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Particuology 2024年第7期90卷 452-469页

作者： Abdulmuttalip ari Suat Akbulut Department of Civil Engineering Yildiz Technical UniversityIstanbul34220Turkey

In this study,the effects of particle shape of rigid sand and soft rubber materials on macro-scale shear response were reasoned based on micro-scale *** this purpose,first,the shape properties of three different sand and two different rubber samples were quantified using image processing techniques,and the contact model parameters were calibrated through physical *** direct shear test was simulated in a two-dimensional discrete element software with realistic particle *** soft nature of rubber particles was reflected using body-centered cubic packing with a linear-parallel bond contact *** a result,coordination number,distribution of contact forces(i.e.,strong contact,and fabric anisotropy),and contact sliding were derived by the numerical *** has been observed that the particle shape leads to distinctive micro-scale responses due to the variations in the stiffness of the contacts.

关键词： Particle shape Sand Rubber Shear response Micro-scale response Discrete element method

Using on-site liver 3-D reconstruction and volumetric calculations in split liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2016年第6期15卷 587-592页

作者： Trevor W Reichman Brittany Fiorello Ian Carmody Humberto Bohorquez ari cohen John Seal David Bruce George E Loss Ochsner Multi-Organ Transplant Institute Ochsner Medical Center

BACKGROUND： Split liver transplantation increases the number of grafts available for transplantation. Pre-recovery assessment of liver graft volume is essential for selecting suitable recipients. The purpose of this study was to determine the ability and feasibility of constructing a 3-D model to aid in surgical planning and to predict graft weight prior to an in situ division of the donor liver. METHODS： Over 11 months, 3-D volumetric reconstruction of 4 deceased donors was performed using Pathfinder Scout liver volumetric software. Demographic, laboratory, operative, perioperative and survival data for these patients along with donor demographic data were collected prospectively and analyzed retrospectively. RESULTS： The average predicted weight of the grafts from the adult donors obtained from an in situ split procedure were 1130 g （930-1458 g） for the extended right lobe donors and 312 g （222-396 g） for left lateral segment grafts. Actual adult graft weight was 92% of the predicted weight for both the extended right grafts and the left lateral segment grafts. The predicted and actual graft weights for the pediatric donors were 176 g and 210 g for the left lateral segment grafts and 308 g and 280 g for the extended right lobe grafts,respectively. All grafts were transplanted except for the right lobe from the pediatric donors due to the small graft ***： On-site volumetric assessment of donors provides useful information for the planning of an in situ split and for selection of recipients. This information may expand the donor pool to recipients previously felt to be unsuitable due to donor and/or recipient weight.

关键词： split liver transplantation reduced-size liver transplantation 3-D reconstruction

Ophthalmic exam and ophthalmology residents’ subspecialty preference

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 359-364页

作者： ari Leshno Daf Shalev Daphna Landau Prat Goldschleger Eye Institute Sheba Medical CenterTel Hashomer 5262000Israel Sackler Faculty of Medicine Tel Aviv UniversityTel Aviv 6997801Israel Department of Ophthalmology Edith Wolfson Medical CenterHolon 5822012Israel

AIM:To evaluate residents’perceptions and attitudes toward the various aspects of a comprehensive ophthalmic examination,and to determine if these factors correlate with their choices for fellowship and future career ***:This is a cross-sectional study.A questionnaire on the perception of the ophthalmic exam was sent via SurveyMonkey to ophthalmology residents throughout *** of them(one-half of all ophthalmology residents in 2019)completed *** first part related to how they perceived each component of the ophthalmic *** second part related to their future fellowship *** Chi-squared test was used to compare categorical variables and Student’s t-test and One-way ANOVA were used to compare continuous *** logistic regression analysis was applied as needed to detect interactions between variables and to exclude confounder ***:Slit-lamp examination of the anterior and posterior segments ranked as the most likeable aspects,whereas gonioscopy,ocular motility examination and visual acuity assessment were least *** segment and retina subspecialties were the ones most sought ***-nine respondents(61.3%)noted a direct correlation between their preferred parts of comprehensive ophthalmic evaluations and their choice of *** of selected components of those evaluations were significantly associated with responders’intentions to pursue anterior segment,retina,or oculoplastic fellowships(P<0.05).CONCLUSION:Perspectives of residents toward the ophthalmic examination,and most specifically its individual components,play an important role in their choice of subspecialty training.

关键词： residency subspecialty ophthalmic examination career choice ophthalmology

Links between donor macrosteatosis,interleukin-33 and complement after liver transplantation

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World Journal of Transplantation 2020年第5期10卷 117-128页

作者： Kelley Núñez Mohammad Hamed Daniel Fort David Bruce Paul Thevenot ari cohen Institute of Translational Research Ochsner Clinic FoundationNew OrleansLA 70121United States Center for Outcomes and Health Services Research Research AdministrationOchsner Clinic FoundationNew OrleansLA 70121United States Multi-Organ Transplant Program Ochsner Clinic FoundationNew OrleansLA 70121United States

BACKGROUND As prevalence of nonalcoholic fatty liver disease increases in the population,livers with steatosis will continue to infiltrate the donor *** utilization of these extended criteria grafts is paramount given the increased risk associated with their use in *** factors that can predict liver dysfunction immediately after transplantation with macrosteatotic grafts are *** To understand the relationship between interleukin-33(IL-33)and complement in recipients immediately following liver reperfusion as a marker of liver *** Cohort consisted of patients who received a liver transplant from September 2016–September 2019 at our *** variables were retrospectively extracted from the electronic medical ***-table donor biopsies were obtained with donor steatosis percentage retrospectively determined by a boardcertified *** samples were available immediately following liver *** of plasma IL-33 and complement proteins,C3a and C5a,were determined by enzyme-linked immunosorbent *** mRNA expression,RNA was extracted from donor biopsies and used against a 780 gene *** Cohort consisted of 99 donor and *** median age was 45 years and 55%*** had a median age of 59 years with 62%*** main etiologies were alcoholic hepatitis,nonalcoholic steatohepatitis,and hepatocellular *** MELD-Na at transplant was *** were grouped based on moderate macrosteatosis(≥30%).Recipients implanted with moderate macrosteatotic grafts had significantly higher peak alanine aminotransferase/aspartate aminotransferase(P<0.001 and P<0.004),and increased incidence of early allograft dysfunction(60%compared to 18%).Circulating IL-33 levels were significantly elevated in recipients of≥30%macrosteatotic grafts(P<0.05).Recipients with detectable levels of circulating IL-33 immediately following reperfusion had significantly highe

关键词： Liver transplantation Interleukin-33 Donor macrosteatosis Complement Early allograft dysfunction Reperfusion

Assessment of corrected time-step method for nominal ionospheric gradient calculation: A comparative analysis with spatial approaches

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Earth and Planetary Physics 2024年第4期8卷 641-649页

作者： Slamet Supriadi Prayitno Abadi Susumu Saito Harry Bangkit Dwiko Unggul Prabowo Adi Purwono Ginaldi ari Nugroho Research Center for Smart Mechatronics National Research and Innovation Agency(BRIN)BandungIndonesia Research Center for Climate and Atmosphere BRINBandungIndonesia School of Electrical Engineering Telkom UniversityKab.BandungIndonesia Electronic Navigation Research Institute National Institute of MaritimePort and Aviation TechnologyTokyoJapan Research Center for Space BRINBandungIndonesia

The effect of ionospheric delay on the ground-based augmentation system under normal conditions can be mitigated by determining the value of the nominal ionospheric gradient(σvig).The nominal ionospheric gradient is generally obtained from Continuously Operating Reference Stations data by using the spatial single-difference method(mixed-pair,station-pair,or satellite-pair)or the temporal single-difference method(time-step).The time-step method uses only a single receiver,but it still contains ionospheric temporal *** introduce a corrected time-step method using a fixed-ionospheric pierce point from the geostationary equatorial orbit satellite and test it through simulations based on the global ionospheric *** also investigate the effect of satellite paths on the corrected time-step method in the region of the equator,which tends to be in a more north–south direction and to have less coverage for the east–west ionospheric *** study also addresses the limitations of temporal variation correction coverage and recommends using only the correction from *** processes are developed under simulations because observational data are still difficult to *** findings demonstrate that the corrected time-step method yieldsσvig values consistent with other approaches.

关键词： ground-based augmentation system nominal ionospheric gradient time-step correction global ionospheric model

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数字支付垄断中的银行竞争与家庭隐私

新金融 2024年第3期 36-43页

作者： Itai Agur Anil ari Giovanni Dell'ariccia 李丽丽(翻译) 周正铭(翻译) 国际货币基金组织不详

贷款人可以利用家庭的支付数据来推断他们的信誉。当家庭重视隐私时,他们就会在保护隐私和信贷条件之间做出权衡。本文研究了引入更具信息入侵性的数字支付工具是如何对家庭的现金使用、信贷获取和福利产生影响,以及私人和社会最优是如... 详细信息

贷款人可以利用家庭的支付数据来推断他们的信誉。当家庭重视隐私时,他们就会在保护隐私和信贷条件之间做出权衡。本文研究了引入更具信息入侵性的数字支付工具是如何对家庭的现金使用、信贷获取和福利产生影响,以及私人和社会最优是如何分化的。新技术正在从根本上改变支付和信贷提供的方式,并为数据垄断创造了前所未有的空间。技术垄断者控制着新支付方式的入侵性,操纵家庭和寡头垄断银行之间的信息不对称,以获取比自己放贷更有利可图的数据合同。自由放任的均衡需要一种比最优状态更具入侵性的数字支付工具,为监管提供窗口。本刊编译此篇国际货币基金组织的工作论文,以期为读者带来启示。

关键词：数字支付家庭隐私金融中介大数据数据监管

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遥遥领先！超越西方数百年的中国古代数学

环球人文地理 2024年第11期 100-103页

作者：汪洋 ari 摄影师Sean Wikipedia 摄图网

以盈补虚、因木望山、幻方、珠算、隙积术……华夏沃土不仅绽放着多彩的文化之花，也厚植了无数启迪心智的智慧之树。我们的祖先在长期生产劳动中掌握了丰富且实用的数学知识，应用在天文历法、土地测量、买卖交易、器物制作与织绣纹样...

以盈补虚、因木望山、幻方、珠算、隙积术……华夏沃土不仅绽放着多彩的文化之花，也厚植了无数启迪心智的智慧之树。我们的祖先在长期生产劳动中掌握了丰富且实用的数学知识，应用在天文历法、土地测量、买卖交易、器物制作与织绣纹样等领域，不仅解决了许多生存与生活难题，也在世界数学史上留下瞩目成就。

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“Weighing the risk”: Obesity and outcomes following liver transplantation

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World Journal of Hepatology 2015年第11期7卷 1484-1493页

作者： Trevor W Reichman George Therapondos Maria-Stella Serrano John Seal Rachel Evers-Meltzer Humberto Bohorquez ari cohen Ian Carmody Emily Ahmed David Bruce George E Loss Multi-Organ Transplant Institute Ochsner Medical Center

Obesity is on the rise worldwide. As a result, unprecedented rates of patients are presenting with end stage liver disease in the setting of non-alcoholic fatty liver disease(NAFLD) and are requiring liver transplantation. There are significant concerns that the risk factors associated with obesity and the metabolic syndrome might have a detrimental effect on the long term outcomes following liver transplantation. In general, short term patient and graft outcomes for both obese and morbidly obese patients are comparable with that of non-obese patients, however, several studies report an increase in peri-operative morbidity and increased length of stay. Continued studies documenting the long-term outcomes from liver transplantation are needed to further examine the risk of recurrent disease(NAFLD) and also further define the role risk factors such cardiovascular disease might play long term. Effective weight reduction in the post liver transplant setting may mitigate the risks associated with the metabolic syndrome long-term.

关键词： End stage liver disease Obesity Morbidobesity Non-alcoholic steatohepatitis Non-alcoholicfatty liver disease Cirrhosis Liver transplantation

Ataxia-telangiectasia mutated plays an important role in cerebellar integrity and functionality

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Neural Regeneration Research 2023年第3期18卷 497-502页

作者： Yulia Mitiagin ari Barzilai Department of Neurobiology the School of NeurobiologyBiophysicsMolecular Biology and BiochemistryGeorge S.WiseFaculty of Life SciencesTel Aviv UniversityTel AvivIsrael Sagol School of Neurosciences Tel Aviv UniversityTel AvivIsrael

Accumulating evidence indicates that ataxia-telangiectasia mutated kinase is critical for maintaining cellular homeostasis and that it has both nuclear and cytoplasmic ***,the functions of ataxia-telangiectasia mutated that when lost lead to cerebellar degeneration are still *** this review,we first describe the role of ataxia-telangiectasia mutated in cerebellar *** addition to its canonical nuclear functions in DNA damage response circuits,ataxia-telangiectasia mutated functions in various cytoplasmic and mitochondrial processes that are critically important for cellular *** discuss these functions with a focus on the role of ataxia-telangiectasia mutated in maintaining the homeostatic redox ***,we describe the unique functions of ataxia-telangiectasia mutated in various types of neuronal and glial cells including cerebellar granule neurons,astrocytes,and microglial cells.

关键词： ataxia telangiectasia ATM cerebellum DNA damage response double-strand breaks mitochondrial dysfunction oxidative stress single-strand breaks

Upgrading process of palm empty fruit bunches as alternative solid fuel: a review

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Clean Energy 2023年第6期7卷 1173-1188页

作者： Toto Hardianto ari Akbariyanto Wenas Firman Bagja Juangsa Energy Conversion Research Group Faculty of Mechanical and Aerospace EngineeringInstitut Teknologi BandungWest JavaIndonesia Research Center for New and Renewable Energy Institut Teknologi BandungWest JavaIndonesia Mechanical Engineering Study Program Faculty of Mechanical and Aerospace EngineeringInstitut Teknologi BandungWest JavaIndonesia

A total of 37.5 million tons of palm empty fruit bunches(EFBs)produced in Indonesia in 2018 have the potential to be used as an alternative eco-friendly solid ***,a pretreatment process is necessary to increase the heating value and reduce the po-tassium content of *** methods can be employed to improve the characteristics of EFBs as a solid fuel,such as drying and torrefaction to increase the heating value and the leaching process for reducing the potassium content of *** main concept of increasing the heating value is to increase the fuel content,which is *** drying,the carbon ratio can be increased by reducing the moisture content and,through torrefaction,the carbon ratio could be increased due to the decomposition of ligno-cellulose.A simple way to reduce the potassium content of EFBs is the leaching *** types of leaching treatment have been studied before:soaking and stirring *** study reviews those methods to make EFBs more suitable as a solid fuel with a high heating value and less potassium *** the carbon content in EFBs is crucial for enhancing their heating value as a *** and torrefaction decrease the moisture content and modify the chemical structure,resulting in higher carbon *** leaching process effectively reduces the potassium content of EFBs and stirring treatment is more effective than immersion *** positively affects leaching by decreasing the potassium content,while hydrophobicity may hinder leaching by re-pelling *** high moisture content of leached EFBs requires additional energy for evaporation during torrefaction,resulting in a lower energy density yield compared with raw *** may also be required to account for the decreased mineral content,which functions as a torrefaction catalyst in EFBs that have not been leached.

关键词： biomass EFB solid fuel torrefaction upgrading