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Portal hypertensive duodenal polyp:A case report

World Journal of Gastroenterology 2007年第9期13卷 1451-1452页

作者： Jean-David Zeitoun ariane chryssostalis Benoit Terris frederic prat Marianne Gaudric Stanislas Chaussade Department of Gastroenterology Cochin Hospital Assistance Publique des Hpitaux de Paris Paris France Department of Pathology Cochin Hospital Assistance Publique des Hpitaux de Paris Paris France

Abnormalities of gastric mucosa in patients with portal hypertension are well documented. Manifestations of portal hypertension in small bowel and colon are less common. Colonic polypoid lesions microscopically consisting of a normal mucosa, with dilatation of submucosal vessels, have been described. We here report the first case of portal hypertensive duodenal polyp, responsible for gastro-intestinal bleeding. Endoscopic treatment turned out to be successful.

关键词： Gastrointestinal bleeding Cirrhosis Portal hypertension Small bowell Endoscopy

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Helpfulness of the combination of acetic acid and FICE in the detection of Barrett's epithelium and Barrett's associated neoplasias

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World Journal of Gastroenterology 2012年第16期18卷 1921-1925页

作者： Marine Camus Romain Coriat Sarah Leblanc Catherine Brezault Benoit Terris Elise Pommaret Marianne Gaudric ariane chrys.os.alis.frederic prat Stanislas Chaussade Gastroenterology and Endoscopy Unit Cochin HospitalAssistance Publique-Hpitaux de ParisUniversité Paris DescartesSorbone Paris Cité75014 ParisFrance Pathology Department Cochin HospitalAssistance Publique-Hpitaux de ParisUniversité Paris DescartesSorbone Paris Cité75014 ParisFrance

AIM:To investigate the mucosal morphology in Barrett's oesophagus by chromo and magnifying ***:A prospective pilot study at a tertiary medical centre was conducted to evaluate the use of acetic acid pulverisation combined with virtual chromoendoscopy using Fujinon intelligent chromoendoscopy(FICE) for semiological characterization of the mucosal morphology in Barrett's oesophagus and its neoplastic *** endoscopy using high definition whitelight,2% acid acetic pulverisation and FICE with high definition videoendoscopy were performed in 20 patients including 18 patients who presented with aspects of Barrett's oesophagus at endoscopy *** patients used as controls had normal endoscopy and histological ***,videos were watched blind from histological results by three trained FICE technique ***:The videos of patients with high-grade dysplasia showed an irregular mucosal pattern in 14% using high definition white light endoscopy and in 100% using acid acetic-FICE *** did not identify irregular vascular patterns using high definition white light endoscopy,while acid acetic-FICE combined visualised one in 86% of ***:Combined acetic acid and FICE is a promising method for screening high-grade dysplasia and early cancer in Barrett's oesophagus.

关键词： Acetic acid Barrett's metaplasia Chromoendoscopy Fujinon intelligent chromoendoscopy

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Optimization of the generator settings for endobiliary radiofrequency ablation

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World Journal of Gastrointestinal Endoscopy 2015年第16期7卷 1222-1229页

作者： Maximilien Barret Sarah Leblanc ariane Vienne Alexandre Rouquette frederic Beuvon Stanislas Chaussade frederic prat Department of Gastroenterology Cochin Hospital Faculty of Medecine Paris-Descartes University Department of Pathology Cochin Hospital

AIM:To determine the optimal generator settings for endobiliary radiofrequency ablation. METHODS:Endobiliary radiofrequency ablation was performed in live swine on the ampulla of Vater,the common bile duct and in the hepatic parenchyma. Radiofrequency ablation time,"effect",and power were allowed to vary. The animals were sacrificed two hours after the procedure. Histopathological assessment of the depth of the thermal lesions was performed. RESULTS:Twenty-five radiofrequency bursts were applied in three swine. In the ampulla of Vater(n = 3),necrosis of the duodenal wall was observed starting with an effect set at 8,power output set at 10 W,and a 30 s shot duration,whereas superficial mucosal damage of up to 350 μm in depth was recorded for an effect set at 8,power output set at 6 W and a 30 s shot duration. In the common bile duct(n = 4),a 1070 μm,safe and efficient ablation was obtained for an effect set at 8,a power output of 8 W,and an ablation time of 30 s. Within the hepatic parenchyma(n = 18),the depth of tissue damage varied from 1620 μm(effect = 8,power = 10 W,ablation time = 15 s) to 4480 μm(effect = 8,power = 8 W,ablation time = 90 s). CONCLUSION:The duration of the catheter application appeared to be the most important parameter influencing the depth of the thermal injury during endobiliary radiofrequency ablation. In healthy swine,the currently recommended settings of the generator may induce severe,supratherapeutic tissue damage in the biliary tree,especially in the high-risk area of the ampulla of Vater.

关键词： Endobiliary radiofrequency ablation Biliary strict

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