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Mechanism of microbial spore inactivation through electromagnetic radiations:a review

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Journal of Future Foods 2024年第4期4卷 324-334页

作者： Piyush Sharma arun Prasath Venugopal Parag Prakash Sutar Hong-wei Xiao Qi Zhang Deparment of Food Process Engineering.National Institute of Techmology Rourkela Odisha 769008India College of Engineering China Agriculural UniversityBeijing 100083China School of Mechanical Engineering Yangzhou UTniversiny Yangzhou 225002China

Spores are the biological structures formed out of sporulation from vegetative cells in adverse *** tolerant to many extreme environment and conditions,they escape and survives critical processing steps in the food industry that poses food and health safety problems,as is evident from the increase in reports of food-bome outbreaks due to *** radiation(EM)is used for rapid decontamination and sterilization purposes in the food *** studies have reported a greater reduction in spore population upon irradiation with EM rays due to its impact on genomic material and other components of spores that destabilises overall structue and brings clonogenic death However,there is scattered literature regarding the mechanism of its inactivation and resistance against such *** review attempts to concisely evaluate the potential of electromagnetic radiations in spore inactivation and details its mechanism through a collective study of scientific results and *** also briefs about the process of sporulation,the structure of spores and the role of its components in the resistance of spores to *** studies,which demonstrated that combining various EM treatments might be an effective way for inactivation of spores,were discussed in detail.

关键词： Spore structure Electromagnetic radiations Mechanism of inactivation Damage resistance

Development,validation,and transportability of several machine-learned,non-exercise-based VO_(2max)prediction models for older adults

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Journal of Sport and Health Science 2024年第5期13卷 611-620页

作者： Benjamin T.Schumacher Michael J.LaMonte Andrea Z.LaCroix Eleanor M.Simonsick Steven P.Hooker Humberto Parada Jr. John Bellettiere arun Kumar Herbert Wertheim School of Public Health and Human Longevity Science University of California San DiegoLa JollaCA 92093USA Department of Epidemiology and Environmental Health School of Public Health and Health ProfessionsUniversity at BuffaloState University of New YorkBuffaloNY 14214USA Translational Gerontology Branch Intramural Research ProgramNational Institute on AgingNational Institutes of HealthBaltimoreMD 21225USA College of Health and Human Services San Diego State UniversitySan DiegoCA 92182USA Division of Epidemiology and Biostatistics School of Public HealthSan Diego State UniversitySan DiegoCA 92182USA University of California San Diego Moores Cancer Center La JollaCA 92093USA Computer Science and Engineering and Halicioglu Data Science Institute University of California San DiegoLa JollaCA 92093USA

Background:There exist few maximal oxygen uptake(VO_(2max))non-exercise-based prediction equations,fewer using machine learning(ML),and none specifically for older *** direct measurement of VO_(2max)is infeasible in large epidemiologic cohort studies,we sought to develop,validate,compare,and assess the transportability of several ML VO_(2max)prediction ***:The Baltimore Longitudinal Study of Aging(BLSA)participants with valid VO2_(max)tests were included(n=1080).Least absolute shrinkage and selection operator,linear-and tree-boosted extreme gradient boosting,random forest,and support vector machine(SVM)algorithms were trained to predict VO_(2max)*** developed these algorithms for:(a)the overall BLSA,(b)by sex,(c)using all BLSA variables,and(d)variables common in aging ***,we quantified the associations between measured and predicted VO_(2max)and ***:The age was 69.0±10.4 years(mean±SD)and the measured VO_(2max)was 21.6±5.9 mL/kg/*** absolute shrinkage and selection operator,linear-and tree-boosted extreme gradient boosting,random forest,and support vector machine yielded root mean squared errors of 3.4 mL/kg/min,3.6 mL/kg/min,3.4 mL/kg/min,3.6 mL/kg/min,and 3.5 mL/kg/min,*** quartiles of measured VO_(2max)showed an inverse gradient in mortality *** VO_(2max)variables yielded similar effect estimates but were not robust to ***:Measured VO_(2max)is a strong predictor of *** ML can improve the accuracy of prediction as compared to simpler approaches but estimates of association with mortality remain sensitive to *** studies should seek to reproduce these results so that VO_(2max),an important vital sign,can be more broadly studied as a modifiable target for promoting functional resiliency and healthy aging.

关键词： Cardiorespiratory fitness Prediction algorithms Epidemiology Mortality

Old-growth mixed dipterocarp forests show variable losses and gains in aboveground biomass and standing carbon over forty years

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Forest Ecosystems 2024年第1期11卷 14-23页

作者： Sisira Ediriweera Champika Bandara Tithira Lakkana Shanika Jayasinghe David Woodbury arun Dayanandan B.M.P.Singhakumara Xiangcheng Mi I.A.U.N.Gunatilleke C.V.S.Gunatilleke Mark SAshton Department of Science and Technology Uva Wellassa UniversityBadullaSri Lanka The Forest School Yale School of the EnvironmentYale UniversityNew HavenCT06511USA Department of Forestry and Environmental Science University of Sri JayewardenepuraNugegodaSri Lanka State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing100093China Botany Department University of PeradeniyaPeradeniyaSri Lanka

Background:No studies have documented long-term trends in aboveground biomass(AGB)for mixed-dipterocarp forests(MDF),the dominant rain forest type in tropical wet equatorial *** our study,we sought to document such trends over forty years across three sites representing lowland to lower montane ***:To do this,we established fifty 100 m×25 m plots in 1978 across three sites sampled along an elevation gradient,identified as mature old-growth *** measured trees for diameter at breast height that we identified to species and *** took wood samples to calculate species wood-specific *** re-measured plots in 1998 and again in ***:We show standing AGB for all sites combined to be 517.52 Mg·ha^(-1)in 1978,but this declined by 17%over 40 years to 430.11 Mg·ha^(-1).No differences exist among sites in AGB primarily because of considerable within site variation;but interactions of time with site show declines across sites were not uniform,one remained about the *** few species represented a high proportion of the AGB with the top five species comprising between 34%and 65%,depending upon site and year *** species,Mesua nagassarium,represented a disproportionately large amount of AGB and decline over time,particularly at the low elevation ***:Our results are directly relevant to estimating AGB and standing carbon sequestered in *** study is the first to demonstrate varying but overall,declining trends in amounts of AGB among forests making predictions of biomass and standing carbon in MDF difficult over wide regions.

关键词： Western ghats Shorea spp. Southeast Asia Sri Lanka Tropical rain forest Wood specific gravity

Spatial and Contextual Path Network for Image Inpainting

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Intelligent Automation & Soft Computing 2024年第2期39卷 115-133页

作者： Dengyong Zhang Yuting Zhao Feng Li arun Kumar Sangaiah Hunan Provincial Key Laboratory of Intelligent Processing of Big Data on Transportation Changsha University of Science and TechnologyChangsha410114China School of Computer and Communication Engineering Changsha University of Science and TechnologyChangsha410114China International Graduate Institute of AI National Yunlin University of Science and TechnologyYunlinTaiwan Department of Electrical and Computer Engineering Lebanese American UniversityByblosLebanon

Image inpainting is a kind of use known area of information technology to repair the loss or damage to the *** feature extraction is the core of image *** enough space for information and a larger receptive field is very important to realize high-precision image ***,in the process of feature extraction,it is difficult to meet the two requirements of obtaining sufficient spatial information and large receptive fields at the same *** order to obtain more spatial information and a larger receptive field at the same time,we put forward a kind of image restoration based on space path and context path *** the space path,we stack three convolution layers for 1/8 of the figure,the figure retained the rich spatial *** the context path,we use the global average pooling layer,where the accept field is the maximum of the backbone network,and the pooling module can provide global context information for the maximum accept *** order to better integrate the features extracted from the spatial and contextual paths,we study the fusion module of the two *** fusionmodule first path output of the space and context path,and then through themass normalization to balance the scale of the characteristics,finally the characteristics of the pool will be connected into a feature vector and calculate the weight *** of images in order to extract context information,we add attention to the context path refinement *** modules respectively from channel dimension and space dimension to weighted images,in order to obtain more effective *** show that our method is better than the existing technology in the quality and quantity of themethod,and further to expand our network to other inpainting networks,in order to achieve consistent performance improvements.

关键词： Image inpainting attention deep learning convolutional network

Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 699-715页

作者： Ankit Agarwal Sagnik Biswas Shekhar Swaroop Arnav Aggarwal Ayush Agarwal Gautam Jain Anshuman Elhence arun Vaidya Amit Gupte Ravi Mohanka Ramesh Kumar Ashwani Kumar Mishra Shivanand Gamanagatti Shashi Bala Paul Subrat Kumar Acharya Akash Shukla Shalimar Department of Gastroenterology and Human Nutrition All India Institute of Medical SciencesNew Delhi 110029DelhiIndia Department of Gastroenterology Seth Gordhandas Sunderdas Medical College and KEM HospitalMumbai 400012MaharashtraIndia Department of Gastroenterology Sir HN Reliance Foundation HospitalMumbai 400004India Department of Liver Transplant and HPB Sir HN Reliance Foundation HospitalMumbai 400004India Department of Gastroenterology All India Institute of Medical SciencesPatna 801507India Professor of Biostatistics National Drug Dependence Treatment Centre(NDDTC)All India Institute of Medical SciencesNew Delhi 110029India Department of Radiodiagnosis All India Institute of Medical SciencesNew Delhi 110029DelhiIndia

BACKGROUND There is scant literature on hepatocellular carcinoma(HCC)in patients with Budd-Chiari syndrome(BCS).AIM To assess the magnitude,clinical characteristics,feasibility,and outcomes of treatment in *** A total of 904 BCS patients from New Delhi,India and 1140 from Mumbai,India were *** prevalence and incidence of HCC were determined,and among patients with BCS-HCC,the viability and outcomes of interventional therapy were *** In the New Delhi cohort of 35 BCS-HCC patients,18 had HCC at index presentation(prevalence 1.99%),and 17 developed HCC over a follow-up of 4601 person-years,[incidence 0.36(0.22-0.57)per 100 person-years].BCS-HCC patients were older when compared to patients with BCS alone(P=0.001)and had a higher proportion of inferior vena cava block,cirrhosis,and long-segment vascular *** median alpha-fetoprotein level was higher in patients with BCS-HCC at first presentation than those who developed HCC at follow-up(13029 ng/mL vs 500 ng/mL,P=0.01).Of the 35 BCS-HCC,26(74.3%)underwent radiological interventions for BCS,and 22(62.8%)patients underwent treatment for HCC[transarterial chemoembolization in 18(81.8%),oral tyrosine kinase inhibitor in 3(13.6%),and transarterial radioembolization in 1(4.5%)].The median survival among patients who underwent interventions for HCC compared with those who did not was 3.5 years vs 3.1 mo(P=0.0001).In contrast to the New Delhi cohort,the Mumbai cohort of BCS-HCC patients were predominantly males,presented with a more advanced HCC[Barcelona Clinic Liver Cancer C and D],and 2 patients underwent liver *** HCC is not uncommon in patients with *** interventions and liver transplantation are feasible in select primary BCS-HCC patients and may improve outcomes.

关键词： Budd chiari syndrome Cancer Cirrhosis Thrombosis Liver Varices Transarterial chemoembolization Hepatic venous outflow tract obstruction

Climate change adaptation, greenhouse gas mitigation and economic profitability of conservation agriculture: Some examples from cereal systems of Indo-Gangetic Plains

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Journal of Integrative Agriculture 2015年第8期14卷 1524-1533页

作者： Tek B Sapkota M L Jat Jeetendra P Aryal R K Jat arun.khatri-chhetri International Maize and Wheat Improvement Center Borlaug Institute for South Asia Consultative Group of International Agricultural Research (CGIAR) Research Program on Climate Change Agriculture and Food Security (CCAFS) International Water Management Institute

Achieving sustainability of the cereal system in the Indo-Gangetic Plains（IGP）of India under progressive climate change and variability necessitates adoption of practices and technologies that increase food production,adaptation and mitigation in a sustainable *** paper examines conservation agriculture（CA）from the perspective of：（i）increased yield and farm income,（ii）adaptation to heat and water stresses,and（iii）reduction in greenhouse gas（GHGs）*** analyses and conclusions are based on the literature and evidences from a large number of on-station as well as farmers’field trials on CA in the cereal systems of *** analyses show that CA-based system substantially reduces the production cost（up to 23%）but produces equal or even higher than conventional system;thereby increasing economic profitability of production ***-based production systems also moderated the effect of high temperature（reduced canopy temperature by 1–4°C）and increased irrigation water productivity by 66–100%compared to traditional production systems thus well adapting to water and heat stress situations of *** continuous monitoring of soil flux of CO2,N2O and CH4 revealed that CA-based rice-wheat systems emit 10–15%less GHGs than conventional *** is the first time that CA and its components are synthesized and analyzed from food security-climate change *** this holistic analysis,we suggest that wide-scale promotion of suitable CA practices by integrating into national agriculture development strategy is a way forward to address food security,climate change adaptation and mitigation challenges faced by present agriculture.

关键词： zero-tillage residue retention climate change sustainability conservation agriculture

Paradigm shift in transfusion practices during early COVID-19 pandemic:A single center retrospective study

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World Journal of Virology 2024年第2期13卷 78-86页

作者： Sumukh arun Kumar Sushmita Prabhu Ankushi Sanghvi Maya Gogtay Mithil Gowda Suresh Harshit Khosla Yuvaraj Singh Ajay Kumar Mishra Susan George Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Hematology and Oncology University of Nebraska Medical CenterOmahaNE 68198United States Hospice and Palliative Care UTHSC and McGovern School of MedicineTexasTX 77030United States Department of Gastroenterology and Hepatology UMass Chan Medical SchoolWorcesterMA 01655United States Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States

BACKGROUND The advent of coronavirus disease 2019(COVID-19)unveiled the worst national blood crisis that the United States had witnessed in over a *** the pandemic influencing the different stages of the acquisition of blood products outside the hospital setting,we aimed to explore the possible barriers contributing to the shortage of blood products within the medical *** COVID era and pre-COVID *** We conducted a retrospective cross-sectional study on hospitalized patients distinguishing the pattern of blood transfusion during the COVID and pre-COVID era in a community *** was tabulated to include the number of red blood cell(RBC)transfusions and if transfusions met restrictive blood transfusion criteria as per institutional ***-square was applied to test the statistical association between qualitative *** t test and Mann Whitney U test were applied respectively to test the mean difference of quantitative *** A total of 208 patients were included in the study,of which 108 were during COVID era and 100 were during pre-COVID *** leading reason for admission in both the COVID era and pre-COVID era transfused patients was shortness of breath(53.7%and 36%P=0.001),followed by gastrointestinal bleeding(25.9%and 21%P=0.001).There was a higher percentage of RBC transfusions in the intensive care unit in the COVID-era group than in the pre-COVID era group(38.9%vs 22%,P=0.008).The restrictive transfusion criteria were met in 62%vs 79%in the COVID and pre-COVID eras,respectively(P=0.008).CONCLUSION The COVID-era group received RBC transfusions with less stringent adherence to restrictive blood transfusion practices in comparison to pre-COVID era group.

关键词： Blood transfusion Restrictive transfusion COVID-19 Pre-COVID-19 Blood shortage Pandemic

Mechanical and Physical Properties of Pineapple Leaf and Sun Hemp Fibre Reinforced Hybrid Natural Composite Fabricated by Compression Moulding Method

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Journal of Bionic Engineering 2022年第1期19卷 257-267页

作者： A.arun Premnath Centre for Composite Science and Tribology Sri Chandrasekharendra Saraswathi Viswa MahavidyalayaKanchipuramTamilnadu631561India

The implementation of natural fibres in polymer composites will result in biodegradable,low cost,recyclable materials for automobile and structural *** the process of making natural fibre composites viable in the global market,it is essential to understand its mechanical and physical *** the present investigation,mechanical and physical properties of pineapple Leaf(PALF)and Sun Hemp(SH)Fibre reinforced with epoxy matrix was studied in terms of weight(wt)%of fibre loading and chemical *** composites were fabricated by compression moulding technique with PALF fibre content varying from 10,15 and 20%of weight *** PALF and SHF were treated with NaOH solution for 1 h at room *** various mechanical properties such as tensile,compression,flexural and impact strength were measured as per ASTM *** density and water absorption were also measured to study the physical properties of the fabricated *** treated composites exhibit a rough surface because of the removal of the cellulose layer which results in better adhesion between the matrix/fibre interface than untreated *** NaOH treated fibres composites outperformed untreated fibre composites in terms of mechanical and physical properties except for impact *** morphological studies of the worn surfaces are examined using Scanning Electron Microscope(SEM).

关键词： Pineapple leaf fibre Compression moulding Mechanical properties Physical properties Morphological studies

Corrigendum to'Cancer chemotherapy and beyond:Current status,drug candidates,associated risks and progress in targeted therapeutics'[Genes&Diseases 10(2023)1367-1401]

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Genes & Diseases 2024年第4期11卷 426-427页

作者： Uttpal Anand Abhijit Dey Arvind K.Singh Chandel Rupa Sanyal Amarnath Mishra Devendra Kumar Pandey Valentina De Falco arun Upadhyay Ramesh Kandimalla Anupama Chaudhary Jaspreet Kaur Dhanjal Saikat Dewanjee Jayalakshmi Vallamkondu Jose M.Perez de la Lastra Department of Life Sciences Ben-Gurion University of the NegevBeer-Sheva 84105Israel Department of Life Sciences Presidency UniversityKolkataWest Bengal 700073India Center for Disease Biology and Integrative Medicine Faculty of MedicineThe University of TokyoTokyo 113-0033Japan Department of Botany Bhairab Ganguly College(affliated to West Bengal State University)KolkataWest Bengal 700056India Faculty of Science and Technology Amity Institute of Forensic SciencesAmity University Uttar PradeshNoida 201313India Department of Biotechnology School of Bioengineering and BiosciencesLovely Professional UniversityPhagwaraPunjab 144411India Institute of Endocrinology and Experimental Oncology(IEOS) National Research Council(CNR)Department of Molecular Medicine and Medical Biotechnology(DMMBM)University of Naples FedericoⅡNaples 80131Italy Department of Biochemistry School of Life SciencesCentral University of RajasthanBandar SindariKishangarhAjmerRajasthan 305817India CSiR-indian Institute of Chemical Technology HyderabadTelangana 500007India Department of Biochemistry Kakatiya Medical CollegeWarangalTelangana 506007India Orinin-BioSystems LE-52Lotus Road 4CHD CityKarnalHaryana 132001India Department of Computational Biology Indraprastha Institute of Information Technology Delhi(ⅢT-D)Okhla Industrial EstatePhaseⅢNew Delhi 110020India Advanced Pharmacognosy Research Laboratory Department of Pharmaceutical TechnologyJadavpur UniversityKolkata 700032India Department of Physics National Institute of Technology-WarangalWarangalTelangana 506004India Biotechnology of Macromolecules Research Group Instituto de Productos Naturales y AgrobiologiaIPNA-CSICSan Cristobal de La Laguna 38206TenerifeSpain

In the published article,there was an error in the affiliation information about the first author Uttpal Anand[a].Instead of"Department of Life Sciences,Ben-Gurion University of the Negev,Beer-Sheva 84105,Israel",it should be"CytoGene Research&Development LLP,K-51,UPSIDA Industrial Area,Kursi Road(Lucknow),***,225001,Uttar Pradesh,India".The authors would like to apologize for any inconvenience caused and state that this does not change the scientific conclusions of thearticle inanyway.

关键词： Cancer Cor targeted