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Endoscopic Management of Severe Supraglottic and Posterior Glottic Stenosis Due to Chemotherapy and Radiation

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International j.urnal of Otolaryngology and Head & Neck Surgery 2014年第3期3卷 133-136页

作者： Shaina M. Rubino Michael j. Pitman Department of Otolaryngology New York Eye & Ear Infirmary The Voice & Swallowing Institute New York USA New York Medical College Valhalla USA

Combined posterior and supraglottic stenosis (CS) often presents as debilitating dysphonia or dyspnea, secondary to blunt trauma or traumatic intubation. However, CS has proven to be a late complication of chemoradiation therapy. Traditional treatment of combined posterior and supraglottic stenosis (CS) secondary to chemoradiation has been frequently complicated by poor tissue healing. This case study illustrates a novel endoscopic surgical technique employing a large laterally-based flap as a posterior glottic keel by rotating it anteroinferiorly and suturing it in place. As a result of the procedure, the bilateral vocal folds, which were midline and immobile preoperatively, regained normal motion. The supraglottic airway was also restored. Successful endoscopic treatment of CS with bilateral vocal fold immobility is possible using a large laterally-based flap, even in the face of tissue changes secondary to chemoradiation.

关键词： Posterior Glottic Stenosis Supraglottic Stenosis Combined Glottic Stenosis Radiation Endoscopic Surgery

A Comparative Study on the Utilization of Corn Pericarp and Peanut Hull in the Production of Ethanol and the Impact on Food Economics

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Food and Nutrition Sciences 2016年第11期7卷 1010-1020页

作者： j. L. Herring V. C. Narayanan Department of Food & Animal Sciences Alabama A&M University Normal AL USA

Corn pericarp and peanut hull (lignocellulosic materials) which are food industry by-products were used as substrates in this study. Alkaline hydrogen peroxide (H2O2) pretreatments at 0%, 2.5% and 5% were used for the removal of lignin. Simultaneous Saccharification and Fermentation (SSF) and Separate Hydrolysis and Fermentation (SHF) were conducted using Aspergillus niger (strain 201201) and Saccharomyces cerevisiae (strain 26603). Aspergillus niger was added on day 1 to all samples with inoculation treatments of S. cerevisiae at one-day intervals (A = Day 1, B = Day 2, C = Day 3 and D = Day 4). Pretreatment with 2.5% H2O2 was more beneficial in the removal of lignin for both substrates. Corn pericarp yielded an ethanol concentration of 22.2 g/L in C and 21.78 g/L in D of 2.5% H2O2 pretreatment. Peanut hull with 2.5% H2O2 pretreatment in D yielded a higher concentration at 10.38 g/L compared to other inoculation treatments. The highest ethanol yielded on a percentage basis for corn pericarp was 45.04% in C of 2.5% H2O2 pretreatment and 24.6% in D of 2.5% H2O2 pretreatment for peanut hull.

关键词： Ethanol Peanut Hull Corn Pericarp Alkaline Pretreatment Fermentation

[1-(4-Nitrobenzyl)-2-butyl-4-chloro-1<i>H</i>-imidazol-5-yl]-4, 5-dihydro-1-phenyl-1<i>H</i>-pyrazole: Synthesis, Anti-Inflammatory and Analgesic Activities

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Open j.urnal of Medicinal Chemistry 2013年第2期3卷 50-54页

作者： S. Sreenivasa B. j. Shankar Department of Studies and Research in Chemistry Tumkur University Tumkur India

In the present investigation, series of Bis (heterocycle)s bearing pyrazoline in combination of the imidazole derivatives have been synthesized via 1,3-dipolar cycloaddition reactions of N-(nitrobenzyl)-imidazole nitrile imines with different dipolarophiles. All the newly synthesized compounds were characterized and screened for analgesic-anti-inflammatory activities and were compared with the standard drugs. The compounds exhibited excellent anti-inflammatory and analgesic activities. Out of the compounds studied 4b, 4d and 4g compounds shown statistically significant activity comparable to the standard drugs Ibuprofen and Aspirin at the same dose.

关键词： Anti-Inflammatory Analgesic N-(nitrobenzyl)-imidazole aldehyde Chloramine-T

Milk Quality in Dual Purpose Cattle with Hand or Machine Milking

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j.urnal of Agricultural Science and Technology(A) 2011年第8期1卷 1269-1274页

作者： C. Luna-Palomera K. S. Aguilar-Hemandez j. R. Velitzquez-martinez j. A. Peralta-Torres j.A.Aguilar-Cabrales Division Acaddmica de Ciencias Agropecuarias Universidad Juarez Autonoma de Tabasco Av. Universidad S/N Zona de laCultura Col. Magisterial C.P. 86040 Villahermosa Tabasco Mexico

To evaluate and improve the milk quality in dual purpose cattle with hand or machine milking, a good management and sanitary program was implemented （GMSP） in 40 farms. Was obtained a diagnostic by an interview and in situ evaluation of management conditions and milk samples for laboratory analysis integrating the platform and microbiological counts, before and after of GMSP. The changes achieved were no significant （P 〉 0.05） for pH and density, but alcohol and foreign material were positive modified （P 〈 0.05） by GMSP in both hand and machine milking. The quantities of sediments were decreased （P 〈 0.05） in more than 50.0%. Decrease （P 〈 0.05） was observed in the counts of CFU mL1 （colony forming unitsl） in aerobic mesophilic, coliforms, Salmonella ssp. and Staphylococcus aureus with the GMSP. After GMSP Salmonella ssp. incidence was affected （P 〈 0.05） by hand （55.5%） vs. machine （61.5%） milking type; coliforms count and positive incidence in milk were affected （P 〈 0.05） in hand （81.5%） vs. machine （53.9%）. Therefore it was confirmed that the implementation of adequate sanitary and management practices, in both hand and machine milking, decreased the presence and incidence of microorganisms in milk with potential to produce disease in animals and humans.

关键词： Good livestock management practices livestock tropical systems food safety

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演说的艺术

THE STORY OF BIRTH OF GOETHERT'S RULE As told to the B H Goethert Professor

2014年

作者： (美)戴尔·卡内基(Dale Carnegie) (美)j.伯格·埃森文(j. Berg Esenwein)

本书以独特的视角，探讨看似简单却蕴藏深刻道理的为人处世准则。比如：“培养当众说话的勇气和信心”、“使对方一开始就说'是'”、“激发对方高尚的动机”等。

ISBN: (数字)9787205079635

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来源：汇雅图书（南通市图书馆... 评论

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北京航空航天大学学报 1988年第2期 158-159页

作者： Dr. j. M. Wu of UTSI

In solving for two different Mach number flows over a body, if one can stretch the body and space in such a way that the governing, small disturbance, inviscid partial differential equation of motion(including coefficients) is exactly the same, and with the same applied geometrical boundary conditions(thus restricted to affine bodies), then the solut-

关键词： As over THE STORY OF BIRTH OF GOETHERT’S RULE As told to the B H Goethert Professor body

PET/CT and Hypo-Fractionated Radiotherapy of Patients with Head and Neck Cancer

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International j.urnal of Clinical Medicine 2018年第10期9卷 751-759页

作者： Misleidy Nápoles Morales Aldo martínez Ramirez j.an P. Oliva Glez Claudia González Espinosa j.aquín González González Carlos Fabián Calderón Marín Waldo Quesada Cepero Fanny López Reina Rubén Elzaurdín Mora Department of Radiotherapy Institute of Oncology and Radiobiology Havana Cuba Nuclear Medicine Department and Molecular Imaging Institute of Oncology and Radiobiology Havana Cuba Radiotherapy Department Medical Researchers Center Havana Cuba

Positron emission tomography/Computer tomography (PET/CT) is a multimodality imaging diagnostic technique that analyzes the uptake and retention of different radiopharmaceuticals by cells providing metabolic information on biochemical processes. PET/CT has been used for radiotherapy planning, providing useful information to the Radio-oncologist about the localization, size and metabolic activity of tumor lesions. In this paper, we show advantages of the 18F-FDG PET/CT respect to simple CT imaging for target volume delineation in patients with diagnosis of Squamous Head and Neck Carcinoma that has been scheduled to undergo a hypofractionated radiotherapy treatment. On ten studied patients, the target volume defined from PET/CT images was less extensive than those defined from simple CT images. In six patients the target volume was significantly less extensive and in two of them a new lymph node disease was reported, re-staging and corresponding target volume was also delineated with less extensive margins from PET/CT images. A greater accuracy in delineating the volumes and improving the distribution of doses in the planning of the radiant treatment in these patients was possible, allowing a high precision in the delivery of the prescribed dose to the target volume diminishing the maximum dose to the adj.cent healthy tissues. In conclusion we show that the use of 18F-FDG PET/CT was superior than the simple CT as the primary modality of imaging for hypofractioned radiotherapy treatment planning in patients with Squamous Head and Neck Carcinoma.

关键词： PET-CT Hypofractionated Radiotherapy Head and Neck Cancer

Quinine induced thrombotic microangiopathy and thrombocytopenia: A teaching hospital’s perspective

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Advances in Generial Practice of Medicine 2019年第1期2卷 9-12页

作者： Aaron j. Franke William Paul Skelton IV Department of Medicine University of Florida College of Medicine Gainesville Florida 32608 USA Moffitt Cancer Center University of South Florida College of Medicine Tampa Florida 33612 USA

Although quinine is an infrequently prescribed drug, with malaria treatment being its only FDA-approved indication, unwitting exposure via beverages (e.g., tonic water), over the counter herbal remedies and illegal recreation drugs still occur. We present a unique case of a female patient who denied any known prior history of quinine exposure, who after being prescribed quinine tablets for restless leg syndrome, developed an immune-related thrombotic microangiopathy with thrombocytopenia and subsequent multi-organ failure. It was later elucidated that her only known potential source of prior quinine exposure was a remote history of crackcocaine use. The patient survived this rare and severe inflammatory response with recovery of renal function and was able to discontinue dialysis.

关键词： Quinine TMA drug reaction DITMA thrombocytopenia

Evaluating Structural and Temporal Factors Affecting Supply of Ecosystem Benefits in a University Urban Environment in South Carolina, USA

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Open j.urnal of Forestry 2022年第3期12卷 297-311页

作者： Puskar N. Khanal Raj.n Paraj.li Thomas j. Straka Department of Forestry & Environmental Conservation Clemson University Clemson SC USA Department of Forestry & Environmental Resources North Carolina State University Raleigh NC USA

Sustainable urban forest management is still an evolving concept, particularly as it pertains to a sustainable supply of ecosystem benefits and management planning. Urban forestry maintains a greater human dimension component than traditional timber-oriented rural forestry because urban trees grow in city centers and neighborhoods, supplying critical ecosystem benefits to the population centers. The overall goal of this study was to evaluate the relationship of urban forest stand structure and its temporal dynamics with the sustainable supply of ecosystem benefits in university environments. Individual tree data were collected from a completed inventory, while the i-Tree Eco model was used to generate ecosystem benefits data from the Clemson urban forest. The cumulative-benefits supply curve had an inverted j.shaped curve, but the average supply curve had a negative slope against the species richness. Likewise, individual tree variables total height, DBH, leaf area, and crown height strongly correlated with the total ecosystem services supply. Based on the temporal supply trends, the study area trees were broadly segmented into three groups: establishment, growth, and legacy, with 65%, 31%, and 4% frequency distribution, respectively. Urban forest managers need to identify forest management goals and preferred ecosystem benefits among the urban communities to guide the required forest structure and dynamics to ensure a sustainable and functioning urban forest.

关键词： Sustainability Urban Forest Structure Ecosystem Services i-Tree Economic Benefits