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Summarizing the evidence for robotic-assisted bladder neck reconstruction: Systematic review of patency and incontinence outcomes

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Asian Journal of Urology 2024年第3期11卷 341-347页

作者： Tenny R.Zhang ashley.alford Lee C.Zhao Department of Urology NewYork-Presbyterian Hospital/Weill Cornell MedicineNew YorkNYUSA Department of Urology NYU Langone Medical CenterNew YorkNYUSA

Objective:Bladder neck contracture and vesicourethral anastomotic stenosis are difficult to manage endoscopically,and open repair is associated with high rates of *** recent years,there have been increasing reports of robotic-assisted bladder neck reconstruction in the ***,existing studies are small,heterogeneous case *** objective of this study was to perform a systematic review of robotic-assisted bladder neck reconstruction to better evaluate patency and incontinence ***:We performed a systematic review of PubMed from first available date to May 2023 for all studies evaluating robotic-assisted reconstructive surgery of the bladder neck in adult *** in non-English,author replies,editorials,pediatric-based studies,and reviews were *** of interest were patency and incontinence rates,which were pooled when ***:After identifying 158 articles on initial search,we included only ten studies that fit all aforementioned criteria for robotic-assisted bladder neck *** were case series published from March 2018 to March 2022 ranging from six to 32 men,with the median follow-up of 5e23 months.A total of 119 patients were included in our analysis.A variety of etiologies and surgical techniques were *** rates ranged from 50%to 100%,and pooled patency was 80%(95/119).De novo incontinence rates ranged from 0%to 33%,and pooled incontinence was 17%(8/47).Our findings were limited by small sample sizes,relatively short follow-ups,and heterogeneity between studies.

关键词： Bladder neck Continence Incontinence Patency Posterior urethra Reconstructive surgery Robotic surgery Stenosis Stricture Surgical outcome

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Climate refugia along Lake Superior’s shores:disjunct arctic-alpine plants rely on cool shoreline temperatures but are restricted to highly exposed habitat under climate warming

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Journal of Plant Ecology 2024年第4期17卷 23-41页

作者： ashley Hillman Scott E.Nielsen Department of Renewable Resources University of AlbertaEdmontonAB T6G 2R3Canada

Climate refugia can serve as a remnant habitat or stepping stones for species dispersal under climate *** largest freshwater lake by surface area,Lake Superior,USA and Canada,serves as a model system for understanding cooling-mediated local refugia,as its cool water temperatures and wave action have maintained shoreline habitats suitable for southern disjunct populations of arctic-alpine plants since ***,we seek to explain spatial patterns and environmental drivers of arctic-alpine plant refugia along Lake Superior’s shores,and assess future risk to refugia under moderate(+3.5℃)and warmest(+5.7℃)climate warming ***,we examined how the interactive effects of summer surface water temperatures and wind affected onshore temperatures,resulting in areas of cooler ***,we developed an ecological niche model for the presence of disjunct arctic-alpine refugia(pooling 1253 occurrences from 58 species)along the lake’s ***,we fit species distribution models for 20 of the most common arctic-alpine disjunct species and predicted presence to identify refugia ***,we used the two climate warming scenarios to predict changes in the presence of refugia and disjunct *** type,elevation above water,inland distance,July land surface temperature from MODIS/Terra satellite and near-shore depth of water were the best predictors of disjunct ***,we predicted 2236 km of the shoreline(51%)as disjunct refugia habitat for at least one species under current conditions,but this was reduced to 20% and 7% with moderate(894 km)and warmest(313 km)climate change projections.

关键词： climate refugia disjunct populations lake effect Lake Superior species distribution models

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Olfactory immune response to SARS-CoV-2

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Cellular & Molecular Immunology 2024年第2期21卷 134-143页

作者： Sebastian A.Wellford E.ashley Moseman Department of Integrative Immunobiology Duke University School of MedicineDurhamNCUSA

Numerous pathogens can infect the olfactory tract,yet the pandemic caused by SARS-CoV-2 has strongly emphasized the importance of the olfactory mucosa as an immune *** in the nasal passages,the olfactory mucosa is directly exposed to the environment to sense airborne odorants;however,this also means it can serve as a direct route of entry from the outside world into the *** a result,olfactotropic infections can have serious consequences,including dysfunction of the olfactory system,CNS invasion,dissemination to the lower respiratory tract,and transmission between *** research has shown that a distinctive immune response is needed to protect this neuronal and mucosal tissue.A better understanding of innate,adaptive,and structural immune barriers in the olfactory mucosa is needed to develop effective therapeutics and vaccines against olfactotropic microbes such as ***,we summarize the ramifications of SARS-CoV-2 infection of the olfactory mucosa,review the subsequent immune response,and discuss important areas of future research for olfactory immunity to infectious disease.

关键词： Mucosal immunology Neuroimmunology Infectious Disease Sars-CoV-2

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Simulation-based assessment for the emergency medicine milestones: a national survey of simulation experts and program directors

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World Journal of Emergency Medicine 2024年第4期15卷 301-305页

作者： Afrah A Ali ashley Crimmins Hegang Chen Danya Khoujah Department of Emergency Medicine University of Maryland School of MedicineBaltimore 21201USA Department of Epidemiology and Public Health University of Maryland School of MedicineBaltimore 21201USA Department of Emergency Medicine AdventHealth TampaTampa 33606USA

The focus of outcome-based education has shifted from the process of training to the end“product”of *** has necessitated a reframing of the teaching,learning,and ***,in 2013,the Accreditation Council for Graduate Medical Education(ACGME)implemented the educational milestones for all accredited residencies and fellowship programs.[1]The milestones have been described as“developmentally based,specialty-specific achievements that residents are expected to demonstrate at established intervals as they progress through training.”[1]Milestones are based on the six core competencies established by the ACGME and American Board of Medical Specialties(ABMS),which consist of medical knowledge(MK),patient care(PC),interpersonal and communication skills(ICS),practice-based learning and improvement(PBLI),professionalism(PROF),and systems-based practice(SBP).[2,3]ACGME,in conjunction with the American Board of Emergency Medicine(ABEM),drafted 23 detailed subcompetencies relevant to emergency medicine(EM).[4]

关键词： Miles milestone education

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Understanding the oxidation chemistry of Ti_(3)C_(2)T_(x)(MXene)sheets and their catalytic performances

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Journal of Energy Chemistry 2024年第1期88卷 437-445,I0010页

作者： Suvdanchimeg Sunderiya Selengesuren Suragtkhuu Solongo Purevdorj Tumentsereg Ochirkhuyag Munkhjargal Bat-Erdene Purevlkham Myagmarsereejid ashley DSlattery Abdulaziz SRBati Joseph GShapter Dorj Odkhuu Sarangerel Davaasambuu Munkhbayar Batmunkh Department of Chemistry Division of Natural SciencesSchool of Arts and SciencesNational University of MongoliaUlaanbaatar 14200Mongolia Queensland Micro-and Nanotechnology Centre School of Environment and ScienceGriffith UniversityNathan campusBrisbaneQueensland 4111Australia Department of Physics Incheon National UniversityIncheon 22012Republic of Korea Australian Institute for Bioengineering and Nanotechnology The University of QueenslandSt LuciaBrisbaneQueensland 4072Australia Adelaide Microscopy The University of AdelaideAdelaideSouth Australia 5005Australia Centre for Organic Photonics&Electronics School of Chemistry and Molecular BiosciencesThe University of QueenslandSt LuciaBrisbaneQueensland 4072Australia

Transition metal carbides and nitrides(MXenes)nanosheets are attractive two-dimensional(2D)materials,but they suffer from oxidation/degradation issues during storage and/or applications due to their sensitivity to water and *** the great research progress,the exact oxidation kinetics of Ti_(3)C_(2)T_(x)(MXene)and their final products after oxidation are not fully ***,we systematically tracked the oxidation process of few-layer Ti_(3)C_(2)T_(x) nanosheets in an aqueous solution at room temperature over several *** also studied the oxidation effects on the electrocatalytic properties of Ti_(3)C_(2)T_(x) for hydrogen evolution reaction and found that the overpotential to achieve a current density of 10 mA cm^(-2)increases from 0.435 to 0.877 V after three weeks of degradation,followed by improvement to stabilized values of around 0.40 V after eight *** results suggest that severely oxidized MXene could be a promising candidate for designing efficient *** to our detailed experimental characterization and theoretical calculations,unlike previous studies,black titanium oxide is formed as the final product in addition to white Ti(IV)oxide and disordered carbons after the complete oxidation of Ti_(3)C_(2)T_(x).This work presents significant advancements in better understanding of 2D Ti_(3)C_(2)T_(x)(MXene)oxidation and enhances the prospects of this material for various applications.

关键词： 2D materials MXene Chemical degradation Catalysis Hydrogen evolution reaction

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海藻泛滥为大西洋岸边的海藻寻求创新用途

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空中英语教室（高级版．彭蒙惠英语） 2024年第7期 28-29,46,47页

作者： ashley Miznazi 不详

海藻一旦堆积在南佛罗里达州的海滩上,就会带来各种各样的问题。它们散发臭味、破坏景观,而且运往垃圾掩埋场的费用又很高,但这在目前却是唯一可行的处理方案。也许有一天,一吨马尾藻可能会物有所值,即使不比黄金,也可能作为肥料。把海... 详细信息

海藻一旦堆积在南佛罗里达州的海滩上,就会带来各种各样的问题。它们散发臭味、破坏景观,而且运往垃圾掩埋场的费用又很高,但这在目前却是唯一可行的处理方案。也许有一天,一吨马尾藻可能会物有所值,即使不比黄金,也可能作为肥料。把海藻转变为植物饲料是迈阿密戴德县正在考虑的六项提议之一,也是该县努力找寻解决海藻激增现象新方法的一部分,科学家们预计气候变化只会导致这种现象持续恶化。

关键词：马尾藻海藻植物饲料物有所值气候变化佛罗里达州迈阿密大西洋

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中国美食,海外崛起

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疯狂英语（新读写） 2024年第1期 14-16,74页

作者： ashley Strickland 不详

中国的许多美食在国外备受欢迎,这一现象不仅反映出了中国传统美食的独特风味,更反映出了中国文化的多样性和丰富性。

关键词：传统美食独特风味文化的多样性丰富性

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猫头鹰迷在哪里

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小哥白尼（野生动物） 2024年第4期 4-7页

作者： ashley Cooper(图) 视觉中国

你喜欢猫头鹰吗?我猜多半是喜欢的,对吧?虽然你可能没有亲眼见过猫头鹰,但一说起猫头鹰,“夜猫子”“捕鼠能手”“不祥的鸟”“妇好鸮尊”等词汇,总有那么一两个在你脑中闪回。猫头鹰嘛,充满了传奇。

关键词：猫头鹰闪回词汇

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Hand Gesture-based Artificial Neural Network Trained Hybrid Human–machine Interface System to Navigate a Powered Wheelchair

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Journal of Bionic Engineering 2021年第5期18卷 1045-1058页

作者： ashley Stroh Jaydip Desai Department of Biomedical Engineering Wichita State UniversityWichitaKS 67260USA

Individuals with cerebral palsy and muscular dystrophy often lack fine motor control of their fingers which makes it difficult to control traditional powered wheelchairs using a *** have shown the use of surface electromyography to steer powered wheelchairs or automobiles either through simulations or gaming ***,these studies significantly lack issues with real world scenarios such as user’s safety,real-time control,and efficiency of the controller *** purpose of this study was to design,evaluate,and implement a hybrid human–machine interface system for a powered wheelchair that can detect human intent based on artificial neural network trained hand gesture recognition and navigate a powered wheelchair without colliding with objects around the *** Conjugate Gradient(SCG),Bayesian Regularization(BR),and Levenberg Marquart(LM)supervised artificial neural networks were trained in offline testing on eight participants without disability followed by online testing using the classifier with highest *** Regularization architecture showed highest accuracy at 98.4%across all participants and hidden *** participants successfully completed the path in an average of 5 min and 50 s,touching an average of 22.1%of the *** proposed hybrid system can be implemented to assist people with neuromuscular disabilities in near future.

关键词： Electromyography,Artificial neural network,Hybrid control,Powered wheelchair Assistive technology,Hand gesture recognition

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Pediatric perspectives on treating uncommon genotypes of hepatitis C in the United States

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Asian Pacific Journal of Tropical Medicine 2021年第8期14卷 375-377页

作者： Vorada Sakulsaengprapha Mary Kay alford Wikrom Karnsakul Johns Hopkins University School of Medicine BaltimoreMarylandUSA Pediatric Liver Center Department of Pediatric GastroenterologyHepatology and NutritionJohns Hopkins University School of MedicineBaltimoreMarylandUSA

Rationale:Hepatitis C in the pediatric population is a large health burden *** its diverse genotypes as well as genotypic subtypes,there is a discrepancy in the genotypes used in research compared to their *** genotype 6 which is endemic to South China and Southeast Asia comprises approximately one-third of all HCV infections worldwide,but make up a minority of cases studied in HCV *** concerns:We report a case of HCV-6 seen in an 11-yearold Burmese immigrant to the *** describe the new direct acting antiviral treatment guidelines for pediatrics with HCV genotype ***:The patient completed a 12-week course of ledipasvir/sofosbuvir(90 mg/400 mg),per FDA weight-based recommendations for treatment-naive HCV genotypes 4-6,without any ***:The patient was treated successfully with an undetectable HCV viral load one month after treatment ***:HCV-6,although previously uncommon in the U.S.,is becoming more *** guidelines include the use of direct acting antivirals,which have been proven effective for *** on barriers to care in the immigrant population as well as the value of HCV genotyping are also discussed.

关键词： Hepatitis C Genotype 6 Pediatrics Direct acting antivirals Immigrant health Refugee health

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