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Relationship between age and subfoveal choroidal thickness and its clinical implications

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World Journal of Diabetes 2024年第11期15卷 2251-2254页

作者： Sony Sinha Prateek Nishant arvind k morya Arshi Singh Department of Ophthalmology-Vitreo-Retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatna 801507BiharIndia Department of Ophthalmology ESIC Medical CollegePatna 801103BiharIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology Guru Nanak Eye CentreNew Delhi 110001New DelhiIndia

The retrospective study by Lei et al is an investigation of the relationship between age and subfoveal choroidal thickness(SFCT)in Chinese patients with proliferative diabetic *** of the study design prevent the generalizability of the study findings,limiting their clinical *** recommend consideration of stricter eligibility criteria,other variables like duration of diabetes,interpretation of gender-differences in SFCT,longitudinal follow-up,use of newer choroidal flow indices,comparison of values with normal controls,subgroup analysis to determine the effect of prior treatment,as well as consideration of various real-world scenarios in future studies.

关键词： Diabetic retinopathy Optical coherence tomography Phenotypic sex Research design Visual acuity

Intravitreal therapy for the management of diabetic retinopathy:A concise review

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World Journal of Experimental Medicine 2024年第4期14卷 104-119页

作者： Atul Arora arvind k morya Parul C Gupta Nitin k Menia Prateek Nishant Vishali Gupta Teleophthalmology Postgraduate Institute of Medical Education and ResearchChandigarh 160012PunjabIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology Post Graduate Institute of Medical Education&ResearchChandigarh 160012PunjabIndia Department of Ophthalmology All India Institute of Medical SciencesVijaypur 180001Jammu and KashmīrIndia Department of Ophthalmology ESIC Medical CollegePatna 801103BihārIndia

Diabetic retinopathy(DR)is a serious microvascular complication of diabetes mellitus and may result in irreversible visual *** treatment has been the gold standard treatment for diabetic macular edema and proliferative diabetic retinopathy for many *** late,intravitreal therapy has emerged as a cornerstone in the management of *** the diverse pharmacotherapeutic options,anti-vascular endothelial growth factor agents have demonstrated remarkable efficacy by attenuating neovascularization and reducing macular edema,thus preserving visual acuity in DR patients.

关键词： Diabetic retinopathy Intravitreal therapy Anti-vascular endothelial growth factor Macular edema Proliferative diabetic-retinopathy

Importance of etiologies of secondary diabetes:How often do we think off in clinical practice?

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World Journal of Clinical Cases 2025年第5期13卷 49-51页

作者： kotha Sugunakar Reddy arvind kumar morya Archana Gaur Sakthivadivel Varatharajan Department of General Medicine All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Physiology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

The article"Secondary diabetes due to different etiologies:Four case reports"by Song et al,published in the World Journal of Clinical Cases,delves into the identi-fication of rare causes of secondary diabetes and emphasizes the necessity for healthcare professionals to recognize these *** to do so can result in treatment delays and compromised patient *** article discusses spe-cific types of diabetes,including maturity onset of diabetes in young,pancreas-related diseases,endocrinopathies,drug-induced diabetes,infections,and con-genital genetic syndromes associated with diabetes *** summaries highlight how patients with secondary diabetes,stemming from conditions such as Williams-Beuren syndrome and pituitary adenoma,often exhibit distinct characteristics overlooked in clinical *** authors stress the importance of a holistic diagnostic approach and advocate for proactive management through early intervention,including genetic tests and antibody *** awa-reness and education are crucial for timely identification and proper management,ultimately improving patient *** findings prompt a call to action for healthcare professionals to consider rare causes of secondary diabetes,facili-tating better glycemic control and overall patient care.

关键词： Diabetes mellitus Etiologies Viral infections Syndromes Pathophysiology,Secondary diabetes mellitus,Clinical practice

Telemedicine and public health–pearls and pitfalls

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World Journal of Methodology 2025年第2期15卷 177-179页

作者： Ranjeet kumar Sinha Sony Sinha Prateek Nishant arvind kumar morya Arshi Singh Department of Community Medicine Patna Medical CollegePatna 800004BiharIndia Department of Ophthalmology-Vitreo-Retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatna 801507BiharIndia Department of Ophthalmology ESIC Medical CollegePatna 801103BiharIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology Guru Nanak Eye CenterNew Delhi 110001India

We hereby comment on the interesting systematic review by Grewal et al where they have provided an overall picture of the current status of available tele-health programs in the United States with emphasis on the Amazon *** analysis is an appreciable effort in discovering the features available and features lacking in these tele-health *** concept of tele-health originated to curtail the need for physical attendance of patients at health clinics,and has been beneficial during the coronavirus disease 2019 *** implore that the pearls and pitfalls of these programs have to be understood by policymakers prior to forming a consensus regarding the availability,accessibility and affordability of these programs as methods of healthcare *** proliferation of tele-health programs in their current form may pose threats to patient and provider safety and medicolegal ***,patients and providers must work together to improve them to meet their expectations and enable them to provide the best care for the ailing public.

关键词： Telemedicine Remote Access Availability Accessibility Affordability Ethics Privacy Medicolegal liability

Intricacies during pregnancy with gestational diabetes mellitus

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World Journal of Clinical Cases 2025年第1期13卷 62-64页

作者： Richa Rattan Rimesh Pal Parul Chawla Gupta arvind kumar morya Ripunjay Prasad Department of Endocrinology Post Graduate Institute of Medical Education and ResearchChandigarh 160012India Department of Ophthalmology Post Graduate Institute of Medical Education and ResearchChandigarh 160012PunjabIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology RP Eye InstituteDelhi 110001India

The study by Cao et al aimed to identify early second-trimester biomarkers that could predict gestational diabetes mellitus(GDM)development using advanced proteomic techniques,such as Isobaric tags for relative and absolute quantitation isobaric tags for relative and absolute quantitation and liquid chromatography-mass spectrometry liquid chromatography-mass *** analysis revealed 47 differentially expressed proteins in the GDM group,with retinol-binding protein 4 and angiopoietin-like 8 showing significantly elevated serum levels compared to *** these findings are promising,the study is limited by its small sample size(n=4 per group)and lacks essential details on the reproducibility and reliability of the protein quantification methods ***,the absence of experimental validation weakens the interpretation of the protein-protein interaction network identified through bioinformatics *** study's focus on second-trimester biomarkers raises concerns about whether this is a sufficiently early period to implement preventive interventions for *** GDM risk during the first trimester or pre-conceptional period may offer more clinical *** its limitations,the study presents valuable insights into potential GDM biomarkers,but larger,well-validated studies are needed to establish their predictive utility and generalizability.

关键词： Gestational diabetes mellitus Biomarkers Differentially expressed proteins Retinol-binding protein 4 Angiopoietin-like 8 Proteomics Lifestyle interventions Early prediction

Diabetes is affecting everyone everywhere

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World Journal of Diabetes 2024年第2期15卷 305-307页

作者： Parul Chawla Gupta Mona Duggal arvind kumar morya Department of Ophthalmology Post Graduate Institute of Medical Education&ResearchChandigarh 160012PunjabIndia School of Public Health Post Graduate Institute of Medical Education and ResearchChandigarh 160002PunjabIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

The article titled“Accessibility and Utilization of Healthcare Services Among Diabetic Patients:Is Diabetes a Poor Man’s Ailment?”gave insights into a pandemic systemic disease known as diabetes *** modern-era pandemic affects everyone,regardless of their financial *** a result,diabetes is not a systemic disease which just involves people of low socioeconomic status.

关键词： Diabetes Incidence and prevalence Diabetes mellitus

Chiglitazar and Thiazolidinedione in patients with type 2 diabetes:Which is better?

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World Journal of Diabetes 2024年第3期15卷 565-567页

作者： kotha Sugunakar Reddy Archana Gaur Sakthivadivel Varatharajan arvind kumar morya Department of General Medicine All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Physiology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Medicine All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

This published Meta-Analysis by Lin et al is an indirect comparison between two drugs Chiglitazar and Thiazolidinedione which are commonly used for glycemic control in type-Ⅱ diabetes *** terms of safety and efficacy... 详细信息

关键词： Type-Ⅱdiabetes mellitus Glucose intolerance Hyperglycemia Research methodology

Bidirectional link between periodontitis and systemic inflammation in diabetic retinopathy

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World Journal of Diabetes 2024年第7期15卷 1651-1653页

作者： Prateek Nishant Sony Sinha Ranjeet kumar Sinha arvind kumar morya Department of Ophthalmology ESIC Medical CollegePatna 801103BiharIndia Department of Ophthalmology-Vitreo-Retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatna 801507BiharIndia Department of Community Medicine Patna Medical CollegePatna 800004BiharIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

Periodontitis is independently associated with numerous lifestyle *** patients have approximately threefold increased odds of periodontitis,which in turn increases the risk of systemic *** study by Thazhe Poyil et al is an effort to establish the inflammatory link between diabetic retinopathy(DR)and periodontitis based on the periodontal inflamed surface area in diabetic patients with and without *** further advance the study,we suggest refining the eligibility criteria to explicitly state the clinical correlates of periodontitis and DR,larger sample size and improved sampling methodology,matching of baseline characteristics of the two groups,as well as improved statistical approach and interpretation of the study *** of hemoglobin A1c(HbA1c)in studies comparing type 2 diabetes mellitus patients with DR of matched severity with and without periodontitis could provide a clearer picture of whether HbA1c level is indeed influenced by periodontitis.

关键词： Glucose intolerance Hyperglycemia Inflammation Research methodology Vision

Nutrition interventions and clinical outcomes of pregnant women with gestational diabetes mellitus: More than meets the eye

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World Journal of Diabetes 2024年第1期15卷 126-128页

作者： Sony Sinha Prateek Nishant Ranjeet kumar Sinha arvind kumar morya Ripunjay Prasad Department of Ophthalmology-Vitreo-Retina Neuro-Ophthalmology and OculoplastyAll India Institute of Medical SciencesPatnaPatna 801507BiharIndia Department of Ophthalmology ESIC Medical CollegePatnaPatna 801103BiharIndia Department of Community Medicine Patna Medical CollegePatna 800004BiharIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology RP Eye InstituteDelhi 110001DelhiIndia

In the retrospective study by Luo et al regarding clinical outcomes in gestational diabetes mellitus(GDM),the results are statistically significant in favour of the benefits of individualized nutrition interventions enumerated *** study has provided important evidence to improve maternal and child health in the Asian *** methods,however,appear to have considerable limi-tations,wherein the time point of diagnosis of GDM,severity of GDM,selection bias,compliance to therapy,important maternal covariates,observable microvascular abnormalities and the confounding effect of added insulin have not been *** have provided suggestions to improve the external validity of the study,including the use of Equator Network reporting guidelines and inclusion of overweight and obese patients in future studies.

关键词： Glucose intolerance Hyperglycemia Obesity Pregnancy Research methodology