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Gracilis Muscular Flap for Large Urethral Defect

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Surgical Science 2011年第9期2卷 456-458页

作者： Yuichiro Yoshioka Shigeaki Moriura Hiroshi Yuba atsushi hirano Ryohei Hattori 不详

We report the use of Gracilis muscle to repair a large urethral defect. A 57-year-old-man with rectal cancer underwent abdominoperineal resection including part of the prostate and seminal vesicle. Soon after surgery, he presented with massive urinary leakage from the prostatic urethra. Conservative treatment for one month failed. The defect of the prostatic urethra, measuring 2.5 cm in diameter, was closed with the right gracilis muscular flap. About five years and 6 months after surgery, the patient can void spontaneously without incontinence. Cystoscopy demonstrated good epithelization of the reconstructed urethra without stenosis. The gracilis muscular flap was easily available and useful for closure of a large urethral defect.

关键词： Urethral Injury Reconstruction

Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations

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World Journal of Gastroenterology 2019年第14期25卷 1753-1763页

作者： Yuichi Matsuno Junji Umeno Motohiro Esaki Yoichiro Hirakawa Yuta Fuyuno Yasuharu Okamoto atsushi hirano Shigeyoshi Yasukawa Fumihito Hirai Toshiyuki Matsui Shuhei Hosomi Kenji Watanabe Naoki Hosoe Haruhiko Ogata Tadakazu Hisamatsu Shunichi Yanai Shuji Kochi Koichi Kurahara Tsuneyoshi Yao Takehiro Torisu Takanari Kitazono Takayuki Matsumoto Department of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Department of Endoscopic Diagnostics and Therapeutic Saga University Hospital Department of Epidemiology and Public Health Graduate School of Medical Sciences Kyushu University Department of Gastroenterology Fukuoka University Chikushi Hospital Department of Gastroenterology Osaka City University Graduate School of Medicine Department of Intestinal Inflammation Research Hyogo College of Medicine Center for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University the Third Department of Internal Medicine Kyorin University School of Medicine Division of Gastroenterology Department of Internal Medicine Iwate Medical University Division of Gastroenterology Matsuyama Red Cross Hospital Department of Gastroenterology Sada Hospital

BACKGROUND We recently reported on a hereditary enteropathy associated with a gene encoding a prostaglandin transporter and referred to as chronic enteropathy associated with SLCO2 A1 gene(CEAS). Crohn's disease(CD) is a major differential diagnosis of CEAS, because these diseases share some clinical features. Therefore, there is a need to develop a convenient screening test to distinguish CEAS from *** To examine whether prostaglandin E major urinary metabolites(PGE-MUM) can serve as a biomarker to distinguish CEAS from *** This was a transactional study of 20 patients with CEAS and 98 patients with *** was diagnosed by the confirmation of homozygous or compound heterozygous mutation of SLCO2 A1. We measured the concentration of PGEMUM in spot urine by radioimmunoassay, and the concentration was compared between the two groups of patients. We also determined the optimal cut-off value of PGE-MUM to distinguish CEAS from CD by receiver operating characteristic(ROC) curve *** Twenty Japanese patients with CEAS and 98 patients with CD were ***-MUM concentration in patients with CEAS was significantly higher than that in patients with CD(median 102.7 vs 27.9 μg/g × Cre, P < 0.0001). One log unit increase in PGE-MUM contributed to 7.3 increase in the likelihood for the diagnosis of CEAS [95% confidence interval(CI) 3.2-16.7]. A logistic regression analysis revealed that the association was significant even after adjusting confounding factors(adjusted odds ratio 29.6, 95%CI 4.7-185.7). ROC curve analysis revealed the optimal PGE-MUM cut-off value for the distinction of CEAS from CD to be 48.9 μg/g × Cre with 95.0% sensitivity and 79.6% *** PGE-MUM measurement is a convenient, non-invasive and useful test for the distinction of CEAS from CD.

关键词： Chronic enteropathy associated with SLCO2A1 gene Prostaglandin E major urinary metabolites Chronic nonspecific multiple ulcers of the small intestine Crohn's disease Small intestine

Gracilis Muscular Flap for Large Urethral Defect

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JSAE-SICE benchmark problem for vehicle dynamics control

Surgical Science（外科学） 2011年第9期

作者： Yuichiro Yoshioka Shigeaki Moriura Hiroshi Yuba atsushi hirano Ryohei Hattori

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Control Theory and Technology 2019年第2期17卷 131-137页

作者： Yutaka hirano Toyota Motor Corporation 1200MishukuSusonoShizuoka410-1193Japan

Recently many new types of small vehicles for future urban societies have been proposed and *** small vehicles tends to have reduced stability and handling ability than conventional vehicles because of their lighter weight and reduced tire *** cope with this problem by active collaboration of Japanese academia and industries,a benchmark problem of designing vehicle control logic for an articulated In-Wheel-Motor vehicle was settled by Japanese society of automotive industries and *** this purpose,simulation models of the new vehicle using multi-physics acausal modeling language Modelica were provided from the industry *** were requested to design controllers of tire steering angle,tire camber angle and tire driving force to satisfy requested vehicle dynamic *** also were some restrictions about the range of *** test scenarios were given to evaluate the control *** challengers from Japanese Universities have tackled with this benchmark *** results of their researches are also introduced in this paper.

关键词： Automotive control vehicle dynamics future mobility stability and handling performance modeling and simulation Modelica

Atomistics of superlubricity

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Friction 2014年第2期2卷 95-105页

作者： Motohisa hirano Department of Mechanical Engineering Faculty of Science and Engineering Hosei University 3-7-2 KajinoKoganei184-8584 Tokyo

Friction is a phenomenon observed ubiquitously in daily life,yet its nature is *** between rough surfaces is considered to arise primarily because of macroscopic *** contrast,interatomic forces dominate between clean and smooth surfaces.“Superlubricity”,where friction effectively becomes zero,occurs when the ratio of lattice parameters in the pair of surfaces becomes an irrational *** has been found to exist in a limited number of systems,but is a very important phenomenon both in industry and in mechanical *** atomistic research on friction is under way,with the aim of refining theoretical models that consider interactions between atoms beyond mean field theory and experiments using ultrahigh vacuum non-contact atomic force *** research is expected to help clarify the nature of microscopic friction,reveal the onset conditions of friction and superlubricity as well as the stability of superlubricity,discover new superlubric systems,and lead to new applications.

关键词： atomic-level friction atomistics of friction nanotribology superlubricity

Prototyping of Ultra Micro Centrifugal Compressor-Influence of Meridional Configuration

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Journal of Thermal Science 2011年第4期20卷 312-317页

作者： Toshiyuki hirano Tadataka Muto Hoshio Tsujita Production Systems Engineering Course Tokyo Metropolitan College of Industrial Technology Graduate School of Engineering Hosei University3-7-2KajinochoKoganei-shiTokyo184-8584Japan Department of Mechanical Engineering Faculty of Science and EngineeringHosei University

In order to investigate the design method for a micro centrifugal compressor, which is the most important component of an ultra micro gas turbine, two types of centrifugal impeller with 2-dimensional blade were designed, manufactured and tested. These impellers have different shapes of hub on the meridional plane with each other. Moreover, these types of impeller were made for the 5 times and the 6 times size of the final target centrifugal impeller with the outer diameter of 4ram in order to assess the similitude for the impellers. The comparison among the performance characteristics of the impellers revealed the influence of the meridional configuration on the performance and the similitude of the compressors.

关键词： Ultra Micro Centrifugal Compressor Performance Characteristics Impeller Meridional Configuration

Effect of Double Air Injection on Performance Characteristics of Centrifugal Compressor

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Journal of Thermal Science 2015年第1期24卷 10-16页

作者： Toshiyuki hirano Mizuki Takano Hoshio Tsujita Mechanical Engineering Course Department of Science and Engineering Kokushikan University Advanced Course of Mechanical Engineering Program Tokyo Metropolitan College of Industrial Technology 10-40Higashi-oi 1-chome Shinagawa CityTokyo 140-0011 Tokyo Japan Department of Mechanical Engineering Faculty of Science and Engineering Hosei University

In the operation of a centrifugal compressor of turbocharger, instability phenomena such as rotating stall and surge are induced at a lower flow rate close to the maximum pressure ratio. In this study, for the suppression of surge phenomenon resulting in the extension of the stable operating range of centrifugal compressor to lower flow rate, the compressed air at the compressor exit was re-circulated and injected into the impeller inlet by using the double injection nozzle system. The experiments were performed to find out the optimum circumferential position of the second nozzle relative to the fixed first one and the optimum inner diameter of the injection nozzles, which are able to most effectively reduce the flow rate of surge inception. Moreover, in order to examine the universality of these optimum values, the experiments were carried out for two types of compressors.

关键词： Centrifugal Compressor Performance Nozzle Injection Surge

Numerical Analysis of Flow in Ultra Micro Centrifugal Compressor -Influence of Meridional Configuration

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Journal of Thermal Science 2013年第2期22卷 111-116页

作者： Masanao Kaneko Hoshio Tsujita Toshiyuki hirano Graduate School of Engineering Hosei University Department of Mechanical Engineering Faculty of Science and EngineeringHosei University Production Systems Engineering Course Tokyo Metropolitan College of Industrial Technology

A single stage ultra micro centrifugal compressor constituting ultra micro gas turbine is required to operate at high rotational speed in order to achieve the pressure ratio which establishes the gas turbine cycle. As a conse- quence, the aerodynamic losses can be increased by the interaction of a shock wave with the boundary layer on the blade surface. Moreover, the centrifugal force which exceeds the allowable s^ress of the impeller material can act on the root of blades. On the other hand, the restrictions of processing technology for the downsizing of im- peller not only relatively enlarge the size of tip clearance but also make it difficult to shape the impeller with the i three-dimensional blade. Therefore, it is important to establish the design technology for the impeller with the two-dimensional blade which possesses the sufficient aerodynamic performance and enough strength to bear the centrifugal force caused by the high rotational speed. In this study, the flow in two types of impeller with the two-dimensional blade which have different meridional configuration was analyzed numerically, The computed results clarified the influence of the meridional configuration on the loss generations in the impeller passage.

关键词： Ultra Micro Centrifugal Compressor Two-dimensional Blade Gas Turbine Numerical Analysis

Advances in diagnostic testing for gastroesophageal reflux disease

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World Journal of Gastroenterology 2010年第30期16卷 3750-3756页

作者： Andrew J Gawron Ikuo hirano Division of Gastroenterology Department of MedicineNorthwestern University Feinberg School of MedicineChicagoIL 60611-2951United States

Gastroesophageal reflux disease (GERD) contributes substantially to morbidity and to costs in the United States health care system. The burden of this disease has resulted in attempts at improving diagnosis and characterizing patients. Numerous research and technical advances have enhanced our understanding of both the utility and limitations of a variety of diagnostic modalities. The purpose of this review is to highlight recent advances in GERD diagnostic testing and to discuss their implications for use in clinical practice. Topics addressed include esophageal pH monitoring, impedance testing, symptom association analyses, narrow-band imaging, and histopathology.

关键词： Gastroesophageal reflux disease pH impedance pH monitoring Symptom association