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Genealogy and phylogeography of Cyprinid fish Labeo rohita （Hamilton, 1822） inferred from ATPase 6 and 8 mitochondrial DNA gene analysis

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Current Zoology 2014年第4期60卷 460-471页

作者： Rupesh K. LUHARIYA Kuldeep K. LAL Rajeev K. SINGH Vindhya MOHINDRA arti gupta Prachi MASIH Arvind K. DWIVEDI Rakhi DAS U. K. CHAUHAN J. K. JENA National Bureau ofFish Genetic Resources (ICAR) Lucknow- 226 002 UP India School of Environmental Sciences APS University Rewa- 486 003 MP India

ATPase 6/8 gene （842 bp） of mitochondrial DNA was sequenced in Labeo rohita samples （n = 253） collected from nine rivers belonging to four river basins; Indus, Ganges, Brahmaputra and Mahanadi. Analysis revealed 44 haplotypes with high haplotype diversity （Hd） 0.694 and low nucleotide diversity （π） 0.001. The within population variation was larger （83.44%） than among population differences （16.56%）. The mean Fsv value （0.166; P 〈 0.05） for overall populations revealed moderate level of genetic structuring in the wild L. rohita populations. The haplotype network presented a single clade for wild L. rohita population, from different rivers. Negative values for Fu＇s index （Fs）, mismatch distribution analysis indicated period of expansion in L. rohita population. The time after recent expansion was estimated for each population, between 0.042 to 0.167 mya. The pattern of Isolation by Distance （IBD） was not significant （r = -0.113, P 〈 0.287）, when all the sampling locations were compared （Mantel test）, however, when an outlier （Indus, Brahmaputra and Mahanadi） was removed from the whole population set, a clear positive correlation between pairwise Fsv and geographic distance （Km） was seen. The analysis of data demonstrated that ATPase6/8 gene polymorphism is a potential marker to understand genetic population structure of wild L. rohita existing in different rivers. The study identified population substructure in wild L. rohita with common ancestral origin [Current Zoology 60 （4）： 460--471, 2014].

关键词： Labeo rohita ATPase6/8 mtDNA Polymorphism Genetic Divergence India

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A Critical Review on Traditional Herbal Drugs: An Emerging Alternative Drug for Diabetes

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International Journal of Organic Chemistry 2013年第1期3卷 1-22页

作者： Krishna Bihari Pandeya Indra Prasad Tripathi Mahendra Kumar Mishra Neelesh Dwivedi Yogesh Pardhi arti Kamal Priyanka gupta Nupa Dwivedi Chinmayi Mishra Faculty of Science & Environment Mahatma Gandhi Chitrakoot Gramoday Vishwavidyalaya Chitrakoot India Reseach Assistant Tropical Forest Research Institute (TFRI) Jabalpur India Research Scholar Mahatma Gandhi Chitrakoot Vishwavidyalaya Chitrakoot India Vice-Chancellor Mahatma Gandhi Chitrakoot Vishwavidyalaya Chitrakoot India

Diabetes is a chronic metabolic disease reaching an epidemic proportion in many parts of the world. By the year 2025 it is expected that 333 million people of the world will have diabetes as their main ailment. As today, India assumes the position of the diabetic capital of the world with the highest percentage of its population suffering from diabetes. It is pathetic to mention that in proportion to its people suffering from diabetes, this country has very weak spending power for treatment because of wide spread poverty. Therefore, this review is aimed at opening up new vistas in realizing the therapeutic potential of Ayurveda in treatment of diabetes and other chronic diseases. All drugs which we have discussed in this review have a significant role in therapy of diabetes mellitus.

关键词： Diabetes Mellitus Metabolic Disease Ayurveda Hyperglycemia Synthetic Drugs Herbal Drugs Metallo Therapy Oral Hypoglycemic Drugs

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