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Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight

International Journal of Ophthalmology(English edition) 2022年第10期15卷 1641-1649页

作者： Brenda Nana Wandji artémise dugauquier Adèle Ehongo Faculty of Medicine UniversitéLibre de BruxellesBrussels 1070Belgium Department of Ophthalmology Erasme HospitalBrussels 1070Belgium

AIM: To assess the association between buried optic disc drusen(BODD) location using spectral-domain optical coherence tomography(SD-OCT) and the location of associated visual field defects(VFD) using the Garway-Heath ***: This monocentric retrospective crosssectional study was led at the authors’ institution. Adult patients diagnosed with BODD who had complete records with a reliable Humphrey? 24-2 visual field, macular, and papillary OCT were enrolled. Fisher’s exact test was used to measure the association between BODD location and VFD distribution according to Garway-Heath’s ***: Totally 20 eyes of 15 patients were included(60% females). The median age(interquartile range) was 63(43)y and the median best corrected visual acuity(BCVA) was-0.08(0.08) log MAR. BODD were mostly located in zones A, E, and F. The minimal rim width(MRW) was globally preserved. The retinal nerve fiber layer(RNFL) was predominantly altered in zones D, E, and F. There was a significant correlation between BODD location and that of RNFL alterations in zones D(P=0.03) and E(P=0.025);Moreover, the presence of BODD in the E zone was significantly related to damaged RNFL in the neighbouring sectors D and F(P=0.012;P=0.02 respectively). Sixty-three percent(12/19) of visual fields were abnormal and there was a significant match(Phi=0.7, P=0.009) between drusen location and VFD only in zone ***: BODD do not only affect young patients and can be more harmful than usually expected, as we found VFD in 63% of cases. There is a correspondence between BODD location, RNFL damage, and VFD distributions. The presence of BODD induces the overestimation of MRW,thereby disrupting its sensitivity as an early indicator of ganglion fibers damage.

关键词： buried optic disc drusen visual field spectral-domain optical coherence tomography Garway-Heath mapping retinal nerve fiber layer

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Peripapillary intrachoroidal cavitation at the crossroads of peripapillary myopic changes

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 2063-2070页

作者： Adele Ehongo Zaki Hasnaoui Nacima Kisma Yassir Alaoui Mhammedi artemise dugauquier Kevin Coppens Eloise Wellens Viviane de Maertelaere Francoise Bremer Karelle Leroy Hopital Erasme Bruxelles 1070Belgium Cosma Consulting Sijsjesdreef 13 Enghien 7850Belgium UniversitéLibre de Bruxelles Bruxelles 1070Belgium Biostatistics IRIBHM UniversitéLibre de BruxellesBruxelles 1070Belgium Laboratory of Histology UniversitéLibre de BruxellesBruxelles 1070Belgium

AIM:To analyze the prevalence of peripapillary intrachoroidal cavitation(PICC)in eyes with gamma peripapillary atrophy(γPPA),in eyes with peripapillary staphyloma(PPS)and in those combiningγPPA and PPS and to analyze border tissue discontinuity in ***:This prospective cross-sectional non interventional study included highly myopic ***-highly myopic eyes were used as *** and linear scans centered on the optic nerve head were performed using spectral-domain optical coherence *** were analyzed along the twelve hourly optical coherence tomography sections in both eyes of each ***:A total of 667 eyes of 334 subjects were included:229(34.3%)highly myopic eyes and 438(65.7%)non highly myopic *** mean age of the highly myopic group was 48.99±*** was found in a total of 40 eyes and in 13.2%(29/220)of highly myopic *** was found in 10.4%(40/386)of eyes withγPPA,in 20.5%(40/195)of eyes with PPS and in 22.7%(40/176)of those combiningγPPA and *** the eyes with PICC showed the co-existence ofγPPA and PPS whereas none of the eyes presenting only one of these entities exhibited PICC.A border tissue discontinuity in theγPPA area was found in all eyes with ***:We confirm the presence of a border tissue discontinuity in theγPPA area of all eyes with *** findings suggest the involvement of mechanical factors in the pathogenesis of PICC which may contribute to PICC-related visual field defects.

关键词： myopia peripapillary intrachoroidal cavitation peripapillary staphyloma gamma peripapillary atrophy border tissue myopic complications

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General shape of the optic nerve head in one high myopic glaucomatous patient before and after trabeculectomy

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International Journal of Ophthalmology(English edition) 2020年第11期13卷 1836-1838页

作者： Adele Ehongo artemise dugauquier Yassir Alaoui Mhammedi Department of Ophthalmology Erasme HospitalBrussels 1070Belgium

Dear Editor,I am Adele Ehongo,Head of the Gilaucoma Clinic at Erasme Hospital,Brussels,*** with artemise dugauquier and Yassir Alaoui,I am writing to you to present the case of one glaucomatous myopic patient with cha... 详细信息

关键词： head shape after

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