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new perspectives in fish evolution and neurobiology

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Integrative Zoology 2009年第1期4卷 1-2页

作者： Jiakun SOnG arthur n.popper Institute for Marine Biosystem and neurosciences Shanghai Ocean UniversityShanghaiChina Department of Biology University of MarylandCollege ParkMDUSA Division of Fishes National Museum of Natural HistorySmithsonian InstitutionWashingtonDCUSA Center for Comparative and Evolutionary Biology of Hearing University of MarylandCollege ParkMDUSA

ulogy,Chinese Academy of Sciences,Beijing 100080,People’s Republic of Chin The papers presented in this special issue arose from a symposium that took place from 28 november to 1 December 2007 at the Shanghai Ocean University to celebrate the inauguration of the Institute for Marine Biosystem and *** symposium was attended by 158 people,the majority of whom were from leading universities and institutes across China.

关键词： China. fish evolution

Effects of noise on fishes: What we can learn from humans and birds

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Integrative Zoology 2015年第1期10卷 29-37页

作者： Robert J.DOOLInG Marjorie R.LEEK arthur n.popper Department of Psychology University of MarylandCollege ParkMarylandUSA national Center for Rehabilitative Auditory Research PortlandVA Medical CenterPortlandOregonUSA Department of Biology University of MarylandCollege ParkMarylandUSA

In this paper we describe the masking of pure tones in humans and birds by manmade noises and show that similar ideas can be applied when considering the potential effects of noise on fishes,as well as other aquatic *** from many studies on humans and birds,both in the field and in the laboratory,show that published critical ratios can be used to predict the masked thresholds for pure tones when maskers consist of complex manmade and natural *** argue from these data that a single,simple measure,the species critical ratio,can be used to estimate the effect of manmade environmental noises on the perception of communication and other biologically relevant *** also reason that if this principle holds for species as diverse as humans and birds,it probably also applies for all other vertebrates,including fishes.

关键词： behavior communication manmade noise masking sound

The sensory world of fish and fisheries: Impact of human activities–An international conference to evaluate the effects of environmental changes on the sensory world of fish/aquatic animals and fisheries

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Integrative Zoology 2015年第1期10卷 1-3页

作者： Jiakun SOnG Shaun P.COLLIn arthur n.popper Institute for Marine Biosystem and neuroscience College of Life Sciencesand International Center for Marine Studies Shanghai Ocean UniversityShanghaiChina School of Animal Biology and the Oceans Institute The University of Western Australia CrawleyWAAustralia Department of Biology University of Maryland College ParkMDUSA

This special issue of Integrative Zoology(the official journal of the International Society of Zoological Sciences and the Institute of Zoology,Chinese Academy of Sciences)is dedicated to the sensory world of fish and fisheries and the impacts of human *** papers in this issue are the outcome of an international conference that was held at the Institute for Marine Biosystem and neurosciences,College of Fisheries and Life Science,Shanghai Ocean University,Shanghai,China from 29 October to 1 november *** conference was generously sponsored by The Shanghai Ocean University,The University of Maryland and The University of Western Australia.

关键词： fish Impact journal

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《人工听觉-新视野》

声学学报 2016年第1期41卷 143-144页

作者：曾凡钢 [美]arthur n.popper [美]Richard R.Fay 平利川(译) 沈翌(译) 孟庆林(译) 王宁远(译) 王帅(译) 冯海泓(校审) 陈友元(校审) 不详深圳大学信息工程学院

听觉让我们可以进行言语交流、音乐欣赏、感受环境等声音感知活动。在正常的听觉通路中，声音的机械振动主要通过耳廓、耳道、鼓膜和听骨链的传导进入耳蜗，振动信号在耳蜗中被转换为神经电信号，电信号被听觉神经系统逐渐上传至中枢，... 详细信息

听觉让我们可以进行言语交流、音乐欣赏、感受环境等声音感知活动。在正常的听觉通路中，声音的机械振动主要通过耳廓、耳道、鼓膜和听骨链的传导进入耳蜗，振动信号在耳蜗中被转换为神经电信号，电信号被听觉神经系统逐渐上传至中枢，经处理形成听觉。

关键词：听觉通路视野人工神经系统音乐欣赏机械振动振动信号电信号

Manipulation of the immune system by non-small cell lung cancer and possible therapeutic interference

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Cancer Drug Resistance 2020年第4期3卷 710-725页

作者： Helmut H.popper Medical University of Graz Research Unit Molecular Lung&Pleura PathologyInstitute of PathologyNeue Stiftingtalstrasse 6AGraz 8036Austria

Pulmonary carcinomas have developed mechanisms by which they escape the attack of immune *** checkpoint molecules programmed death 1-programmed death ligand 1(PD1-PDL1)and the cytotoxic T-lymphocyte antigen 4 system have gained *** expression of PDL1 by tumor cells causes immune tolerance,and further influences the microenvironment via orchestration by *** with PDL1 antibodies could restore the cytotoxicity of T-lymphocytes towards tumor *** patients will respond to this ***,resistance mechanisms will counteract this *** investigations have identified additional immune checkpoint inhibitors such as lymphocyte activation gene 3 and T cell immunoglobulin and mucin-domain *** cells also induce tolerance by manipulating cells of the innate immune *** are polarized to tumor-friendly M2,neutrophils into n2 types,and dendritic cells and myeloid suppressor cells are switched to assist tumor *** T cells enter the tumor microenvironment and signal tolerance to cytotoxic cells,inhibiting the influx of nK *** mediators either released by tumor cells or cells of the tumor stroma induce immune tolerance,examples including tryptophan and indolamine dioxygenases,arginine and *** options to counteract these molecules are currently being *** tumor stroma has been classified as immune-inflamed,immune-excluded,and immune-desert *** latter might be switched to an inflamed type by induction of tertiary lymph *** cells and macrophages normally phagocytose tumor antigens,but inhibitors of phagocytosis can block *** with these molecules is another option for re-establishing the cytotoxic action of the immune system against tumor *** this review we will discuss these aspects with a special emphasis on non-small cell lung cancer.

关键词： Programmed death 1-programmed death ligand 1 lymphocyte subpopulation innate immune cells soluble mediators of immune tolerance phagocytosis inhibitors

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鲡鱼对声及振动的反应特性(英文)

青岛海洋大学学报（自然科学版） 1989年第3期19卷 52-63页

作者：申钧 Sheryl Coombs R.R.Fay A.n.popper W.M.Saidel 青岛海洋大学海洋生物系洛依勒大学帕姆莱听觉研究所乔治城大学医学院解剖学系

本文用神经生理学和心理物理学技术,在同一声学及振动刺激条件下,在不同水平上对非骨鳔类鲡鱼(Hemichromis bimaculatus)的听觉机能进行了系统研究。结果表明鲡鱼的听觉范围在100～600Hz,敏感频率段为200～300Hz,与骨鳔类有显著差别。... 详细信息

本文用神经生理学和心理物理学技术,在同一声学及振动刺激条件下,在不同水平上对非骨鳔类鲡鱼(Hemichromis bimaculatus)的听觉机能进行了系统研究。结果表明鲡鱼的听觉范围在100～600Hz,敏感频率段为200～300Hz,与骨鳔类有显著差别。以内耳球状中微音器电位和中脑诱发电位测量为依据做出的等电位听力图与整体行为反应听力图的带宽相符。加速度听力图中,在400Hz以上敏感度下降。由声及振动引起的中脑诱发电位听力图相似,一般特征为在100Hz以上出现低通滚降10dB/octave。所有结果都表明鲡鱼对水中声压及质点运动成分均有明显反应,300Hz以下敏感度最高。

关键词：鲡鱼声振动心理物理学

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科学知识进化论

科学知识进化论

1987年

作者：波普尔(popper K.R.)

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科学发现的逻辑

科学发现的逻辑

Recurrent giant hemangiomas of liver:Report of two rare cases with literature review

作者： K.R.·波珀(K.R. popper)

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World Journal of Gastrointestinal Surgery 2012年第11期4卷 262-266页

作者： Hongfa Zhu Khaled Obeidat Jie Ouyang Sasan Roayaie Myron E Schwartz Swan n Thung The Lillian and Henry M Stratton-Hans popper Department of Pathology Mount Sinai Medical CenterNew YorkNY 10029United States Division of Surgical Oncology Department of SurgeryThe Mount Sinai Medical CenterNew YorkNY 10029United States

Most hepatic hemangiomas(HHs) are small,asymptomatic and do not require clinical *** resection is only indicated for symptomatic *** report here cases of recurrent HHs in 2 women of 37 and 40 years old,who initially presented with abdominal pain and *** examination of each tumor revealed a solitary tumor of 14 and 20 cm in diameter,*** liver segmental resections were performed in both,and the diagnosis of cavernous hemangioma was *** patients had recurrent tumor on subsequent radiological examination 4-5 years after the initial *** the first patient,a 15 cm recurrent hemangioma was resected,but multiple hemangiomas were again detected 8 years later occupying the other hepatic lobe,which was not amendable for *** the second patient,a 16 cm hemangioma was seen on radiogram,and because the lesion was not symptomatic,conservative observation was *** after liver resection of giant hemangioma is extremely *** pathogenesis of tumor progression and recurrence is unknown,as is the management of these patients with recurrent hemangioma,particularly when it is extensive and unresectable.

关键词： Liver Giant hemangioma Recurrent hemangioma