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A Microcalorimetry and Spectroscopy Study on the Interaction of BSA with 2,2′-Bipyridine Octylglycinato Palladium(II) Nitrate

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Acta Biochimica et Biophysica Sinica 2003年第10期35卷 886-890页

作者： MANSOORI-TORSHIZI Hassan,ISLAMI-MOGHADDAM Mahbobe,SABOURY Ali akbar Institute of Biochemistry and Biophysics Department of Chemistry Institute of Biochemistry and Biophysics University of Tehran Tehran 14176-14411 Iran Department of Chemistry University of Sistan & Bluchestan Zahedan 98167-45345 Iran University of Sistan & Bluchestan Zahedan 98167-45345 Iran University of Tehran Tehran 14176-14411 Iran

The interaction of bovine serum albumin (BSA) with a new palladium(II) complex [Pd(bpy)(Oct-Gly)]NO 3 (bpy, 2,2′-bipyridine; Oct-Gly, octyl-glycine) was studied by isothermal titration UV-visible spectrophotometry and microcalorimetry in 30 mmol/L Tris buffer, pH 7.0. There is a set of 18 binding sites for this complex on BSA at 300 and 310 K with positive cooperativity in the binding process. The Hill coefficients at 300 and 310 K are 2.2 and 2.4, respectively. The binding of this palladium complex on BSA is endothermic with mean association binding constant of 21.0 and 16.4 (mmol/L) -1 at 300 and 310 K, respectively. The complex can denature the protein as surfactants. The stability of BSA in the interaction study with the complex is 84 and 58 kJ/mol at 300 and 310 K, respectively. Also, the enthalpy of BSA denaturation due to the interaction with the complex is 842 kJ/mol.

关键词： serum albumin palladium complex isothermal titration microcalorimetry spectrophotometry

Blood flow analysis in tapered stenosed arteries with pseudoplastic characteristics

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International Journal of Biomathematics 2014年第6期7卷 89-106页

作者： Noreen Sher akbar S. Nadeem National University of Sciences and Technology Islamabad Pakistan Department of MathematicsQuaid-i-Azam University 45320 Islamabad 44000 Pakistan

In this paper, the blood flow through a tapered artery with a stenosis by considering axially non-symmetric but radially symmetric mild stenosis on blood flow characteristics is analyzed, assuming the flow is steady and blood is treated as Williamson fluid. Per- turbation solutions have been evaluated for velocity, resistance impedance, wall shear stress and shearing stress at the stenosis throat. The graphical results of different type of tapered arteries （i.e. converging tapering, diverging tapering, non-tapered artery） have been examined for different parameters of interest.

关键词： Williamson fluid blood flow tapered artery stenosis perturbation solution.

Mathematical analysis of Phan-Thien-Tanner fluid model for blood in arteries

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International Journal of Biomathematics 2015年第5期8卷 215-230页

作者： Noreen Sher akbar S. Nadeem INational University of Sciences and Technology Islamabad Pakistan Department of Mathematics Quaid-i-Azam University45320 Islamabad 44000 Pakistan

In the present paper, we have studied the blood flow through tapered artery with a stenosis. The non-Newtonian nature of blood in small arteries is analyzed mathematically by considering the blood as Phan-Thien-Tanner fluid. The representation for the blood flow is through an axially non-symmetrical but radially symmetric stenosis. Symmetry of the distribution of the wall shearing stress and resistive impedance and their growth with the developing stenosis is another important feature of our analysis. Exact solutions have been evaluated for velocity, resistance impedance, wall shear stress and shearing stress at the stenosis throat. The graphical results of different type of tapered arteries （i.e. converging tapering, diverging tapering, non-tapered artery） have been examined for different narameters of interest.

关键词： Phan-Thien-Tanner fluid blood flow tapered artery stenosis exact solu-tions.

Evaluating land subsidence by field survey and D-In SAR technique in Damaneh City, Iran

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Journal of Arid Land 2017年第5期9卷 778-789页

作者： akbar GHAZIFARD Elham akbarI Koroush SHIRANI Homayon SAFAEI Department of Geology Faculty of Science University of Isfahan Isfahan 81746-73441 Iran Department of Soil Conservation and Watershed Management Isfahan Agricultural and Natural Resources Research and Education Center Isfahan 81748-35118 Iran

Based on the data from piezometers, well logs, geophysical surveys and the interferometric synthetic aperture radar（In SAR） technique, this study investigates the main causes of land subsidence in Damaneh City, Iran. The size, openings and direction of fissures were measured by micrometer and compass. The locations of fissures and wall cracks were determined by GPS. The geoelectrical data were used to determine the composition, thickness, depth and shape of lower parts of the aquifer. Groundwater fluctuations were evaluated by available piezometers. The In SAR technique was used to measure land deformation from space and to map the dense changes of surface displacements. The results indicate that the main cause of ground subsidence is the decline of groundwater heads and changes in composition and thickness of compressible lacustrine sediments. The subsidence map obtained from the radar data of ASAR sensor of ENVISAT satellite shows that the subsidence zone is mainly in northern city that is underlain by very thick fine sediments. The subsidence rates from March to December 2005 and from July 2011 to January 2012 are 6.7 and 7.0 cm/a, respectively. The results also show good correlations among the formation of earth features, decline in groundwater head and thickness of fine-grained sediments. We recommend that the groundwater withdrawal for agricultural and industrial sectors should be restricted and urban expansion in the northern part of the city should be constrained.

关键词： land subsidence water withdrawal D-interferometric synthetic aperture radar Damaneh City

Neutrosophic N-Structures Applied to Sheffer Stroke BL-Algebras

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Computer Modeling in Engineering & Sciences 2021年第10期129卷 355-372页

作者： Tugce Katican Tahsin Oner akbar Rezaei Florentin Smarandache Department of Mathematics Ege UniversityIzmir35100Turkey Department of Mathematics Payame Noor UniversityTehran19395-4697Iran Department of Mathematics and Science University of New MexicoGallup87301NMUSA

In this paper,we introduce a neutrosophic N-subalgebra,a(ultra)neutrosophic N-filter,level sets of these neutrosophic N-structures and their properties on a Sheffer stroke *** defining a quasi-subalgebra of a Sheffer stroke BL-algebra,it is proved that the level set of neutrosophic N-subalgebras on the algebraic structure is its quasi-subalgebra and vice *** we show that the family of all neutrosophic N-subalgebras of a Sheffer stroke BL-algebra forms a complete distributive *** that a(ultra)neutrosophic N-filter of a Sheffer stroke BL-algebra is described,we demonstrate that every neutrosophic N-filter of a Sheffer stroke BL-algebra is its neutrosophic N-subalgebra but the inverse is generally not ***,it is presented that a level set of a(ultra)neutrosophic N-filter of a Sheffer stroke BL-algebra is also its(ultra)filter and the inverse is always ***,some features of neutrosophic N-structures on a Sheffer stroke BL-algebra are investigated.

关键词： Sheffer stroke BL-algebra (ultra)filter neutrosophic N-subalgebra (ultra)neutrosophic N-filter

Bright, periodic, compacton and bell-shape soliton solutions of the extended QZK and (3+1)-dimensional ZK equations

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Communications in Theoretical Physics 2021年第10期73卷 23-35页

作者： M Ali akbar Md Abdul Kayum M S Osman Department of Applied Mathematics University of RajshahiBangladesh Department of Computer Science&Engineering North Bengal International UniversityRajshahiBangladesh Department of Mathematics Faculty of ScienceCairo UniversityGiza 12613Egypt

The(3+1)-dimensional Zakharov–Kuznetsov(ZK) and the new extended quantum ZK equations are functional to decipher the dense quantum plasma, ion-acoustic waves, electron thermal energy,ion plasma, quantum acoustic waves, and quantum Langmuir waves. The enhanced modified simple equation(EMSE) method is a substantial approach to determine competent solutions and in this article, we have constructed standard, illustrative, rich structured and further comprehensive soliton solutions via this method. The solutions are ascertained as the integration of exponential, hyperbolic,trigonometric and rational functions and formulate the bright solitons, periodic, compacton, bellshape, parabolic shape, singular periodic, plane shape and some new type of solitons. It is worth noting that the wave profile varies as the physical and subsidiary parameters change. The standard and advanced soliton solutions may be useful to assist in describing the physical phenomena previously mentioned. To open out the inward structure of the tangible incidents, we have portrayed the three-dimensional, contour plot, and two-dimensional graphs for different parametric values. The attained results demonstrate the EMSE technique for extracting soliton solutions to nonlinear evolution equations is efficient, compatible and reliable in nonlinear science and engineering.

关键词： (3+1)-dimensional ZK the extended QZK equation enhanced modified simple equation method soliton solutions NLEEs

A comprehensive experimental evaluation of asphaltene dispersants for injection under reservoir conditions

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Petroleum Science 2016年第2期13卷 280-291页

作者： Hamed Firoozinia Kazem Fouladi Hossein Abad akbar Varamesh Research Institute of Petroleum Industry Tehran *** Iran

As the efficiency of dispersants with different origins is questionable for each typical oil sample, the present study provides a reproducible and reliable method for screening asphaltene dispersants for a typical asphal- tenic crude oil. Four different asphaltene dispersants （polyisobutylene succinimide, polyisobutylene succinic ester, nonylphenol-formaldehyde resin modified by polyamines, and rapeseed oil amide） were prepared and their performance on two oils from an Iranian field under laboratory and reservoir conditions was studied. A thorough analysis including ash content and SARA tests was performed on the solid asphaltene particles to characterize the nature of deposits. Then a highly efficient carrier fluid, which is crucial when injecting dispersant into the wells, was selected from a variety of chemicals by comparing their solubility. In the next step, using an optical microscope, a viscometer, and a Turbiscan, the screening of dispersants under laboratory conditions was done on a mixture of dead oil and dispersant to evaluate the onset of asphaltene precipitation and its stability when titrating by a precipitant. Finally, two different mixtures of the efficient dispersants, live oil, and carrier fluid were used with the solid detection system （SDS） and the filtration method to examine their effects on the onset pressure of asphaltene precipitation and the asphaltene content of the crude oil under reservoir conditions. The results show that the combination of experimental methods used in this work could be consistently applied to screening asphaltene dispersants. Among the four different dispersants applied here, the dispersant based on nonylphenol-formaldehyde resin modified by polyamines showed the best performance on the available live oils. This chemical modified the onset pressure of asphaltene precipitation of light oil from 4300 psi to about 3600 psi and decreased the precipitated asphaltene of heavy oil by about 30 %.

关键词： Asphaltene Dispersant Solvent Onsetpoint Precipitation Deposition

牙源性间充质干细胞来源的外泌体在牙周免疫调节的研究进展

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口腔疾病防治 2024年第10期32卷 814-820页

作者：艾克帕尔·艾尔肯陈晓涛新疆维吾尔自治区人民医院新疆维吾尔自治区乌鲁木齐830000 新疆维吾尔自治区人民医院口腔科新疆维吾尔自治区乌鲁木齐830000

外泌体(exosomes,EXOs)是细胞间通讯的重要介质,其内含有多种物质,包括miRNA、mRNA、DNA和蛋白质等,可通过多种方式作用于靶细胞。外泌体作为“无细胞治疗”手段,具有广阔的医学应用前景。EXOs的内含物随供体细胞及其状态的变化而变化,... 详细信息

外泌体(exosomes,EXOs)是细胞间通讯的重要介质,其内含有多种物质,包括miRNA、mRNA、DNA和蛋白质等,可通过多种方式作用于靶细胞。外泌体作为“无细胞治疗”手段,具有广阔的医学应用前景。EXOs的内含物随供体细胞及其状态的变化而变化,因此来自不同类型细胞的EXOs可能表现出不同的生物学效应。牙源性间充质干细胞来源的EXOs因其在组织再生医学和免疫调节领域表现出的生物学特性而受到越来越多的关注。在牙周免疫调节过程中促炎型(M1型)/抗炎型(M2型)巨噬细胞以及辅助性T细胞(Th17)/调节性T细胞(Treg)之间的平衡转化是研究热点。现有研究表明,牙源性间充质干细胞来源的EXOs能够促进巨噬细胞和T细胞的转化并且这种功能可能取决于周围微环境以及干细胞的组织来源等因素,如牙髓间充质干细胞来源的EXOs中的miR-1246通过抑制NF-κB P65从而促进M2型巨噬细胞的极化;根尖牙乳头间充质干细胞来源的EXOs通过促进DNA去甲基化酶Tet2(Tet methylcytosine dioxygenase 2,Tet2)介导的FoxP3的去甲基化,维持FoxP3的稳定表达,促进Treg转化,从而缓解牙周炎局部炎症。此外炎症相关因子可以影响牙源性间充质干细胞来源的EXOs的免疫调节活性,如脂多糖预处理的牙囊间充质干细胞来源的EXOs可通过ROS/JNK信号通路降低RANKL/OPG比例,并通过ROS/ERK信号通路促进巨噬细胞向M2型极化;肿瘤坏死因子-α和干扰素-α两种促炎细胞因子预处理的牙龈间充质干细胞来源的EXOs通过高表达CD73和CD5L从而促进M2型巨噬细胞的极化;牙周炎患者牙周膜间充质干细胞来源的EXOs促进巨噬细胞向M1表型极化。本文综述牙源性间充质干细胞来源的EXOs在牙周免疫调节过程中对两种细胞平衡转化影响的研究进展,为EXOs治疗牙周炎提供参考。

关键词：牙周炎牙源性间充质干细胞外泌体 M1型巨噬细胞 M2型巨噬细胞 Th17细胞 Treg细胞免疫调节

Extraordinary adsorption of acidic fuchsine and malachite green onto cheap nano-adsorbent derived from eggshell

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Chinese Journal of Chemical Engineering 2020年第6期28卷 1591-1602页

作者： Atefeh Moosavi Ali akbar Amooey Ali Alinejad mir Mojtaba Hedayati Marzbali Faculty of Chemistry University of MazandaranBabolsarIran Department of Chemical Engineering University of MazandaranBabolsarIran Chemical&Environmental Engineering School of EngineeringRMIT UniversityMelbourneVictoria 3000Australia

Removal of dyestuffs such as Acidic Fuchsine(AF)and Malachite Green(MG)being present in many forms in industries is vital to protect water reservoirs from their catastrophic effects on the *** study attempts to effectively eliminate these dyes using a low-cost and eco-friendly ***,as a biocompatible by-product,was initially characterized,then some modifications were conducted,and its morphology and chemical structure were then examined through(Atomic force microscopy)AFM,(Fourier-Transform Infrared Spectroscopy)FTIR,(Energy-Dispersive X-ray Spectroscopy)EDS and(Brunauer–Emmett–Teller)BET *** revealed that the modifications on raw material gave rise to a natural nano-adsorbent presenting porous medium appropriate for targeted adsorbate molecules with the average particle size and average pore diameter of 54 and^2 nm,*** groups on the adsorbent surface were also of importance to assist the adsorption of AF and *** effect of contact time,adsorbent dose,solution p H and initial concentration was ***-second order model accurately correlated the experimental kinetic data for both ***,the participation of intra-particle diffusion along with film diffusion in controlling the process was *** isotherm model fitted very well to the equilibrium data for both dyes and maximum monolayer adsorption capacity of AF and MG was accordingly calculated to be 5000 and 3333.33 mg·g-1 *** inherent characteristics of eggshell make it a potential material to remove contaminants from wastewater in future applications.

关键词： Egg shell Acidic Fuchsine Malachite Green Ultrahigh adsorption