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对INTERHEART数据的进一步分析:研究结果的启示

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世界核心医学期刊文摘（心脏病学分册） 2006年第3期2卷 15-17页

作者： arya Sharma

心血管疾病(CVD)对社会造成的沉重负担是当今人类面临的巨大挑战.人们对CVD的认识时间已相当长了,世界范围内医疗界已积累了许多有关这方面的知识,但是关于该疾病,我们不了解的方面还有很多.例如,一般认为北美与其他地方的CVD在某些方... 详细信息

心血管疾病(CVD)对社会造成的沉重负担是当今人类面临的巨大挑战.人们对CVD的认识时间已相当长了,世界范围内医疗界已积累了许多有关这方面的知识,但是关于该疾病,我们不了解的方面还有很多.例如,一般认为北美与其他地方的CVD在某些方面有所不同,如日本或埃及.另外CVD很复杂,其病因和结果的因素仅一半左右为我们所知.换句话说,可能还有很多其他的致病因素(如上皮的组成、黏附分子等)有待我们认识.这些假设无疑得到了临床研究得出的CVD相关危险因素的证实,还不很清楚这些结果是否能应用到其他人群中.

关键词：心血管疾病相关危险因素致病因素世界范围内 CVD 黏附分子临床研究医疗界

Post-adoption behaviour of farmers towards soil and water conservation technologies of watershed management in India

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International Soil and Water Conservation Research 2015年第3期3卷 161-169页

作者： Gopal Lal Bagdi Prasanta Kumar Mishra Ravi Sankar Kurothe Swarn Lata arya Shekhargouda Linganagouda Patil Ashok Kumar Singh Bankey Bihari Om Prakash Ashok Kumar Palanisamy Sundarambal ICAR–Central Sheep and Wool Research Institute Avikanagar 304501RajasthanIndia ICAR–Indian Institute of Soil and Water Conservation Dehradun 248195UttrakhandIndia

The Indian Institute of Soil and Water Conservation(IISWC)and its Research Centres have developed many successful model watershed projects in India in the past and implemented many Soil and Water Conservation(SWC)technologies for sustainable watershed *** many evaluation studies were conducted on these projects in the past,there has been no assessment of the post-adoption status of the SWC technologies over a longer *** was imperative to appraise the behaviour of the farmers with regard to the continuance or discontinuance of the technologies adopted,diffusion or infusion that took place and technological gaps that occurred in due course of time in the post watershed ***,it was realized that the postadoption behaviour of beneficiary farmers who have adopted different soil and water conservation technologies for watershed management projects should be studied in *** research study was initiated in 2012 as a core project at Vasad as the lead Centre along with IISWC headquarter Dehradun,and Centres Agra,Bellary,Chandigarh,Datia,Kota&Ooty,with the specific objectives of the study to measure the extent of post-adoption behaviour(continued-adoption,discontinuance,technological gap,diffusion and infusion)of farmers towards the adopted SWC technologies of watershed *** the present study various indices regarding continued adoption,dis-adoption(discontinuance),technological gap,diffusion,infusion regarding soil and water conservation technologies for watershed management were developed for measurement of post-adoption behaviour of *** was revealed that a little less than three-fourth(73%)of SWC technologies continued to be adopted and more than onefourth(27%)were discontinued by *** of the total continue adopted SWC technologies by farmers,a little less than onefifth(19%)of technologies continued to be adopted with a technological *** than one-fourth(28%)of SWC technologies were also diffused to other fa

关键词： Post-adoption Soil and water conservation Watershed Management

Prevalence and Sex Distribution of Temporomandibular Disorder and Their Association with Anxiety and Depression in Indian Medical University Students

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International Journal of Clinical Medicine 2015年第8期6卷 570-578页

作者： Kaberi Majumder Shalender Sharma Dayashankara Rao JK Vijay Siwach Varun arya Sunil Gulia Department of Orthodontics SGT Dental College Gurgaon India Department of Oral and Maxillofacial Surgery SGT Dental College Gurgaon India

Objectives: The term TMD refers to a group of disorders characterized by pain in the temporomandibular joint and associated structures. The aim of this study was designed to evaluate prevalence, severity and sex distribution of sign and symptoms of TMD and to evaluate their relation with anxiety and depression among the students. Material and Methods: A total of 1000 university students were enrolled in the study (550 females;450 males), with ages ranged between 18 and 28 years. Helkimo anamnestic index (Ai) and clinical dysfunction index (Di) were used to determine symptoms and signs respectively. For the association of TMD with anxiety and depression, HAD (Hospital Anxiety and Depression) scale was used. Results showed that prevalence of one or more symptoms of TMD was 27.7%, while the prevalence of one or more signs of TMD was 64.4% which was mild in severity. Mild anamnestic symptoms (AiI) were found in 19.8% and severe symptoms (AiII) were found in 7.6%, while mild clinical sign (DiI), moderate clinical (DiII) and severe clinical sign (DiIII) were found in 49.7%, 12.2% and 2.4% respectively. Statistically there was no gender difference in these two scales. Regarding the association between TMD with anxiety and depression, 206 of the 311 students (66.2%) with TMD symptoms also had signs of anxiety and depression (P < 0.001). Conclusion: These findings confirmed that students had high prevalence of TMD which was significantly associated with anxiety and depression.

关键词： TMD Helkimo Index HAD Scale Anxiety

Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography

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Eye and Vision 2020年第4期7卷 275-283页

作者： Osama A.Sorour Nihaal Mehta Caroline R.Baumal Akihiro Ishibazawa Keke Liu Eleni K.Konstantinou Sarah Martin Phillip Braun A.Yasin Alibhai Malvika arya Andre J.Witkin Jay S.Duker Nadia K.Waheed Department of Ophthalmology New England Eye CenterTufts Medical Center800 Washington StreetBox 450BostonMA 02111USA Department of Ophthalmology Tanta UniversityTantaEgypt The Warren Alpert Medical School of Brown University ProvidenceRhode IslandUSA Department of Ophthalmology Asahikawa Medical UniversityHokkaidoJapan University of Hawai’i John A.Burns School of Medicine HonoluluHIUSA Yale School of Medicine New HavenConnecticutUSA

Background:To examine the baseline morphological characteristics and alterations in intraretinal microvascular abnormalities(IRMAs)in response to anti-vascular endothelial growth factor(anti-VEGF)treatment,documented by optical coherence tomography angiography(OCTA)in diabetic ***:In this retrospective study,IRMAs were evaluated with multimodal imaging(fundus photography,fluorescein angiography,OCTA)in treatment-naïve diabetic eyes before and after anti-VEGF treatment for diabetic macular edema(DME)and/or proliferative diabetic retinopathy(PDR)and compared to diabetic control eyes with similar diabetic retinopathy(DR)severity that did not receive anti-VEGF *** morphological characteristics of IRMAs on enface OCTA imaging were graded by masked readers at baseline,then after anti-VEGF therapy in treated eyes or after observation in control *** of interval changes in an IRMA were based on the following parameters:branching,vessel caliber and area of adjacent capillary ***:The treated group included 45 IRMA foci from 15 eyes of 11 patients,while the control group included 27 IRMA foci from 15 eyes of 14 *** anti-VEGF treatment,enface OCTA demonstrated that 14 foci of IRMA(31%)demonstrated regression with normalization of appearance of the capillary bed,20 IRMAs(44%)remained unchanged,six IRMAs(13%)progressed with enlargement or development of new IRMAs and five IRMAs(11%)demonstrated complete obliteration defined as IRMA disappearance with advancing capillary *** the control group,17 IRMA(63%)remained stable,8 IRMAs(29.6%)progressed and 2 experienced total obliteration(7.4%).The difference in rank order between the two groups was statistically significant(p=0.022).Conclusions:In eyes with DR status post anti-VEGF therapy,foci of IRMAs have a variable course demonstrating one of four possible outcomes:regression,stabilit,progression or complete *** contrast,none of the untreated contr

关键词： Retina Ischemia Anti-VEGF DME PDR OCTA

Introducing an Innovative Method to Treat Spastic Cerebral Palsy with Faster Recovery Time: Post-Achilles Tendon Lengthening with Bandaging

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Journal of Biosciences and Medicines 2021年第12期9卷 30-39页

作者： Hamed Yazdanshenas Firoozeh Madadi Kevin Perez Eleby Rudolph Washington III arya Nick Shamie Firooz Madadi Department of Orthopedic Surgery College of Medicine Charles R. Drew University of Medicine and Science (CDU) Los Angeles USA Department of Orthopedic Surgery David Geffen School of Medicine University of California Los Angeles (UCLA) Los Angeles USA Department of General Surgery College of Medicine Charles R. Drew University of Medicine and Science Los Angeles (CDU) Los Angeles USA Department of Family Medicine David Geffen School of Medicine University of California Los Angeles (UCLA) Los Angeles USA Department of Family Medicine College of Medicine Charles R. Drew University of Medicine and Science Los Angeles (CDU) Los Angeles USA Department of Anesthesiology Anesthesiology Research Center Shabid Beheshti University of Medical Sciences (SBMU) Tehran Iran College of Medicine Charles R. Drew University of Medicine and Science (CDU) Los Angeles USA David Geffen School of Medicine University of California Los Angeles (UCLA) Los Angeles USA Department of Orthopedic Surgery Akhtar Hospital Shabid Beheshti University of Medical Sciences (SBMU) Tehran Iran

Equinus deformity is one of the most common musculoskeletal deformities of Cerebral Palsy (CP) which is defined as an abnormality in ankle dorsiflexion that can cause severe walking disability. The standard surgical intervention for Equinus deformity is Achilles Tendon Lengthening (ATL) with post-operative leg casting, however in some cases, it requires months of recovery post-operation to regain movement. The objective of this study was to find an alternative to leg casting that would provide a safe and faster time course to recovery. Therefore, we conducted a semi-experimental clinical trial study of a population that included 62 CP patients between the ages of 6 - 15 years of age with diplegia, hemiplegia, or quadriplegia that randomly underwent ATL followed by subsequent leg casting (control, 32 patients) or bandage and ankle-foot orthosis (AFO;experimental, 30 patients). Patients were periodically evaluated for mobility and walking ability pre-operation and at 2 weeks post- operation, 6 weeks post-operation, and then every month for 6 months. We found that all 32 patients in the experimental group regained their walking ability within two weeks (100%), while majority of patients in the control group (84%) regained their walking ability after 4 - 6 weeks, regardless of CP type. We also found that on 6-month follow-up, progression of walking abilities was similar in both groups. Rupture of the repaired tendon was not observed in any of the participants in either group. This study suggests applying a bandage with a foot or ankle orthosis as an alternative to long leg cast in children of 15 years of age or younger with CP treated with ATL for Equinus deformity to facilitate faster post-operative recovery. It also recommends follow-up studies on confounding factors, categorization of pre- and post-operative range of movement, and post-op complications with longer follow up while treating CP patient with ATL followed by AFO.

关键词： Cerebral Palsy Equinus Deformity Recovery

Microscopic and metabolic investigations disclose the factors that lead to skin cracking in chili-type pepper fruit varieties

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Horticulture Research 2023年第4期10卷 211-224页

作者： Ofir Marinov Gal Nomberg Sutanni Sarkar Gulab Chand arya Eldad Karavani Einat Zelinger Ekaterina Manasherova Hagai Cohen Department of Vegetable and Field Crops Institute of Plant SciencesAgricultural Research Organization(ARO)Volcani InstituteRishon LeZion 7505101Israel Department of Plant Pathology and Microbiology The Robert H.Smith Faculty of AgricultureFood and EnvironmentThe Hebrew University of JerusalemRehovot 7610001Israel Center for Scientific Imaging(CSI) The Robert H.Smith Faculty of AgricultureFood and EnvironmentThe Hebrew University of JerusalemRehovot 7610001Israel

The hydrophobic cuticle encasing the fruit skin surface plays critical roles during fruit development and *** failure often results in the fruit surface cracking and forming a wound-periderm tissue made of suberin and *** factors that make the fruit skin susceptible to cracking have yet to be fully ***,we investigated two varieties of chili peppers(Capsicum annuum L.),Numex Garnet,whose fruit has intact skin,and Vezena Slatka,whose fruit has cracked *** observations,gas chromatography-mass spectrometry,biochemical and gene expression assays revealed that Vezena Slatka fruit form a thicker cuticle with greater levels of cutin monomers and hydroxycinnamic acids,and highly express key cutin-related *** skin of these fruit also had a lower epidermal cell density due to cells with very large perimeters,and highly express genes involved in epidermal cell *** demonstrate that skin cracking in the Vezena Slatka fruit is accompanied by a spatial accumulation of lignin-like polyphenolic compounds,without the formation of a typical wound-periderm tissues made of suberized ***,we establish that skin cracking in chili-type pepper significantly affects fruit quality during post-harvest storage in a temperature-dependent *** conclusion,our data highlight cuticle thickness and epidermal cell density as two critical factors determining fruit skin susceptibility to cracking in chili-type pepper fruit.

关键词： varieties pepper cracking

Efficacy of Haemocoagulase as a Topical Haemostatic Agent after Minor Oral Surgical Procedures—A Prospective Study

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International Journal of Clinical Medicine 2014年第14期5卷 875-883页

作者： Kaberi Majumder Shalender J. K. Dayashankara Rao Neelima Gehlot Varun arya Vijay Siwach Department of Oral and Maxillofacial Surgery SGT Dental College Gurgaon India Department of Orthodontics SGT Dental College Gurgaon India

Purpose: Haemocoagulase is a topical haemostatic agent which provides the adequate haemostasis after minor oral surgical procedures and it has also been proved to be beneficial in promoting wound healing. The aim of this study was to check the efficacy of haemocoagulase in stopping the bleeding and its effect over wound healing after the minor oral surgical procedure. Material & Method: This study is comprised of 150 surgical sites in 75 patients. The subjects were divided into 2 groups in which Group 1 consists of 50 surgical sites in 25 patients and Group II consists of 100 surgical sites in 50 patients. Group I comprised of the group of simple extraction. In these patients one tooth socket was selected as haemocoagulase site and the other socket was the control group in which no drug was used to control haemorrhage. Group II comprised of the group of patients with bilateral impactions. 50 sockets and surgical sites were sprinkled with Haemocoagulase, and 50 sockets and surgical sites were used as control side in which no drug was used to control haemorrhage. Results: In Group I bleeding was stopped with the average time of 1.35 minutes, while at control side bleeding was stopped with the average time of 2.25 minutes. In Group II bleeding was stopped with average time for haemostasis being 1.46 minutes, while at control side the bleeding was stopped in an average time of 2.43 minutes. Conclusion: Haemocoagulase after minor oral surgery not only provides faster haemostasis but also enhances healing.

关键词： Local Haemostatic Agents Haemocoagulase Botox

Fractal Interpolation Functions: A Short Survey

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Applied Mathematics 2014年第12期5卷 1834-1841页

作者： María Antonia Navascués arya Kumar Bedabrata Chand Viswanathan Puthan Veedu María Victoria Sebastián Centro Universitario de la Defensa de Zaragoza Academia General Militar Zaragoza Spain Departamento de Matemática Aplicada EINA Universidad de Zaragoza Zaragoza Spain Department of Mathematics Indian Institute of Technology Madras Chennai India

The object of this short survey is to revive interest in the technique of fractal interpolation. In order to attract the attention of numerical analysts, or rather scientific community of researchers applying various approximation techniques, the article is interspersed with comparison of fractal interpolation functions and diverse conventional interpolation schemes. There are multitudes of interpolation methods using several families of functions: polynomial, exponential, rational, trigonometric and splines to name a few. But it should be noted that all these conventional nonrecursive methods produce interpolants that are differentiable a number of times except possibly at a finite set of points. One of the goals of the paper is the definition of interpolants which are not smooth, and likely they are nowhere differentiable. They are defined by means of an appropriate iterated function system. Their appearance fills the gap of non-smooth methods in the field of approximation. Another interesting topic is that, if one chooses the elements of the iterated function system suitably, the resulting fractal curve may be close to classical mathematical functions like polynomials, exponentials, etc. The authors review many results obtained in this field so far, although the article does not claim any completeness. Theory as well as applications concerning this new topic published in the last decade are discussed. The one dimensional case is only considered.

关键词： Fractal Curves Fractal Functions Interpolation Approximation

Comparative study of multiple cancellous screws versus sliding hip screws in femoral neck fractures of young adults

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Chinese Journal of Traumatology 2016年第4期19卷 209-212页

作者： Mayank Gupta Rajendra Kumar arya Satish Kumar Vijay Kumar Jain Skand Sinha Ananta Kumar Naik Department of Orthopedics Post Graduate Institute of Medical Education and Research Dr Ram Manohar Lohia Hospital New Delhi 110001 India

Purpose： Both cannulated cancellous screw （CCS） and sliding hip screw （SHS） are used in femoral neck fracture fixations, hut which is superior is yet to be determined. This study was aimed to compare the clinicoradiological outcome of femoral neck fracture treated with SHS or CCS in young adults. Methods： Adults （16-60 years） with femoral neck fracture were divided into Group I fixed with SHS and Group 2 fixed with three CCS after closed reduction. Pain relief, functional recovery and postoperative radiographs at 6 weeks, 3 months, 6 months and then yearly for upto 4 years were analyzed. Results： Group 1 （n = 40） achieved radiological union at mean of Z6 months, with the union rate of 8Z5% （n = 35）, avascular necrosis （AVN） rate of 7.5% （n - 3） and mean Harris Hip Score （HHS） of 86.15 at the end of 4 years. In Group 2 （n = 45） these parameters were union at Z1 months, union rate of 82.22% （n = 37）, AVN rate of 6.67% （n = 3） and HHS of 88.65. Comparative results were statistically insignificant. Conclusion： There is no significant difference in clinicoradiological outcome between the two implants.

关键词： Femoral neck fractures Bone screws Young adult