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Postpartum Family Planning at the Timbuktu Hospital in Mali

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Open Journal of Obstetrics and Gynecology 2024年第7期14卷 1074-1082页

作者： Kassogué Djibril Samaké Alou Dolo Akoro Sogoba Seydou Touré Lahaou Cissouma Assetou Kassogué Abdoulaye Maiga Mariam Mariko Souleymane Kantako Karamoko Ongoiba Oumar Sanogo Ooumar Traoré Bassirima Sidibé Idrissa mandé Kassambara Youssouf Traoré Halima Timbuktu Hospital Bamako Mali Commune VI Bamako District Hospital Bamako Mali CHU Point G Bamako Bamako Mali Sikasso Hospital Bamako Mali nianankoro Fomba Sgou Hospital Bamako Mali

Introduction: Postpartum family planning is the prevention of pregnancies during the 12 months following childbirth. Few studies have been devoted to postpartum family planning in Mali. Our work will contribute to reducing unmet need for family planning. Objective: To study the use of contraceptive methods in the postpartum period in the obstetrics and gynecology unit of Timbuktu hospital. Materials and Methods: This was a descriptive and analytical cross-sectional study with prospective collection of data from January 1, 2022 to December 31, 2023. All women who gave birth having chosen and benefited from a contraceptive method were included. The statistical test used was the Fisher test with a significance threshold fixed at 5%. Results: The frequency of contraception in the postpartum period was 17.03%. The average age of clients was 26.14% with extremes of 14 and 45 years. They were paupiparous at 56.4% with an inter-birth interval of less than 12 months at 12.3%. More than half of the counseling (58.5%) was done during postnatal visits. The methods chosen were implants at 48.1%, injectable progestins at 21.3%, intrauterine device at 14.7%, miro-progestin pills at 13.5%, tubal ligation at 1 .4% and condoms at 1%. The regular follow-up rate was 51.1% of cases and 25.6% had no follow-up. Conclusion: The overall rate of postpartum family planning of 17.08% remains low. Improving FP staff skills will reduce unmet needs and contribute to increasing contraceptive prevalence in Timbuktu.

关键词： Family Planning Postpartum Counseling Contraceptive Methods Timbuktu Hospital

A Th2-score in the tumor microenvironment as a predictive biomarker of response to Bacillus Calmette Guérin in patients with non-muscle invasive bladder carcinoma:A retrospective study

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Oncology Research 2023年第2期31卷 207-220页

作者： GUSTAVO MARTÍn VILLOLDO MARÍA TERESA POMBO MARIAnA ARIS JOAQUÍn CHEMI PABLO mandÓ SUPRIYA nAGARAJU JUAn CAMEAn ADRIÁn BURIOnI DEBORAH EGEA MORA AMAT JOSÉLEÓn MELLADO JOSÉMORDOH ALBERTO VILLAROnGA MARÍA MARCELA BARRIO Urology Department Instituto Alexander FlemingCiudad Autónoma de Buenos Aires1426Argentina Immunohistochemistry Department Instituto Alexander FlemingCiudad Autónoma de Buenos Aires1426Argentina Centro de Investigaciones Oncológicas Fundación Cáncer FUCACiudad Autónoma de Buenos Aires1426Argentina Urology Department MD Anderson Cancer CenterHoustonTX77030USA Pathology Department Instituto Alexander FlemingCiudad Autónoma de Buenos Aires1426Argentina

Intravesical Bacillus Calmette Guerin(BCG)is the gold standard therapy for intermediate/high-risk nonmuscle invasive bladder cancer(nMIBC).However,the response rate is~60%,and 50%of non-responders will progress to muscle-invasive *** induces massive local infiltration of inflammatory cells(Th1)and ultimately cytotoxic tumor *** searched for predictive biomarker of BCG response by analyzing tumor-infiltrating lymphocyte(TIL)polarization in the tumor microenvironment(TME)in pre-treatment ***-treatment biopsies from patients with nMIBC who received adequate intravesical instillation of BCG(n=32)were evaluated retrospectively by *** polarization was assessed by quantifying the T-Bet+(Th1)and GATA-3+(Th2)lymphocyte ratio(G/T),and the density and degranulation of EPX+*** addition,PD-1/PD-L1 staining was *** results correlated with BCG *** most non-responders,Th1/Th2 markers were compared in pre-and post-BCG *** was 65.6%in the study *** responders had a higher G/T ratio and a greater number of degranulated EPX+*** combined into a Th2-score showed a significant association with higher scores in responders(p=0.027).A Th2-score cut-off value>48.1 allowed discrimination of responders with 91%sensitivity but lower ***-free survival was significantly associated with the Th2-score(p=0.007).In post-BCG biopsies from recurring patients,TILs increased Th2-polarization,probably reflecting BCG failure to induce a pro-inflammatory status and,thus,a lack of ***-L1/PD-1 expression was not associated with the response to *** results support the hypothesis that a preexisting Th2-polarized TME predicts a better response to BCG,assuming a reversion to Th1 polarization and antitumor activity.

关键词： non-muscle invasive bladder cancer BCG predictive biomarkers Lymphocyte polarization

Influence of meditation on estate planning decisions:evidence from Indian survey data

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Financial Innovation 2017年第1期3卷 415-432页

作者： Amarjit Gill Harvinder S.mand John D.Obradovich neil Mathur Edwards School of Business The University of Saskatchewan25 Campus DriveSaskatoonSK S7N-5A7Canada University College Benra(Dhuri) District SangrurEast PunjabIndia Liberty University 1971 University BlvdLynchburgVA 24502USA College of Management and Technology Walden University100 Washington Avenue SouthMinneapolisMN 55401USA

Background:Intestate death can lead to the distribution of assets against the personal wishes of the deceased and is a problem in India,as 80%of Indians die without making a last *** the concepts of decision theory(i.e.,the theory of choice),stewardship theory,agency theory,and signaling theory,the purpose of this study is to examine the influence of meditation on estate planning *** study also seeks to extend previous findings on the influence of religious beliefs on the estate planning decisions of Canadians to that of ***:Employed and self-employed individuals from India were surveyed regarding their perceptions of meditation and estate planning ***:The survey indicates that mediation positively influences the estate planning decisions while individuals who practice meditation have greater preferences for estate planning compared with those who do *** findings suggest that individual assets,family size,and education positively influence the estate planning decisions of ***:Reported meditation,individual assets,family size,location,education,and gender are positively correlated with the estate planning decisions of Indians.

关键词： Meditation Estate planning Assets Income India

Imatinib-induced fatal acute liver failure

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World Journal of Gastroenterology 2007年第48期13卷 6608-6611页

作者： Ezequiel Ridruejo Roberto Cacchione Alejandra G Villamil Sebastián Marciano Adrián C Gadano Oscar G mandó Hepatology Section Hematology Section Department of Medicine Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" CEMIC Buenos Aires Argentina Liver Unit Hospital Italiano de Buenos Aires Buenos Aires Argentina

Imatinib mesylate is a drug that has been approved for treatment of chronic myeloid leukemia (CML) in blast crisis, accelerated or chronic phase, and also for advanced gastrointestinal stromal tumors. Severe hepatic toxicity and three deaths from hepatic failure have been reported. We report the case of a 51-year-old woman who was admitted to our institution with severe acute hepatitis. She was diagnosed with CML and began treatment with imatinib mesylate at a dose of 400 mg/d. Five months after beginning treatment, she developed severe hepatitis associated with coagulopathy, and was admitted to our institution. She had been consuming acetaminophen 500-1000 mg/d after the onset of symptoms. She had a progressive increase in bilirubin level and a marked decrease of clotting factor Ⅴ. Five days after admission, grade Ⅱ encephalopathy developed and she was referred for liver transplantation. Her clinical condition progressively deteriorated, and 48 h after being referred for transplantation she suffered a cardiac arrest and died. This report adds concern about the possibility of imatinib-mesylate-induced hepatotoxicity and liver failure, particularly in the case of concomitant use with acetaminophen. Liver function tests should be carefully monitored during treatment and, with the appearance of any elevation of liver function tests, treatment should be discontinued.

关键词： Imatinib mesylate Hepatotoxicity Acute liver failure Liver transplantation

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分形及迭代理论的复兴

数学译林 1992年第3期11卷 231-238页

作者： mand.,BB 井竹君

Postpartum Family Planning at the Timbuktu Hospital in Mali

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Total Electron Content Diurnal and Seasonal Variations and Response to Solar Events at Koudougou Station in Burkina Faso

Open Journal of Obstetrics and Gynecology（妇产科期刊） 2024年第7期 1074页

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International Journal of Geosciences 2023年第9期14卷 827-839页

作者： Yacouba Sawadogo M’Bi Kaboré Somaïla Koala Arouna mandé Jean Louis Zerbo Laboratoire de Matériaux d’Héliophysique et Environnement (La.M.H.E) Université Nazi BONI Bobo-Dioulasso Burkina Faso

In this paper, we studied the seasonal behavior of the total electron content (TEC) during a part of solar cycle 24 ascending, maximum and decreasing phases at Koudougou station (Latitude: 12°15'09"n Longitude: 2°21'45"W). Response of TEC to solar recurrent events is presented. The highest values of the TEC in 2014, 2015 and 2016 were recorded on March and October, while in 2013 they were recorded on April and november, corresponding to equinox months. This observation shows that TEC values at the equinoxes are higher than those of solstices. Moreover, the monthly TEC varies in phase with the sunspots number showing a linear dependence of the TEC on solar activity. The ionospheric electron contents are generally very low both before noon and during the night, but quite high at noon and after noon. This pattern of TEC variation is due to the fluctuation of incident solar radiation on the Earth’s equatorial ionosphere. During quiet periods, the number of free electrons generated is lower than that generated during recurrent periods, which shows a positive contribution of recurrent activity to the level of the TEC. Investigations have also highlighted a winter anomaly and equinoctial asymmetry in TEC behavior at Koudougou station.

关键词： Total Electron Content (TEC) Recurrent Activity Quiet Activity Seasonal Variation

Long-term survival following radiofrequency ablation of colorectal liver metastases: A retrospective study

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World Journal of Gastrointestinal Surgery 2015年第3期7卷 33-38页

作者： Simeon niyi Babawale Thomas mandФe Jensen Jens BrФndum FrФkjr Department of Radiology Aalborg University Hospital Department of Clinical Medicine Aalborg University

AIM: To retrospectively evaluate the long-term survivalof patients that received radiofrequency ablation(RFA) therapies of colorectal liver metastases. METHODS: In 2005 to 2008, RFA of 105 colorectal liver metastases(CRLM) were performed on 49 patients in our institution. The liver metastases were evaluated, both before and after ablation therapies, with contrast enhanced computerised tomography and contrast enhanced ultrasonography. Histological evidence of malignant liver metastases was obtained in the few instances where contrast enhanced ultrasonography gave equivocal results. Accesses to the CRLM were guided ultrasonically in all patients. The data obtained from records of these ablations were retrospectively analysed and survival data were compared with existing studies in the ***: 1-, 2-, 3-, 4- and 5-year survival rates, when no stringent selection criteria were applied, were 92%, 65%, 51%, 41% and 29% respectively. To explore the impact of the number and size of CRLM on patients' survival, an exclusion of 13 patients(26.5%) with number of CRLM ≥ 5 and tumour size ≥ 40 mm resulted in 1-, 2-, 3-, 4- and 5-year survival rates improving to 94%, 69%, 53%, 42% and 31% respectively. It is of note that 9 of 49 patients developed extra-hepatic metastases, not visible or seen on pretreatment scans, just after RFA treatment. These patients had poorer survival. The development of extra-hepatic metastases in nearly 20% of the patients included in our study can partly account for modestly lower survival rates as compared with earlier studies in the ***: Our study underscores the fact that optimum patients' selection before embarking on RFA treatment is vitally important to achieving a superior outcome.

关键词： Colorectal cancer Liver metastasis Radiofrequency ablation Long-term survival Ablation success

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分维几何：含义及应用

科学技术动态 1990年第2期 40-42页

作者： mand.,BB 王前