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Prevalence of celiac disease in Germany:A prospective follow-up study

World Journal of Gastroenterology 2013年第17期19卷 2612-2620页

作者： Wolfgang Kratzer Monika Kibele atilla akinli Marc Porzner Bernhard O Boehm Wolfgang Koenig Suemeyra Oeztuerk Richard A Mason Ren Mao Mark H Haenle Department of Internal Medicine Ⅰ University Hospital Ulm Department of Internal Medicine Ⅱ University Hospital Ulm Louis Stokes Cleveland Department of Veterans Affairs Medical Center Department of Gastroenterology the First Affiliated Hospital of Sun Yat-sen University

AIM:To determine the prevalence of celiac disease in a randomly selected population sample. METHODS:A total of 2157 subjects (1036 males; 1121 females) participating in a population-based cross-sectional study underwent laboratory testing for tissue transglutaminase and antibodies to immunoglobulin A, endomysium and antigliadin. In a second step, all subjects who had been examined serologically were surveyed using a questionnaire that included questions specific to celiac disease. Subjects with positive antibody titers and those with histories positive for celiac disease then underwent biopsy. At the first follow up, antibody titers were again determined in these subjects and subjects were questioned regarding symptoms specific for celiac disease and disorders associated with celiac disease. The second follow up consisted of a telephone interview with subjects positive for celiac ***:Antibody tests consistent with celiac disease were reported in eight subjects, corresponding to an overall prevalence of 1:270 (8/2157). The prevalence among women was 1:224 and 1:518 in men. Classical symptoms were observed in 62.5% of subjects. Atypical celiac disease was present in 25.0%, and transient celiac disease in 12.5%. False-negative test results were returned in three subjects. This yields a sensitivity and specificity of 62.5% and 50.0%, respectively, for tissue transglutaminase immunoglobulin-A antibody; of 62.5% and 71.4% respectively, for endomysium antibody; and of 62.5% and 71.4%, respectively, for antigliadin ***:The prevalence rate in our collective lies within the middle tertile of comparable studies in Europe. The use of a single antibody test for screening purposes must be called into question.

关键词： Cross-sectional study Celiac disease Screening Prevalence Serology

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Determination of characteristics for mechanically separated organic fraction of MsW at a full-scale anaerobic digestion plant

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Waste Disposal and Sustainable Energy 2024年第2期6卷 233-241页

作者： Yagmur Kabakci Sadiye Kosar Ozgur Dogan Fehmi Gorkem Uctug Osman atilla Arikan Department of Environmental Engineering Istanbul Technical University34469 AyazagaIstanbulTurkiye TUBITAK Marmara Research Center 41400 GebzeKocaeliTirkiye Centre for Water Technology(WATEC)and Department of Biological and Chemical Engineering Aarhus UniversityOle Worms Allé38000 Aarhus CDenmark Faculty of Engineering Izmir University of Economics35330BalcovaIzmirTurkiye

Anaerobic digestion(AD)as a waste management method has the potential to reduce greenhouse gas emissions while pro-ducing renewable energy,making it a viable option for managing the organic fraction of municipal solid waste(OFMSW).OFMSW characteristics can vary depending on factors such as waste source,composition and separation *** charac-teristics of OFMSW are critical for analyzing and monitoring the AD process to optimize biogas *** this study,the waste composition and physicochemical characteristics of the mechanically separated OFMSW(ms-OFMSW)were determined at a full-scale AD plant in *** ms-OFMSW samples were collected monthly after mechanical separation and were subsequently sent to the anaerobic *** composition and physicochemical characteristics of the samples were determined by manual *** results showed that the majority of the ms-OFMSW(76.45%±1.71%)was organic,while 8.99%±1.56%was recyclable and 14.56%±1.69%was *** of environmental benefits for the recyclable materials was determined using a free online tool provided by Environmental Protection ***(399.7 GJ)and plas-tics(403.7 GJ)both saved nearly the same amount of energy while metals saved the most water(421.8 m3),with the greatest positive *** benefits ranged from 3 tons to 40 tons of carbon dioxide equivalent for each waste *** findings suggest that efficient pre-separation units can improve the anaerobic digestibility of OFMSW,while also providing greater environmental benefits by preventing recyclable waste from the anaerobic *** addition to encouraging source separation applications,this study demonstrates the need for improved technologies to separate OFMSW from mixed MSW.

关键词： Anaerobic digestion Composition Mechanical separation Organic fraction of municipal solid waste Ms-OFMSW

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An evaluation of ureteral diameter ratio and vesicoureteral reflux index in the treatment of primary vesicoureteral reflux

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Asian Journal of Urology 2024年第3期11卷 437-442页

作者： Yusuf Atakan Baltrak Nebil Akdogan Mutlu Deger Volkan Izol Ibrahim atilla Aridogan Nihat Satar Division Pediatric Urology Department of UrologyMedical FacultyCukurova UniversityAdanaTurkey

Objective:Vesicoureteral reflux(VUR)index is a simple,validated tool that reliably predicts significant improvement and spontaneous resolution of primary reflux in *** aim of this study was to evaluate and compare the ureter diameter ratio(UDR)and VUR index(VURx)of patients treated with endoscopic injection(EI)and ureteroneocystostomy(UNC)methods in the pediatric age group due to primary ***:Patients under the age of 18 years old who underwent EI and UNC with the diagnosis of primary VUR between January 2011 and September 2021 were determined as the *** UDR was assessed using voiding cystourethrography,and the VURx score was determined prior to treatment based on hospital records included in the ***:A total of 255 patients,60(23.5%)boys and 195(76.5%)girls,with a mean age of 76.5(range 13.0e204.0)months,were included in the *** was applied to 130(51.0%)patients and UNC was applied to 125(49.0%)patients due to primary *** optimum cut-off for the distal UDR was obtained as 0.17 with sensitivity and specificity of 73.0%and 63.0%,*** positive and negative predictive values were 66.0%and 70.0%,***:When the UDR and VURx score are evaluated together for the surgical treatment of primary VUR in the pediatric age group,it is thought that it may be useful in predicting the clinical course of the disease and evaluating surgical treatment options.

关键词： Distalureter diameter ratio Vesicoureteral reflux Vesicoureteral reflux index management Vesicoureteral reflux index

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不同装载条件下小型渔船参数横摇的非定常RANS CFD仿真

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哈尔滨工程大学学报（英文版） 2024年第2期23卷 327-351页

作者： Muhammad Iqbal Momchil Terziev Tahsin Tezdogan atilla Incecik Department of Naval Architecture Oceanand Marine EngineeringUniversity of StrathclydeGlasgow-G40LZUK Department of Naval Architecture Diponegoro UniversitySemarang-50275Indonesia Department of Civil Maritime and Environmental EngineeringUniversity of SouthamptonSouthampton-SO167QFUK

Fishing boats have unique features that make them prone to changing loading *** the boat leaves the port,the empty fish tank gradually fills up during fishing operations which may result in parametric roll(PR).This dangerous phenomenon that can lead to *** present study aims to understand better the behaviour of parametric roll in fishing boats and its relation to changing loading *** study considers the effects of displacement and the GM/KM ratio on parametric roll,as well as the longitudinal flare distribution at the *** assessments to detect the parametric roll occurrence in early stage were carried out by using the level 1 assessment of parametric roll based on the Second Generation of Intact Stability criteria(SGIS)from International maritime Organisation(IMO)and the Susceptibility criteria of Parametric roll from the American Bureau of Shipping(ABS).Then,the CFD method is used to predict the amplitude of the parametric roll *** results provide important insights to fishing vessel operators on how to manage loading conditions to maintain stability and avoid hazardous *** following the guidelines outlined in this study,fishing boats can operate more safely and efficiently,reducing the risk of accidents and improving the overall sustainability of the fishing industry.

关键词： Small fishing boat Parametric roll URANS-CFD KRISO Container Ship(KCS) Stability in waves

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Risk Factors in Surgical Site Infections

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Surgical Science 2024年第2期15卷 64-80页

作者： atilla Duran Hüseyin Gülay Mustafa Cem Terzi Department of General Surgery Mersin City Training and Research Hospital Mersin Türkiye Department of General Surgery Baskent University Ankara Türkiye Department of General Surgery Acibadem Kent Hastanesi Izmir Türkiye

Purpose of the Research: Our study aimed to determine and understand the risk factors of surgical site infections in patients operated on in general surgery wards. Method of Research: Between May 2008 and November 2008, 422 consecutive patients who underwent emergency and elective surgeries, excluding breast, goitre and laparoscopic surgeries, were included in the study to determine surgical site infections and risk factors. The patients’ risk factors were selected in the preoperative period, and postoperative 3rd, 7th, and 30th days were checked by the physician responsible for conducting the study regarding surgical site infection. Results and Conclusion: Surgical site infections were defined as incisional and organ/space based on NNIS data. Gender, diabetes mellitus, malignancy, degree of contamination, ASA score ≥ 3, preoperative skin cleansing, duration of intensive care unit stay, duration of hospital stay, growth in wound culture, duration of surgery and incision length were determined as risk factors increasing CAI rates. Especially the degree of contamination, duration of intensive care unit stay, hospitalisation, duration of operation, and growth in wound culture were decisive factors in the development of CAI. As a result of our study, in the light of these data, we concluded that to prevent the development of CAI can be modified, interventions to foreseeable factors can be assessed.

关键词： Infection CAI Risk Patient

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Trajectory Tracking of a Planer Parallel Manipulator by Using Computed Force Control Method

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Chinese Journal of Mechanical Engineering 2017年第2期30卷 449-458页

作者： atilla BAYRAM Department of Mechanical Engineering Yuzuncu YilUniversityVanTurkey

Despite small workspace, parallel manipulators have some advantages over their serial counterparts in terms of higher speed, acceleration, rigidity, accuracy, manufacturing cost and payload. Accordingly, this type of manipulators can be used in many applications such as in high-speed machine tools, tuning machine for feeding, sensitive cutting, assembly and packaging. This paper presents a special type of planar parallel manipulator with three degrees of freedom. It is constructed as a variable geometry truss generally known planar Stewart platform. The reachable and orientation workspaces are obtained for this manipulator. The inverse kinematic analysis is solved for the trajectory tracking according to the redundancy and joint limit avoidance. Then, the dynamics model of the manipulator is established by using Virtual Work method. The simulations are performed to follow the given planar trajectories by using the dynamic equations of the variable geometry truss manipulator and computed force control method. In computed force control method, the feedback gain matrices for PD control are tuned with fixed matrices by trail end error and variable ones by means of optimization with genetic algorithm.

关键词： Parallel manipulator Variable geometry truss manipulator Planar Stewart platform. Dynamic analysis Computed force control Genetic algorithm

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Posterior vitreous detachment rate following intravitreal dexamethasone injection

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International Journal of Ophthalmology(English edition) 2019年第8期12卷 1298-1303页

作者： atilla Alpay Department of Ophthalmology the School of MedicineZonguldak Bülent Ecevit University

AIM: To determine whether intravitreal dexamethasone(DEX) implant induces posterior vitreous detachment or not. METHODS: We retrospectively reviewed 810 eyes of 405 patients who underwent intravitreal DEX implantation due to macular edema caused by diabetic and retinal venous occlusion in our clinic. The eyes having no injection were determined as the control group. The examination findings of the patients before the injection and 3 mo after the injection and optical coherence tomography(OCT) images were scanned. The pre-injection OCT findings and OCT findings of the patients having no posterior vitreous detachment(PVD) and determined to have partial PVD were compared. RESULTS: The separation in vitreoretinal adhesion and total PVD development of DEX-injected 56/208(26.9%) eyes were statistically greater in comparison with the 12/129(9.3%) eyes that had not been injected(P=0.001). PVD development was observed more in the patients that were younger, had larger macula thickness and lower visual acuity. CONCLUSION: It can be stated that intravitreal DEX implant induces PVD development. Prospective, controlled studies are required in order to determine prognosis of vitreoretinal disease in PVD-developed patients and in non-PVD-developed patients.

关键词： dexamethasone implant intravitreal injection vitreoretinal adhesion diabetic macular edema retinal vein occlusion posterior vitreous detchment

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Investigation of the effects of platform motion on the aerodynamics of a floating offshore wind turbine

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Journal of Hydrodynamics 2016年第1期28卷 95-101页

作者： Yuanchuan LIU Qing XIAO atilla INCECIK 万德成 Department of Naval Architecture Ocean and Marine Engineering University of Strathclyde State Key Laboratory of Ocean Engineering School of Naval Architecture Ocean and Civil EngineeringShanghai Jiao Tong University

Along with the flourishing of the wind energy industry, floating offshore wind turbines have aroused much interest among the academia as well as enterprises. In this paper, the effects of the supporting platform motion on the aerodynamics of a floating wind turbine are studied using the open source CFD framework Open FOAM. The platform motion responses, including surge, heave and pitch, are superimposed onto the rotation of the wind turbine. Thrust and torque on the wind turbine are compared and analysed for the cases of different platform motion patterns together with the flow field. It is shown that the movement of the supporting platform can have large influences on a floating offshore wind turbine and thus needs to be considered carefully during the design process.

关键词： floating offshore wind turbine superimposed platform motion aerodynamics Open FOAM

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Longwall top coal caving design for thick coal seam in very poor strength surrounding strata

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International Journal of Coal Science & Technology 2021年第4期8卷 641-658页

作者： H.Jangara C.atilla Ozturk Mining Engineering Department Faculty of MinesIstanbul Technical UniversityIstanbulTurkey

Alpu lignite field is an important coal deposit with nearly 2 billion tons of coal resources located in the middle of *** mine deposit consists of three main *** thickness of two of them vary from 4 to 30 *** surrounding rock mass is very poor in terms of *** high clay content and weak rock mass make mechanized mining *** this research,applicability of the longwall top coal caving method was *** very weak strength behavior of the coal and the surrounding strata increases the importance of research in the mine site in terms of ground *** aim is to design the mechanized longwall mine based on ground control *** of all,classification of the roof,coal,inter-burden,and floor strata were classified based on geotechnical ***,cavability index,shield,and floor bearing capacity were *** methods were applied to understand the limitations of a mechanized system that is very critical due to the very low strength *** to the main results,roof strata was classified as immediately caving while mining height was calculated as 5-6 ***,the relations among geotechnical characterizations of roof and floor strata,cutting and caving heights,and required shield capacity were presented based on analytical and numerical *** proposed approach can be used as a ground control method for the applicability as well as the limitations of mechanized longwall mining design in weak strata conditions.

关键词： Coal Geotechnics Ground control Longwall mining Numerical methods

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A broker-based semantic agent for discovering Semantic Web services through process similarity matching and equivalence considering quality of service

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Science China(Information Sciences) 2013年第1期56卷 18-41页

作者： ELK Duygu EL atilla Computer Engineering Department Istanbul Aydin University Electrical-Elecronics Engineering Department Aksaray University

The lack of semantic descriptions for "web service properties" makes it difficult to find suitable web *** solutions are mostly based on broker/mediator agent ***,these techniques are syntactical,rather than semantics *** article presents a semantic matching approach for discovering Semantic Web services through a broker-based semantic agent(BSA).The BSA includes knowledge-bases and several processing *** BSA’s knowledge-bases are concept,task,and process ontologies built to describe both functional and non-functional parameters of *** BSA executes semantic-based matching algorithms to discover similar services through the semantic matching step,process equivalence task,and matching of quality of service *** services are ranked by client preferences utilizing the semantic descriptions of available *** matchmaker studies are reviewed and compared with the *** of the BSA algorithm is compared with SAM using published data and an experimental *** results indicate that our approach is better and more effective in some respects.

关键词： Semantic Web Semantic Web services broker web applications ontologies semantic agents

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