stages, and then induce diapause eggs during the pupal stage. However, little is known about the molecular mechanism that conveys the outcome of whether to produce diapause or nondiapause eggs from the egg or larval stages to the pupal stage. This study used microarray analysis to investigate differentially expressed genes in the larval brains of diapause- and nondiapause-egg producers, to which bivoltine silkworms were destined by thermal or photic stimulation during the egg stage. The cytochrome P450 18al and Kriippel homolog i genes were upregulated in producers of diapause eggs compared with those of nondiapause eggs under both experimental conditions. Cytochrome P450 18al encodes a key enzyme for steroid hormone inactivation and Krfippel homolog 1 is an early juvenile hormone-inducible gene that mediates the repression of metamorphosis. The upregulation of these genes during the larval stage might be involved in the signaling pathway that transmits information about the diapause program from the egg stage to the pupal stage in the silkworm.

关键词： cytochrome P450 18a l Kriippel homolog 1 silkworm

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Implementing a vector surveillanceresponse system for chagas disease control:a 4-year field trial in Nicaragua

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Infectious Diseases of Poverty 2017年第1期6卷 154-165页

作者： Kota Yoshioka Doribel Tercero Byron Perez Jiro nakamura Lenin Perez Doctor of Public Health Program Harvard T.H.Chan School of Public HealthBostonUSA School of Tropical Medicine and Global Health Nagasaki UniversityNagasakiJapan Former Chagas Disease Control Project Japan International Cooperation AgencyManaguaNicaragua Department of Disease Prevention Ministry of Health in NicaraguaManaguaNicaragua

Background:Chagas disease is one of the neglected tropical diseases(NTDs).International goals for its control involve elimination of vector-borne *** American countries face challenges in establishing sustainable vector control programmes,since the main vector,Triatoma dimidiata,cannot be *** 2012,the Ministry of Health in Nicaragua started a field test of a vector surveillance-response system to control domestic vector *** paper reports the main findings from this pilot ***:This study was carried out from 2012 to 2015 in the Municipality of *** Japan International Cooperation Agency provided technical cooperation in designing and monitoring the surveillance-response system until *** system involved 1)vector reports by householders to health facilities,2)data analysis and planning of responses at the municipal health centre and 3)house visits or insecticide spraying by health personnel as a *** registered all vector reports and responses in a digital *** collected data were used to describe and analyse the system performance in terms of amount of vector reports as well as rates and timeliness of ***:During the study period,*** was reported 396 *** analysis identified some high-risk *** houses reported to be infested were visited by health personnel in 2013 and this response rate dropped to 39%in *** of insecticide spraying rose above 80%in 2013 but no spraying was carried out in the following 2 *** timeliness of house visits improved significantly after the responsibility was transferred from a vector control technician to primary health care ***:We argue that the proposed vector surveillance-response system is workable within the resourceconstrained health system in *** to the primary health care services was a key to improve the system *** efforts are necessary to keep adap

关键词： Chagas disease Triatoma dimidiata Vector control Surveillance-response system Programme integration Nicaragua

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Morphology and gene expression of sex‐determining region Y‐box 9 and runt‐related transcription factor 2 in centrifugally compressed cell collagen‐combined constructs (C^(6))

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Biosurface and Biotribology 2023年第3期9卷 78-83页

作者： Xu Ye Masashi Yamazaki Wataru Ando Norimasa nakamura Hiromichi Fujie Faculty of System Design Tokyo Metropolitan UniversityTokyoJapan Research Center for Medicine‐Engineering Collaboration TokyoJapan Department of Orthopaedic Surgery Kansai Rosai HospitalAmagasakiJapan Department of Orthopaedic Surgery Osaka University Graduate School of MedicineSuitaJapan Institute for Medical Science in Sports Osaka Health Science UniversityOsakaJapan Center for Advanced Medical Engineering and Informatics Osaka UniversitySuitaJapan

The authors previously developed a scaffold‐free tissue‐engineered construct(TEC)from mesenchymal stem cells(MSCs).Although the TEC exhibited even cell distribution and was successfully applied for cartilage repair in animal models,it is unsuitable for relatively large‐scale cartilage defects due to its small *** solve the problem,the authors recently developed a novel biomaterial,a centrifugally compressed cell‐collagen combined construct(C^(6))from a mixture of MSCs and atelocollagen,both of which are subjected to *** results of the previous study indicated that C^(6) exhibited high cell viability(70%)and sufficient cell distribution similar to that of the *** the present study,the morphology and gene expression of C^(6) were *** ex-amination indicated that C6 is six times thicker(approximately 1 mm)than the TEC after a 7‐day *** C^(6) remained unchanged in scale with increased cell density after a 21‐day *** electron microscopic observation indicated that C^(6) exhibited interconnected and porous microstructures,while the TEC had close‐knit *** transcriptase‐polymerase chain reaction analysis indicated that the expression of sex‐determining region Y‐box 9 and runt‐related transcription factor 2 was significantly higher in C^(6) than that in TEC.

关键词： biomaterials cartilage microstructures

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