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Colorectal cancer screening: Modalities and adherence

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World Journal of Gastroenterology 2024年第24期30卷 3048-3051页

作者： Georgios Metaxas athena Papachristou Martha Stathaki Department of Surgery Elena Venizelou HospitalAthens 11521Greece

In the last decade,several studies have explored various modalities and strategies for colorectal cancer(CRC)screening,taking into account epidemiological data,individual characteristics,and socioeconomic *** this editorial,we comment further on a retrospective study by Agatsuma et al published in the recent issue of the World Journal of *** focus is on screening trends,particularly in relation to efforts to improve the currently suboptimal uptake among the general population worldwide,aiming to enhance early diagnosis rates of *** is a need to raise awareness through health edu-cation programs and to consider the use of readily available,non-invasive screening *** strategies are crucial for attracting screen-eligible populations to participate in first-line screening,especially those in high-or average-risk groups and in regions with limited *** biopsies and biomarkers represent rapidly evolving trends in screening and diagnosis;however,their clinical relevance has yet to be standardized.

关键词： Colorectal cancer Screening test High-risk group Strategies Biomarker Liquid biopsy Screening adherence

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城市环境设计 2019年第2期118卷 84-99页

作者： H?gni Laksáfoss Alberte Danvig Alejandro Mata Gonzales Alessio Valmori Alexandre Carpentier Annette Birthe Jensen Armen Menendian athena morella Baptiste Blot Boris Peianov Camille Crepin Claudio Moretti Dag Pr?stegaard Daniel Pihl David Zahle Edouard Boisse Elisha Nathoo Enea Michelesio Eskild Nordbud Ewelina Moszczynska Frederik Lyng Goda Luksaite Henrik Kania H?gni Laksáfoss Jakob Lange Jakob Teglg?rd Hansen Jan Besikov Jan Kudlicka Jan Magasanik Jeppe Ecklon Jesper Boye Andersen Ji-Young Yoon Johan Cool Kari-Ann Petersen Kim Christensen Kristoffer Negendahl Long Zuo Martin Cajade Michael Sch?nemann Jensen Mikkel Marcker Stubgaard Niklas Rausch Norbert Nadudvari Oana Simionescu Richard Howis Sabine Kokina Simonas Petrakas Sofia Sofianou Takumi Iwasawam Tobias Hjortdal Tommy Bj?rnstrup Victor Bejenaru Xiao Xuan Lu Rasmus Hjortshoj 曲鸿

格拉西尔坐落于法罗群岛起伏的峡湾上,坐拥大海和青翠的海湾景观,首都托尔斯港的景色一览无余。格拉西尔旨在把法罗群岛体育学校、托尔斯港技术学院和法罗群岛商学院合并在一起,提高整体效率,惠及1 750名师生和员工。通过创新孵化器的形... 详细信息

格拉西尔坐落于法罗群岛起伏的峡湾上,坐拥大海和青翠的海湾景观,首都托尔斯港的景色一览无余。格拉西尔旨在把法罗群岛体育学校、托尔斯港技术学院和法罗群岛商学院合并在一起,提高整体效率,惠及1 750名师生和员工。通过创新孵化器的形式,不同于传统学校,格拉西尔既保留了三所学校的自主权,又为学校之间合作学习的蓬勃发展创造了理想条件。根据学生和教师的内部需求,

关键词：法罗群岛教师准备托尔斯港格拉西平面图卫生间教育中心

Coping with Infertility: An Explorative Study of South African Women’s Experiences

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Open Journal of Obstetrics and Gynecology 2015年第1期5卷 49-59页

作者： athena Pedro Psychology Department University of the Western Cape Bellville South Africa

The expectation of getting married and having children is for many individuals a natural part of adult life. Many young people anticipate the prospect of becoming biological mothers and fathers. This expectation of parenthood emanates as individuals and couples are socially groomed to aspire to this social norm. Therefore, infertility can be a very traumatic and tormenting time for many men and women who aspire to conform to these socio-cultural conventions of normative parenthood and who believe that childbearing is central to their lives. Infertility is medically defined as the inability to achieve a pregnancy after a period of at least twelve months of regular sexual intercourse without contraception. For both men and women infertility may present pervasive feelings of incompleteness, a sense of failure and inadequacy. However, infertile women tend to endure a myriad of feeling losses and high levels of suffering and sorrow as a result of their inability to have children. This study explored a sample of South Africa women’s experiences of coping with infertility. Utilising a qualitative methodology, a diverse group of 21 married women who were diagnosed with primary infertility were recruited. Semi-structured, in-depth individual interviews were conducted and the data were analysed using thematic analysis. The results of the study indicated that the women reported emotional turmoil characterised by emotions such as disappointment and shock, anger and frustration, a deep sense of sadness and then progressed to experience a sense of acknowledgement that a problem existed. The findings of this study suggest that severe psychological and emotional strain accompany infertility. The coping strategies employed by these women in the study included social withdrawal and women isolating themselves from social events and social gatherings, avoiding pregnant women and women with children, engaging in escapism strategies on both a psychological level and a physical level. Emp

关键词： Infertility Psychological and Emotional Trauma Motherhood Involuntary Childlessness Coping

An Efficient 3D CNN Framework with Attention Mechanisms for Alzheimer’s Disease Classification

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Computer Systems Science & Engineering 2023年第11期47卷 2097-2118页

作者： athena George Bejoy Abraham Neetha George Linu Shine Sivakumar Ramachandran Department of Electronics and Communication Engineering College of EngineeringTrivandrum695016India Department of Computer Science and Engineering College of Engineering MuttatharaTrivandrum695008India Department of Electronics and Communication Rajeev Gandhi Institute of TechnologyKottayam686501India Department of Electronics and Communication Engineering Government Engineering CollegeWayanad670644India

Neurodegeneration is the gradual deterioration and eventual death of brain cells,leading to progressive loss of structure and function of neurons in the brain and nervous *** disorders,such as Alzheimer’s,Huntington’s,Parkinson’s,amyotrophic lateral sclerosis,multiple system atrophy,and multiple sclerosis,are characterized by progressive deterioration of brain function,resulting in symptoms such as memory impairment,movement difficulties,and cognitive *** diagnosis of these conditions is crucial to slowing down cell degeneration and reducing the severity of the *** resonance imaging(MRI)is widely used by neurologists for diagnosing brain *** majority of the research in this field focuses on processing the 2D images extracted from the 3D MRI volumetric scans for disease *** might result in losing the volumetric information obtained from the whole brain *** address this problem,a novel 3D-CNN architecture with an attention mechanism is proposed to classify whole-brain MRI images for Alzheimer’s disease(AD)*** 3D-CNN model uses channel and spatial attention mechanisms to extract relevant features and improve accuracy in identifying brain dysfunctions by focusing on specific regions of the *** pipeline takes pre-processed MRI volumetric scans as input,and the 3D-CNN model leverages both channel and spatial attention mechanisms to extract precise feature representations of the input MRI volume for accurate *** present study utilizes the publicly available Alzheimer’s disease Neuroimaging Initiative(ADNI)dataset,which has three image classes:Mild Cognitive Impairment(MCI),Cognitive Normal(CN),and AD *** proposed approach achieves an overall accuracy of 79%when classifying three classes and an average accuracy of 87%when identifying AD and the other two *** findings reveal that 3D-CNN models with an attention mechanism exhibit significantly higher classi

关键词： 3D CNN alzheimer’s disease attention mechanism classification

An exploratory study of South African women’s experiences of In Vitro Fertilisation and Embryo Transfer (IVE-ET) at fertility clinics

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Open Journal of Preventive Medicine 2013年第8期3卷 470-478页

作者： athena Pedro Kelvin Mwaba Department of Psychology University of the Western Cape Bellville South Africa

Infertility is considered to be a growing problem worldwide. In sub-Saharan Africa, at least 20%-50% of couples of reproductive age experience a fertility problem and 30% are diagnosed with infertility. This study explores the experiences of women in South Africa who are involuntary childless and explores their psychological and emotional experiences of In Vitro Fertilisation and Embryo Transfer (IVF-ET). Utilising a qualitative methodology, a diverse group of 21 married women diagnosed with infertility and who had undergone at least two cycles of IVF-ET were recruited. Semi-structured, in-depth individual interviews were conducted and the data were analysed using thematic analysis. The results of the study indicated that the women perceived themselves as not conforming to a dominant belief system and as a result felt compelled to explore all the medical options available. They reported emotional turmoil characterised by primary binary emotions of anxiety-excitement and nervousness-optimistic. These emotions were experienced throughout the five stages of the IVF-ET treatment cycles. A synopsis of the psychological and emotional responses to the IVF-ET treatment is discussed. The findings of this study suggest the need for the incorporation of a mandatory psychosocial intervention as part of infertility management. Greater attention to the psychological and emotional repercussions of infertility treatment could lead to a more personalised client-approach which, in turn, would prepare infertile women and couples for the emotional demands of the treatment.

关键词： Infertility In Vitro Fertilisation and Embryo Transfer Social Constructionist Psychological and Emotional

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Mouth or Mouse

棒棒英语（中、英文对照） 2011年第12期 22-23页

作者： athena 符劼（图）

最近花音小姐家中鼠患成灾，用什么对付老鼠既环保又有效？当然是养一只能干的猫咪啦!

关键词：英语教学教学方法阅读教学小学

A Qualitative Exploration of South African Women’s Psychological and Emotional Experiences of Infertility

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Open Journal of Preventive Medicine 2014年第5期4卷 327-337页

作者： athena Pedro Michelle Andipatin Psychology Department University of the Western Cape Bellville South Africa

Despite the high prevalence of infertility in Africa, the study of reproductive health in Africa, has for the most part, not addressed the impact of involuntary childlessness on women. In contrast, the health priority has been on fertility regulation rather than on infertility. In Sub-Saharan Africa, at least 20% - 50% of couples of reproductive age experience a fertility problem and 30% are diagnosed with infertility. This study explored a sample of South Africa women’s psychological and emotional experiences of infertility or involuntary childlessness. Utilising a qualitative methodology, 21 married women who were diagnosed with infertility were recruited. Semi-structured, indepth individual interviews were conducted and the data were analysed using thematic analysis. The results of the study indicated that the women reported emotional turmoil characterised by emotions such as disappointment and shock, anger and frustration, a deep sense of sadness and then progressed to experience a sense of acknowledgement that a problem existed. Within each of these emotional phases the emotions of hope and optimism were present. The findings of this study suggest that severe psychological and emotional tug-of-war effects accompany infertility. Possible coping strategies for women struggling with infertility are discussed.

关键词： Infertility Psychological and Emotional Trauma Motherhood Involuntary Childlessness

Potential risk of liver injury in epileptic patients during COVID-19 pandemic

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World Journal of Virology 2022年第6期11卷 467-476页

作者： Nasim Tabrizi athena Sharifi-Razavi Department of Neurology Mazandaran University of Medical SciencesSari ***Iran

Most of the antiseizure medications(ASMs)are metabolized in liver and many of them particularly first-generation ASMs have the potential to increase liver enzymes or induce liver ***,treatment of new onset seizures or epilepsy by ASMs during the course of coronavirus disease 2019(COVID-19),which could potentially be complicated by hepatic dysfunction,is a challenging clinical *** form of levetiracetam which has no significant hepatic metabolism or drug-drug interaction is often a favorable option to control seizures in acute phase of *** of enzyme inducer ASMs and valproate with the well-known hepatotoxicity and common drug interactions is not generally *** patients with epilepsy who are under control with potentially hepatotoxic ASMs,close observation and cautious dose reduction or drug switch should be considered if any evidence of hepatic impairment ***,risks of possible breakthrough seizures should be weighed against benefits of lowering the hazard of liver *** patients with epilepsy who receive polytherapy with ASMs,transient dose modification with the tendency to increase the dose of ASMs with more favorable safety profile and less drug interaction and decrease the dose of drugs with main hepatic metabolism,high protein binding,potential to cause liver injury and known drug-drug reaction should be ***,decision making should be individualized based on patients’conditions and course of illness.

关键词： COVID-19 Epilepsy Seizure Drug induced liver injury Corona virus Hepatic failure

Survey on Public Key Cryptography Scheme for Securing Data in Cloud Computing

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Circuits and Systems 2017年第3期8卷 77-92页

作者： J. athena V. Sumathy Department of ECE Government College of Technology Coimbatore India

Numerous advancements in the Information Technology (IT) require the proper security policy for the data storage and transfer among the cloud. With the increase in size of the data, the time required to handle the huge-size data is more. An assurance of security in cloud computing suffers various issues. The evolution of cryptographic approaches addresses these limitations and provides the solution to the data preserving. There are two issues in security assurance such as geographical distribution and the multi-tenancy of the cloud server. This paper surveys about the various cryptographic techniques with their key sizes, time required for key/signature generation and verification constraints. The survey discusses the architecture for secure data transmissions among the devices, challenges raised during the transmission and attacks. This paper presents the brief review of major cryptographic techniques such as Rivest, Shamir Adleman (RSA), Dffie Hellman and the Elliptic Curve Cryptography (ECC) associated key sizes. This paper investigates the general impact of digital signature generation techniques on cloud security with the advantages and disadvantages. The results and discussion section existing in this paper investigate the time consumption for key/signature generation and verification with the key size variations effectively. The initialization of random prime numbers and the key computation based on the points on the elliptic curve assures the high-security compared to the existing schemes with the minimum time consumption and sizes in cloud-based applications.

关键词： Cloud Computing Cryptography RSA Diffie Hellman Elliptic Curve Cryptography Digital Signature