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Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 699-715页

作者： Ankit Agarwal Sagnik Biswas Shekhar Swaroop Arnav Aggarwal Ayush Agarwal gautam Jain Anshuman Elhence arun Vaidya Amit Gupte Ravi Mohanka Ramesh Kumar Ashwani Kumar Mishra Shivanand Gamanagatti Shashi Bala Paul Subrat Kumar Acharya Akash Shukla Shalimar Department of Gastroenterology and Human Nutrition All India Institute of Medical SciencesNew Delhi 110029DelhiIndia Department of Gastroenterology Seth Gordhandas Sunderdas Medical College and KEM HospitalMumbai 400012MaharashtraIndia Department of Gastroenterology Sir HN Reliance Foundation HospitalMumbai 400004India Department of Liver Transplant and HPB Sir HN Reliance Foundation HospitalMumbai 400004India Department of Gastroenterology All India Institute of Medical SciencesPatna 801507India Professor of Biostatistics National Drug Dependence Treatment Centre(NDDTC)All India Institute of Medical SciencesNew Delhi 110029India Department of Radiodiagnosis All India Institute of Medical SciencesNew Delhi 110029DelhiIndia

BACKGROUND There is scant literature on hepatocellular carcinoma(HCC)in patients with Budd-Chiari syndrome(BCS).AIM To assess the magnitude,clinical characteristics,feasibility,and outcomes of treatment in *** A total of 904 BCS patients from New Delhi,India and 1140 from Mumbai,India were *** prevalence and incidence of HCC were determined,and among patients with BCS-HCC,the viability and outcomes of interventional therapy were *** In the New Delhi cohort of 35 BCS-HCC patients,18 had HCC at index presentation(prevalence 1.99%),and 17 developed HCC over a follow-up of 4601 person-years,[incidence 0.36(0.22-0.57)per 100 person-years].BCS-HCC patients were older when compared to patients with BCS alone(P=0.001)and had a higher proportion of inferior vena cava block,cirrhosis,and long-segment vascular *** median alpha-fetoprotein level was higher in patients with BCS-HCC at first presentation than those who developed HCC at follow-up(13029 ng/mL vs 500 ng/mL,P=0.01).Of the 35 BCS-HCC,26(74.3%)underwent radiological interventions for BCS,and 22(62.8%)patients underwent treatment for HCC[transarterial chemoembolization in 18(81.8%),oral tyrosine kinase inhibitor in 3(13.6%),and transarterial radioembolization in 1(4.5%)].The median survival among patients who underwent interventions for HCC compared with those who did not was 3.5 years vs 3.1 mo(P=0.0001).In contrast to the New Delhi cohort,the Mumbai cohort of BCS-HCC patients were predominantly males,presented with a more advanced HCC[Barcelona Clinic Liver Cancer C and D],and 2 patients underwent liver *** HCC is not uncommon in patients with *** interventions and liver transplantation are feasible in select primary BCS-HCC patients and may improve outcomes.

关键词： Budd chiari syndrome Cancer Cirrhosis Thrombosis Liver Varices Transarterial chemoembolization Hepatic venous outflow tract obstruction

Fragment emission and critical behavior in light and heavy charged systems

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Chinese Physics C 2021年第1期45卷 215-225页

作者： Samiksha Sood Rohit Kumar arun Sharma Sakshi gautam Rajeev K.Puri Department of Physics Panjab UniversityChandigarh 160014India Department of Physics G.D.College.BillawarJammu 185204India

We study the emission of fragments in central collisions of light and heavily charged systems of^4+Ar+^45 Sc and^s4Kr+^197 Au,respectively,using the Quantum Molecular Dynamics(QMD)model as the primary *** fragments are identified using an energy based clusterization algorithm,i.e.,the Simulated Annealing Clusterization Algorithm(SACA).The charge distributions of intermediate mass fragments[3≤Zf≤12]are fitted with power-law(∝Zf^-τ)and exp on ential(∝e^-λZf)fits in order to extract the parametersτandλ,whose minimum values are also sometimes linked with the onset of fragmentation or the critical point for a liquid-gas phase *** parameters such as the normalized second moment,,average size of the second largest cluster,phase separation parameter(Sp),bimodal parameter(P),information entropy(H),and Zipfs law are also analyzed to find the exact energy of the onset of *** detailed analysis predicts that an energy point exists between 20-23.1 MeV/nucleon,which is very close to the experimentally observed value of 23.9 MeV/nucleon for the^40Ar+^45Sc *** also find that the critical energy deduced using Zipfs law is higher than those predicted from other critical ***,no minimum is found for t values of the highly charged system of^84Kr+^197Au,in agreement with experimental findings and various theoretical *** observe that the QMD+SACA model calculations are in agreement with the experimental *** agreement supports our results regarding the energy point of the liquid-gas phase transition and the onset of fragmentation.

关键词： heavy-ion collisions transport model clusterization algorithm Monte-Carlo technique li・quid-gas phase transition

Big Data Analytics Using Swarm-Based Long Short-Term Memory for Temperature Forecasting

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Computers, Materials & Continua 2022年第5期71卷 2347-2361页

作者： Malini M.Patil P.M.Rekha arun Solanki Anand Nayyar Basit Qureshi JSS Academy of Technical Education Bengaluru560060India gautam Buddha University Greater Noida201312India Graduate School Duy Tan UniversityDa Nang550000Vietnam Faculty of Information Technology Duy Tan UniversityDa Nang550000Vietnam College of Computer&Info Sc Prince Sultan UniversitySaudi Arabia

In the past few decades,climatic changes led by environmental pollution,the emittance of greenhouse gases,and the emergence of brown energy utilization have led to global *** warming increases the Earth’s temperature,thereby causing severe effects on human and environmental conditions and threatening the livelihoods of millions of *** warming issues are the increase in global temperatures that lead to heat strokes and high-temperature-related diseases during the summer,causing the untimely death of thousands of *** forecast weather conditions,researchers have utilized machine learning algorithms,such as autoregressive integrated moving average,ensemble learning,and long short-term memory *** techniques have been widely used for the prediction of *** this paper,we present a swarm-based approach called Cauchy particle swarm optimization(CPSO)to find the hyperparameters of the long shortterm memory(LSTM)*** hyperparameters were determined by minimizing the LSTM validationmean square error *** optimized hyperparameters of the LSTM were used to forecast the temperature of Chennai *** proposed CPSO-LSTM model was tested on the openly available 25-year Chennai temperature *** experimental evaluation on MATLABR2020a analyzed the root mean square error rate and mean absolute error to evaluate the forecasted *** proposed CPSO-LSTM outperforms the traditional LSTM algorithm by reducing its computational time to 25 min under 200 epochs and 150 hidden neurons during *** proposed hyperparameter-based LSTM can predict the temperature accurately by having a root mean square error(RMSE)value of 0.250 compared with the traditional LSTM of 0.35 RMSE.

关键词： Climatic change big data temperature forecasting swarm intelligence deep learning

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喜马拉雅中部榴辉岩相变质作用的条件和时代

喜马拉雅中部榴辉岩相变质作用的条件和时代

Wheat Stripe Rust Virulence and Varietal Resistance in the Foot Hill Himalayas of Nepal

2018年中国地球科学联合学术年会

作者：王佳敏吴福元 gautam Khanal 杨雷刘小驰中国科学院地质与地球物理研究所岩石圈演化国家重点实验室

喜马拉雅是世界上最年轻和典型的陆陆碰撞造山带,从中揭示的造山带地壳结构和地质过程可以丰富板块构造理论,为其他碰撞造山带的研究提供示范作用。运用高压变质岩石的压力-温度-时间轨迹可以反演造山带的构造-热演化过程。最近几年陆... 详细信息

喜马拉雅是世界上最年轻和典型的陆陆碰撞造山带,从中揭示的造山带地壳结构和地质过程可以丰富板块构造理论,为其他碰撞造山带的研究提供示范作用。运用高压变质岩石的压力-温度-时间轨迹可以反演造山带的构造-热演化过程。最近几年陆续在喜马拉雅中部的定结、不丹、arun河谷等地报道了榴辉岩,为揭示喜马拉雅造山深部过程提供了宝贵的岩石学素材。但由于这些榴辉岩在折返过程中经历了麻粒岩相变质叠加,其榴辉岩相变质作用的条件和时代有待恢复。本文对藏南定结地区高喜马拉雅结晶岩系内出露的榴辉岩及其围岩进行了详细的岩相学观察、温度压力计算、锆石和榍石年代学,并进一步对围岩薄片中的独居石进行岩石年代学研究,试图恢复其榴辉岩相及麻粒岩相变质叠加的条件和时代。研究区榴辉岩的压力峰期矿物主要以绿辉石包裹体(Jd～29%)形式存在于石榴石中,基质中绿辉石已分解为单斜辉石+富钠斜长石的后成合晶,变质条件应为>16 kbar和30 Ma。以上结果表明,喜马拉雅中部的印度大陆地壳可能经历了与喜马拉雅西部相似的早期俯冲过程,其岩石学及年代学差异主要由不同的折返过程导致。在折返过程中,喜马拉雅中部的印度大陆地壳卷入了加厚地壳山根,发生麻粒岩相高温变质叠加,抹去了榴辉岩相的变质条件和时代信息。从喜马拉雅揭示的两期变质事件和地质过程可能广泛存在于其他造山带中,并是众多古老的大陆碰撞造山带中广泛发育高压麻粒岩而未发现榴辉岩的重要原因。

关键词：喜马拉雅榴辉岩麻粒岩相变质叠加岩石年代学 P-T-t轨迹

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Journal of Agricultural Science and Technology(B) 2015年第7期5卷 477-485页

作者： Sarala Sharma Etienne Duveiller Chandra Bahadur Karki Dhruba Bahadur Thapa Ram Chandra Sharma arun Kumar Joshi Plant Pathology Division Nepal Agricultural Research Council Lalitpur 44700 Nepal CIMMYT Global Wheat Program Apdo Postal 6-641 Mexico 06600 DF Mexico Agriculture Botany Division Nepal Agricultural Research Council Lalitpur 44700 Nepal ICARDA Central Asia and the Caucasus Regional Program Tashkent 10000 Uzbekistan CIMMYT South Asia Regional Office Kathmandu 44600 Nepal