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河南科学 2011年第8期29卷 907-909页

作者：薛宝玉赵俊宏樊燕鸽李文锋 keith b.Dillon 河南省科学院化学研究所郑州450002 Chemistry Department University of DurhamDurham DH1 3LEUK

通过四氯化物ECl(4E是Si,Ge,Sn或As)和三氯化砷AsCl3分别与ArLi,Ar’Li或Ar"Li反应首先合成了10种新的主族元素化合物R1-2ECl1-2,其中R是2,4,6-(CF3)3C6H(2Ar),2,6-(CF3)2C6H3(Ar’)或2,4-(CF3)3C6H(3Ar");Ar,Ar’和Ar"均是大的吸电子... 详细信息

关键词：主族元素化合物吸电子取代基元素分析

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复合微量营养素补充剂对北京市成人血和尿营养素水平的影响

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中华临床营养杂志 2011年第4期19卷 227-231页

作者：李可基元香南杜芳伟 Yumei LIN Mei LI 黄晓明 Randolph R. keith 北京大学公共卫生学院营养与食品卫生系 100191 安利（中国）研发中心北京100191 美国纽崔莱健康研究所广州510730

目的探讨复合微量营养素补充剂对健康成人体内营养素水平的影响。方法选择北京市152名推荐食谱问卷得分低于12分的健康成年人作为研究对象，采用随机数字表法分为安慰剂组和补充剂组，每组76名。两组分别服用安慰剂和复合微量营养素补... 详细信息

目的探讨复合微量营养素补充剂对健康成人体内营养素水平的影响。方法选择北京市152名推荐食谱问卷得分低于12分的健康成年人作为研究对象，采用随机数字表法分为安慰剂组和补充剂组，每组76名。两组分别服用安慰剂和复合微量营养素补充剂。8周后检测受试者血浆及尿液中营养素浓度的变化情况。并于研究第56天同时给两组受试者服用复合微量营养素补充剂，观察服药前和服药后2 h血浆营养素水平变化。结果安慰剂组有3例失访，失访率为5.7%。服用复合微量营养素补充剂8周后，补充剂组的血浆α-生育酚［（18.23±0.82）比（14.55±0.73）μmol/L］、β-胡萝卜素［（4.28±0.29）比（2.38±0.24）μmol/L］、维生素C［（42.65±2.11）比（27.49±1.76）μmol/L］、b6［（323.51±15.88）比（69.43±10.47）nmol/L］和b12浓度［（1005.27±23.00）比（796.85±35.57）pmol/L］，尿维生素b1［（899.24±70.73）比（174.42±13.38）μg/g·Cr］和b2水平［（3227.68±330.04）比（259.10±33.33）μg/g·Cr］，及红细胞叶酸水平［（720.09±21.33）比（633.17±28.75）nmol/L］均明显高于安慰剂组（P均=0.0000），血浆γ-生育酚浓度明显低于安慰剂组［（2.18±0.13）比（2.87±0.26）μmol/L，P=0.0001］。服用复合微量营养素补充剂2 h后，补充剂组的血浆维生素C水平明显高于安慰剂组［（54.53±2.43）比（23.02±1.77）μmol/L，P=0.0000］。结论服用复合微量营养素补充剂可改变健康成人体内的营养素水平，但其意义有待进一步研究探讨。

关键词：复合微量营养素补充剂营养素中国成人

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基于小波方法的粗糙壁内层湍流的多尺度分析

基于小波方法的粗糙壁内层湍流的多尺度分析

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第十二届全国流体力学学术会议

作者：柳婉婷 keith Ngan 华中科技大学航空航天学院香港城市大学

受长方体阵列影响的边界层湍流是一种典型的粗糙壁湍流,因其内层湍流在城市边界层中的应用而受到广泛关注。尽管障碍物造成了空间相关的湍流运动,这种不均匀性对湍流基本特征(如湍流结构)的影响仍然缺少研究,这导致了其内层湍流模型的... 详细信息

受长方体阵列影响的边界层湍流是一种典型的粗糙壁湍流,因其内层湍流在城市边界层中的应用而受到广泛关注。尽管障碍物造成了空间相关的湍流运动,这种不均匀性对湍流基本特征(如湍流结构)的影响仍然缺少研究,这导致了其内层湍流模型的缺失。本文引入了具有局部变换的小波方法来研究长方体阵列如何影响湍流结构以及湍动能的生成与传递。首先,湍动能的小波表示展现了不同尺度湍流的空间分布(图1),得到了不同区域的湍流能谱。其次,能量生成谱(production spectra)与能量传输谱(transfer spectra)展示了湍动能的生成与传递的尺度和长方体的空间尺度相关。例如,交错长方体阵列内的湍流的能量生成谱在其周期尺度上最大化(图2(a)),而其能量传输谱展现了其水平方向上缺少能量级联energy(cascade)现象,即湍流通过非线性项在大尺度运动中获得湍动能(图2(b))。最后,通过基于小波滤波器,小尺度湍流产生的湍粘度的空间分布也得到了量化,显现出它们在障碍物内层远高于外层的特征。本研究发现,相较于光滑壁湍流,粗糙壁湍流更依赖于特定的空间尺度,且具有更强的空间局部性,这些结论为粗糙壁内层湍流建模提供了理论基础。

关键词：粗糙壁湍流湍动能小波方法多尺度分析湍粘度

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态度决定一切

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作者： (美)凯斯·哈瑞尔(keith Harrell)

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Surface-Driven High-Pressure Processing

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Engineering 2018年第3期4卷 311-320页

作者： keith E. Gubbins Kai Gu Liangliang Huang Yun Long J. Matthew Mansell Erik E. Santiso Kaihang Shi Malgorzata Sliwifiska-bartkowiak Deepti Srivastava Department of Chemical and biomolecular Engineering North Carolina State University Raleigh NC 27695-7905 USA Department of Chemistry Zhejiang University Hangzhou 310027 China School of Chemical Biological and Materials Engineering The University of Oklahoma Norman OK 73019 USA Department of Chemical and biomolecular Engineering National University of Singapore Singapore 117585 Singapore Faculty of Physics Adam Mickiewicz University in Poznan Poznaan 61-614 Poland

The application of high pressure favors many chemical processes, providing higher yields or improved rates in chemical reactions and improved solvent power in separation processes, and allowing activation barriers to be overcome through the increase in molecular energy and molecular collision rates. High pressures-up to millions of bars using diamond anvil cells-can be achieved in the laboratory, and lead to many new routes for chemical synthesis and the synthesis of new materials with desirable thermody- namic, transport, and electronic properties. On the industrial scale, however, high-pressure processing is currently limited by the cost of compression and by materials limitations, so that few industrial processes are carried out at pressures above 25 MPa. An alternative approach to high-pressure processing is pro- posed here, in which very high local pressures are generated using the surface-driven interactions from a solid substrate. Recent experiments and molecular simulations show that such interactions can lead to local pressures as high as tens of thousands of bars （1 bar=1×10^5 Pa）, and even millions of bars in some cases. Since the active high-pressure processing zone is inhomogeneous, the pressure is different in dif- ferent directions. In many cases, it is the pressure in the direction parallel to the surface of the substrate （the tangential pressure） that is most greatly enhanced. This pressure is exerted on the molecules to be processed, but not on the solid substrate or the containing vessel. Current knowledge of such pressure enhancement is reviewed, and the possibility of an alternative route to high-pressure processing based on surface-driven forces is discussed. Such surface-driven high-pressure processing would have the advantage of achieving much higher pressures than are possible with traditional bulk-phase processing, since it eliminates the need for mechanical compression. Moreover, no increased pressure is exerted on the containing vessel fo

关键词： Confinement High pressure High pressure phase High pressure reaction High pressure manufacture High pressure chemical processing

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Pancreatic exocrine insufficiency after pancreaticoduodenectomy: Current evidence and management

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World Journal of Gastrointestinal Pathophysiology 2020年第2期11卷 20-31页

作者： Adithya M Pathanki Joseph A Attard Elizabeth bradley Sarah Powell-brett bobby V M Dasari John R Isaac keith J Roberts Nikolaos A Chatzizacharias Department of HPb and Liver Transplantation Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152THUnited Kingdom Department of Nutrition and Dietetics Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152THUnited Kingdom

Pancreaticoduodenectomy(PD)is the commonest procedure performed for pancreatic *** exocrine insufficiency(PEI)may be caused or exacerbated by surgery and remains underdiagnosed and *** aim of this review was to ascertain the incidence of PEI,its consequences and management in the setting of PD for indications other than chronic pancreatitis.A literature search of databases(MEDLINE,EMbASE,Cochrane and Scopus)was carried out with the MeSH terms“pancreatic exocrine insufficiency”and“Pancreaticoduodenectomy”.Studies that analysed PEI and its complications in the setting of PD for malignant and benign disease were *** reporting PEI in the setting of PD for chronic pancreatitis,conference abstracts and reviews were *** incidence of PEI approached 100%following PD in some *** pre-operative incidence varied depending on the characteristics of the patient cohort and it was higher(46%-93%)in series where pancreatic cancer was the predominant indication for *** was also recorded with regards to the method used for the diagnosis and evaluation of pancreatic function and *** enzyme replacement therapy is the mainstay of the *** is common and remains undertreated after *** studies are required for the identification of a welltolerated,reliable and reproducible diagnostic test in this setting.

关键词： Pancreatic exocrine insufficiency Pancreaticoduodenectomy Pancreatic enzyme replacement therapy Pancreatic cancer Malabsorption Steatorrhoea

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美国最佳新闻作品集 2001

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2003年

作者：（美）基思·伍兹（keith Woods）编李隽琼等译

全书收录了2001年度荣获“美国报纸主编协会杰出新闻写作奖“的获奖作品中，分为无截稿时间限制新闻写作奖，评论奖，族裔多样性报道奖，社论写作奖等各奖项的新闻作品。

ISBN: (数字)7501161178

ISBN: (纸本)7501161178

关键词：新闻作品集美国现代

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人类的自我发现之旅

人类的自我发现之旅

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作者： (加)基思·奥特利(keith Oatley)

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剑桥心理学史

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2021年

作者： (美)詹姆斯·F.布伦南(James F. brennan)，(美)基思·A.霍德( keith A. Houde)

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SIMAP500: A novel risk score to identify recipients at higher risk of hepatocellular carcinoma recurrence following liver transplantation

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World Journal of Transplantation 2024年第3期14卷 132-143页

作者： Amr Alnagar Nekisa Zakeri Konstantinos Koilias Rosemary E Faulkes Rachel brown Owen Cain M Thamara P R Perera keith J Roberts Rebeca Sanabria-Mateos David C bartlett Yuk Ting Ma Shivan Sivakumar Shishir Shetty Tahir Shah bobby V M Dasari Department of HbP and Liver Transplantation Surgery Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152GWUnited Kingdom Centre for Liver Research Institute of Biomedical ResearchBirmingham B152TTUnited Kingdom Department of Hepatology Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152GWUnited Kingdom Department of Pathology University Hospitals Birmingham NHS Foundation TrustBirmingham B152GWUnited Kingdom Department of Oncology Queen Elizabeth HospitalUniversity Hospitals of BirminghamBirmingham B152GWUnited Kingdom

bACKGROUND Recurrence of hepatocellular carcinoma(HCC)following liver transplantation(LT)has a devastating influence on recipients’survival;however,the risk of recur-rence is not routinely *** stratification is vital with a long LT waiting time,as that could influence the recurrence despite strict listing *** This study aims to identify predictors of recurrence and develop a novel risk pre-diction score to forecast HCC recurrence following *** A retrospective review of LT for HCC recipients at University Hospitals bir-mingham between July 2011 and February *** and multivariate analyses were performed to identify recurrence predictors,based on which the novel SIMAP500(satellite nodules,increase in size,microvascular invasion,AFP>500,poor differentiation)risk score was *** 234 LTs for HCC were performed with a median follow-up of 5.3 *** developed in 25 patients(10.7%).On univariate analyses,RETREAT score>3,α-fetoprotein(AFP)at listing 100-500 and>500,bridging,increased tumour size between imaging at the listing time and explant histology,increase in the size of viable tumour between listing and explant,presence of satellite nodules,micro-and macrovascular invasion on explant and poor differentiation of tumours were significantly associated with recurrence,based on which,the SIMAP500 risk score is *** SIMAP500 demonstrated an excellent predictive ability(c-index=0.803)and outper-formed the RETREAT score(c-index=0.73).SIMAP500 is indicative of the time to disease *** SIMAP500 risk score identifies the LT recipients at risk of HCC *** stratification allows patient-centric post-transplant surveillance *** validation of the score is recommended.

关键词： Liver transplantation Hepatocellular carcinoma Recurrence Survival

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