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Modified deep sclerectomy combined with Ex-PRESS filtration device versus trabeculectomy for primary open angle glaucoma

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International Journal of Ophthalmology(English edition) 2017年第5期10卷 728-732页

作者： Vassilios Kozobolis Georgios D.Panos aristeidis konstantinidis Miguel Teus Georgios Labiris Department of Ophthalmology University General Hospital of Alexandroupolis School of Medicine Democritus University of Thrace Alexandroupolis Eastem Macedonia and ThraceGR-68100 Greece Eye Institute of Thrace School of Medicine Democritus University of Thrace Alexandroupolis Eastern Macedonia and Thrace GR-68100 Greece Glaucoma Laser Eye Center Athens GR-10674 Greece Department of Ophthalmology School of MedicineUniversity of Alcala Madrid ES-28801 Spain

AIM：To compare the efficacy of modified deep sclerectomy combined with Ex-PRESS shunt versus trabeculectomy in primary open angle glaucoma. METHODS：This is a prospective cohort comparative single-center study. Forty-nine eyes of 49 patients were enrolled in the study. Patients were randomly divided into two groups. Group A（22 patients） underwent classic trabeculectomy and group B（27 patients） underwent modified deep sclerectomy combined with insertion of Ex-PRESS model P50 drainage device. RESULTS：Mean age was 69±7y in group A and 64±8y in group B（P=0.03）. The mean reduction was 11.1±5.7 mm Hg in group A compared to 15.8±5.7 mm Hg in group B at 6mo（P=0.006）, and 9.8±4.9 mm Hg and 15.4±4.7 mm Hg respectively at 1y（P=0.0001）. Regarding the postoperative glaucoma medication, significant difference was observed between the two groups（in favour of group B） only at 6mo（P=0.017）. At the end of the follow-up period complete success rate in group A was 68.2% compared to 92.6% in group B（χ^2 test, P=0.07） and qualified success rate was 100% in both ***：Modified deep sclerectomy combined with Ex-PRESS shunt may provide comparable IOP reduction with fewer complications in management of primary open angle glaucoma.

关键词： modified deep sclerectomy Ex-PRESSdrainage device trabeculectomy glaucoma

Image-guided lens extraction surgery: a systematic review

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International Journal of Ophthalmology(English edition) 2019年第1期12卷 135-151页

作者： Eirini-Kanella Panagiotopoulou Panagiota Ntonti Maria Gkika aristeidis konstantinidis Irfan Perente Doukas Dardabounis Konstantinos Ioannakis Georgios Labiris Department of Ophthalmology University Hospital of Alexandroupolis

A systematic review of the recent literature regarding the current image-guided systems used for cataract surgery or refractive lens exchange was performed based on the PubMed and Google Scholar databases in March 2018. Literature review returned 21 eligible studies. These studies compared image-guided systems with other keratometric devices regarding their accuracy, repeatability and reproducibility in measurement of keratometric values, astigmatism magnitude and axis, as well as in IOL power calculation. Additionally, the image-guided systems were compared with conventional manual ink-marking techniques for the alignment of toric IOLs. In conclusion, image-guided systems seem to be an accurate and reliable technology with measurements of high repeatability and reproducibility regarding the keratometry and IOL power calculation, but not yet interchangeable with the current established and validated keratometric devices. However, they are superior over the conventional manual inkmarking techniques for toric IOL alignment.

关键词： image-guided systems cataract surgery toric intraocular lenses systematic review

Imaging of filtering blebs after implantation of the Ex-PRESS shunt with the use of the Visante optical coherence tomography

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International Journal of Ophthalmology(English edition) 2015年第3期8卷 492-495页

作者： aristeidis konstantinidis Georgios D Panos Magdalini Triantafylla Georgios Labiris Efthimia Tsaragli Zisis Gatzioufas Vassilios Kozobolis Department of Ophthtalmology University Hospital of Alexandroupolis & Eye Institute of Thrace Department of Ophthtalmology Geneva University Hospitals Faculty of Medicine University of Geneva

AIM: To analyze the features of the filtering blebs following implantation of the Ex-PRESS glaucoma device(model P-50) with the aid of the Visante anterior segment optical coherence tomography(AS-OCT)METHODS: Five patients with open angle glaucomas were included in the study. They all underwent implantation of the Ex-PRESS device under a scleral flap. The surgical procedure was augmented with the use of mitomycin C subconjunctivally. The filtering blebs were analyzed with the Visante AS-OCT with the scans taken along the axis of the implantation of the glaucoma ***: All filtering blebs were graded as diffuse functioning. The morphological characteristics of the blebs were similar to those of the *** the use of the Ex-PRESS implant tend to form a characteristic episcleral lake at the site of the plate of the implant. CONCLUSION: The use of the Ex-PRESS implant produces filtering blebs similar to those of the trabeculectomy with the formation of a characteristic episcleral lake at the site of the plate of the implant.

关键词： Ex-PRESS glaucoma optical coherence tomography

Why and how to use the SeqCode

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mLife 2024年第1期3卷 1-13页

作者： Wiliam B.Whitman Maria Chuvochina Brian P.Hedlund Konstantinos T.konstantinidis Marike Palmer Luis M.Rodriguez-R lain Sutcliffe Fengping Wang Deparment of Microbioogy University of GeorgiaAthensGeorgiaUAA Schoolof Chemistry and Molecular Biosciences Australian CentreforEogenomicsThe Universty of QueenslandSt LuciaAustralia University of Nevada Las Vegas Las VegasNevadaUSA Schol of Civil and Environmental Engineering and School of Biological SciencesGeorgia Institute of TechnologyAtlantaGeorgiaUSA Department of Microbiology University of ManitobaWinnipegManitobaCanada School of Life Sciences University of Nevada Las VegasLas VegasNevadaUSA Department of Microbiology and Digital Science Center(DiSC) University of InnsbruckInnsbruckAustria Faculty of Health&Life Sciences Northumbria UniversityNewcastle upon TyneUK School of Oceanography International Center for Deep Life InvestigationShanghai Jiao Tong UniversityShanghaiChina

The SeqCode,formally called the Code of Nomenclature of Prokaryotes Described from Sequence Data,is a new code of nomenclature in which genome sequences are the nomenclatural types for the names of prokaryotic *** similar to the International Code of Nomenclature of Prokaryotes(ICNP)in structure and rules of priority,it does not require the deposition of type strains in international culture ***,it allows for the formation of permanent names for uncultured prokaryotes whose nearly complete genome sequences have been obtained directly from environmental DNA as well as other prokaryotes that cannot be deposited in culture *** the diversity of uncultured prokaryotes greatly exceeds that of readily culturable prokaryotes,the SeqCode is the only code suitable for naming the majority of prokaryotic *** start date of the SeqCode was January 1,2022,and the online Registry(https://***)was created to ensure valid publication of *** SeqCode recognizes all names validly published under the ICNP before *** that date,names validly published under the SeqCode compete with ICNP names for *** a result,species can have only one name,either from the SeqCode or ICNP,enabling effective communication and the creation of unified taxonomies of uncultured and cultured *** SeqCode is administered by the SeqCode Committee,which is comprised of the SeqCode Community and elected administrative *** with an interest in the systematics of prokaryotes is encouraged to join the SeqCode Community and participate in the development of this resource.

关键词： genome sequences metagenome-assembled genomes nomenclature SeqCode

Sequence-discrete species for prokaryotes and other microbes:A historical perspective and pending issues

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mLife 2023年第4期2卷 341-349页

作者： Konstantinos T.konstantinidis School of Civil and Environmental Engineering and School of Biological SciencesGeorgia Institute of TechnologyAtlantaGeorgiaUSA

Whether prokaryotes,and other microorganisms,form distinct clusters that can be recognized as species remains an issue of paramount theoretical as well as practical consequence in identifying,regulating,and communicating about these *** the past decade,comparisons of thousands of genomes of isolates and hundreds of metagenomes have shown that prokaryotic diversity may be predominantly organized in such sequence-discrete clusters,albeit organisms of intermediate relatedness between the identified clusters are also frequently *** evidence suggests,however,that the latter“intermediate”organisms show enough ecological and/or functional distinctiveness to be considered different ***,the area of discontinuity between clusters often—but not always—appears to be around 85%–95%genome-average nucleotide identity,consistently among different *** recent studies have revealed remarkably similar diversity patterns for viruses and microbial eukaryotes as *** high consistency across taxa implies a specific mechanistic process that underlies the maintenance of the *** underlying mechanism may be a substantial reduction in the efficiency of homologous recombination,which mediates(successful)horizontal gene transfer,around 95%nucleotide *** from the 95%threshold(e.g.,species showing lower intraspecies diversity)may be caused by ecological differentiation that imposes barriers to otherwise frequent gene *** this hypothesis that clusters are driven by ecological differentiation coupled to recombination frequency(i.e.,higher recombination within *** groups)is appealing,the supporting evidence remains *** data needed to rigorously test the hypothesis toward advancing the species concept are also outlined.

关键词： average nucleotide identity(ANI) genomovar homologous recombination metagenomics strain

考虑内禀材料长度变化的广义Aifantis应变梯度塑性模型

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Acta Mechanica Sinica 2022年第3期38卷 86-93,I0003页

作者：赵建锋张波刘大彪 Avraam A.konstantinidis 康国政张旭 Institute of Systems Engineering China Academy of Engineering Physics Mianyang 621999 China Applied Mechanics and Structure Safety Key Laboratory of Sichuan Province School of Mechanics and Aerospace Engineering Southwest Jiaotong University Chengdu 610031 China Department of Mechanics School of Aerospace Engineering Huazhong University of Science and Technology Wuhan 430074 China Lab of Engineering Mechanics Aristotle University of Thessaloniki Thessaloniki 54124 Greece

内禀材料长度是应变梯度塑性理论中最重要的参数,被用于成功地解释了微尺度下金属材料的尺寸效应.内禀材料长度在应变梯度框架中通常扮演着平衡量纲的角色,并且其取值依赖于模型.目前,内禀材料长度物理意义、与材料微观结构的关联以及... 详细信息

内禀材料长度是应变梯度塑性理论中最重要的参数,被用于成功地解释了微尺度下金属材料的尺寸效应.内禀材料长度在应变梯度框架中通常扮演着平衡量纲的角色,并且其取值依赖于模型.目前,内禀材料长度物理意义、与材料微观结构的关联以及随变形的演化尚未完全明确.本研究对Aifantis应变梯度塑性模型进行了修正,在其中引入了一个最新提出的幂律形式的内禀材料长度演化关系.在此基础上进一步考虑晶粒尺寸效应,基于Hall-Petch关系对Aifantis应变梯度塑性模型进行了扩展,使用上述修正的模型对细丝扭转的实验结果进行了模拟,研究结果表明,内禀材料长度同时取决于试样尺寸和晶粒尺寸,这些相关性主要由位错间距决定,并可以通过应变硬化指数很好地描述.此外,原始Aifantis模型和修正的Aifantis模型中的内禀材料长度的取值均比Fleck-Hutchinson模型的取值更大.

关键词：应变硬化指数应变梯度塑性理论金属材料试样尺寸晶粒尺寸效应材料微观结构长度变化

Open wedge re-correction high tibial osteotomy in an elderly patient with a varus angulated non-united dome-shaped high tibial osteotomy

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第11期14卷 1054-1058页

作者： Steffen SCHROTER Lukas konstantinidis Tobias M. KRAUS Fabian STUBY Ulrich STOCKLE Thomas FREUDE Department of Traumatology and Reconstructive Surgery BG Trauma Center Department of Orthopaedics and Trauma Surgery University Medical Centre Freiburg

The high tibial osteotomy(HTO)is a wellestablished and commonly used treatment for younger and active patients with a medial unicompartmental osteoarthritis of the knee and varus *** aim of this technique is to shift the load to a functional lateral compartment in order to delay total knee *** dome-shaped HTO was introduced by Blaimont et al.(1975)and later popularized by Maquet(1980).Out of 118 cases,96 cases of overcorrection,13 cases of undercorrection,and 9 cases

关键词： HTO MPTA high

Multispan Balanced Cantilever Bridges: Egnatia Motorway

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Multispan Balanced Cantilever Bridges: Egnatia Motorway

《世界反兴奋剂条例》在希腊的实施——通过第4791/2021号法律

国际桥梁2004年大会

作者： Sergios LAMBROPOULOS Georgios konstantinidis Christos GEORGANOPOULOS Dimitrios konstantinidis Fani ANTONIOU Ueneral Manager Egnatia Odos A.E Thessaloniki GREECE Coordination Head Egnatia Odos A.E Thessaloniki GREECE Design Manager Egnatia Odos A.E Thessaloniki GREECE Structural Engineer Egnatia Odos A.E Thessaloniki GREECE Project Engineer Egnatia Odos A.E Thessaloniki GREECE

＜正＞ The technical characteristics and material quantities of four multispan balanced cantilever bridges constructed along Egnatia Motorway in the Region of Western Macedonia, Greece are presented. Comparisons are made, in terms of material consumption and conclusions are drawn that may provoke further statistical elaboration for all bridges on Egnatia Motorway that will allow accurate cost estimations to be made for bridges to be tendered in the future. In addition, this paper exhibits in brief the design management processes that are employed by Egnatia Odos A.E. for successful management of fast track design and construction procedures necessitated by strict funding deadlines.

关键词： Balanced cantilever bridges material consumption design management.

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体育科研 2022年第6期43卷 35-39页

作者： [希腊]Dimitrios P.Panagiotopoulos [希腊]Zografenia Kallimani [希腊]Konstantinos konstantinidis 赵书涵(译) 雅典大学雅典999028 上海政法学院体育法治研究院上海201701

《世界反兴奋剂条例》(WADC)于2003年首次由世界反兴奋剂机构(WADA)通过并于2004年生效。在希腊,议会根据第3516/2006号法律通过联合国教科文组织《反对在体育运动中使用兴奋剂国际公约》,使这一版本WADC得以生效,并作为国际体育法在本... 详细信息

《世界反兴奋剂条例》(WADC)于2003年首次由世界反兴奋剂机构(WADA)通过并于2004年生效。在希腊,议会根据第3516/2006号法律通过联合国教科文组织《反对在体育运动中使用兴奋剂国际公约》,使这一版本WADC得以生效,并作为国际体育法在本国适用。经修订的2021年实施版WADC于2021年1月1日生效,通过第4791/2021号法律在希腊实施,并据该法成立了国家反兴奋剂组织。WADA禁用名单是第4791/2021号法律的组成部分,应在WADA发布3个月后根据第4791/2021号法律生效,无须国家反兴奋剂组织进一步行动。兴奋剂违规不会自动导致处罚。根据第4791/2021号法律第10条的规定,运动员可在无重大过失或疏忽的情况下,通过向最高体育纠纷解决委员会提起上诉,以及在某些特殊情况下向CAS提起上诉,以取消或缩短禁赛期。强调:国家反兴奋剂组织应为运动员提供一个国内争议解决框架,以促进独立性、效率和成本效益以及各级的一致性和程序公正。

关键词：希腊《世界反兴奋剂条例》第4791/2021号法律