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Antiprotozoal assessment and phenolic acid profiling of five Fumaria(fumitory) species

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Asian Pacific Journal of Tropical Medicine 2015年第4期8卷 283-286页

作者： Ilkay Erdogan Orhan nilgun ozturk Bilge Sener Department of Pharmacognosy Faculty of PharmacyGazi University Department of Pharmacognosy Faculty of PharmacyAnadolu University

Objective:To explore some Fumaria species which were recorded to be traditionally used against malaria and other protozoal ***:Consequently,in the current study,antiprotozoal effect of the ethanol extracts obtained from five Fumaria species(Fumaria densiflora,Fumaria cilicica,Fumaria rostellata,Fumaria kralikii,and Fumaria parviflora)was investigated against the parasites;Plasmodium falciparum(malaria)and Trypanosoma bruceirhodesiense(human African trypanosomiasis)at 0.81 and 4.85μg/mL ***:Among them,Fumaria densiflora extract exerted the highest antiplasmodial(93.80%)and antitrypanasomal effect(55.40%),while the ethanol extracts of Fumaria kralikii(43.45%)and Fumaria rostellata(41.65%)showed moderate activity against Plasmodium ***,phenolic acid contents of the extracts were analyzed using high performance liquid chromatography(HPLC)and trans-cinnamic(4.32 mg/g)and caffeic(3.71 mg/g)acids were found to be the dominant phenolic acids in Fumaria ***:According to our results,Fumaria densiflora deserve further study for its promising antiprotozoal activity.

关键词： Fumaria Fumitory Antiprotozoal Malaria Trypanosomiasis Phenolic acid

The Effect of Storage Solutions on Mineral Content of Enamel

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Materials Sciences and Applications 2013年第7期4卷 439-445页

作者： Asli Secilmis Erhan Dilber nilgun ozturk Fatma Gokmen Yilmaz Department of Prosthodontics Faculty of DentistryUniversity of GaziantepGaziantepTurkey Department of Prosthodontics Faculty of DentistrySifa UniversityİzmirTurkey Department of Prosthodontics Faculty of DentistryUniversity of SelcukKonyaTurkey Department of Soil Science Faculty of AgriculturalUniversity of SelcukKonyaTurkey

Purpose: This study evaluated the influence of different storage times and storage solutions on the mineral content of enamel. Methods: Ninety enamel slabs were randomly divided into 2 groups of 45: a 45-day group and a 90-day group. Each of these main groups was further subdivided into 9 experimental groups of 5 slabs, and each subgroup was stored in a different storage solution. The mean percentage weights of 5 elements (calcium, potassium, sodium, phosphorus, and magnesium) presented in each enamel slab was measured after storage using inductively coupled plasmaatomic emission spectrometry. Two-way analysis of variance (ANOVA) and Turkey’s honestly significant difference tests were used to analyze differences between the groups. Results: Storage conditions significantly affected the levels of calcium, potassium, sodium, and phosphorus (p 0.05). Storage procedures can significantly affect the calcium, potassium, sodium, and phosphorus contents of enamel.

关键词： Storage Solution Storage Time Enamel ICP-AES Mineral Content

ANALGESIC ACTIVITY OF HAWTHORN SEED EXTRACT

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ANALGESIC ACTIVITY OF HAWTHORN SEED EXTRACT

The Effects of Porcelain Polishing Techniques on the Color and Surface Texture of Different Porcelain Systems

第十五届国际药理学大会

作者： Can Ozgur Demir Umide ozturk nilgun ozturk Yusuf Anadolu Unv Plant Drag and Scientific Research Centre 26470 EskisehirTURKEY. Anadolu Univ.Fac.Pharmacy Dept.Pharmacology 26470 Eskisehir TURKEY. Anadolu Univ.Fac.Pharmacy Dept.O Pharmacognosy 26470 Eskisehir TURKEY. Anadolu Univ.Fac.Pharmacy Dept.Pharmacology 26470 Eskisehir TURKEY.

＜正＞ Hawthorn （Crataegus monogyna, Rosaceae） extracts are among the most popular herbal medicinal products in the U. S. A. and various European countries. Hawthorn has been used for its several pharmacological effects more than 700 years as a folk medicine. Although various pharmacological activities of Hawthorn have been reported previously,to the best of our knowledge,there have been no reports related to its analgesic action. Here we aimed to investigate the analgesic activity of plant seed extract. Analgesic activity of morphine （2 mg/kg） and the extract （1 - 1000 mg/kg） were measured by tail - clip and tail - immersion tests. Naloxone （5 mg/kg） was used as opioid antagonist. In tail clip tests. 10 - 1000 mg/kg doses of the extract showed analgesic activity,whereas its 1mg/ kg dose did not. Naloxone antagonized its analgesic effect. No analgesic activity was observed in tailimmersion test. LD50 value of the extract was estimated higher than 1000 mg/ kg. Being important for the development of new analgesic drugs,this is the first report for the analgesic activity of Hawthorn seeds possibly due to endogenous opioid system. However,further studies are necessary.

关键词： Hawthorn Crataegus analgesia

来源： cnki会议评论

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Materials Sciences and Applications 2012年第5期3卷 294-300页

作者： Ali Riza Tuncdemir Erhan Dilber Haluk Baris Kara A.nilgun ozturk Department of Prosthodontics Mustafa Kemal UniversityAntakyaTurkey Department of Prosthodontics Faculty of DentistrySelçuk UniversityKonyaTurkey Department of Prosthodontics Medipol UniversityIstanbulTurkey

The aim of this study was to compare the effects of different porcelain polishing techniques on the color change and surface roughness of feldspathic porcelains and lithium disilicate glass-ceramic system. 80 porcelain specimens were divided into two subgroups, each subgroup was divided into 4 groups of 10 specimens. Surfaces were polished with different ceramic polishers. VITA Easyshade spectrophotometer was used to measure color differences. Surface roughness was evaluated using a profilometer. The color change and surface roughness of porcelains were statistically analyzed by Two-way ANOVA followed by a Tukey HSD test (α = 05). There were relationships between the porcelain systems and polishing techniques (p 0.05). For △E values, there was relationship between the porcelain systems and polishing techniques (p 0.05). Chairside porcelain polishing systems were not able to provide a porcelain surface as smooth as the glazed surface for the IPS empress and Ceramco 3 porcelains.

关键词： Color Glaze Polish Porcelain Surface Roughness