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Public-private-partnership needs under the National Tuberculosis Elimination Program in an Eastern Indian state

Asian Pacific Journal of Tropical Medicine 2024年第10期17卷 432-434页

作者： Janmejaya Samal arnab mondal School of Public Health SRM Institute of Science and TechnologyKattankulathurTamilnaduIndia Independent Public health Researcher BhubaneswarOdishaIndia

Eliminating tuberculosis(TB)is among India's top public health priorities[1].Despite the considerable progress in providing quality TB care services,the Global TB report-2022 reveals that India is amongst the eight high TB burden countries that contributed to more than two-thirds(68.3%)of the global TB cases[2].To strengthen and aid the TB elimination efforts by 2025,five years ahead of the sustainable development goal target,the Government of India,under the program,promotes intersectoral convergence with various public sector departments and the private *** national multisectoral action framework for TB-free India promotes private-private or public-private partnerships for sustainable and impactful Corporate Social Responsibility initiatives[3].

关键词： partnership Eastern Indian

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Oncometabolites in pancreatic cancer:Strategies and its implications

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World Journal of Experimental Medicine 2024年第4期14卷 23-38页

作者： Arunima Maiti Susmita mondal Sounetra Choudhury arnab Bandopadhyay Sanghamitra Mukherjee Nilabja Sikdar Suraksha Diagnostics Pvt Ltd NewtownRajarhatKolkata 700156West BengalIndia Department of Zoology Diamond Harbour Women’s UniversityDiamond Harbour 743368West BengalIndia Human Genetics Unit Indian Statistical InstituteKolkata 700108West BengalIndia Department of Oncology Command HospitalLucknow 226002India Department of Pathology RG Kar Medical College and HospitalKolkata 700004West BengalIndia Scientist G Estuarine and Coastal Studies FoundationHowrah 711101West BengalIndia

Pancreatic cancer(PanCa)is a catastrophic disease,being third lethal in both the genders around the *** possible reasons are extreme disease invasiveness,highly fibrotic and desmoplastic stroma,dearth of confirmatory diagnostic approaches and resistance to *** inimitable tumor microenvironment(TME)or desmoplasia with excessive extracellular matrix accumulation,create an extremely hypovascular,hypoxic and nutrient-deficient zone inside the *** survive,grow and proliferate in such tough TME,pancreatic tumor and stromal cells transform their *** glucose,glu-tamine,fat,nucleotide metabolism and inter-metabolite communication between tumor and TME in synergism,impart therapy resistance,and immunosuppression in ***,a finer knowledge of altered metabolism would uncover its metabolic *** unique metabolic targets may help to device novel diagnostic/prognostic markers and therapeutic strategies for better management of *** this review,we sum up reshaped metabolic pathways in PanCa to formulate detection and remedial strategies of this devastating disease.

关键词： Metabolic reprogramming Pancreatic cancer Metabolic symbiosis Therapy resistance Anti-pancreatic cancer therapy

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