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Occult hepatitis C virus infection is more common than hepatitis B infection in maintenance hemodialysis patients

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World Journal of Gastroenterology 2008年第14期14卷 2288-2289页

作者： Pankaj jain Sandeep Nijhawan Department of Gastroenterology SMS Medical College Jaipur 302004 India

Patients of end stage renal disease on maintenance hemodialysis were enrolled to study the prevalence of occult and dual hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and non-occult hepatitis B and C virus infection. One hundred and two patients were enrolled. Thirty patients had HCV infection, three of them were positive in anti-HCV. So, 27 (90%) of HCV-positive patients had occult HCV infection. Eleven (11%) patients had HBV infection. Five patients were positive in anti-HBc or HBV-DNA, but negative in HBsAg (occult HBV infection). Three (3%) patients had dual HBV and HCV infection. None of the patients showed changes in viral markers during the follow-up of 8 mo on average (1-12 mo).

关键词： Occult hepatitis C Hepatitis B Maintenance hemodialysis

The effect of side walls on particles mixing in rotating drums

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Particuology 2023年第1期72卷 112-121页

作者： Aman jain Fabien Evrard Berend van Wachem Chair of Mechanical Process Engineering Otto-von-Guericke-University MagdeburgUniversitaetsplatz 2Magdeburg 39106Germany

In this paper, we study the effects of the presence and shape of side walls and of the overall length of rotating cylindrical drums on the mixing of particles with differing sizes by application of the discrete element method (DEM). By varying the semi-axis of the spheroidally shaped side walls and the length of the overall drum, we observe the formation of circulation patterns near the side walls. Although there is a vast amount of literature studying mixing regimes in rotating drums, little is known about the effect of the side walls of the drum on particle mixing. The results of our study demonstrate that introducing curved side walls induces a strong circulation pattern near these side walls, but has, paradoxically, a negative impact on mixing and actually promotes segregation. The cause for this segregation is the difference in velocity of differently sized particles near the curved side walls. Large particles accumulate at the curved side walls, whereas small particles move away from the curved side walls. When the length of the drum is increased, the overall effect of the side walls is decreased, although it does remain observable, even in very large drums.

关键词： Discrete element method Rotating drums Particle mixing Side walls of rotating drums

Parameters influencing the optical properties of SnS thin films

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Journal of Semiconductors 2013年第9期34卷 26-31页

作者： Priyal jain P.Arun Department of Electronic Science University of Delhi-South CampusBenito Juarez MargDelhi 110021India Material Science Research Lab S.G.T.B.Khalsa College University of DelhiDelhi 110007 India

Tin sulphide （SnS） thin films have been recognized as a potential candidate for solar cells. Many fab- rication techniques have been used to grow SnS thin films. The band-gap, Eg of SnS films as reported in litera ture, were found to vary from 1.2-2.5 eV depending on the film fabrication technique. The present work reports the structural, compositional, morphological and optical characterization of SnS thin films fabricated by thermal evaporation at room temperature. Results show that for the given fabrication technique/condition, the band-gap functionally depends on the lattice parameter and grain size. The well-defined variation allows for tailoring SnS film as per requirements.

关键词： nano-composites nanostructures photoluminescence oxides

Full-Duplex Cooperative Relaying with Non-Linear Energy Harvesting for Vehicular Communication

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Journal of Communications and Information Networks 2023年第4期8卷 369-377页

作者： Vaijayanti Panse Tapan Kumar jain Indian Institute of Information Technology Nagpur441108India

This paper analyses the performance of fullduplex(FD)dual-hop vehicular cooperative network with decode-and-forward(DF)*** FD relay nodes,we examine the effects of non-linear hybrid power time splitting(PTS)based energy harvesting(EH).All three nodes—source(S),relay(R),and destination(D)are assumed to be moving *** expressions for the system's outage probability(OP)over double(cascaded)Rayleigh fading channels are *** also analyse the impact of residual self-interference(RSI)caused at FD relay on system's *** compare the performance of system with two relay selection techniques,namely,maximum channel gain-based(Max-G)relay selection and minimum RSI-based(Min-SI)relay *** paper considers the joint effect of time splitting ratio and self-interference cancellation(SIC)level to find the optimum EH ***,the effect of time splitting ratio and average signal-to-noise ratio(SNR)on outage and throughput performance of the system are also investigated in this *** derived expressions are validated through Monte Carlo simulations.

关键词： Cooperative communication vehicular networks energy harvesting full-duplex outage probability

Inhibition and attenuation of pathogenicity of Porphyromonas gingivalis by leupeptin： A review

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Frontiers in Biology 2017年第3期12卷 192-198页

作者： Hansa jain Harsarn Dass Dental College India

BACKGROUND： Porphyromonas gingivalis is a periodontal pathogen, which is considered to be a keystone pathogen for periodontitis. A diverse conglomerate of P. gingivalis virulence factors including lipopolysaccharide, fimbriae, capsular polysaccharide, haemagglutinin and cysteine proteases （Arg-gingipains and Lys-gingipain） are considered to be involved in the pathogenesis ofperiodontitis. Leupeptin is a cysteine protease inhibitor which is specific for Arg gingipains. The present review focuses on action of leupeptin on Arg gingipains. METHOD： A search was carried out systematically from the start till September, 2016. The search was made in Medline database via PubMed. The keywords enlisted were ＂leupeptin＂; ＂gingipains＂; ＂periodontitis＂ using Boolean operator ＂and.＂ RESULTS： The result was selection of 58 articles which linked leupeptin to periodontitis and gingipains; pathogenesis of periodontitis, pathogenicity of gingipains and role of leupeptin. CONCLUSION： It was concluded that leupeptin inhibits and attenuates a number of destructive activities of Arg gingipains including inhibition ofplatelet aggregation; inhibit degradation of LL-37, which is an antimicrobial peptide; blocking inhibition ofmonocyte chemoattractant protein; restoring level ofinterleukin-2; inhibiting degradation of collagen type I and IV to name a few.

关键词： Porphyromonas gingivalis gingipains leupeptin cysteine protease inhibitor periodontitis

Nanodiamonds with powerful ability for drug delivery and biomedical applications:Recent updates on in vivo study and patents

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Journal of Pharmaceutical Analysis 2020年第1期10卷 1-12页

作者： Swati Chauhan Neha jain Upendra Nagaich Department of Pharmaceutics Amity Institute of PharmacyAmity UniversityNoidaU.P.India

Nanodiamonds are novel nanosized carbon building blocks possessing varied fascinating mechanical,chemical,optical and biological properties,making them significant active moiety carriers for biomedical *** are known as the most‘captivating’crystals attributed to their chemical inertness and unique properties posing them useful for variety of applications in biomedical ***,it becomes increasingly important to find,ascertain and circumvent the negative aspects associated with *** modification or functionalization with biological molecules plays a significant role in managing the toxic behavior since nanodiamonds have tailorable surface *** take advantage of nanodiamond potential in drug delivery,focus has to be laid on its purity,surface chemistry and other considerations which may directly or indirectly affect drug adsorption on nanodiamond and drug release in biological *** review emphasizes on the basic properties,synthesis techniques,surface modification techniques,toxicity issues and biomedical applications of *** the development of nanodiamonds as an effective dosage form,researchers are still engaged in the in-depth study of nanodiamonds and their effect on life interfaces.

关键词： Nanomedicine Biochemical application Diamondoids Surface functionalization Drug targeting

Cationic antimicrobial peptide： LL-37 and its role in periodontitis

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Frontiers in Biology 2017年第2期12卷 116-123页

作者： Hansa jain Department of Pedodontics Harsarn Dass Dental College India

BACKGROUND： Periodomitis i.e. inflammation of the periodontium is a multifactorial disease. Antimicrobial peptides （AMPs） which demonstrate a broad-spectrum of activity against varied number of bacteria, fungi, viruses, and parasites, and cancerous cells have been linked to periodontitis. The AMPs even possess the caliber of immunomodulation, and are significantly responsive to innate immuno-stimulation and infections. LL-37 plays a salubrious role by preventing and in treatment of chronic forms of periodontitis. OBJECTIVE： In the present work we will review the role of antimicrobial peptide LL-37 in periodontitis. METHODS： A systematic search was carried out from the beginning till August, 2016 using the Pubmed search engine. The keywords included ＂LL-37,＂＂periodontitis,＂＂Papillon-Lefevre syndrome,＂＂Morbus Kostmann,＂＂Haim-Munk syndrome＂ along with use of Boolean operator ＂and.＂ RESULTS： The search resulted in identifying 67 articles which included articles linking LL-37 with periodontitis, articles on Papillon-Lefevre syndrome, Morbus Kostmann, Haim-Munk syndrome, LL-37 and periodontitis and articles on pathogenicity of periodontitis. CONCLUSION： The literature search concluded that LL-37 plays a pivotal role in preventing and treatment of severe form of periodontitis.

关键词： LL-37 antimicrobial peptides cathelicidin periodontitis

Bianchi Type-IX String Cosmological Models for Perfect Fluid Distribution in General Relativity

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Chinese Physics Letters 2010年第7期27卷 299-301页

作者： Atul Tyagi Keerti Sharma Payal jain Department of Mathematics and Statistics College of Science MLS University Udaipur-313001 India Department of Mathematics Techno India NJR Institute of Technology Udaipur-313004 India

The present study deals with Bianchi type-IX string cosmological models for perfect fluid distribution. We consider two cases：（i） ρ ＋ λ = 0, （ii） ρ - λ = 0, where ρ and λ are the rest energy density and the tension density of a string cloud, respectively. The physical and geometrical properties of the models are discussed.

关键词： Models Dormancy Density

Neutrino spin-flavor oscillations in solar environment

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Research in Astronomy and Astrophysics 2020年第8期20卷 201-210页

作者： Sandeep Joshi Sudhir R.jain Nuclear Physics Division Bhabha Atomic Research CentreMumbai 400085India Homi Bhabha National Institute Anushakti NagarMumbai 400094India

We study the phenomenon of neutrino spin-flavor oscillations due to solar magnetic *** allows us to examine how significantly the electron neutrinos produced in the solar interior undergo a resonant spin-flavor *** construct analytical models for the solar magnetic field in all the three regions of the *** spin-flavor oscillations in this magnetic field are examined by studying the level crossing phenomenon and comparing the two cases of zero and non-zero vacuum mixing *** from the Borexino experiment are used to place an upper limit on the magnetic field in the solar *** phenomena such as effects of matter on neutrino spin transitions and differences between Dirac and Majorana transitions in the solar magnetic fields are also discussed.

关键词： neutrinos:neutrino spin-flavor oscillations Sun:magnetic fields