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The Diagnostic and Prognostic Value of Serum Procalcitonin among Ventilator Associated Pneumonia Patients

Open Journal of Respiratory Diseases 2013年第2期3卷 73-78页

作者： ashraf abd el halim Adel Attia Taysser Zytoun Hosam eldeen Salah Chest Department Faculty of Medicine Zagazig University Zagazig Egypt Clinical Pathology Department Faculty of Medicine Zagazig University Zagazig Egypt Critical Care Department Faculty of Medicine Alexandria University Alexandria Egypt

Ventilator-associated pneumonia (VAP) is a complication in as many as 28% of patients who receive mechanical ventilation. Studies have consistently shown that a delay in diagnosis and treatment increases the mortality risk. The aim of this work was to clarify the role of the serum procalcitonin (PCT) in the diagnosis and the prognosis of ventilator associated pneumonia. Methods: Forty two VAP patients, 20 non VAP-ICU (on mechanical ventilation) admitted patients and 20 healthy control subjects of similar age and sex were included in the study. PCT levels in serum samples were measured in all subjects. Results: There was a highly statistically significant difference (p value 0.001) between VAP patients on one side and non VAP-ICU patients and healthy control subjects on the other side regarding the mean values of PCT. Also, the mean values of PCT were statistically significantly higher (p 0.001) among died VAP group than the survivor VAP group. There was a statistically positive correlation (p = 0.449), CRIP (R = 0.403) and SOFA (R = 0.437)) and initial PCT serum levels. Conclusions: This study found that the increased PCT serum level is an important diagnostic tool for VAP and the PCT serum levels can predict the outcome of VAP patients. We recommend other larger studies to augment our findings.

关键词： Ventilator-Associated Pneumonia (VAP) Procalcitonin (PCT) Acute Physiology and Chronic Health Evaluation II (APACHE II) The Sequential Organ Failure Assessment Score (SOFA) Clinical Pulmonary Infection Score (CPIS)

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Role of Ischemia Modified Albumin in Diagnosis of Pulmonary Embolism

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Open Journal of Respiratory Diseases 2014年第1期4卷 22-26页

作者： ashraf abd el halim Adel Attia Saad Samra Tayseer Zytoun Hosam eldeen Salah Manal Al-Anazi Chest Department Faculty of Medicine Zagazig University Zagazig Egypt Clinical Pathology Department Faculty of Medicine Zagazig University Zagazig Egypt Critical Care Department Faculty of Medicine Alexandria University Alexandria Egypt Resident Internal Medicine King Fahad Specialist Hospital Dammam KSA

Pulmonary embolism is a common and potentially lethal condition. Clinical signs and symptoms for pulmonary embolism are nonspecific. New and simple tests are therefore needed in order to help in early diagnosis of pulmonary embolism. The aim of this work is to elucidate the role of IMA in the diagnosis of pulmonary embolism. Subjects and Methods: 75 patients with suspected pulmonary embolism and 20 control healthy subjects were included in this study. Measurement of IMA was done in all subjects. Results: The mean values of IMA were statistically significantly higher among the PE patient group (0.43 ± 0.104 ABSU) in comparison with non PE patient group (0.27 ± 0.053 ABSU) and healthy control subjects (0.21 ± 0.080 ABSU). At cut-off value of 0.305 ABSU, IMA had 97.5% sensitivity and 71.42% specificity. The area under the curve was 0.952. The positive predictive value of this cut-off value was 79.59% while the negative predictive value was 96.15%. Conclusions: IMA is a good alternative to D-dimer in the diagnosis and exclusion of PE. Larger studies are needed to augment our results.

关键词： Ischemia Modified Albumin D-Dimer Pulmonary Embolism

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Solid Waste Management:A MADM Approach Using Fuzzy Parameterized Possibility Single-Valued Neutrosophic Hypersoft Expert Settings

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 531-553页

作者： Tmader Alballa Muhammad Ihsan Atiqe Ur Rahman Noorah Ayed Alsorayea Hamiden abd el-Wahed Khalifa Department of Mathematics College of SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia 2 Department of Mathematics University of Management and TechnologyLahore54000Pakistan Department of Mathematics College of ScienceQassim UniversityBuraydah51452Saudi Arabia

The dramatic rise in the number of people living in cities has made many environmental and social problems *** search for a productive method for disposing of solid waste is the most notable of these *** scholars have referred to it as a fuzzy multi-attribute or multi-criteria decision-making problem using various fuzzy set-like approaches because of the inclusion of criteria and anticipated *** goal of the current study is to use an innovative methodology to address the expected uncertainties in the problem of solid waste site *** characteristics(or sub-attributes)that decision-makers select and the degree of approximation they accept for various options can both be indicators of these *** tackle these problems,a novel mathematical structure known as the fuzzy parameterized possibility single valued neutrosophic hypersoft expert set(ρˆ-set),which is initially described,is integrated with a modified version of Sanchez’s *** this,an intelligent algorithm is *** steps of the suggested algorithm are explained with an example that explains *** compatibility of solid waste management sites and systems is discussed,and rankings are established along with detailed justifications for their *** study’s strengths lie in its application of fuzzy parameterization and possibility grading to effectively handle the uncertainties embodied in the parameters’nature and alternative approximations,*** uses specific mathematical formulations to compute the fuzzy parameterized degrees and possibility grades that are missing from the prior *** is simpler for the decisionmakers to look at each option separately because the decision is *** the computed results,it is discovered that they are consistent and dependable because of their preferred properties.

关键词： Hypersoft expert set Sanchez’s method decision making optimization solid waste management possibility grade fuzzy parameterization

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Lanthanide amino acid Schiff base complexes:synthesis,spectroscopic characterization,physical properties and in vitro antimicrobial studies

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Journal of Rare Earths 2013年第7期31卷 715-721页

作者： Samir Alghool M.Sh.Zoromba Hanan F.abd el-halim Department of Chemistry Faculty of SciencePort Said UniversityPort Said 42521Egypt Department of Chemistry Faculty of PharmacyMisr International UniversityIsmailia RoadKm 28 CairoEgypt

Complexes of La （III）, Nd（III）, Gd（III）, Sm（III）, and Ce（IV） were synthesized with Schiff base [（3,5-di-tert-butyl-2-hy- droxybenzyl） amino] acetic acid （H3L）. The ligand and its complexes were synthesized and characterized based on the following analysis： elemental analyses, FAB-mass, molar conductance measurements, magnetic measurement, UV-visible, IR, and NMR spectral studies. The spectral data revealed that the ligand acted as a neutral tridentate coordinating to metal ion through ONO donor sequence. Thermal degradation studies of the ligand and its complexes showed that the previous lanthanide complexes were more thermally stable than the ligand itself. The Schiff base and its complexes were screened for their antibacterial （Escherichia coli, Staphylococcus aureus） and antifungal （Aspergillus flavus and Candida Albicans）.

关键词： lanthanide Schiffbase complexes physical properties biological activity rare earths

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A model of a human heart via graph nano topological spaces

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International Journal of Biomathematics 2019年第1期12卷 115-132页

作者： ashraf S.Nawar abd el Fattah A.el Atik Department of Mathematics Faculty of Science Menoufia UniversityMenoufiaEgypt Department of Mathematics Faculty of Science Tanta UniversityTantaEgypt

In this paper,new forms of nano topological spaces through a neighborhood system of vertices for a digraph will be presented and *** apply the connection between digraph theory and nano topological spaces in the human heart as an example in real *** have a blood flow system in the human heart with respect to oxygenated and deoxygenated blood *** study will be definitely helpful to develop a tool in solving the blood flow system in the human ***,we have succeeded in improving Proposition 1.6 in [7] and Proposition 4.4.1 in [11].

关键词： Digraph isomorphism nano topological spaces neighborhoods

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Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression

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World Journal of Gastroenterology 2016年第10期22卷 2931-2948页

作者： Enas A abd el-Haleim ashraf K Bahgat Samira Saleh Department of Pharmacology and Toxicology Faculty of PharmacyCairo University Currently Faculty of Pharmaceutical Sciences and Pharmaceutical Industries Future University in Egypt

AIM: To evaluate the effect of resveratrol, alone and in combination with fenofibrate, on fructose-induced metabolic genes abnormalities in ***: Giving a fructose-enriched diet (FED) to rats for 12 wk was used as a model for inducing hepatic dyslipidemia and insulin resistance. Adult male albino rats (150-200 g) were divided into a control group and a FED group which was subdivided into 4 groups, a control FED, fenofibrate (FENO) (100 mg/kg), resveratrol (RES) (70 mg/kg) and combined treatment (FENO + RES) (half the doses). All treatments were given orally from the 9th week till the end of experimental period. Body weight, oral glucose tolerance test (OGTT), liver index, glucose, insulin, insulin resistance (HOMA), serum and liver triglycerides (TGs), oxidative stress (liver MDA, GSH and SOD), serum AST, ALT, AST/ALT ratio and tumor necrosis factor-α (TNF-α) were measured. Additionally, hepatic gene expression of suppressor of cytokine signaling-3 (SOCS-3), sterol regulatory element binding protein-1c (SREBP-1c), fatty acid synthase (FAS), malonyl CoA decarboxylase (MCD), transforming growth factor-β1 (TGF-β1) and adipose tissue genes expression of leptin and adiponectin were investigated. Liver sections were taken for histopathological examination and steatosis area were ***: Rats fed FED showed damaged liver, impairment of glucose tolerance, insulin resistance, oxidative stress and dyslipidemia. As for gene expression, there was a change in favor of dyslipidemia and nonalcoholic steatohepatitis (NASH) development. All treatment regimens showed some benefit in reversing the described deviations. Fructose caused deterioration in hepatic gene expression of SOCS-3, SREBP-1c, FAS, MDA and TGF-β1 and in adipose tissue gene expression of leptin and adiponectin. Fructose showed also an increase in body weight, insulin resistance (OGTT, HOMA), serum and liver TGs, hepatic MDA, serum AST, AST/ALT rat

关键词： Fructose Nonalcoholic steatohepatitis Suppressor of cytokine signaling-3 Sterol regulatory element binding protein-1c Fatty acid synthase Malonyl CoA decarboxylase Leptin Adiponectin Transforming growth factor-β Tumor necrosis factor-α

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Effect of different metal sulfate precursors on structural and catalytic performance of zirconia in dehydration of methanol to dimethyl ether

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燃料化学学报 2018年第1期46卷 67-74页

作者： abd el-Aziz A.Said Mohamed abd el-Aal Chemistry Department Faculty of ScienceAssiut University71516 AssiutEgypt

ZrO_2 was treated with 10% SO_4^(2-) from different metal sulfate precursors for methanol dehydration to dimethyl *** the samples exhibited tetragonal phase and no diffraction peaks corresponding to metal sulfates or metal oxides were *** FT-IR results revealed that there were different interactions between sulfate and ZrO_2,and this had a great effect on the surface area of the *** catalytic activity was measured over the catalysts in the temperature range of 100-300 ℃.The results revealed that sulfated zirconia with CuSO_4·5 H_2O and Al_2(SO_4)_3·16 H_2O showed the best catalytic *** maximum yield of DME ≈87% was obtained over CuSZ at a reaction temperature of 275 ℃.Moreover,the catalytic activity of the catalysts was correlated well with their surface acidity that measured by dehydration of isopropanol.

关键词： MSO 4/ZrO2 甲醇脱水 DME

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A Hybrid Security Framework for Medical Image Communication

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Computers, Materials & Continua 2022年第11期73卷 2713-2730页

作者： Walid el-Shafai Hayam A.abd el-Hameed ashraf A.M.Khalaf Naglaa F.Soliman Amel A.Alhussan Fathi E.abd el-Samie Department of electronics and electrical Communications Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Security Engineering Laboratory Department of Computer SciencePrince Sultan UniversityRiyadh11586Saudi Arabia electrical Communications Engineering Department Faculty of EngineeringMinia UniversityMinia61111Egypt Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadhSaudi Arabia

Authentication of the digital image has much attention for the digital *** image authentication can be verified with image watermarking and image encryption *** schemes are widely used to protect images against forgery attacks,and they are useful for protecting copyright and rightful *** on the desirable applications,several image encryption and watermarking schemes have been proposed to moderate this *** framework presents a new scheme that combines a Walsh Hadamard Transform(WHT)-based image watermarking scheme with an image encryption scheme based on Double Random Phase Encoding(DRPE).First,on the sender side,the secret medical image is encrypted using *** the encrypted image is watermarking based on *** combination between watermarking and encryption increases the security and robustness of transmitting an *** performance evaluation of the proposed scheme is obtained by testing Structural Similarity Index(SSIM),Peak Signal-to-Noise Ratio(PSNR),Normalized cross-correlation(NC),and Feature Similarity Index(FSIM).

关键词： Walsh hadamard transform watermarking encryption double random phase encoding structural similarity index

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Corrosion inhibition of carbon steel in hydrochloric acid by cationic arylthiophenes as new eco-friendly inhibitors: Experimental and quantum chemical study

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Chinese Journal of Chemical Engineering 2021年第12期34卷 197-217页

作者： abd el-Aziz S.Fouda Mohamed A.Ismail abdulraqeb A.Al-Khamri ashraf S.Abousalem Department of Chemistry Faculty of ScienceEl-Mansoura UniversityEl-Mansoura 35516Egypt Department of Chemistry Faculty of EducationArts and SciencesUniversity of Saba RegionMaribYemen Quality Control Laboratory Operations DepartmentJotunEgypt

This study describes the adsorption behavior of three arylthiophene derivatives namely:2-(4-amidino-3-fluorophenyl)-5-[4-methoxy phenyl] thiophene dihydrochloride salt(MA-1217),2-(4-amidinophenyl)-5-[4-chlorophenyll thiophene dihydrochloride salt(MA-1316) and 2-(4-amidino-3-fluorophenyl)-5-[4-ch lorophenyllthiophene dihydrochloride salt(MA-1312) at C-steel in 1.0 mol·L^(-1) HCl interface using experimental and theoretical *** and mass loss measurements showed that the inhibition efficiency(IE) of the arylthiophene derivatives increases with increasing concentrations and exhibited maximum efficiency 89% at 21×10^(-6) mol·L^(-1)(MA-1217) by mass loss *** investigated arylthiophene derivatives obey the Langmuir adsorption *** polarization studies the arylthiophene derivatives act as mixed-type *** analysis were carried out and *** mode of orientation and adsorption of inhibitor molecules on C-steel surface was studied using molecular dynamics(MD) *** chemical parameters as well as the radial distribution function indices and binding energies confirm the experimental results.

关键词： Carbon steel Corrosion inhibition Adsorption Arylthiophene derivatives Polarization electrochemical frequency modulation

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Mesenchymal stem cells transplantation attenuates experimentally induced brain injury after neonatal hypoxia by different two routes of administrations

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BIOCelL 2019年第1期43卷 21-28页

作者： Nesrine EBRAHIM Eman EHSAN Eman abd el GHANY Dina SABRY ashraf SHAMAA Histology and Cell Biology Department Faculty of MedicineBenha UniversityBenhaEgypt Pediatrics Department Faculty of MedicineCairo UniversityGizaEgypt Medical Biochemistry and molecular biology Department Faculty of MedicineCairo UniversityGizaEgypt Surgical and Radiology Department Faculty of Veterinary MedicineCairo UniversityGizaEgypt

The neonatal hypoxic-ischemic encephalopathy(HIE)is an important cause of neurological morbidity and mortality in *** therapy is considered a promising method for treating severe neurological disorders such as this *** cells have the capacity for self-renewal and differentiation into certain cell *** present study was aimed to find out the most beneficial route of bone marrow-derived mesenchymal stem cells(BMSCs)administration for the attenuation of experimentally induced HIE in neonatal *** neonatal rats were divided randomly into four *** 1:control *** 2:rats were exposed to bilateral ligation of cephalic *** 3:rats were exposed to bilateral ligation of cephalic arteries and then underwent intravenous(IV)BMSC *** 4:rats were exposed to bilateral ligation of cephalic arteries and then underwent intracerebroventricular(ICV)BMSC *** animals were evaluated by(a)neurobehavioral tests;(b)histopathology,i.e.,histological and immuno-histochemical studies;and(3)gene expression *** BMSC treated groups(3 and 4)showed improvement in neurobehavioral tests,histopathological studies,and gene expression,as compared to non-injected lesioned rats(Group 2)with better improvement in Group 4(ICV injections)than in Group 3(IV injections).

关键词： Cerebral cortex Neonatal hypoxic ischemia Stem cells

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