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Role of magnifying narrow-band imaging endoscopy for diagnosis of Helicobacter pylori infection and gastric precancerous conditions:Few issues

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World Journal of Gastroenterology 2022年第15期28卷 1601-1603页

作者： Saroj Kanta sahu Ayaskanta Singh Department of Gastroenterology Sum Ultimate MedicareBhubaneswarOdishaIndia 751003OdishaIndia Department of Gastroenterology IMS and SUM HospitalSOA UniversityBhubaneswar 751003OdishaIndia

Standard endoscopy with biopsy and narrow-band imaging with guided biopsy are techniques for the detection of Helicobacter pylori(***)-related gastritis and precancerous *** this study,the authors compared standard endoscopy and magnified narrow-band imaging(commonly known as NBI-M)in the diagnosis of *** infections,atrophic gastritis,and intestinal *** the sensitivity of NBI-M is better than standard endoscopy,the diagnostic accuracy did not differ substantially between the diagnostic *** prospective studies may guide endoscopists in difficult cases regarding which modality is more useful and cost-effective for the diagnosis of *** gastritis and precancerous conditions.

关键词： Standard endoscopy Magnified narrow band imaging Helicobacter pylori Atrophic gastritis Intestinal metaplasia Pepsinogen

A genetic solution for the global food security crisis

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Journal of Integrative Plant Biology 2023年第6期65卷 1359-1361页

作者： Sunil K.sahu Huan Liu State Key Laboratory of Agricultural Genomics BGI‐ShenzhenShenzhen518083China College of Life Sciences University of Chinese Academy of SciencesBeijing100049China

Due to the rapid increase in population and the decreasing availability of arable land and freshwater resources per capita,global crop production will need to double by 2050 to meet human food *** early March,the World Bank and the Food and Agriculture Organization(FAO)of the United Nations released a report saying that 45 countries are in urgent need of food aid and millions of people are in severe hunger(https://***/en/topic/agriculture/brief/food-security-update).

关键词： global security urgent

Accurate prediction of air quality response to emissions for effective control policy design

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Journal of Environmental Sciences 2023年第1期123卷 116-126页

作者： Min Cao Jia Xing Shovan Kumar sahu Lei Duan Junhua Li State Key Joint Laboratory of Environmental Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China State Environmental Protection Key Laboratory of Sources and Control of Air Pollution Complex Beijing 100084China

Designing effective control policy requires accurate quantification of the relationship between the ambient concentrations of O3and PM2.5and the emissions of their ***,the challenge is that precursor reduction does not necessarily lead to decreases in the concentrations of O3and PM2.5,which are formed by multiple precursors under complex physical and chemical processes;this calls for the development of advanced model technologies to provide accurate predictions of the nonlinear responses of air quality to *** from the traditional sensitivity analysis and source apportionment methods,the reduced form models(RFMs)based on chemical transport models(CTMs)are able to quantify air quality responses to emissions more accurately and efficiently with lower computational *** we review recent approaches used in RFMs and compare their structures,advantages and disadvantages,performance and *** general,RFMs are classified into three types including(1)sensitivity-based models,(2)models with simplified chemistry and physical processes,and(3)statistical models,with considerable differences in principles,characteristics and application *** prediction of nonlinear responses by RFMs enables more in-depth analysis,not only in terms of real-time prediction of concentrations and quantification of human exposure,health impacts and economic damage,but also in optimizing control ***,data assimilation and emission inventory inversion based on the nonlinear response of concentrations to emissions can also be greatly beneficial to air pollution control *** future studies,improvement in the performance of CTMs is exceedingly crucial to obtain a more reliable baseline for the prediction of air quality *** of models to determine the air quality response to emissions under varying meteorological conditions is also necessary in the context of future climate changes,which pose great challenges to the qua

关键词： Air pollution Nonlinear response Air quality management Reduced form models(RFMs) Precursor emissions

A review on recent advancements in biodegradable Mg-Ca alloys

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Journal of Magnesium and Alloys 2022年第8期10卷 2094-2117页

作者： Manas Ranjan sahu T.S.Sampath Kumar Uday Chakkingal Department of Metallurgical and Materials Engineering Indian Institute of Technology MadrasChennai 600036India

The binary Mg-Ca alloys are drawing increasing attention as temporary implant materials because of their excellent biocompatibility,biodegradability, and good mechanical properties. However, their applications are limited due to their high degradation rates in the human physiological environment, the consequent release of hydrogen gas, and rapid loss in mechanical properties. Furthermore, biocompatibility depends upon the degradability of the material. Various researchers have demonstrated that these issues can be addressed by control of Ca content, thermo-mechanical processing to obtain suitable microstructures, deposition of surface coatings, etc. In this manuscript, a detailed review of published literature on Mg-Ca alloys is presented. The challenges and future directions of research in this area are also described.

关键词： Mg-Ca alloy Degradation Temporary implant Biocompatibility

ITERATIVE ALGORITHMS FOR SYSTEM OF VARIATIONAL INCLUSIONS IN HADAMARD MANIFOLDS

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Acta Mathematica Scientia 2022年第4期42卷 1333-1356页

作者： Qamrul Hasan ANSARI Feeroz BABU D.R.sahu Department of Mathematics Aligarh Muslim UniversityAligarh202002India Department of Applied Mathematics Aligarh Muslim UniversityAligarh202002India Department of Mathematics Banaras Hindu UniversityVaranasi 221005India

In this paper,we consider system of variational inclusions and its several spacial cases,namely,alternating point problems,system of variational inequalities,etc.,in the setting of Hadamard *** propose an iterative algorithm for solving system of variational inclusions and study its convergence *** special cases of the proposed algorithm and convergence result are also *** present application to constraints minimization problems for bifunctions in the setting of Hadamard *** the end,we illustrate proposed algorithms and convergence analysis by a numerical *** algorithms and convergence results of this paper either improve or extend known algorithms and convergence results from linear structure to Hadamard manifolds.

关键词： System of variational inclusions altering point problems monotone vector fields strictly pseudocontractive mappings Hadamard manifolds

Ayurveda and in silico Approach: A Challenging Proficient Confluence for Better Development of Effective Traditional Medicine Spotlighting Network Pharmacology

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Chinese Journal of Integrative Medicine 2023年第5期29卷 470-480页

作者： Rashmi sahu Prashant Kumar Gupta Amit Mishra Awanish Kumar Department of Balroga Shri NPA Govt.Ayurveda CollegeRaipur(492010)ChhattisgarhIndia Ayurinformatics Lab Department of KaumarabhrityaAll India Institute of AyurvedaSarita ViharNew Delhi(110076)India Cellular and Molecular Neurobiology Unit Indian Institute of TechnologyJodhpur(342037)RajasthanIndia Department of Biotechnology National Institute of TechnologyRaipur(492010)ChhattisgarhIndia

Coalescence of traditional medicine Ayurveda and in silico technology is a rigor for supplementary development of future-ready effective traditional medicine. Ayurveda is a popular traditional medicine in South Asia, emanating worldwide for the treatment of metabolic disorders and chronic illness. Techniques of in silico biology are not much explored for the investigation of a variety of bioactive phytochemicals of Ayurvedic herbs. Drug repurposing, reverse pharmacology, and polypharmacology in Ayurveda are areas in silico explorations that are needed to understand the rich repertoire of herbs, minerals, herbo-minerals, and assorted Ayurvedic formulations. This review emphasizes exploring the concept of Ayurveda with in silico approaches and the need for Ayurinformatics studies. It also provides an overview of in silico studies done on phytoconstituents of some important Ayurvedic plants, the utility of in silico studies in Ayurvedic phytoconstituents/formulations, limitations/challenges, and prospects of in silico studies in Ayurveda. This article discusses the convergence of in silico work, especially in the least explored field of Ayurveda. The focused coalesce of these two domains could present a predictive combinatorial platform to enhance translational research magnitude. In nutshell, it could provide new insight into an Ayurvedic drug discovery involving an in silico approach that could not only alleviate the process of traditional medicine research but also enhance its effectiveness in addressing health care.

关键词： Ayurveda in silico approach conﬂuence challenge effective therapeutics

Efficacy and safety of pharmacotherapeutic interventions used in visceral leishmaniasis clinical trials:A systematic review and network meta-analysis

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Asian Pacific Journal of Tropical Medicine 2022年第8期15卷 343-353,I0001-I0010页

作者： Aamir Bashir Gautam sahu Ishfaq Rashid Pramil Tiwari Department of Pharmacy Practice National Institute of Pharmaceutical Education and ResearchS.A.S.Nagar Mohali160062PunjabIndia

Objective:To compare the efficacy and safety outcomes of different antileishmanial agents used in visceral leishmaniasis clinical ***:A systematic literature search in PubMed/MEDLINE,EMBASE,Cochrane,and Google Scholar was done using keywords“randomized controlled trials”,“antileishmanial”and“visceral leishmaniasis”.The outcomes included were cure rate,overall withdrawals,relapse rate,and treatment-emergent adverse *** estimates through the frequentist network meta-analysis approach were presented as OR with 95%*** plots were used for identifying the“best intervention”based on p-scores obtained using the surface under the cumulative *** risk of bias was evaluated by using Pedro ***:Seventeen randomized controlled trials with 5143 visceral leishmaniasis patients who received different antileishmanial agents(amphotericin B,miltefosine,paromomycin,meglumine antimoniate,sodium stibogluconate,sitamaquine,and pentavalent antimonials)and met the inclusion criteria were *** efficacy outcomes of the treatments,the rankogram of the network meta-analysis revealed that paromomycin(p-score=0.8148)has the highest probability of being best in the pool,followed by sodium stibogluconate(OR 0.82,95%CI 0.24-2.79,p-score=0.7580),amphotericin B+miltefosine(OR 0.66,95%CI 0.02-19.04,p-score=0.7329)as compared to the remaining treatments;however,the most of the treatment-emergent adverse events were reported with ***:Paromomycin reported the highest cure rates,while the maximum treatment-emergent adverse events were seen with sitamaquine.

关键词： Visceral leishmaniasis Treatment Efficacy Safety Network meta-analysis

Plasma cascaded solid wastes for possible adsorption of NO_(2)in diesel exhaust

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Waste Disposal and Sustainable Energy 2023年第3期5卷 383-393页

作者： Apoorva sahu Shivani Mishra Preeti Jain Bangalore S.Rajanikanth Department of Electrical Engineering Indian Institute of ScienceBangaloreIndia Department of Electrical Engineering Jabalpur Engineering CollegeJabalpurIndia

Extensive use of fossil fuel has led to an increase in solid and gaseous particulates in the environment,which in turn necessitated newer,effective,and economical control strategies to abate pollutants,particularly gaseous *** the current research work,focus has been placed on utilizing industry wastes to adsorb nitrogen oxides present in diesel engine exhaust,which is pre-treated by *** exhaust from a 5 kW diesel generator is exposed to discharge plasma where the oxidation of nitric oxide to nitrogen dioxide occurs,which is then made to flow through another reactor filled with industry wastes drawn from agriculture,foundry,utility,marine industry,etc.,comprising mulberry waste,rice husk,wheat husk,areca nut husk,sugarcane bagasse,coffee husk,foundry sand,lignite ash,red mud,and oyster *** the adsorption of nitrogen dioxide was observed in all the wastes,reduction of nitric oxide was observed in metallic compound-based industry *** about 184 J/L,specific energy plasma cascaded industrial waste red mud yielded 98%NO_(x)removal efficiency,and that with agriculture rice husk waste yielded 53%NOx ***_(2)/Fe_(2)O_(3)present in industry wastes might have exhibited photo-catalysis in visible light resulting in the possible reduction of NO.A new pathway for recycling the waste can be expected through nitrogen dioxide adsorption,and the results are further discussed with respect to plasma-alone and cascaded plasma adsorbent systems.

关键词： Industry waste Electrical discharge Diesel exhaust Nitrogen oxide reduction Agriculture waste Plasma adsorption

Review on the phosphate-based conversion coatings of magnesium and its alloys

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International Journal of Minerals,Metallurgy and Materials 2022年第7期29卷 1435-1452页

作者： Debasis Saran Atul Kumar Sivaiah Bathula David Klaumünzer Kisor K sahu School of Minerals Metallurgical and Materials EngineeringIndian Institute of Technology BhubaneswarBhubaneswar 752050India Group Innovation(COI Battery-Metals) Volkswagen AGWolfsburg 38440Germany Virtual and Augmented Reality Centre of Excellence(VARCOE) Indian Institute of Technology BhubaneswarBhubaneswar 752050India

Magnesium(Mg)and its alloys are lightweight as well as biocompatible and possess a high strength-to-weight ratio,making them suitable for many industries,including aerospace,automobile,and *** major challenge is their high susceptibility to corrosion,thereby limiting their *** considerably lower reduction potential of Mg compared to other metals makes it vulnerable to galvanic *** oxide layer on Mg offers little corrosion resistance because of its high porosity,inhomogeneity,and *** conversion coatings(CCs)belong to a distinct class because of underlying chemical reactions,which are fundamentally different from other types of ***,a CC acts as an intermediate sandwich layer between the base metal and an aesthetic *** chromate CCs offer superior performance compared to phosphate CCs,yet still they release carcinogenic hexavalent chromium ions(Cr^(6+));therefore,their use is prohibited in most European nations under the Registration,Evaluation,Authorization and Restriction of Chemicals legislation ***-based CCs are a cost-effective and environment-friendly ***,this review primarily focuses on different types of phosphate-based CCs,such as zinc,calcium,Mg,vanadium,manganese,and *** discusses their mechanisms,current status,pretreatment practices,and the influence of various parameters-such as pH,temperature,immersion time,and bath composition-on the coating *** challenges associated with phosphate CCs and future research directions are also elaborated.

关键词： phosphate conversion coatings magnesium alloys corrosion zinc phosphate conversion coatings calcium phosphate conversion coatings magnesium phosphate conversion coatings