检索结果-南通市图书馆

Latent hepatitis B is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C

World Journal of Gastroenterology 2013年第48期19卷 9328-9333页

作者： arvind reddy Elizabeth May Murray Ehrinpreis Milton Mutchnick Division of Gastroenterology Wayne State University Detroit MI 48201 United States

AIM:To study the potential association between hepatocellular carcinoma(HCC)in patients with chronic hepatitis C(CHC),cirrhosis and latent hepatitis B(LHB)infection,defined as the absence of detectable serum hepatitis B surface antigen(HBsAg)and the presence of hepatitis B core antibody(HBcAb).METHODS:This retrospective analysis is comprised of 185 cirrhotic patients with HCC who were hepatitis C virus antibody(HCV Ab)(+)and HBsAg(-)at Wayne State University between 1999 and *** these,108 patients had HCV polymerase chain reaction confirmation of viremia while the remaining(77)were considered to have CHC on the basis of a positive HCV Ab and the absence of any other cause of liver *** were drawn from our institutional database from the same time period and consisted of 356 HBsAg(-)age,race and gender matched patients with HCV RNA-confirmed CHC and without evidence of HCC.A subgroup of controls included 118matched patients with liver cirrhosis.χ2test and t test were used for data ***:Seventy-seven percent of patients in all3 groups were African *** with HCC had a significantly higher body mass index(P=0.03),a higher rate of co-infection with human immunodeficiency virus(HIV)(P=0.05)and a higher prevalence of alcohol abuse(P=0.03)than the *** patients with HCC had LHB than controls(78%vs39%,P=0.01).Sixty three percent of patients with HCC were both hepatitis B surface antigen(HBsAb)(-)and HBcAb(+)compared to 23%of controls(P<0.01).When compared to cirrhotic controls,the frequency of HBcAb(+)remained higher in patients with HCC(78%vs 45%,P=0.02).Patients with HCC were more likely to be both HBsAb(-)and HBcAb(+)than the cirrhotic controls(63%vs 28%,P=0.01).Although not statistically significant,100%of CHC and HIV coinfected patients with HCC(n=11)were HBcAb(+)when compared to controls(44%;n=9).CONCLUSION:These data suggest that LHB occurs at a significantly increased frequency in patients with CHC and HCC than in

关键词： Hepatocellular carcinoma Chronic hepatitis C Latent hepatitis B Hepatitis C virus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Importance of etiologies of secondary diabetes:How often do we think off in clinical practice?

引用

World Journal of Clinical Cases 2025年第5期13卷 49-51页

作者： Kotha Sugunakar reddy arvind Kumar Morya Archana Gaur Sakthivadivel Varatharajan Department of General Medicine All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Physiology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

The article"Secondary diabetes due to different etiologies:Four case reports"by Song et al,published in the World Journal of Clinical Cases,delves into the identi-fication of rare causes of secondary diabetes and emphasizes the necessity for healthcare professionals to recognize these *** to do so can result in treatment delays and compromised patient *** article discusses spe-cific types of diabetes,including maturity onset of diabetes in young,pancreas-related diseases,endocrinopathies,drug-induced diabetes,infections,and con-genital genetic syndromes associated with diabetes *** summaries highlight how patients with secondary diabetes,stemming from conditions such as Williams-Beuren syndrome and pituitary adenoma,often exhibit distinct characteristics overlooked in clinical *** authors stress the importance of a holistic diagnostic approach and advocate for proactive management through early intervention,including genetic tests and antibody *** awa-reness and education are crucial for timely identification and proper management,ultimately improving patient *** findings prompt a call to action for healthcare professionals to consider rare causes of secondary diabetes,facili-tating better glycemic control and overall patient care.

关键词： Diabetes mellitus Etiologies Viral infections Syndromes Pathophysiology,Secondary diabetes mellitus,Clinical practice

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chiglitazar and Thiazolidinedione in patients with type 2 diabetes:Which is better?

引用

World Journal of Diabetes 2024年第3期15卷 565-567页

作者： Kotha Sugunakar reddy Archana Gaur Sakthivadivel Varatharajan arvind Kumar Morya Department of General Medicine All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Physiology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Medicine All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

This published Meta-Analysis by Lin et al is an indirect comparison between two drugs Chiglitazar and Thiazolidinedione which are commonly used for glycemic control in type-Ⅱ diabetes *** terms of safety and efficacy... 详细信息

关键词： Type-Ⅱdiabetes mellitus Glucose intolerance Hyperglycemia Research methodology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multitract percutaneous nephrolithotomy in staghorn calculus

引用

Asian Journal of Urology 2020年第2期7卷 94-101页

作者： arvind P.Ganpule MNaveen Kumar reddy SBSudharsan Shaishav BShah Ravindra BSabnis Mahesh RDesai Department of Urology Muljibhai Patel Urological HospitalNadiadIndia NHL Municipal Medical College AhmedabadIndia

Staghorn calculi are branched stones which occupy a majority portion of the pelvicaliceal *** untreated staghorn calculus over time can damage the kidney and deteriorate its function and/or cause life threatening *** stone clearance is an important goal in order to eradicate any infective focus,relieve obstruction,prevent recurrence and preserve the kidney *** nephrolithotomy(PCNL)is currently the accepted first-line treatment option for staghorn *** options available are single-tract PCNL with an auxiliary procedure like shockwave lithotripsy,single-tract PCNL with flexible nephroscopy,or multitract *** has its own pros and *** the ultimate goal of treatment for any patient with staghorn calculi should be safety,cost-effectiveness,and to achieve total stone *** this article,we review the management of staghorn calculi with multiple percutaneous(“multitract”)access,its advantages and disadvantages and its current position by studying the various published materials across the globe.

关键词： Percutaneous nephrolithotomy Staghorn Multitract Kidney Stone

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural product based novel small molecules with promising neurotrophic,neurogenic and anti-neuroinflammatory actions can be developed as stroke therapeutics

引用

Neural Regeneration Research 2016年第6期11卷 916-917页

作者： Priya Jhelum R.Gajendra reddy arvind Kumar Sumana Chakravarty Chemical Biology CSIR-Indian Institute of Chemical TechnologyHyderabadIndia CSIR-Centre for Cellular and Molecular Biology HyderabadIndia

Stroke is the world’s second leading cause of death and a major cause of adult *** the different kinds of stroke,ischemic stroke is the most widely prevalent type,causing high morbidity and mortality worldwide（Mosko... 详细信息

关键词： neurotrophic neurogenic disability deprivation neurological neurotrophin nutrients hippocampal mortality regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High sodium causes hypertension: evidence from clinical trials and animal experiments

引用

Journal of Integrative Medicine 2015年第1期13卷 1-8页

作者： Vamsi reddy arvind Sridhar Roberto F.Machado Jiwang Chen Section of Pulmonary Critical Care Medicine Sleep and Allergy Department of Medicine University of Illinois at Chicago

Hypertension is a cardiovascular disease affecting approximately one out of every seven people worldwide. High-sodium consumption has been generally accepted as a risk factor for developing hypertension. Today, global sodium consumption greatly exceeds guidelines recommended by all medical institutions. This review synthesizes the data of landmark mammalian and human studies which investigated the role of sodium in the pathogenesis of hypertension, along with modern studies questioning this relationship. Recent studies concerning the potential pathways by which high-sodium concentration induces hypertension were reviewed. Human trials and population studies revealed a strong correlation between high blood pressure and average dietary sodium; and animal studies found a dramatic reduction in vascular function in a variety of mammals treated with high-sodium diets. In spite of a few contrarian studies, we found overwhelming evidence that elevated sodium consumption could cause hypertension

关键词： high salt hypertension clinical trial models, animal reviews

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

COVID-19 in Liver Transplant Recipients-A Series with Successful Recovery

引用

Journal of Clinical and Translational Hepatology 2020年第4期8卷 467-473页

作者： Ashok Choudhury Golamari Srinivasa reddy Shantan Venishetty Viniyendra Pamecha Saggere Muralikrishna Shasthry arvind Tomar Lalita Gauri Mitra Venkata Siva Tez Prasad Rajendra Prasad Mathur Debajyoti Bhattacharya Shiv Kumar Sarin Department of Hepatology and Liver Transplant Institute of Liver and Biliary SciencesNew DelhiIndia Department of HPB Surgery and Liver Transplant Institute of Liver and Biliary SciencesNew DelhiIndia Department of Pulmonary Medicine Institute of Liver and Biliary SciencesNew DelhiIndia Department of Critical Care Medicine Institute of Liver and Biliary SciencesNew DelhiIndia Department of Nephrology Institute of Liver and Biliary SciencesNew DelhiIndia

The severe acute respiratory syndrome corona virus-2 (referred to as SARS-CoV-2) pandemic had a great impact on public life in general as well as on populations with pre-existing disease and co-morbidities. Liver transplant and immunosuppressant medication predisposes to more severe disease and is often associated with poor outcome. The clinical features, disease course, treatment and process of modulating the immunosuppression is challenging. Here, we describe the clinical presentation, treatment and outcomes in six liver transplant recipients. Out of those six patients, three had mild, one had moderate and one had severe COVID-19, and one was asymptomatic. The immunosup-pression minimization or withdrawal was done based upon the clinical severity. Consideration of tocilizumab and/or convalescent plasma as well as antivirals i.e. remdesvir done in severe cases. The routine practice of prophylactic anti-coagulation, consideration of repurposed drugs (i.e. teico-planin and doxycycline), and watchful monitoring of asymptomatic recipients helped to achieve an uneventful recovery.

关键词： Liver transplant COVID-19 SARS-CoV-2 Liver injury Remdesivir Convalescent plasma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multiple Sexual Partners and Vulnerability to HIV: A Study of Patterns of Sexual Behaviour in the Slum Population of India

引用

World Journal of AIDS 2014年第4期4卷 373-381页

作者： Pravin K. Jha Damodar Sahu K. Srikanth reddy Padum Narayan arvind Pandey Centre for Study of Regional Development Jawaharlal Nehru University New Delhi India National Institute of Medical Statistics New Delhi India

Globally, research indicates that monogamous married women living in slums are at heightened risk of HIV men’s risky sexual behaviour. Hence, to reduce the risk of HIV transmission, there is need to understand the number, nature and variation in transition of sexual partners of men in living in slums. This paper uses India’s National Family Health Survey-3 data to estimate the variation in the type of sexual partners among sexually active men age 15 - 54 with more than one sexual partner in last 12 months prior to the survey in eight slums?of India. Among sexually active men, 1.3 percent reported having more than one sexual partner in the last 12 months prior to the survey. Men who are more likely to have two or more partners are those who are young, especially below age 25 years, never married, educated up to 5 years, and from middle class. There is a higher increase in the probability of sex with spouse from second last to the last sexual partner in non-slum areas than slum areas. However, in case of transition from other friends/relatives and female sex workers to spousal partners, there is a major decline in probability among non-slum men than slum men. These transitions are extremely important from the perspective of curbing the spread of HIV epidemic, especially in situations where women lack control over their own sexuality and seldom use condom in marital sex. Therefore, strategies focused in slums should either consider reducing men’s risky sexual behaviour or build capacities of women to negotiate safe sex in marital relationships or consider a combination of both.

关键词： Slum Sexual Partners Transition Probability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Are Truckers Being over Stigmatized as HIV Carriers in India? Evidences from Behavioral and Biological Cross-Sectional Surveys among Clients of Female Sex Workers

引用

Open Journal of Preventive Medicine 2015年第3期5卷 85-91页

作者： Damodar Sahu Sowmya Ramesh Ram Manohar Mishra K. Srikanth reddy Reena Bharadwaj Niranjan Saggurti arvind Pandey Mandar Mainkar Bitra George National Institute of Medical Statistics ICMR New Delhi India Population Council New Delhi India National AIDS Research Institute Pune India FAMILY Health International New Delhi India

This paper examines whether truckers have been over-stigmatized as HIV carriers in the country. Data were taken from cross-sectional surveys of clients of female sex workers conducted in 2006-2007 in 12 districts of the country. A total 4822 clients of female sex workers were covered in the survey. Low-income skilled/semi-skilled men, including non-agricultural/casual labor, and petty businessmen/small shop owners, have the largest share in the clients’ population. There was no significant difference between truckers and other sub-group of clients’ population in terms of consistent condom use with female sex workers and prevalence of HIV or STI. These evidences suggest that the contribution of truckers in HIV epidemic in India might to similar to other sub-groups of clients’ population. Thus, truckers might have been over-stigmatized as HIV carriers in the country. However, there is no doubt that truckers constitute an extremely important target group for the HIV prevention programs and these efforts must be continued to prevent new HIV infections in the country.

关键词： Clients Truckers Sex Workers India

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：