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Virtual Staining,Segmentation,and Classification of Blood Smears for Label-Free Hematology Analysis

Biomedical Engineering Frontiers 2022年第1期3卷 309-322页

作者： Nischita Kaza ashkan ojaghi Francisco E.Robles School of Electrical and Computer Engineering Georgia Institute of TechnologyAtlantaGeorgiaUSA Wallace H.Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory UniversityAtlantaGeorgiaUSA

Objective and Impact *** present a fully automated hematological analysis framework based on single-channel(single-wavelength),label-free deep-ultraviolet(UV)microscopy that serves as a fast,cost-effective alternative to conventional hematology *** analysis is essential for the diagnosis and monitoring of several diseases but requires complex systems operated by trained personnel,costly chemical reagents,and lengthy ***-free techniques eliminate the need for staining or additional preprocessing and can lead to faster analysis and a simpler *** this work,we leverage the unique capabilities of deep-UV microscopy as a label-free,molecular imaging technique to develop a deep learning-based pipeline that enables virtual staining,segmentation,classification,and counting of white blood cells(WBCs)in single-channel images of peripheral blood *** train independent deep networks to virtually stain and segment grayscale images of *** segmented images are then used to train a classifier to yield a quantitative five-part WBC *** virtual staining scheme accurately recapitulates the appearance of cells under conventional Giemsa staining,the gold standard in *** trained cellular and nuclear segmentation networks achieve high accuracy,and the classifier can achieve a quantitative five-part differential on unseen test *** proposed automated hematology analysis framework could greatly simplify and improve current complete blood count and blood smear analysis and lead to the development of a simple,fast,and low-cost,point-of-care hematology analyzer.

关键词： networks classifier Blood

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Static and Dynamic Pull-In Instability of Nano-Beams Resting on Elastic Foundation Based on the Nonlocal Elasticity Theory

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Chinese Journal of Mechanical Engineering 2017年第2期30卷 385-397页

作者： HAMID M Sedighi ashkan Sheikhanzadeh Mechanical Engineering Department Faculty of EngineeringShahid Chamran University of Ahvaz Departmentof Mechanical Engineering Najafabad BranchIslamic Azad Univesity

This paper provides the static and dynamic pullin behavior of nano-beams resting on the elastic foundation based on the nonlocal theory which is able to capture the size effects for structures in micron and sub-micron scales. For this purpose, the governing equation of motion and the boundary conditions are driven using a variational approach. This formulation includes the influences of fringing field and intermolecular forces such as Casimir and van der Waals forces. The differential quadrature （DQ） method is employed as a high-order approximation to discretize the governing nonlinear differential equation, yielding more accurate results with a Considerably smaller number of grid points. In addition, a powerful analytical method called parameter expansion method （PEM） is utilized to compute the dynamic solution and frequency-amplitude relationship. It is illustrated that the first two terms in series expansions are sufficient to produce an acceptable solution of the mentioned structure. Finally, the effects of basic parameters on static and dynamic pull-in insta- bility and natural frequency are studied.

关键词： Static and dynamic pull·in voltages Size dependent Nonlocal theory Euler·Bernoulli beam model Differential quadrature method Parameter Expansion method

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Full-Quantum Simulation of Graphene Self-Switching Diodes

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Chinese Physics Letters 2019年第6期36卷 53-56页

作者： ashkan Horri Rahim Faez Department of Electrical Engineering Arak Branch Islamic Azad University Arak Department of Electrical Engineering Tehran Sharif University of Technology

We present a quantum study on the electrical behavior of the self-switching diode(SSD). Our simulation is based on non-equilibrium Green's function formalism along with an atomistic tight-binding model. Using this method,electrical characteristics of devices, such as turn-on voltage, rectification ratio, and differential resistance, are investigated. Also, the effects of geometrical variations on the electrical parameters of SSDs are simulated. The carrier distribution inside the nano-channel is successfully simulated in a two-dimensional model under zero,reverse, and forward bias conditions. The results indicate that the turn-on voltage, rectification ratio, and differential resistance can be optimized by choosing appropriate geometrical parameters.

关键词： Full-Quantum Simulation Graphene Self-Switching Diodes

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Experimental investigation into effects of the natural polymer and nanoclay particles on the EOR performance of chemical flooding in carbonate reservoirs

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Petroleum Science 2024年第2期21卷 951-961页

作者： Amir Mohammad Zamani ashkan Moslemi Kamran Hassani Department of Petroleum Engineering Islamic Azad University Science and Research BranchTehranIran Institute of Petroleum Engineering University of TehranTehranIran

This paper aims to investigate the tragacanth gum potential as a natural polymer combined with natural clay mineral(montmorillonite,kaolinite,and illite)nanoparticles(NPs)to form NP-polymer suspension for enhanced oil recovery(EOR)in carbonate *** gravimetric analysis(TGA)tests were conducted initially in order to evaluate the properties of tragacanth ***,scanning electron microscopy(SEM)and energy-dispersive X-ray(EDX)tests were used to detect the structure of clay *** various scenarios,the effects of natural NPs and polymer on the wettability alteration,interfacial tension(IFT)reduction,viscosity improvement,and oil recovery were investigated through contact angle system,ring method,Anton Paar viscometer,and core flooding tests,*** entire experiment was conducted at 25,50,and 75℃,*** to the experimental results,the clay minerals alone did not have a significant effect on viscosity,but the addition of minerals to the polymer solution leads to the viscosity enhancement remarkably,resulting mobility ratio *** clay NPs,the combination of natural polymer and kaolinite results in increased viscosity at all *** wettability alteration was also observed in the case of natural polymer and illite *** in combination with natural polymer showed an ability in reducing ***,the results of displacement experiments revealed that the combination of natural polymer and kaolinite could be the best option for EOR due to its substantial ability to improve the recovery factor.

关键词： Chemical flooding Tragacanth gum Clay nanoparticle Wettability IFT

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Sulfamic acid as a reusable and green catalyst for efficient and simple synthesis of 2-substituted-2,3-dihydroquinazolin-4(1H)-ones in water or methanol

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Chinese Chemical Letters 2011年第11期22卷 1317-1320页

作者： Amin Rostami ashkan Tavakoli Department of Chemistry Faculty of Science University of KurdistanSanandaj ***Iran

A series of 2,3-dihydroquinazolin-4（1H）-ones have been synthesized in good to excellent yields through direct cyclocondensation of anthranilamide and aryl aldehydes or ketones in water or methanol under mild *** reaction was efficiently promoted by 10 mol%sulfamic acid（SA,H_2NSO_3H） and the catalyst could be recovered easily after the reactions and reused without evident loss of reactivity.

关键词： Sulfamic acid Catalyst Anthranilamide Aldehyde Ketone 2 3-Dihydroquinazolin-4(1H)-ones

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On Generalization of Cycles and Chordality to Clutters from an Algebraic Viewpoint

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Algebra Colloquium 2017年第4期24卷 611-624页

作者： ashkan Nikseresht Rashid Zaare-Nahandi Department of Mathematics Institute for Advanced Studies in Basic Sciences P.O. Box 45195-1159 Zanjan Iran

In this paper, we study the notion of chordality and cycles in clutters from a commutative algebraic point of view. The corresponding concept of chordality in commutative algebra is having a linear resolution. We mainly consider the generalization of chordality proposed by Bigdeli et al. in 2017 and the concept of cycles introduced by Can- non and Faridi in 2013, and study their interrelations and algebraic interpretations. In particular, we investigate the relationship between chordality and having linear quotients in some classes of clutters. Also, we show that if e is a clutter such that （） is a vertex decomposable simplicial complex or I（） is squarefree stable, then is chordal.

关键词： chordal clutter squarefree monomial ideal linear resolution cycle simplicialcomplex

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Synthesis and characterization of conducting polyaniline nanocomposites containing ZnO nanorods

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Progress in Natural Science:Materials International 2012年第4期22卷 273-280页

作者： Amir Mostafaei ashkan Zolriasatein Faculty of Materials Engineering Sahand University of TechnologyTabrizIran Advanced Materials and Nanotechnology Research Laboratory Faculty of Mechanical EngineeringK.N.Toosi University of TechnologyTehranIran

Polyaniline (PANI) based nanocomposites filled with ZnO nanorods were prepared by the chemical oxidative method of the aniline in acid medium with ammonium peroxydisulphate (APS) as an oxidant. The composition, morphology and structure of the polymer and the nanocomposites were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), UV-vis spectroscopy and electrical conductivity. The characteristic FTIR peaks of PANI were found to shift to higher or lower wave number in PANI-ZnO composites due to formation of H-bonding. Different amounts of ZnO nanorods were used to verify this effect on the characteristics of the synthesized materials. These observed effects have been attributed to interaction of ZnO nanorods with PANI molecular chains. XRD results revealed that the crystallinity of PANI was more pronounced after addition of nanorods, while the intensity of the peaks increased by addition of ZnO nanorods. Electrical conductivity of the PANI-ZnO nanocomposite film was found to be smaller than that of the PANI film. The decrease of electrical conductivity in PANI-ZnO films as compared to PANI was attributed to the interfaces formed between oxygen of ZnO nanorods and hydrogen of PANI. Also, TGA results showed that the decomposition of the nanocomposite was less than that of pure polyaniline which confirms the successful fabrication of products. These conductive polymers can be used in commercial paints as an additive.

关键词： Conductive polymer Polyaniline based nanocomposite ZnO nanorods Chemical synthesis

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Assessment of geochemical and sedimentological characteristics of atmospheric dust in Shiraz,southwest Iran

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Geoscience Frontiers 2020年第3期11卷 783-792页

作者： Amir Karimian Torghabeh Biswajeet Pradhan ashkan Jahandari Department of Earth Sciences Faculty of SciencesShiraz UniversityShirazIran The Centre for Advanced Modeling and Geospatial Information Systems(CAMGIS) Faculty of Engineering and ITUniversity of Technology SydneySydneyNSW2007Australia Department of Energy and Mineral Resources Engineering Sejong UniversityChoongmu-gwan209 Neungdong ro Gwangjin-guSeoul05006South Korea Department of Geology Shahid Bahonar University of KermanKermanIran

Geogenic dust is commonly believed to be one of the most important environmental problems in the Middle *** present study investigated the geochemical characteristics of atmospheric dust particles in Shiraz City(south of Iran).Atmospheric dust samples were collected through a dry collector method by using glass trays at 10 location sites in May *** composition was analysed through inductively coupled plasma optical emission *** data showed that the dustiest days were usually in spring and summer,particularly in April.X-ray diffraction analysis of atmospheric dust samples indicated that the mineralogical composition of atmospheric dust was calcite+dolomite(24%)>palygorskite(18%)>quartz(14%)>muscovite(13%)>albite(11%)>kaolinite(7%)>gypsum(7%)>zircon=anatase(3%).The high occurrence of palygorskite(16%-23%) could serve as a tracer of the source areas of dust storms from the desert of Iraq and Saudi Arabia to the South of *** electron microscopy indicated that the sizes of the collected dust varied from 50 μm to0.8 μm,but 10 μm was the predominant *** atmospheric dust collected had prismatic trigonal-rhombohedral crystals and semi-rounded irregular ***,diatoms were detected in several samples,suggesting that emissions from dry-bed lakes,such as Hoor Al-Azim Wetland(located in the southwest of Iran),also contributed to the dust *** trajectory simulations were performed at the date of sampling by using the NOAA HYSPLIT *** showed that the sources of atmospheric dust in the study area were the eastern area of Iraq,eastern desert of Saudi Arabia,Kuwait and Khuzestan *** Ca/Al ratio of the collected samples(1.14) was different from the upper continental crust(UCC) value(UCC=0.37),whereas Mg/A1(0.29),K/Al(0.22) and Ti/Al(0.07) ratios were close to the UCC value(0.04).This condition favours desert calcisols as the main mineral dust *** of the crustal enrichment factor(EF

关键词： Dust storm Atmospheric dust Heavy metals Diatom Palygorskite Provenance

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Large Signal Circuit Model of Two-Section Gain Lever Quantum Dot Laser

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Chinese Physics Letters 2012年第11期29卷 85-87页

作者： ashkan Horri Seyedeh Zahra Mirmoeini Rahim Faez Young Researchers Club Arak BranchIslamic Azad UniversityArakIran Department of Electrical Engineering Arak BranchIslamic Azad UniversityArakIran Department of Electrical Engineering Sharif University of TechnologyTehranIran

An equivalent circuit model for the design and analysis of two-section gain lever quantum dot(QD)laser is *** model is based on the three level rate equations with two independent carrier populations and a single longitudinal optical *** using the presented model,the effect of gain lever on QD laser performances is *** results of simulation show that the main characteristics of laser such as threshold current,transient response,output power and modulation response are affected by differential gain ratios between the two-sections.

关键词： laser Signal Quantum

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Comparative study of heat transfer and pressure drop for curved-twisted tubes utilized in chemical engineering

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Chinese Journal of Chemical Engineering 2021年第12期34卷 53-64页

作者： Morteza Khoshvaght-Aliabadi Saber Deldar Shafiqur Rehman ashkan Alimoradi Department of Chemical Engineering Shahrood BranchIslamic Azad UniversityShahroodIran Department of Mechanical Engineering Tarbiat Modares UniversityTehranIran Center for Engineering Research The Research InstituteKing Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia Department for Management of Science and Technology Development Ton Duc Thang UniversityHo Chi Minh CityViet Nam Faculty of Applied Sciences Ton Duc Thang UniversityHo Chi Minh CityViet Nam

Increasing importance of heat transfer in chemical engineering science causes that investigation in the field of enhancement techniques is always one of the up-to-date topics for *** the current comparative analysis,the thermal enhancement and friction penalty are explored numerically for curved tubes via twisted *** accomplish this,three common geometries namely helical,serpentine,and Archimedes spiral,are considered at different coil-pitches and twist-pitches as well as five Reynolds numbers in the laminar flow *** results exhibit noticeable enhancements(up to 60%)in the thermal performance of the twisted cases as compared to the smooth *** highest increases are recorded for the serpentine case,followed by the helical and spiral *** is found that these enhancements vary via coil-pitch and *** coil-pitch and twist-pitch augments both heat transfer coefficient and pressure drop in all curved-twisted tubes,however,the effects of twist-pitch are more *** predict Nusselt number and friction factor,new correlations are also *** maximum deviations of the predicted results compared to the simulated data are within±5%.

关键词： Computational fluid dynamics Heat transfer Laminar flow Curved-twisted tubes Comparative study

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