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Prevalence of Dyslipidemia among Patients Received at the Biochemistry Unit of the Charles de Gaulle Pediatric University Hospital in Ouagadougou

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Advances in Biological Chemistry 2024年第1期14卷 16-26页

作者： Fabienne Marie Soudre arnaud Kouraogo Alice Kiba Ollo Da Mahutin Benoîte Hounhoui Diema Nadia Karama Seraphine Mano Denis Claude Drabo Augustin Kyetega Raoul Karfo Elie Kabre Jean Sakande Health Sciences Training and Research Unit Joseph Ki-Zerbo University Ouagadougou Burkina Faso Charles de Gaulle Pediatric University Hospital Ouagadougou Burkina Faso Health Sciences Institute Nazi BONI University Bobo Dioulasso Burkina Faso Biochemistry Unit Sourou Sanou University Hospital Bobo Dioulasso Burkina Faso Tengandogo University Hospital Ouagadougou Burkina Faso Faculty of Health Sciences Saint Thomas d’Aquin University Ouagadougou Burkina Faso Yalgado Ouedraogo University Hospital Ouagadougou Burkina Faso National Agency for Environmental Food Labor and Health Product Safety Ouagadougou Burkina Faso

Introduction: Cardiovascular disease represents a major public health burden worldwide. Research and management of risk factors contribute to the prevention of these diseases. The aim of this study was to assess the prevalence of dyslipidemia in the biochemistry unit of the Charles De Gaulle Pediatric University Hospital (CHUP-CDG) in Ouagadougou. Material and Methods: This was a descriptive and analytical cross-sectional study, with retrospective data collection from January 1, 2020 to December 31, 2022. Patients of all ages who performed a lipid panel in the CHUP-CDG biochemistry unit during the study period have been included. Results: A total of 2872 patients have been included. The mean age of the study population was 27.72 ± 19.51 years and the M/F sex ratio was 0.81. Among the patients, 22.84% had at least one dyslipidemia. The prevalences of hypercholesterolemia, hypo-HDL cholesterolemia and hyper-LDL cholesterolemia were 11.57%, 49.19% and 57.50% respectively. Hypertriglyceridemia and mixed hyperlipidemia were present in 9.04% and 2.08% of patients. Hypercholesterolemia was significantly more frequent in the female sex (p = 0.0077);hyper-LDL cholesterolemia (p = 0.0255) and mixed hyperlipidemia (p Conclusion: The relatively high prevalence of dyslipidemia in the study indicates a worrying situation. It would therefore appear essential to extend the search for risk factors nationwide, particularly those that can be modified, in order to reduce morbidity and mortality linked to cardiovascular disease.

关键词： Dyslipidemia Lipid Profile Lipid Abnormalities Prevalence Burkina Faso

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Emphysematous Cystitis: Report of Two Cases and Review of the Literature

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Health 2024年第4期16卷 309-318页

作者： Roland Bertile Banga-Mouss Nestor Ghislain Andzouana Mbamognoua Yanick Dimi Nyanga Armel Melvin Atipo Ondongo Steve Aristid Ondziel-Opara Raïssa Laure Mayanda Ohouanda Nick arnaud Monabeka Evariste Bouenizabila Anani Séverin Wences Odzébé Prosper Alain Bouya Urology Department University Hospital of Brazzaville Brazzaville Republic of the Congo Faculty of Health Sciences Marien Ngouabi University Brazzaville Republic of the Congo Department of Metabolic and Endocrine Diseases University Hospital of Brazzaville Brazzaville Republic of the Congo

Emphysematous cystitis is a rare complication of lower urinary tract infection whose prognosis is conditioned by the delay in treatment. The predisposition of diabetic patients to urinary infections caused by gas-producing bacteria is considered one of the most common factors in the occurrence of emphysematous cystitis. The currently recommended diagnostic test is CT scanning, which has definite value in assessing gas accumulation in the bladder wall and lumen. The authors report the observations of two patients aged 68 and 80 who were treated for emphysematous cystitis complicating diabetes mellitus. The evolution was favorable under treatment with antibiotic therapy, insulin therapy and bladder drainage.

关键词： Emphysematous Cystitis Computed Tomography Lower Urinary Tract Infection Diabetes Mellitus

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Poincaréand Logarithmic Sobolev Inequalities for Nearly Radial Measures

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Acta Mathematica Sinica,English Series 2022年第8期38卷 1377-1398页

作者： Patrick CATTIAUX arnaud GUILLIN Li Ming WU Institut de Mathématiques de Toulouse CNRS UMR 5219UniversitéPaul Sabatier118 Route de NarbonneF-31062 Toulouse Cedex 09 Laboratoire de Mathématiques Blaise Pascal CNRS UMR 6620UniversitéClermont-AuvergneAvenue des LandaisF-63177 Aubiere

Poincaréinequality has been studied by Bobkov for radial measures,but few are known about the logarithmic Sobolev inequality in the radial *** try to fill this gap here using different methods:Bobkov's argument and super-Poincaréinequalities,direct approach via L_(1)-logarithmic Sobolev *** also give various examples where the obtained bounds are quite *** bounds obtained by Lee–Vempala in the log-concave bounded case are refined for radial measures.

关键词： Radial measure log-concave measure Poincaréinequality logarithmic Sobolev inequality super-Poincaréinequality

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Short, Medium, and Long-Term Stroke Mortality in Libreville and Associated Factors

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Neuroscience & Medicine 2024年第1期15卷 39-50页

作者： Grass Aurelle Mambila Matsalou Jennifer Nyangui Mapaga Pupchen M. Gnigone Minka’a Pagbe Michael Chermine Mboumba Mboumba Christian Allognon Mahutondji Aissata Ibrahima Camara Annick A. Nsounda Nelly Diouf Mbourou Michel-arnaud Saphou-Damon Elsa Ayo Bivigou Philomene Kouna Ndouongo Neurology Department University Hospital of Libreville Libreville Gabon Cardiology Department University Hospitalof Libreville Libreville Gabon

Strokes are common around the world and especially in sub-Saharan Africa. They are responsible for severe sequelae and the majority of deaths. In Gabon, no study on stroke mortality has been conducted. Objective: To determine short, medium, long-term mortality and factors associated with long-term stroke mortality. Method: Our study took place in the Neurology Department of the University Hospital Center of Libreville (UHCL). It was a historical cohort study with descriptive and analytical purposes covering the period from June 1 to August 31, 2018 and taking into account hospitalized patients from January 1, 2013 to December 31, 2017. We conducted a comprehensive systematic recruitment of patients with stroke, 18 years old and more, and had been agreed to give information. We included all patients meeting the inclusion criteria. The data was gathered using Epi-Info 7 software. The CHI-2 test was used for the comparison of frequencies and the Student’s test, for comparison of means. Multivariate analysis with logistic regression allowed us to look for factors associated with long-term mortality. A result was statistically significant for a p 0.05 value. Results: At 3 months, 28 patients (18.1%) died, at 6 months thirty-one patients or 20.1% died. At 5 years old, fifty-three patients or 34.4% had died. The factors associated with long-term mortality, if the lost of sight were all alive were tobacco (p = 0.01) and stroke (p = 0.008). If all those who were lost to sight had died, no factor was associated with 5-year mortality. Conclusion: Stroke mortality must not be taken for granted, it can be underestimated because of the large number of lost sight. Measures must be put in place to strengthen post-stroke monitoring. .

关键词： Stroke Mortality Associated Factors Libreville

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Transaction fees optimization in the Ethereum blockchain

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Blockchain(Research and Applications) 2022年第3期3卷 12-22页

作者： arnaud Laurent Luce Brotcorne Bernard Fortz INRIA Lille Nord-Europe 40 Avenue HalleyLille59000France Universitélibre de Bruxelles Bruxelles1050Belgium

In blockchains,transaction fees are fixed by the *** probability for a transaction to be processed quickly increases with the fee *** this paper,we study the transaction fee optimization problem in the Ethereum *** problem consists of determining the minimum price a user should pay so that its transaction is processed with a given probability in a given amount of *** reach this goal,we define a new solution method based on a Monte Carlo approach to predict the probability that a transaction will be mined within a given time *** results on real data highlight the quality of the results.

关键词： Pricing Blockchain Ethereum Optimization Gasprice Ether Monte-Carlo

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Urological Emergencies at the University Hospital of Brazzaville: Epidemiological, Clinical, and Therapeutic Aspects

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Open Journal of Urology 2024年第5期14卷 333-345页

作者： Roland Bertile Banga-Mouss Yannick Dimi Nyanga Irène Ondima Armel Melvin Atipo Ondongo Steve Aristide Ondziel-Opara Joseph Junior Damba Nick arnaud Monabeka Christ Ondzé Daniella Gloire Ngassiele Gidmard Onguele Henock Songa Jetsvy Mayala Anani Wensels Severin Odzebe Prosper Alain Bouya Departement of Urology and Andrology University Hospital of Brazzaville Brazzaville Republic of the Congo

Introduction: Urological emergencies play a significant role in the medical and surgical activity of a urology department. The objective of this study was to determine the hospital prevalence of urological emergencies at the University Hospital of Brazzaville (CHUB), identify the different pathologies requiring urgent care, and list the various therapeutic methods. Patients and methods: A retrospective study of patients admitted to the medical and surgical emergencies department of CHUB over a 5-year period. Patient records admitted and treated for a urological emergency were included. The variables studied were the frequency of urological emergencies, patient age at admission, gender, nature of the emergency, and various therapeutic options. Results: Urological emergencies accounted for 4.3% of all medical and surgical emergencies. The mean age was 57 ± 28 years with a range of 3 to 93 years. The male-to-female ratio was 7.1. The most common conditions were urinary retention (54.67%), hematuria (17.20%), and renal colic (8.13%). Therapeutically, surgical urinary drainage was dominated by cystostomy. Conclusion: Urological emergencies are infrequent at the University Hospital of Brazzaville. Their management is often delayed.

关键词： Urological Emergencies Urinary Retention Hematuria Renal Colic

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Steroidogenic Effects and Phytochemical Profile of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels in Male Rats

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Journal of Biosciences and Medicines 2023年第10期11卷 156-167页

作者： Herman Akassa Bonaventure Max Lazare Peneme Constantin Moukouma Dieu-Merci Bevel Gallo mongo Rachie Osandze arnaud Wilfrid Etou Ossibi Ange Antoine Abena Laboratory of Biochemistry and Pharmacology Faculty of Health Sciences Marien Ngouabi University Brazzaville Republic of the Congo Laboratory of Animal Physiology Faculty of Science and Technology Marien Ngouabi University Brazzaville Republic of the Congo Departement of Pharmacopeia and Traditional Medicine National Institute for Research in Health Sciences (IRSSA) Brazzaville Republic of the Congo Chemistry Unit of the Plant and Life Faculty of the Sciences and Techniques Marien Ngouabi University Brazzaville Republic of the Congo Faculty of Applied Sciences Denis Sassou Nguesso University Kintelé Republic of the Congo

The main aim of this study was to evaluate the steroidogenic effects and phytochemical profile of aqueous extract of Tetracarpidium conophorum in male rats. Assays of biochemical reproductive parameters (total cholesterol, serum testosterone, FSH and LH) were carried out using Cypress and ELISA kits respectively. The chemical screening of the extract was conducted through tube reactions, the principle of which involves adding a reagent to a quantity of the extract, and subsequently observing the resulting reactions such as precipitation and color change. The results obtained showed that oral administration of the aqueous extract of Tetracarpidium conophorum (250 and 500 mg/kg) produced a significant increase (p Tetracarpidium conophorum kernels at the doses studied produced a very significant decrease in total cholesterol levels (p Tetracarpidium conophorum kernels could have hypocholesterolemic and steroidogenic potential. A study of the aqueous extract of Tetracarpidium conophorum on semen quality and oxidative stress parameters deserves to be conducted.

关键词： Tetracarpidium conophorum Steroidogenic Chemical Screaming

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Self-supervised image quality assessment for X-ray tomographic images of Li-ion battery

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npj Computational Materials 2022年第1期8卷 1848-1856页

作者： Kai Zhang Tuan-Tu Nguyen Zeliang Su arnaud Demortière Laboratoire de Réactivitéet Chimie des Solides(LRCS) CNRS UMR 7314UPJVHub de l’Energie15 rue Baudelocque80039Amiens CedexFrance ENSTA Paris 91120PalaiseauFrance Renault Technocentre 78084GuyancourtFrance Réseau sur le Stockage Electrochimique de l’Energie(RS2E) CNRS FR 3459Hub de l’EnergieRue Baudelocque80039Amiens CedexFrance ALISTORE-European Research Institute CNRS FR 3104Hub de l’EnergieRue Baudelocque80039Amiens CedexFrance

Image perception plays a fundamental role in the tomography-based approaches for microstructure characterization and has a deep impact on all subsequent stages of image processing,such as segmentation and 3D *** enhancement of image perception,however,frequently involves observer-dependence,which reflects user-to-user dispersion and uncertainties in the calculated *** work presents an objective quantitative method,which uses convolutional neural networks (CNN) for the quality assessment of the X-ray tomographic *** only dozens of annotations,our method allows to evaluate directly and precisely the quality of tomographic *** metrics were employed to evaluate the correlation between our predicted scores and subjective human *** evaluation results demonstrate that our method can be a direct tool to guide the enhancement process in order to produce reliable segmentation *** processing of the tomographic image can thus evolve into a robust observer-independent procedure and advance towards the development of an efficient self-supervised approach.

关键词： image networks battery

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Effects of C2 hemisection on respiratory and cardiovascular functions in rats

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Neural Regeneration Research 2023年第2期18卷 428-433页

作者： Pauline Michel-Flutot arnaud Mansart Abdallah Fayssoil Stéphane Vinit UniversitéParis-Saclay UVSQInsermEND-ICAPVersaillesFrance UniversitéParis-Saclay UVSQInsermInfection et Inflammation(2I)VersaillesFrance Raymond PoincaréHospital AP-HPGarchesFrance

High ce rvical spinal co rd injuries induce permanent neuromotor and autonomic *** injuries impact both central respiratory and cardiovascular functions through modulation of the sympathetic nervous *** far,cardiovascular studies have focused on models of complete contusion or transection at the lower cervical and thoracic levels and diaphragm activity evaluations using invasive *** present study aimed to evaluate the impact of C2 hemisection on different parameters representing vital functions(i.e.,respiratory function,cardiovascular,and renal filtration parameters)at the moment of injury and 7 days post-injury in *** ventilatory parameters evaluated by plethys mography were impacted during quiet breathing after 7 days post-injury,whereas permanent diaphragm hemiplegia was observed by ultrasound and confirmed by diaphragmatic electromyography in anesthetized ***,the mean arterial pressure was reduced immediately after C2 hemisection,with complete compensation at 7 days *** filtration was unaffected at 7 days post-injury;however,remnant systolic dysfunction chara cterized by a reduced left ventricular ejection fraction persisted at 7 days *** together,these results demonstrated that following C2 hemisection,diaphragm activity and systolic function are impa cted up to 7 days post-injury,whereas the respiratory and cardiovascular systems display vast ada ptation to maintain ventilatory parameters and blood pressure homeostasis,with the latter likely sustained by the remaining descending sympathetic inputs spared by the initial injury.A better broad characterization of the physiopathology of high cervical spinal cord injuries covering a longer time period post-injury could be beneficial for understanding evaluations of putative therapeutics to further increase cardiorespiratory recovery.

关键词： C2 spinal cord injury cardiovascular diaphragm activity heart function hemiplegia rat model respiratory ultrasound

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Feedback of inter-hospital transfer of patients under high-flow nasal cannula oxygen therapy

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World Journal of Emergency Medicine 2022年第3期13卷 219-221页

作者： Emilien arnaud Sylvain Leclere Martin Petitprez Gilles Vincent Christine Ammirati Department of Emergency Medicine Amiens-Picardy University HospitalAmiens 80000France

Severe forms of coronavirus disease 2019 (COVID-19)can lead to hypoxemic pneumonia and the need for treatment with high-flow nasal cannula (HFNC) oxygen *** treatment decreases the need for subsequent invasive ventilation in patients with hypoxemic *** oxygen flow in the nasal cannula is driven pneumatically or using a *** and air are mixed (giving the fraction of inspired oxygen[FiO;]) and propelled at up to 80L·min;.The propelled gases must be heated and *** system is not intended for use outside a hospital environment.

关键词： nasal patients flow

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