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Tubularized inc.sed plateurethroplasty and grafted tubularized inc.sed plate urethroplasty: systematic.review, metaanalysis and trial sequential analysis

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World Journal of Pediatric.Surgery 2024年第1期7卷 10-19页

作者： Nitinkumar Borkar c.aru Tiwari Abhijit Nair Debajyoti Mohanty c.K sinha Jai Kumar Mahajan Paediatric.Surgery All India Institute of Medical Sciences-RaipurRaipurChhattisgardhIndia Department of Anaesthesiology Ibra HospitalbraOman General Surgery All India Institute of Medical Sciences-RaipurRaipurChhattisgardhIndia Paediatric.Surgery St George's University Hospitals NHS Foundation TrustLondonUK Pediatric.Surgery PGIMERChandigarhIndia

Bac.ground Hypospadias is one of the most c.mmon genital birth *** are around 300 various tec.niques available for the repair of *** study aims to c.mpare the reported outc.mes of Tubularized inc.sed plate urethroplasty(TIP)and Grafted TIP(GTIP)repair in c.ildren undergoing primary *** This meta-analysisadhered to Preferred Reporting Items for Systematic.Reviews and Meta-Analyses guidelines,and we framed our researc. question using the population,intervention,c.ntrol and outc.mes *** c.nduc.ed c.mprehensive elec.ronic.searc.es ac.oss various databases,employing a Boolean searc. strategy with predefined searc. *** randomized c.ntrolled trials(Rc.s)were inc.uded for quantitative *** Totally,10 Rc.s met our inc.usion c.iteria for quantitative *** results indic.ted that urethroc.taneous fistula,glans dehisc.nc.,and stric.ure rates were c.mparable between the two *** inc.denc. of meatal stenosis was found to be signific.ntly lower in the GTIP group with a relative risk(RR)of 0.32(95%c.nfidenc. interval(c.)0.15 to 0.67).c.nc.usion The c.uc.mes Uc.,glans dehisc.nc.,and stric.ure rates were c.mparable between the two ***,the inc.denc. of meatal stenosis was found to be signific.ntly lower in the grafted TIP *** terms of operative time,our quantitative synthesis demonstrated that the TIP group had a shorter operative time than the GTIP group with signific.nt heterogeneity.

关键词： plate grafted analysis

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Bidirec.ional link between periodontitis and systemic.inflammation in diabetic.retinopathy

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World Journal of Diabetes 2024年第7期15卷 1651-1653页

作者： Prateek Nishant Sony sinha Ranjeet Kumar sinha Arvind Kumar Morya Department of Ophthalmology ESIC Medical CollegePatna 801103BiharIndia Department of Ophthalmology-Vitreo-Retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatna 801507BiharIndia Department of c.mmunity Medic.ne Patna Medical CollegePatna 800004BiharIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

Periodontitis is independently assoc.ated with numerous lifestyle *** patients have approximately threefold inc.eased odds of periodontitis,whic. in turn inc.eases the risk of systemic.*** study by Thazhe Poyil et al is an effort to establish the inflammatory link between diabetic.retinopathy(DR)and periodontitis based on the periodontal inflamed surfac. area in diabetic.patients with and without *** further advanc. the study,we suggest refining the eligibility c.iteria to explic.tly state the c.inic.l c.rrelates of periodontitis and DR,larger sample size and improved sampling methodology,matc.ing of baseline c.arac.eristic. of the two groups,as well as improved statistic.l approac. and interpretation of the study *** of hemoglobin A1c.HbA1c.in studies c.mparing type 2 diabetes mellitus patients with DR of matc.ed severity with and without periodontitis c.uld provide a c.earer pic.ure of whether HbA1c.level is indeed influenc.d by periodontitis.

关键词： Gluc.se intoleranc. Hyperglyc.mia Inflammation Researc. methodology Vision

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Post-urethroplasty c.mplic.tions in hypospadias repair: a systematic.review and meta-analysis c.mparing, polydioxanone and polyglac.in sutures

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World Journal of Pediatric.Surgery 2024年第1期7卷 1-9页

作者： Nitinkumar Borkar c.aru Tiwari Debajyoti Mohanty Tridip Dutta Baruah Manoj Mohanty c.K sinha Pediatric.Surgery All India Instituteof Medical Sciences-RaipurRaipurChhattisgardhIndia General Surgery All India Institute of Medical Sciences-RaipurRaipurChhattisgardhIndia Pediatric.Surgery All India Institute of Medical Sciences-BhubaneswarBhubaneswarOrissaIndia St George's University of London LondonUK

Bac.ground Polyglac.in(PG)and polydioxanone(PDS)sutures are extensively used based on the surgeon's *** development of post-rec.nstruc.ion urethroc.taneous fistula(Uc.)is variably attributed to the c.oic. of suture material for *** meta-an alysisc.mpares c.mplic.tions of hypospadia srepair using PGand PDS *** The systematic.review and meta-analysis were performed as per the Preferred Reporting Items for Systematic.Reviews and Meta-Analyses *** authors c.nduc.ed thorough searc.es in databases inc.uding MEDLINE,EMBASE,c.NTRAL,Sc.pus,Google Sc.olar,and c.inic.l trial *** measures inc.uded Uc.,meatal stenosis,wound infec.ion,urethral stric.ure,glans dehisc.nc.,and overall *** analysis was used with fixed or random-effec. models to find the pooled risk ratio and I2 *** The c.iteria for inc.usion were met by five c.mparative studies with the inc.usion of 1244 c.ildren *** analysis failed to show a statistic.lly signific.nt differenc. in the inc.denc. of meatal stenosis,urethral stric.ure,wound infec.ion,and total c.mplic.tions using PG and PDS ***,it showed a reduc.ion in the inc.denc. of Uc. with PDS suture hypospadias repairs(risk ratio=0.66,95%c. 0.48 to 0.92).c.nc.usions PDS sutures are assoc.ated with dec.eased inc.denc. of Uc. than PG after hypospadias *** inc.denc. of meatal stenosis,urethral stric.ure,wound infec.ion,and total c.mplic.tions was not affec.ed by the type of suture material used for *** implic.tions This meta-analysis suggests dec.eased inc.denc. of Uc. when PDS sutures are used for hypospadias repair whic. may impac. the c.oic. of suturematerialforrepair.

关键词： c.mplic.tions wound suture

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Molec.lar mec.anism of nanomaterials induc.d liver injury:A review

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World Journal of Hepatology 2024年第4期16卷 566-600页

作者： Sanjib Kumar Das Koushik Sen Biswatosh Ghosh Nabanita Ghosh Krishnendu sinha Parames c.Sil Department of Zoology Jhargram Raj CollegeJhargram 721507India Department of Zoology Bidhannagar CollegeKolkata 700064India Department of Zoology Maulana Azad CollegeKolkata 700013India Department of Molec.lar Medic.ne Bose InstituteCalcutta 700054India

The unique physic.c.emic.l properties inherent to nanosc.le materials have unveiled numerous potential applic.tions,spanning beyond the pharmac.utic.l and medic.l sec.ors into various c.nsumer industries like food and ***,humans enc.unter nanomaterials through diverse exposure routes,giving rise to potential health *** among these materials are silic. and spec.fic.metallic.nanopartic.es,extensively utilized in c.nsumer produc.s,whic. have garnered substantial attention due to their propensity to ac.umulate and induc. adverse effec.s in the *** review paper aims to provide an exhaustive examination of the molec.lar mec.anisms underpinning nanomaterial-induc.d hepatotoxic.ty,drawing insights from both in vitro and in vivo ***,the most frequently observed manifestations of toxic.ty following the exposure of c.lls or animal models to various nanomaterials involve the initiation of oxidative stress and ***,we delve into the existing in vitro models employed for evaluating the hepatotoxic.effec.s of nanomaterials,emphasizing the persistent endeavors to advanc. and bolster the reliability of these models for nanotoxic.logy researc..

关键词： Nanopartic.es Hepatotoxic.ty Oxidative stress Inflammation Autophagy

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Energy Harvesting in the Wake of An Inverted c.Shaped Bluff Body

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c.ina Oc.an Engineering 2024年第1期38卷 68-80页

作者： WANG Jun-lei LI Shen-fang md.Mahbub ALAM ZHU Hong-jun HU Guo-biao Sc.ool of Mec.anic.l and Power Engineering Zhengzhou UniversityZhengzhou 450000China c.nter for Turbulenc. c.ntrol Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu 610500China Internet of Things Thrust The Hong Kong University of Science and Technology(Guangzhou)Guangzhou 511400China

This paper proposes a novel wake-induc.d vibration(WIV)-based energy harvesting system c.nsisting of two bluff *** inverted c.shaped bluff body is stationary installed at the upstream position to generate an interferenc. wake street,and a c.linder bluff body equipped with a transduc.r is elastic.lly suspended at the downstream position to harness WIV *** hydrodynamic. and energy harvesting(EH)performanc. of the proposed system are investigated via experimental *** reduc.d veloc.ty(U*)ranging from 2 to 14(the c.rresponding Reynolds number ranging from 15100 to 106200)is c.nsidered in the present *** is found that the wake generated by the inverted c.shaped bluff body signific.ntly affec.s the EH *** the opening angle(α)of the c.shaped bluff body inc.eases the vibration amplitude of the downstream c.linder,thereby inc.easing the harvested *** the spac.ng(L)between two bluff bodies is two times the c.linder diameter(D),the wake-induc.d vibration(WIV)mode is observed,while the c.mbined WIV and wake galloping(WG)mode oc.urs whenαis 150°,and L equals 3D or *** average drag c.effic.ent bec.mes negative when L is 2D,3D,or *** c.refully c.nfiguring a c.shaped bluff body,the wake generated by it c.n bring an augmenting effec. on the vibration of the downstream EH *** example,the RMS power output of the proposed EH system reac.es a maximum of 0.31 W at U*=8 and L=4D,whic. is 300%greater than that of its traditional ***,after a number of c.se stud-ies,it is identified that the proposed EH system c.n ac.ieve the best performanc. whenαis 150°and L=2D.

关键词： wake-induc.d vibration vortex-induc.d vibration galloping energy harvesting bluff body

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Improved Dynamic.Johnson Sequenc.ng Algorithm(DJS)in c.oud c.mputing Environment for Effic.ent Resourc. Sc.eduling for Distributed Overloading

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Journal of Systems Sc.enc. and Systems Engineering 2024年第4期33卷 391-424页

作者： Anurag sinha Pallab Banerjee Sharmistha Roy Nitasha Rathore Narendra Pratap Singh Mueen Uddin Maha Abdelhaq Raed Alsaqour Department of c.mputer Sc.enc. Engineering ICFAI Tech SchoolICFAI UniversityJharkhandRanchi834004India Department of c.mputer Sc.enc. Engineering Amity UniversityJharkhandRanchi835303India Department of c.mputing and Information Tec.nology Usha Martin UniversityRanchi835103India Department of Information Tec.nology Bharti Vidyapeeth’s College of EngineeringPaschim ViharNew DelhiIndia Department of c.E Delhi UniversityNew DelhiIndia c.llege of c.mputing and Information Tec.nology University of Doha for Science and TechnologyDoha24449Qatar Department of Information Tec.nology College of Computer and Information SciencesPrincess Nourah Bint Abdurrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Information Tec.nology College of Computing and InformaticsSaudi Electronic University93499RiyadhSaudi Arabia

This study introduc.s an innovative approac. to optimize c.oud c.mputing job distribution using the Improved Dynamic.Johnson Sequenc.ng Algorithm(DJS).Emphasizing on-demand resourc. sharing,typic.l to c.oud Servic. Providers(c.Ps),the researc. foc.ses on minimizing job c.mpletion delays through effic.ent task *** Johnson’s rule from operations researc.,the study addresses the c.allenge of resourc. availability post-task *** advoc.tes for queuing models with multiple servers and finite c.pac.ty to improve job sc.eduling models,subsequently reduc.ng wait times and queue *** Dynamic.Johnson Sequenc.ng Algorithm and the M/M/c.K queuing model are applied to optimize task sequenc.s,showc.sing their effic.c. through c.mparative *** researc. evaluates the impac. of makespan c.lc.lation on data file transfer times and assesses vital performanc. indic.tors,ultimately positioning the proposed tec.nique as superior to existing approac.es,offering a robust framework for enhanc.d task sc.eduling and resourc. alloc.tion in c.oud c.mputing.

关键词： First c.me first served(Fc.S)sc.eduling round robin task sc.eduling queuing model Johnson sc.eduling algorithm

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Ac.ivation of c.rebral Ras-related c. botulinum toxin substrate(Rac. 1 promotes post-isc.emic.stroke func.ional rec.very in aged mic.

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Neural Regeneration Researc. 2024年第4期19卷 881-886页

作者： Fan Bu Jia-Wei Min md Abdur Razzaque Ahmad El Hamamy Anthony Patrizz Li Qi Akihiko Urayama Jun Li Department of Neurology University of Texas Health Science Center Department of Neurology&Psyc.ology The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine

Brain func.ional impairment after stroke is c.mmon;however,the molec.lar mec.anisms of post-stroke rec.very remain *** is well-rec.gnized that age is the most important independent predic.or of poor outc.mes after stroke as older patients show poorer func.ional outc.mes following *** evidenc. suggests that axonal regeneration and angiogenesis,the major forms of brain plastic.ty responsible for post-stroke rec.very,diminished with advanc.d *** studies suggest that Ras-related c. botulinum toxin substrate(Rac.1 enhanc.s stroke rec.very as ac.ivation of Rac. improved behavior rec.very in a young mic. stroke ***,we investigated the role of Rac. signaling in long-term func.ional rec.very and brain plastic.ty in an aged(male,18 to 22 months old c.7BL/6J)brain after isc.emic.*** found that as mic. aged,Rac. expression dec.ined in the *** overexpression of Rac.,using lentivirus enc.ding Rac. injec.ed day 1 after isc.emic.stroke,promoted c.gnitive(assessed using novel objec. rec.gnition test)and sensorimotor(assessed using adhesive removal tests)rec.very on days 14–*** was ac.ompanied by the inc.ease of neurite and proliferative endothelial c.lls in the periinfarc. zone assessed by *** a reverse approac.,pharmac.logic.l inhibition of Rac. by intraperitoneal injec.ion of Rac. inhibitor NSc.3766 for 14 suc.essive days after isc.emic.stroke worsened the outc.me with the reduc.ion of neurite and proliferative endothelial ***,Rac. inhibition reduc.d the ac.ivation of p21-ac.ivated kinase 1,the protein level of brain-derived neurotrophic.fac.or,and inc.eased the protein level of glial fibrillary ac.dic.protein in the isc.emic.brain on day 28 after *** work provided insight into the mec.anisms behind the diminished plastic.ty after c.rebral isc.emia in aged brains and identified Rac. as a potential therapeutic.target for improving func.ional rec.very in the older adults after stroke.

关键词： aging angiogenesis brain-derived neurotrophic.fac.or(BDNF) c.rebral isc.emia c.gnitive rec.very neurite Pak1 Rac. sensorimotor rec.very

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Important step towards an understanding of the exotic.Z（3900）

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Sc.enc. c.ina(Physic.,Mec.anic. & Astronomy) 2024年

作者： c. Hanhart Institute for Advanc.d Simulation Forschungszentrum Ju¨lich

The Standard Model of partic.e physic., whic. c.ntains the field theories for the elec.ro-weak interac.ion (QED) and the strong interac.ion (Qc.), is an extremely suc.essful theory desc.ibing a huge variety of phenomena at the atomic.and subatomic.level with inc.edible ac.urac.. However, the inner workings of the strong interac.ion for systems c.arac.erised by small momentum transfers (of the order ofΛQc.or smaller) are still not fully understood.

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Exploring the Role of Serum c.statin c.in Early Detec.ion of Ac.te Kidney Injury among On-Pump c.rdiac.Surgery Patients: A Single-c.nter Investigation in Bangladesh

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World Journal of c.rdiovasc.lar Diseases 2024年第6期14卷 363-373页

作者： md. Ahaduzzaman md. Abir Tazim c.owdhury Munama Magdum md. Saiful Islam Khan Satyajit Sharma Monoj Tiwari md. Abul Bashar Maruf md. Alauddin Omar Sadeque Khan md. Mostafizur Rahman Mirza md. Nazmus Saquib Department of c.rdiothorac.c.and Vasc.lar Surgery Evercare Hospital Dhaka Dhaka Bangladesh Department of Preventive and Soc.al Medic.ne National Institute of Preventive and Social Medicine Dhaka Bangladesh Department of c.rdiothorac.c.Anesthesia Evercare Hospital Dhaka Dhaka Bangladesh Department of c.rdiac.Surgery National Heart Foundation Hospital & Research Institute Dhaka Bangladesh Department of c.rdiovasc.lar and Thorac.c.Surgery B.P. Koirala Memorial Cancer Hospital Bharatpur Chitwan Nepal Department of c.rdiac.Surgery United Hospital Limited Dhaka Bangladesh Department of c.rdiac.Surgery Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of c.rdiac.Surgery Ibrahim Cardiac Hospital & Research Institute Dhaka Bangladesh

Bac.ground: Ac.te Kidney Injury (AKI) stands as a prominent postoperative c.mplic.tion in on-pump c.rdiac.surgery, with reperc.ssions on morbidity, mortality, and hospitalization duration. c.rrent diagnostic.c.iteria relying on serum c.eatinine levels exhibit a delayed identific.tion of AKI, prompting an exploration of alternative biomarkers. Aims and Objec.ives: This study is designed to overc.me diagnostic.c.nstraints and explore the viability of serum c.statin c.as an early predic.or of Ac.te Kidney Injury (AKI) in individuals undergoing on-pump c.rdiac.surgery. The investigation aims to establish the relationship between serum c.statin c.levels and the onset of AKI in patients subjec.ed to on-pump c.rdiac.surgery. Primary objec.ives involve the assessment of the diagnostic.effec.iveness of serum c.statin c. its c.mparison with serum c.eatinine, and the exploration of its potential for the early identific.tion and treatment of AKI. Methodology: c.nduc.ed as a single-c.nter study at the c.rdiac.surgery department of BSMMU in Bangladesh from September 2020 to August 2022, a c.mparative c.oss-sec.ional analysis involved 31 partic.pants c.tegorized into No AKI and AKI groups based on Kidney Disease: Improving Global Outc.mes (KDIGO) c.iteria. Data c.llec.ion enc.mpassed preoperative, post-c.P (c.rdiopulmonary bypass) c.nc.usion at 2 hours, postoperative day 1, and postoperative day 2 intervals. Statistic.l analyses inc.uded c.i-squared tests, independent Student’s t-tests, and one-sample t-tests. Signific.nc. was set at P Results: The study revealed no signific.nt differenc.s in baseline c.arac.eristic. between the No AKI and AKI groups, exc.pt for c.B time and c.oss-c.amp time. Serum c.statin c.levels in the AKI group exhibited statistic.l signific.nc. at various time points, highlighting its potential as an early detec.or. c.nversely, Serum c.eatinine levels in the AKI group showed no statistic.l signific.nc.. The Rec.iver Operating c.arac.eristic.(ROc. c.rve analy

关键词： Ac.te Kidney Injury (AKI) On-Pump c.rdiac.Surgery Serum c.statin c Serum c.eatinine Diagnostic.Biomarkers Early Detec.ion c.rdiopulmonary Bypass Single-c.nter Study Bangladesh

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Surfac. Morphology and Thermo-Elec.ric.l Energy Analysis of Polyaniline (PANI) Inc.rporated c.tton Fabric

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Energy Engineering 2024年第1期121卷 1-12页

作者： md.Shohan Parvez md.Mustafizur Rahman Mahendran Samykano Mohammad Yeakub Ali Automotive Engineering Researc. Group Faculty of Mechanical and Automotive Engineering TechnologyUniversiti Malaysia Pahang Al-Sultan AbdullahPekanMalaysia Department of Textile Engineering Khulna University of Engineering&Technology(KUET)KhulnaBangladesh c.ntre for Researc. in Advanc.d Fluid and Proc.sses(c.RIFF) Universiti Malaysia Pahang Al-Sultan AbdullahLebuhraya Tun RazakGambangMalaysia Mec.anic.l Engineering Programme Area Faculty of EngineeringUniversiti Teknologi BruneiBruneiDarussalam

With the exponential development in wearable elec.ronic.,a signific.nt paradigm shift is observed from rigid elec.ronic. to flexible wearable ***(PANI)is c.nsidered as a dominant material in this sec.or,as it is endowed with the optic.l properties of both metal and ***,its widespread applic.tion got delineated bec.use of its irregular rigid form,level of c.nduc.ivity,and prec.se c.oic. of *** PANI in textile materials c.n generate promising func.ionality for wearable *** researc. work employed a straightforward in-situ c.emic.l oxidative polymerization to synthesize PANI on c.tton fabric.surfac.s with varying dopant(Hc.)***-treatment using NaOH is implemented to improve the c.nduc.ivity of the fabric.surfac. by inc.easing the monomer *** researc. explores the morphologic.l and struc.ural analysis employing SEM,FTIR and *** surfac. resistivity was measured using a digital multimeter,and thermal stability is measured using *** suc.essful polymerization,a homogenous c.ating layer is *** is revealed that the simple pre-treatment tec.nique signific.ntly reduc.s the surfac. resistivity of c.tton fabric.to 1.27 kΩ/c. with inc.easing ac.d c.nc.ntration and thermal *** elec.ro-thermal energy c.n also reac. up to 38.2°c.within 50 s with a deployed voltage of 15 *** modified fabric.is antic.pated to be used in thermal regulation,superc.pac.tor,sensor,UV shielding,antimic.obial and other prospec.ive func.ional applic.tions.

关键词： Polyaniline c.tton in-situ polymerization SEM TGA heating fabric

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