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Advanced Nanocomposite Arabic Gum Polyacrylic Acid Hydrogels for Flexible Supercapacitors

Journal of Renewable Materials 2024年第7期12卷 1219-1236页

作者： Borhan Albiss asala saleh Nanotechnology Institute Jordan University of Science and TechnologyP.O.Box 3030Irbid22110Jordan

In this work,the fabrication and characterization of the nanocomposite hydrogel,as a solid electrode in electro-chemical cell and gel electrolyte material using Indium titanium oxide/polyethylene terephthalate(ITO/PET)ﬂex-ible substrate for double-layer supercapacitors have been *** nanocomposite hydrogel composed of Arabic gum(AG),Acrylic acid(AA),reduced graphene oxide(RGO),and silver nanoparticles(AgNPs)was fab-ricated via a physical cross-linked polymerization reaction,in which the ascorbic acid was used as a reducing agent to generate AgNPs and to convert Graphene oxide(GO)to RGO during the polymerization *** morphology and structural characteristics of nanocomposite hydrogel were investigated using atomic force microscopy(AFM),scanning electron microscope(SEM),Fourier transfer infrared(FTIR),and X-rayﬂuores-cence(XRF).Additionally,the effect of RGO and AgNPs on hydrogel stability was assessed through Thermogra-vimetric analysis(TGA)and differential scanning calorimetry(DSC),while its mechanical properties were studied using the nanoindentation *** impedance spectroscopy(EIS),and cyclic voltammetry(CV)were also conducted to study the electrochemical properties of the prepared *** effects of AgNPs,RGO,and water content were all considered in the study of supercapacitor *** microstructural tests showed that the nanocomposite hydrogel has a relatively high swelling rate,which has a crucial effect on the ***,the effects of increasing AgNP concentration and water content in the hydrogel matrix showed a signiﬁcant improvement in its electrochemical performance,compared with that for Arabic gum poly acrylic acid(AGPAA)hydrogel itself,were the speciﬁc capacitance exhibited a signiﬁcant enhancement,convert-ing from a low value to a substantially higher capacitance ***,when the nanocomposite hydrogel was used as the working electrode in an electrochemical cell with a hydrochloric acid

关键词： Supercapacitor energy harvesting nanocomposite hydrogel reduced graphene oxide

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Aqueous Leaves Extract of Gongronema latifolium (Benth) Downregulates the Expression of IFN-γ, IL-10 and Cell Surface Markers in Rabbits

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Open Journal of Medical Microbiology 2022年第4期12卷 117-128页

作者： Adekunle Babajide Rowaiye Moses Njoku Angus Nnamdi Oli Nwamaka Henrietta Igbokwe Titilayo asala Suliat Adebola Salami Ikemefuna Chijioke Uzochukwu Charles Okechukwu Esimone Department of Medical Biotechnology National Biotechnology Development Agency Abuja Nigeria Department of Pharmaceutical Microbiology and Biotechnology Faculty of Pharmaceutical Sciences Nnamdi Azikiwe University Agulu Nigeria Department of Pharmaceutical Microbiology and Biotechnology Faculty of Pharmaceutical Sciences Nnamdi Azikiwe University Agulu Nigeria Department of Pharmaceutical Microbiology and Biotechnology Nigerian Institute of Pharmaceutical Research & Development Abuja Nigeria Department of Pharmaceutical Microbiology and Biotechnology Faculty of Pharmacy College of Medicine Campus University of Lagos Akoka Nigeria Bio-Entrepreneurship and Extension Services Department National Biotechnology Development Agency Abuja Nigeria Department of Pharmaceutical and Medicinal Chemistry Faculty of Pharmaceutical Sciences Nnamdi Azikiwe University Agulu Nigeria

Background: The pathophysiology of the inflammatory process reveals intricate signaling which includes the IL-1β, IL-6, and TNFα pathways that could serve as drug targets. Aim: This study determined the effect of the aqueous extract of Gongronema latifolium (AEGL) leaves on the expression of IFNγ, IL-10, CD3, and CD56 in rabbits. Materials and Methods: ELISA tests were performed to determine the effect of the AEGL on the expression of a pro-inflammatory cytokine (IFNγ), an anti-inflammatory cytokine (IL-10), and CD3 and CD56 cell surface markers in rabbits. Twenty cross-bred male rabbits with an average weight range of 1.0 - 1.5 kg were selected. The rabbits were separated into four groups of four rabbits each treated as follows: Grp1 is the untreated control;Grp2 is the treated control;and Grp3, Grp4, and Grp5 were treated with 200, 400, and 600 mg/kg of AEGL respectively for 28 days. Results: The AEGL showed its greatest inhibitory effect in Group 4 on IL-10 (118.5 pg/ml), and IFNγ (332 pg/ml) on days 14 and 21 respectively. AEGL also showed the highest inhibition of CD3 expression on days 14 and 21 (0 pg/ml) in Group 3;and CD56 expression on day 21 (630.5 pg/ml) in Group 4. Conclusion: AEGL showed exhibited strong T cell mediated anti- inflammatory, and immunomodulatory activity in test rabbits within the 28-day period which can be confirmed by cell based assays. Specifically at 400 mg/kg, AEGL exhibited the greatest anti-inflammatory activity which is suggestive of its maximum effective dose.

关键词： Inflammation Cell Surface Markers Antioxidant Activity Cytokine Hepatic Toxicity Medicinal Plant Gongronema latifolium

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Nigerian Population Research on Environment,Gene and Health (NIPREGH)-objectives and protocol

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The Journal of Biomedical Research 2014年第5期28卷 360-367页

作者： Augustine N Odili John O Ogedengbe Maxwell Nwegbu Felicia O Anumah Samuel asala Jan A Staessen Department of Internal Medicine Faculty of Clinical SciencesCollege of Health SciencesUniversity of Abuja Studies Coordinating Centre Division of Hypertension and Cardiovascular RehabilitationDepartment of Cardiovascular DiseasesUniversity of Leuven Department of Human Physiology Faculty of Basic Medical ScienceChemical PathologyFaculty of Basic ClinicalAnatomical SciencesFaculty of Basic Medical SciencesCollege of Health SciencesUniversity of Abuja Department of Epidemiology University of MaastrichtMaastrichtThe Netherlands

Sub-Saharan Africa is currently undergoing an epidemiological transition from a disease burden largely attributable to communicable diseases to that resulting from a combination of both communicable and chronic non-communicable *** on chronic disease incidence,lifestyle,environmental and genetic risk factors are sparse in this *** report aimed at providing relevant information in respect to risk factors that increase blood pressure and lead to development of intermediate cardiovascular *** presented the rationale,objectives and key methodological features of the Nigerian Population Research on Environment,Gene and Health（NIPREGH） *** challenges encountered in carrying out population study in this part of the world and the approaches at surmounting them were also *** preliminary data as at 20 November 2013 showed that out of the 205 individuals invited starting from early April 2013,160（72 women） consented and were enrolled;giving a response rate of 78%.Participants＇ age ranged from 18 to 80 years,with a mean（SD） of 39.8（12.4） years and they were of 34 different ethnic groups spread over 24 states out of the 36 states that constitute *** mean（SD） of office and home blood pressures were 113.0（15.2） mm Hg systolic,73.5（12.5） mm Hg diastolic and 117.3（15.0） mm Hg systolic,and 76.0（9.6） mm Hg diastolic,***-three（26.8%） participants were hypertensive and 8（5.0%） were *** addition to having the unique potential of recruiting a cohort that is a true representative of the entire Nigerian population,NIPREGH is feasible and the objectives realisable.

关键词： Africa black populations blood pressure hypertension population science

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