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Nd^(3+)-sensitized upconversion nanoparticle coated with antimony shell for bioimaging and photothermal therapy in vitro using single laser irradiation

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Journal of Rare Earths 2022年第6期40卷 862-869,I0001页

作者： Solomon Tiruneh Dibaba Yao Xie Wensong Xi artur Bednarkiewicz Wei Ren Lining Sun Research Center of Nano Science and Technology College of SciencesShanghai UniversityShanghai 200444China Physics Department International Centre for Quantum and Molecular StructuresShanghai UniversityShanghai 200444China Applied Physics Department School of Applied Natural ScienceAdama Science and Technology UniversityAdama 1888Ethiopia School of Environmental and Chemical Engineering Shanghai UniversityShanghai 200444China Institute of Low Temperature and Structure Research Polish Academy of Sciences50-422 WroclawPoland

Combining treatment and diagnosis,called theranostics,which is achieved within single nanoparticle is an ultimate goal of many ***,we developed a new nanotheranostic agent-Nd^(3+)-sensitized upconversion nanoparticles core for dual modal imaging(i.e.,upconversion luminescence imaging and magnetic resonance imaging) and antimony nanoshell for photothermal therapy(PTT).The core-shellshell upconversion nanoparticles(NaYF_(4):Yb,Er@NaYF_(4):Yb,Nd@NaGdF_(4):Nd,named as UCNP) were firstly synthesized using thermal decomposition method and then were coated by antimony shell over the surface of UCNP using simple cost and time effective new ***,the surface of UCNP@Sb nanostructures was modified with DSPE-PEG in order to enhance the water solubility and *** final nanotheranostic agent,named as UCNP@Sb-PEG,exhibits very low toxicity,good biocompatibility,very good photothermal therapeutic effect,and efficient upconversion luminescence(UCL) imaging of HeLa cells under only one laser(808 nm) *** antimony shell is quenching the upconversion emission in pristine nanotheranostic agent,but interestingly,the UCL intensity of the agent recovers progressively under 808 nm laser irradiation due to light induced degradability of antimony ***,high longitudinal relaxivity(r_(1)) obtained from the experiment approves excellent potential of the nanotheranostic agent for T_(1)-weighted magnetic resonance imaging application.

关键词： Rare earths Upconversion luminescence Nanotheranostic agent Antimony shell Bioimaging Photothermal therapy

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The role of arabinogalactan proteins(AGPs)in fruit ripening—a review

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Horticulture Research 2020年第1期7卷 422-433页

作者： Agata Leszczuk Panagiotis Kalaitzis Konstantinos N.Blazakis artur Zdunek Institute of Agrophysics Polish Academy of SciencesDoświadczalna 420-290 LublinPoland Department of Horticultural Genetics and Biotechnology Mediterranean Agronomic Institute of ChaniaChaniaP.O.Box 85Chania 73100Greece

Arabinogalactan proteins(AGPs)are proteoglycans challenging researchers for ***,despite the extremely interesting polydispersity of their structure and essential application potential,studies of AGPs in fruit are limited,and only a few groups deal with this scientific ***,we summarise the results of pioneering studies on AGPs in fruit tissue with their structure,specific localization pattern,stress factors influencing their presence,and a focus on recent *** discuss the properties of AGPs,i.e.,binding calcium ions,ability to aggregate,adhesive nature,and crosslinking with other cell wall components that may also be implicated in fruit *** aim of this review is an attempt to associate well-known features and properties of AGPs with their putative roles in fruit *** putative physiological significance of AGPs might provide additional targets of regulation for fruit developmental programme.A comprehensive understanding of the AGP expression,structure,and untypical features may give new information for agronomic,horticulture,and renewable biomaterial applications.

关键词： AGPs structure culture

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Biofunctionalized upconverting CaF2：Yb,Tm nanoparticles for Candida albicans detection and imaging

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Nano Research 2017年第10期10卷 3333-3345页

作者： Malgorzata Misiak Michal Skowicki Tomasz Lipinski Agnieszka Kowalczyk Katarzyna Prorok Sebastian Arabasz artur Bednarkiewicz Wroctaw Research Centre EIT+ ul. Stablowicka 147 54-066 Wroclaw Poland Insitute of Immunology and Experimental Therapy Polish Academy of Sciences ul. Rudolfa Weigla 12 53-114 Wroctaw Poland Centre of Polymer and Carbon Materials Polish Academy of Sciences M. Curie-Sklodowskiej 34 41-819 Zabrze Poland Institute of Low Temperature and Structure Research Polish Academy of Sciences ul. Okolna 2 50-422 Wroctaw Poland

Versatile optimization of the synthesis method and composition of Yb^3＋ and Tm^3＋ co-doped CaF2 nanoparticles as well as a novel biofunctionalization method were developed and evaluated. Through multistep synthesis, the luminescence intensity of the Tm3. activator was enhanced by more than 10-fold compared to standard one-step synthesis. The proposed methods were used to homogenously distribute the doping ions within the nanoparticle＇s volume and thus reduce luminescence quenching. Optimization of dopant ions concentration led to the selection of the most efficient visible and near-infrared up-converting nanoparticles, which were CaF2 doped with 10% Yb^3＋ 0.05% Tm^3＋ and 20% Yb3. 0.5% Tm^3＋, respectively. To illustrate the suitability of the synthesized nanoparticles as bio-labels, a dedicated biofunctionalization method was used, and the nanoparticles were applied for labeling and imaging of Candida albicans cells. This method shows great promise because of extremely low background and high specificity because of the presence of the attached molecules.

关键词： up-conversion luminescence nanomaterials fluoride nanoparticles bioimaging

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Modeling antiphase boundary energies of Ni_(3)Al-based alloys using automated density functional theory and machine learning

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npj Computational Materials 2022年第1期8卷 757-766页

作者： Enze Chen artur Tamm Tao Wang Mario E.Epler Mark Asta Timofey Frolov Department of Materials Science and Engineering University of CaliforniaBerkeleyCA94720USA Materials Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCA94720USA Materials Science Division Lawrence Livermore National LaboratoryLivermoreCA94550USA Carpenter Technology Corporation PhiladelphiaPA19103USA

Antiphase boundaries(APBs)are planar defects that play a critical role in strengthening Ni-based superalloys,and their sensitivity to alloy composition offers a flexible tuning parameter for alloy ***,we report a computational workflow to enable the development of sufficient data to train machine-learning(ML)models to automate the study of the effect of composition on the(111)APB energy in Ni_(3)Al-based *** employ ML to leverage this wealth of data and identify several physical properties that are used to build predictive models for the APB energy that achieve a cross-validation error of 0.033 J m^(−2).We demonstrate the transferability of these models by predicting APB energies in commercial ***,our use of physically motivated features such as the ordering energy and stoichiometry-based features opens the way to using existing materials properties databases to guide superalloy design strategies to maximize the APB energy.

关键词： Ni_(3)Al alloy superalloy

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A Lattice Boltzmann Study of Phase Separation in Liquid-Vapor Systems with Gravity

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Communications in Computational Physics 2010年第2期7卷 350-361页

作者： artur Cristea Giuseppe Gonnella Antonio Lamura Victor Sofonea Center for Fundamental and Advanced Technical Research Romanian AcademyBd.Mihai Viteazul 24300223 Timi¸soaraRomania Dipartimento di Fisica Universita di Bari and INFNSezione di BariVia Amendola 17370126 BariItaly Istituto Applicazioni Calcolo CNRVia Amendola 122/D70126 BariItaly

Phase separation of a two-dimensional van der Waals fluid subject to a grav-itational force is studied by numerical simulations based on lattice Boltzmann methodsimplemented with a finite difference scheme. A growth e... 详细信息

关键词： Lattice Boltzmann phase separation liquid-vapor gravity

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Hydrodynamic parameters in a flood impacted boulder block ramp： Krzczonówka mountain stream, Polish Carpathians

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Journal of Mountain Science 2018年第11期15卷 2335-2346页

作者： RADECKI-PAWLIK artur PLESINSKI Karol RADECKI-PAWLIK Bartosz KUBON Piotr MANSON Russell Institute of Structural Mechanics Cracow University of Technology Krakow 31-155 Poland Department of Hydraulics Engineering and Geotechnics University of Agricultural in Krakow Krakow 30-059Poland School of Natural Sciences and Mathematics Stockton University Galloway NJ 08205-9441 USA

Boulder block ramps are river engineering structures used to stabilise river beds. Block ramps provide a semi-natural and aesthetically pleasing solution to certain river engineering problems in mountain streams. When constructing block ramps,one can use the dissipative behaviour of large macroroughness elements randomly placed on the river bed to enhance fish migration in an upstream direction thus, in this sense, meeting the requirements of the EU Water Framework Directive. Block ramps are often designed and constructed to replace damaged drop hydraulic structures in the channels of mountain streams. This paper investigates the resilience of a particular block ramp placed in the Krzczonówka stream(Polish Carpathians) in terms of the engineering design function and its durability against damaging. A hydrodynamic analysis of a block ramp is presented before and after a flood event that changed the configuration of the blocks. The seminatural unstructured hydraulic structure was built on the Krzczonowka stream to protect gas pipes which are located beneath it. As a result of several floods, the boulder block chute described in this paper was damaged, and some boulders were dislodged and transported downstream. Our post-flood investigations of bathymetry and velocity revealed that even damaged boulder blocks, removed from the chute and displaced downstream of the structure, still provide significant energy dissipation of the flowing water. The novel of our paper is for the first time showing very detailed analysis of unstructured block ramp hydrodynamics parameters done in the *** the novel finding of our investigations shows that before and after the flood event the unstructured block ramp structure, is still fish friendly in terms of hydrodynamics.

关键词： Boulder ramp Mountain stream Hydrodynamic Ramp chute

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Towards the automation of book typesetting

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Visual Informatics 2023年第2期7卷 1-12页

作者： Sérgio M.Rebelo Tiago Martins Diogo Ferreira artur Rebelo University of Coimbra Centre for Informatics and Systems of the University of CoimbraDepartment of Informatics EngineeringCoimbraPortugal

This paper proposes a generative approach for the automatic typesetting of books in desktop *** presented system consists in a computer script that operates inside a widely used design software tool and implements a generative process based on several typographic rules,styles and principles which have been identified in the *** performance of the proposed system is tested through an experiment which included the evaluation of its outputs with *** results reveal the ability of the system to consistently create varied book designs from the same input content as well as visually coherent book designs with different contents while complying with fundamental typographic principles.

关键词： Design tools Data-driven design Generative design Graphic design Typography

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Diverse phenotype of Méenière’s disease associated with family history,thyroid disorder,migraine and associated disorders

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Journal of Otology 2024年第4期19卷 185-192页

作者： Ilmari Pyykkö Vinay Jing Zou artur Vetkas Vinaya Manchaiah Hearing and Balance Research Unit Field of OtolaryngologySchool of MedicineFaculty of Medicine and Health TechnologyTampere UniversityTampereFinland Audiology Group Department of Neuromedicine and Movement SciencesNorwegian University of Science and TechnologyTrondheimNorway Department of Otolaryngology-Head and Neck Surgery University of Colorado School of MedicineAuroraCOUSA Department of Otolaryngology-Head and Neck Surgery Center for Otolaryngology-Head&Neck Surgery of the Chinese PLAChanghai HospitalSecond Military Medical UniversityShanghaiChina Neurology Clinic Department of NeurosurgeryTartu University HospitalTartuEstonia UCHealth Hearing and Balance University of Colorado HospitalAuroraCOUSA Virtual Hearing Lab Collaborative Initiative Between University of Colorado School of Medicine and University of PretoriaAuroraCOUSA Department of Speech-Language Pathology and Audiology University of PretoriaPretoriaSouth Africa Department of Speech and Hearing School of Allied Health SciencesManipal UniversityManipalKarnatakaIndia

Objective:To better understand the clinical phenotype of Méenière’s disease(MD),we examined family history,thyroid disorder,migraine,and associated disorders in complaints of people living with ***:We designed the study as a retrospective and examined data gathered from 912 participants with *** data were originally collected by the Finnish M′eni`ere Federation(FMF).The survey data included individual case histories for environmental factors,comorbidities,disease-specific complaints,impact-related questions,cognitive complaints,health-related quality of life(HRQoL),and sense of coherence(SOC).Results:We observed significant differences between those with and without sporadic occurrence,family history,thyroid disorder,and migraine-associated *** history explained 20%of variability in patient *** with a family history of MD whose disease started at younger age experienced balance problems,more severe vertigo spells,more severe vestibular drop attacks(VDA),and less nausea,although they had good *** disorder explained 14%of variability in patient *** patients with a thyroid disorder comorbidity suffered more often from constant dizziness,balance problems,greater impact of hearing problems,cognitive complaints,and poor *** explained 12%of variability in patients’complaints and was associated with poor SOC and cognitive balance *** patients with both thyroid disorder and migraine used antidepressants more often than other *** regression analysis showed comorbidities of ischemic brain disorder(among 7.1%),kidney insufficiency(among 1.2%),and diabetes(among 7.3%)had statistically significant but restricted association with balance and gait problems,VDA,and reduced ***:Family history of MD and thyroid disorder or migraine comorbidities in MD influence the complaint pattern and partially explain complex symptom profiles,including symptoms of cognitive *** p

关键词： Méenière’s disease Migraine Thyroid Family history Hereditary

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Effect of the C:N:P ratio on the denitrifying dephosphatation in a sequencing batch biofilm reactor(SBBR)

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Journal of Environmental Sciences 2015年第12期27卷 119-125页

作者： artur Mielcarek Joanna Rodziewicz Wojciech Janczukowicz Arthur J.Thornton Tomasz Józwiak Paula Szymczyk University of Warmia and Mazury in Olsztyn Department of Environment Engineering ul. Warszawska 117a Olsztyn 10-719 Poland. Atkins Woodcote Grove Ashley Road Epsom KT18 United Kingdom

A series of investigations were conducted using sequencing batch biofilm reactor（SBBR） to explore the influence of C：N：P ratio on biological dephosphatation including the denitrifying dephosphatation and the denitrification *** in the reactor occurred mainly in the form of a biofilm attached to completely submerged *** acid was used as the source of organic carbon.C：N：P ratios have had a significant effect on the profiles of phosphate release and phosphate uptake and nitrogen *** highest rates of phosphate release and phosphate uptake were recorded at the C：N：P ratio of 140：70：*** C：N ratio of 2.5：1 ensured complete *** highest rate of denitrification was achieved at the C：N：P ratio of 140：35：*** increase of nitrogen load caused an increase in phosphates removal until a ratio C：N：P of 140：140：*** of the biofilm exposed to alternate conditions of mixing and aeration exhibited enhanced intracellular accumulation of ***,the structure of the biofilm encouraged anaerobic-aerobic as well as anoxic-anaerobic and absolutely anaerobic conditions in a *** heterogeneous conditions in the presence of nitrates may be a significant factor determining the promotion of denitrifying polyphosphate accumulating organism（DNPAO） development.

关键词： Wastewater treatment Sequencing batch biofilm reactor Nitrogen and phosphorus removal Enhanced intracellular polyphosphate accumulation Denitrifying dephosphatation Denitrification and dephosphatation rates

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A potential engineering solution to facilitate upstream movement of fish in mountain rivers with weirs:Southern Carpathians,the Azuga River

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Journal of Mountain Science 2020年第3期17卷 501-515页

作者： Razvan VOICU artur RADECKI-PAWLIK Tomasz TYMINSKI Marian MOKWA Robbin SOTIR Liliana VOICU Ecohidrology and Water Quality Protection Service National Institute of Hydrology and Water ManagementBucharest 013686Romania Division of Structural Mechanics and Material Mechanics Faculty of Civil EngineeringCracow University of TechnologyKrakow 31-155Poland Institute of Environmental Engineering Wroclaw University of Environmental and Life SciencesWroclaw 50-363Poland Robbin Sotir&Associates Inc.3602 Ernest W.Barrett Parkway MariettaGeorgia 30064-2732USA

An important aspect in the restoration of longitudinal connectivity in rivers and streams is the implementation of fish migration systems at the upstream of the functional hydraulic structures(weirs,drop structures or river sills).The diversity of these existing structures as well as the different locations of these weirs within the river,watershed and riparian zone challenge the design engineers to find new holistic solutions for fish migration *** Azuga River study area requires a new synergistic fish migration design *** a mountain area,rapid increase in water level is quite frequent,especially after heavy or prolonged rainfalls and during spring snow ***,it is necessary to design a specific system for fish migration to meet this location’s *** to the characteristics in this location of the Azuga river,the classic fish migration systems would not be *** indigenous/mountain trout is considered as the target species in this *** this is a good swimming species,the use of classical systems could,due to exhaustion,prevent and/or reduce the movement of fish upstream of the two weirs(also known as river sills).This new,comprehensive solution,presented in this paper includes:(i)the restoration and stabilization works of the right bank in the weir study area by using biotechnical measures and(ii)the upstream migration system itself-for supporting the migration of fish on the Azuga River.

关键词： Weir Fish migration system Brown trout Mountainriver Soilbioengineering Connectivity

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