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Bioprinting of radiopaque constructs for tissue engineering and understanding degradation behavior by use of Micro-CT

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Bioactive Materials 2020年第3期5卷 569-576页

作者： Sudipto Datta Shuvodeep Jana Ankita Das arindam chakraborty Amit Roy Chowdhury Pallab Datta Centre for Healthcare Science and Technology Indian Institute of Engineering Science and TechnologyShibpurHowrah711103WBIndia Department of Aerospace Engineering and Applied Mechanics Indian Institute of Engineering Science and TechnologyShibpurHowrah711103WBIndia Indian Institute of Technology KharagpurWest BengalIndia

Bioprinting has emerged as a potential technique to fabricate tissue engineering constructs and in vitro models directly using living cells as a raw material for fabrication,conforming to the heterogeneity and architectural complexity of the *** several of tissue engineering and in vitro disease modelling or surgical planning applications,it is desirable to have radiopaque constructs for monitoring and *** the present work,enhanced radiopaque constructs are generated by substituting Calcium ions with Barium ions for crosslinking of alginate *** constructs are characterized for their structural integrity and followed by cell culture studies to evaluate their *** was followed by the radiopacity *** radiological images obtained by micro-CT technique was further applied to investigate the degradation behavior of the *** conclusion,it is observed that barium crosslinking can provide a convenient means to obtain radiopaque constructs with potential for multi-faceted applications.

关键词： Bioprinting Radiopaque Barium Degradation Cell viability

Oldest Asian Record of Snapping Shrimps(Malacostraca:Alpheidae)from the Kutch Basin,Western India and Associated Biota:Biostratigraphic,Paleoenvironmental and Paleoecological Significance

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Acta Geologica Sinica(English Edition) 2022年第6期96卷 1867-1883页

作者： Vivesh V.KAPUR Kamlesh KUMAR Pranav J.PANDYA Amit KGHOSH arindam chakraborty Anupam SHARMA Gaurav CHAUHAN M.G.THAKKAR Birbal Sahni Institute of Palaeosciences 53University RoadLucknow 226007India Department of Biology Shri R.R.Lalan CollegeBhujKachchh DistrictGujaratIndia Institute of Earth Sciences Academia SinicaTaipeiTaiwan 11529China Department of Earth and Environmental Science K.S.K.V.Kachchh UniversityBhujKachchh DistrictGujaratIndia

The oldest Asian record of alpheid shrimps,assigned to genus Alpheus,based on snapping claw fingertips from the Miocene Khari Nadi Formation in the Kutch Basin,western India reported herein,extends the fossil record of the family Alpheidae from Asia by~22 million *** early Miocene(Aquitanian)age is estimated based on the associated assemblage of calcareous nannofossils,Sphenolithus disbelemnos,Cyclicargolithus floridanus,and Reticulofenestra *** co-occurring microbiota includes bony fish otolith remains,identified as“genus Gobiidarum”,isolated teeth of Dasyatis rays,Sphyrna sharks,and teleosts,ctenoid and placoid scales,ostracods,belonging to the genera Paractinocythereis,Alocopocythere,Ruggieria,Aglaiocypris,Bairdoppilata,and echinoid *** together,the microfossil assemblage and data from chemical analyses using Energy Dispersive Spectroscopy,X-Ray Diffraction and Wavelength Dispersive X-Ray Fluorescence of host and associated lithologies suggests prevalence of a shallow(neritic)to coastal marine(intertidal)depositional *** present investigation also provides the oldest fossil evidence on the co-occurrence of Alpheus and gobiids(based on otoliths)that strongly advocates that the mutualistic association between these animal groups had developed by the Aquitanian.

关键词： biostratigraphy Crustacea Caridea Elasmobranchs Gobiidae invertebrate and vertebrate paleontology nannofossils Oligocene-Miocene Indian subcontinent

Prevalence of Mycobacterium tuberculosis Strains Isolated from Both Pulmonary and Extra Pulmonary Samples and Their Resistance to Rifampicin: A Study from Kolkata and Surrounding Suburbs

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Journal of Tuberculosis Research 2016年第2期4卷 61-71页

作者： Soma chakraborty arindam chakraborty Tathagata Talukder Mita Mukherjee Tridip Chatterjee Department of Microbiology Suraksha Diagnostics DD-18/1 Kolkata India Suraksha Genomics (R & D Division of Suraksha Diagnostics) DD-18/1 Kolkata India

Tuberculosis (TB) is one of the major causes of morbidity and mortality worldwide. In India, nearly 1.8 million new cases of TB are reported annually, which accounts for a fifth of new cases in the world—greater than in any other country. Anti-tubercular drugs (ATDs) have been used for decades, and widespread resistance to them is a very serious public health concern in any part of the world. Aim of this study was to determine the prevalence of Rifampicin (the first line Anti-TB drug) resistance among both pulmonary and extra-pulmonary samples tested positive for Mycobacterium tuberculosis and thereby predict the prevalence of Multi-drug resistant (MDR) tuberculosis in Kolkata and its Suburban regions. All 331 randomly collected clinical samples (both Pulmonary and Extra Pulmonary) were initially screened by Zeihl-Neelsen AFB staining followed by culture on BacT/Alert 3D system and on Lowenstein-Jensen medium and the positive samples were subjected to detection of Mycobacterium tuberculosis complex (MTBC) and simultaneous analysis of Rifampicin resistance by Xpert MTB/RIF assay. Out of the 51 (15.40%) culture positive samples, 13.7% of pulmonary samples and 9.09% of extra-pulmonary samples were Rifampicin resistant. The prevalence of Rifampicin resistant TB in our study is high and the possible reasons can be mixing of new as well as retreatment cases and smaller sample size but, yet it can help Government and public health regulatory bodies to formulate adequate strategies to fight against drug resistant tuberculosis, especially in this part of the world.

关键词： Tuberculosis (TB) Multi Drug Resistant TB (MDR-TB) Rifampicin Resistant TB GeneXpert

Study of flow characteristics within randomly distributed submerged rigid vegetation

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Journal of Hydrodynamics 2019年第2期31卷 358-367页

作者： Paromita chakraborty arindam Sarkar School of Civil Engineering Kalinga Institute of Industrial Technology(KIIT)Deemed to be UniversityBhubaneswarOdishaIndia School of Infrastructure Indian Institute of Technology(IIT)Bhubaneswar AurgulBhubaneswarOdishaIndia

Flow through submerged rigid vegetation has been studied both analytically and *** Reynolds stress,present in the governing equation,has been modeled using one of the turbulent stress equations,adopted in numerous *** adva ntage of this turbulent stress model is to replace the mixing length non linear term of the stress with a linear relatio n between stress and the velocity *** velocity field and shear stress are obtained by solving the governing force balance equation numerically.A correlation,validated with the experimental results,has been developed for the relevant non-dimensional numbers.

关键词： Submerged vegetation Reynolds stress drag force stream wise velocity

Brewing and biochemical characterization of Camellia japonica petal wine with comprehensive discussion on metabolomics

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Food Production, Processing and Nutrition 2022年第1期4卷 366-382页

作者： Soumya Majumder arindam Ghosh Sourav chakraborty Malay Bhattacharya Molecular Biology and Tissue Culture Laboratory Department of Tea ScienceUniversity of North BengalSiliguriDarjeelingWest Bengal 734013India Postgraduate Department of Botany Darjeeling Government CollegeDarjeelingWest Bengal 734101India

A novel wine has been developed from Camellia japonica’s petal by fermenting the decoction with Saccharomyces cerevisiae or brewer’s yeast. pH, brix, specific gravity and alcohol percentage were tested to study the physicochemical properties of the wine. Qualitative tests indicated presence of phenols such as flavonoids, coumarins;protein;glyco-sides;glycerin;terpenoids;steroids;and fatty acids in the wine. Total phenol content was found high in the decoction and in its fermented form as well. In vitro biological activities such as antioxidant activity, antidiabetic activity and lipid peroxidation inhibition power were assessed in samples. Furthermore, GC-MS analysis helped to detect volatiles present in the unfermented decoction and understand the effect of fermentation on its changing metabolome while column chromatography assisted the separation of solvent-based fractions. Notable outcomes from this study were detection of bioactive compound quinic acid in the decoction and a proposed pathway of its metabolic breakdown after fermentation. Results of this research revealed biochemical and physicochemical acceptability of this wine prepared from an underutilized flower.

关键词： Camellia Quinic acid GC-MS Fermentation Wine

Production of fermented tea petal decoction with insights into in vitrobiochemical tests,antioxidant assay and GC-MS analysis

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Food Production, Processing and Nutrition 2021年第1期3卷 406-415页

作者： Soumya Majumder Sumedha Saha arindam Ghosh Sukanya Acharyya Sahadeb Sarkar Sourav chakraborty Malay Bhattacharya Molecular Biology and Tissue Culture Laboratory Department of Tea ScienceUniversity of North BengalSiliguriDarjeelingWest Bengal Pin-734013India

This research work was designed to attempt and propose the first report on production and biochemical characterization of fermented tea flower petal decoction or simply tea petal *** tea petal decoction and brewer’s yeast or Saccharomyces cerevisiae were co-cultured for *** activity and chromatographic separation of potential candidates were *** investigations for qualitative characters on this fermented broth revealed the presence of steroids,tannin,flavonoids,phenol,cardiac glycosides,coumarin,caffeine *** manufactured fermented broth showed high free radical scavenging activity after 2 months of *** DPPH scavenging activities were also observed in solvent fractions of acetone,ethanol and *** antioxidant activity,alcohol percentage and other qualities were seen to be gradually increased during *** chromatography-mass spectrometry analysis revealed the presence of 44 compounds including many potential antioxidant molecules and other bioactive ***,presence of alcohol with medicinally active compounds and antioxidant activity will make it as acceptable as a good wine and tea flower as economically functional.

关键词： Tea petal Antioxidant GC-MS Fermentation brewer’s yeast

Assessment of the fraction of bed load concentration towards the sediment transport of a monsoon-dominated river basin of Eastern India

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Journal of Geographical Sciences 2023年第5期33卷 1023-1054页

作者： KAR Rohan SARKAR arindam School of Infrastructure Indian Institute of Technology BhubaneswarArgulKhordhaOdisha 752050India

Given the challenges of re-creating complex bed load(BL)transport processes in rivers,models are preferred over gathering and examining field *** highlight of the present research is to develop an approach to determine the ungauged bed load concentration(BLC_(u))utilizing the measured suspended sediment concentration(SSC)and hydraulic variables of the last four decades for the Mahanadi River *** technique employs shear stress and SSC equations for turbulent open channel ***,the predicted BLC_(u)is correlated with SSC using a power relation to estimate BLC_(u)on the river and ***,different BL functions(BLF)efficiency is assessed across *** model predicted BLC_(u)is comparable with the published data for sandy rivers and falls within±20%.Outliers in hydraulic and sedimentological statistics significantly influence estimating the BL fraction apart from higher relative ratios and catchment *** constants of power functions are physically linked to sediment transport configuration,mechanism,and inflow to the *** stream power-based BLF best predicts the BL transport,followed by shear stress and unit discharge *** disparity in the estimation of BLC_(u)results from station-specific physical factors,sampling data dispersion,and associated uncertainties.

关键词： Mahanadi River Basin ungauged bed load concentration suspended sediment concentration correlations bed load functions

A Kenmotsu Metric as a *-conformal Yamabe Soliton with Torse Forming Potential Vector Field

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Acta Mathematica Sinica,English Series 2021年第12期37卷 1896-1908页

作者： Soumendu ROY arindam BHATTACHARYYA Department of Mathematics Jadavpur UniversityKolkata 700032India

The purpose of the present paper is to deliberate *-conformal Yamabe soliton,whose potential vector field is torse-forming on Kenmotsu ***,we have shown the nature of the soliton and find the scalar curvature when the manifold admitting *-conformal Yamabe soliton on Kenmotsu ***,we have evolved the characterization of the vector field when the manifold satisfies *-conformal Yamabe *** we have embellished some applications of vector field as torse-forming in terms of *-conformal Yamabe soliton on Kenmotsu *** have developed an example of *-conformal Yamabe soliton on 3-dimensional Kenmotsu manifold to prove our findings.

关键词： *-conformal Yamabe soliton torse forming vector field conformal Killing vector field Kenmotsu manifold

Optimum lateral extent of soil domain for dynamic SSI analysis of RC framed buildings on pile foundations

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Frontiers of Structural and Civil Engineering 2020年第1期14卷 62-81页

作者： Nishant SHARMA Kaustubh DASGUPTA arindam DEY Department of Civil Engineering Indian Institute of Technology GuwahatiGuwahati 781039India

This article describes a novel approach for deciding optimal horizontal extent of soil domain to be used for finite element based numerical dynamic soil structure interaction(SSI)*** model for a 12 storied building frame,supported on pile foundation-soil system,is developed in the finite element based software framework,*** different structure-foundation configurations are analyzed under different ground motion *** extent of soil domain,along with the soil properties,were varied exhaustively for a particular structural *** on the reduction in the variation of acceleration response at different locations in the SSI system(quantified by normalized root mean square error,NRMSE),the optimum lateral extent of the soil domain is prescribed for various structural widths,soil types and peak ground acceleration levels of ground *** to the past studies,error estimation analysis shows that the relationships prescribed in the present study are credible and more inclusive of the various factors that influence *** relationships can be readily applied for deciding upon the lateral extent of the soil domain for conducting precise SSI analysis with reduced computational time.

关键词： soil structure interaction optimum lateral extent of soil domain length multi-storyed framed building pile foundation OpenSEES L-K boundaries dynamic analysis