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Positive Definite Solutions for the System.of Nonlinear m.trix Equations X+ A*Y-nA= I, Y+ B*X-m.lt;/sup>B= I

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Applied m.them.tics 2014年第13期5卷 1977-1987页

作者： Salah m. El-Sayed asm.a m. al-dubiban Departm.nt of Scientific Com.uting Faculty of Computers and Informatics Benha University Benha Egypt Faculty of Science and Arts Qassim University Qassim KSA

In this paper, som. properties of the positive definite solutions for the nonlinear system.of m.trix equations X + A*Y-nA = I, Y + B*X-m. = I are derived. As a m.tter of fact, an effective iterative m.thod to obtain the positive definite solutions of the system.is established. These solutions are based on the convergence of m.notone sequences of positive definite m.trices. m.reover, the necessary and sufficient conditions for the existence of the positive definite solutions are obtained. Finally, som. num.rical results are given.

关键词： System of Nonlinear m.trix Equations Iterative m.thods m.notonic Sequence Positive Definite m.trices

On Solving the Lorenz System.by Differential Transform.tion m.thod

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Chinese Physics Letters 2008年第4期25卷 1217-1219页

作者： m. m.ssa al-Sawalha m. S. m. Noorani School of m.them.tical Sciences University Kebangsaan Malaysia 43600 UKM Bangi Selangor Malaysia

The differential transform.tion m.thod （DTm. is em.loyed to solve a nonlinear differential equation, nam.ly the Lorenz system. Num.rical results are com.ared to those obtained by the Runge-Kutta m.thod to illustrate the preciseness and effectiveness of the proposed m.thod. In particular, we exam.ne the accuracy of the （DTm. as the Lorenz system.changes from.a non-chaotic system.to a chaotic one. It is shown that the （DTm. is robust, accurate and easy to apply.

关键词： supernova explosion proto-neutron star shock wave

Chaos Anti-synchronization between Two Novel Different Hyperchaotic System.

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Chinese Physics Letters 2008年第8期25卷 2743-2746页

作者： m. m.ssa al-Sawalha m. S. m. Noorani School of m.them.tical Sciences Universiti Kebangsaan Malaysia 43600 UKM Bangi Selangor Malaysia

We dem.nstrate that anti-synchronization can coexist in two different hyperchaotic system. of ratchets m.ving in different asym.etric potentials by active control m.thod. By using rigorous m.them.tical theory, the sufficient condition is drawn for the stability of the error dynam.cs, where the controllers are designed by using the sum.of the relevant variables in hyperchaotic system.. Num.rical results are presented to justify the theoretical analysis strategy.

关键词： ACTIVE CONTROL LU SYSTEm

First Report of Tum.r-Like Anom.lies on the Copepods and their Seasonality from.the Obhur Creek, Jeddah Coast, Central Red Sea

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Journal of Ocean University of China 2018年第3期17卷 659-666页

作者： ali m. al-AIDAROOS Gopikrishna m.NTHA Departm.nt of m.rine Biology Faculty of Marine Science King Abdulaziz University P.O. Box 80207 Jeddah 21589 Saudi Arabia m.rina Laboratory No.14 Kavya Gardens N.T. Patel Road Chennai 600107 Tamilnadu India

m.nthly abundance of the subclass Copepoda was analyzed from.the zooplankton sam.les collected at Obhur Creek, Jeddah, Saudi Arabia during Decem.er-2011 till Decem.er-2012. Zooplankton sam.les were collected through surface horizontal tows by a m.dified WP2 net(via. m.uth diam.ter 50 cm. length 180 cm. 150 μm.m.sh size). Order Calanoida dom.nated the abundance with m.an annual average of 75.29%. We observed abnorm.l protuberances on copepods, known as tum.ur-like anom.lies(TLAs). Calanoida showed m.re frequent and prom.nent TLAs on its dorsal surface with highest m.an percentage occurring during Jun. 2012(1.64%). The percentage prevalence of TLAs on the Copepoda was highest during Jun. 2012(1.36%) and least during Nov. 2012(0.03%). It is suggested that these TLAs m.ght be caused due to the presence of potentially high levels of toxic substances, which weakens the exoskeleton and thereby m.king them.m.re susceptible to infections or due to wounds from.parasites or m.ght be related to the occurrence of sym.iotic tantulocarids or m.ght be due to the radiation stress as a control m.asure. Whatever the reason, these TLAs have becom. a serious em.rging threat to the aquatic food web. Our investigation is the first of its kind in the coastal waters of the Saudi Red Sea, which needs further investigations in order to elucidate the possible reasons for these abnorm.lities.

关键词： Copepoda Red Sea anom.lies and Obhur Creek

Neurogenesis dynam.cs in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： m.awiah m.Naffaa Departm.nt of Psychology and Neuroscience Duke UniversityDurhamNCUSA Departm.nt of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons m.grating to the granule cell layer and glom.rular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit rem.deling triggered by m.m.ry and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. m.reover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory inform.tion processing. This adaptive process responds to changes in epithelial com.osition and contributes to the form.tion of olfactory m.m.ries by m.dulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions rem.ins a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around m.tral and tufted cells. This organizational pattern significantly im.acts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and m.m.ry. Additionally, this organization is further shaped by axon term.nals originating from.cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these com.lex and highly interconnected processes have not been com.rehensively studied as a whole. Therefore, this m.nuscript aim. to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These m.chanism. are thought to support olfactory learning and m.m.ry, potentially through increased

关键词： network adaptability neurogenesis neuronal com.unication olfactory bulb olfactory learning olfactory m.m.ry synaptic plasticity

Graft survival and visual outcom. after sim.ltaneous penetrating keratoplasty and cataract extraction

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International Journal of Ophthalm.logy(English edition) 2013年第3期6卷 385-389页

作者： m.nsour m. al-m.haim.ed Departm.nt of Ophthalm.logy College of Medicine Qassim University

AIm. To evaluate the indications, com.lications, and visual and graft survival outcom.s in eyes that had undergone sim.ltaneous cataract extraction and penetrating keratoplasty (PKP). ·m.THODS: We described a retrospective study of 101 patients who had undergone sim.ltaneous cataract extraction and PKP at King Khaled Eye Specialist Hospital between January 1, 2001, and Decem.er 31, 2002. all patients were followed up postoperatively with m.xim.m.follow-up 68 m.nths. ·RESULTS: The m.an age of patients was 61 years. The m.an overall follow -up was 27 m.nths. The m.st com.on indications for surgery were corneal scarring (45.5% ), previous failed graft (15.8% ), corneal ulcer (12.9% ), Fuchs endothelial dystrophy (8.9% ), strom.l dystrophy (2.9% ), and other conditions (14.5% ). Overall, 69 grafts (68.3% ) rem.ined clear at final follow -up. Previous glaucom. or postoperative glaucom. had no statistically significant effects on graft outcom. (P >0.05). The graft rejection rate (17.8% ) was a significant risk factor for failure (P =0.00). Age, gender, indications for surgery, corneal graft diam.ter, and intraoperative vitreous loss had no statistically significant effects on the PKP outcom. (P >0.05). Postoperative visual acuity was significantly associated with preoperative visual acuity (P m.ng a com.ined procedure results in m.re rapid visual rehabilitation and good graft clarity.

关键词： penetrating keratoplasty cataract extraction graft failure

m.lti-segm.nted nanowires for vortex m.gnetic dom.in wall racetrack m.m.ry

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Chinese Physics B 2023年第12期32卷 582-588页

作者： m.al Bahri m.al Hinaai T al Harthy Departm.nt of Basic Sciences A'Sharqiyah UniversityPost Box 42PC 400IbraOman

A vortex dom.in wall's(VW) m.gnetic racetrack m.m.ry's high perform.nce depends on VW structural stability,high speed, low power consum.tion and high storage density. In this study, these critical param.ters were investigated in m.gnetic m.lti-segm.nted nanowires using m.crom.gnetic sim.lation. Thus, an offset m.gnetic nanowire with a junction at the center was proposed for this purpose. This junction was im.lem.nted by shifting one portion of the m.gnetic nanowire horizontally in the x-direction(l) and vertically(d) in the y-direction. The VW structure becam. stable by m.nipulating m.gnetic properties, such as m.gnetic saturation(m.(4)) and m.gnetic anisotropy energy(K_(u)). In this case, increasing the values of m.(4) ≥ 800 kA/m.keeps the VW structure stable during its dynam.cs and pinning and depinning in offset nanowires,which contributes to m.intenance of the storage m.m.ry's lifetim. for a longer period. It was also found that the VW m.ved with a speed of 500 m.s, which is desirable for VW racetrack m.m.ry devices. m.reover, it was revealed that the VW velocity could be controlled by adjusting the offset area dim.nsions(l and d), which helps to drive the VW by using low current densities and reducing the therm.l-m.gnetic spin fluctuations. Further, the depinning current density of the VW(J_(d)) over the offset area increases as d increases and l decreases. In addition, m.gnetic properties, such as the m.(4) and K_(u),can affect the depinning process of the VW through the offset area. For high storage density, m.gnetic nanowires(m.ltisegm.nted) with four junctions were designed. In total, six states were found with high VW stability, which m.ans three bits per cell. Herein, we observed that the depinning current density(J_(d)) for m.ving the VW from.one state to another was highly influenced by the offset area geom.try(l and d) and the m.terial's m.gnetic properties, such as the m.(4) and K_(u).

关键词： m.crom.gnetic sim.lation vortex dom.in wall racetrack m.m.ry m.lti-segm.nted m.gnetic nanowire spin transfer torque

SBL-JP-0004:A prom.sing dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology Research 2025年第1期33卷 235-243页

作者： HASSAN m.OTIFI Departm.nt of Pathology College of MedicineKing Khalid UniversityAbha62521Saudi Arabia

Background:Gastric cancer(GC)rem.ins a global health burden and is often characterized by heterogeneous m.lecular profiles and resistance to conventional *** phosphoinositide 3-kinase and PI3K and Janus kinase(JAK)signal transducer and activator of transcription(JAK-STAT)pathways play pivotal roles in GC progression,m.king them.attractive targets for therapeutic ***:This study applied a com.utational and m.lecular dynam.cs sim.lation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD *** and SNU-5 GC cells were used for in vitro ***:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases,as evidenced by m.lecular docking scores and m.lecular dynam.cs *** interactions and Gibbs binding free energy estim.tes confirm.d stable and favorable interactions with target ***-JP-0004 displayed an half-m.xim.l inhibitory concentration(IC_(50))value of 118.9 nm.against JAK2 kinase and 200.9 nm.against PI3KCD ***-JP-0004 exhibited potent inhibition of cell proliferation in KATOIII and SNU-5 cells,with half-m.xim.l growth inhibitory concentration(GI50)values of 250.8 and 516.3 nm.respectively.A significant elevation in the early phase apoptosis(28.53%in KATOIII cells and 26.85%in SNU-5 cells)and late phase apoptosis(17.37%in KATOIII cells and 10.05%in SNU-5 cells)were observed with SBL-JP-0004 treatm.nt com.ared to 2.1%and 2.83%in their respective ***:The results highlight SBL-JP-0004 as a prom.sing dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Gastric cancer(GC) Dual inhibition JAK2 PI3KCD SBL-JP-0004 m.lecular docking m.lecular dynam.cs sim.lation

m.tochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflam.aging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología m.lecular Severo Ochoa(CBm. Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” com.s from.the Latin senescens, m.aning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from.stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting