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Effect of different sol-gel synthesis processes on microstructural and morphological characteristics of hydroxyapatite-bioactive glass composite nanopowders

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Journal of Advanced Ceramics 2014年第3期3卷 207-214页

作者： Mohamadhassan TAHERIAN Ramin ROJAEE Mohammadhossein fathi Morteza TAMIZIFAR Department of Materials and Metallurgical Engineering Iran University of Science and Technology(IUST)Tehran 16866-13114Iran Biomaterials Research Group Department of Materials EngineeringIsfahan University of TechnologyIsfahan 84156-83111Iran Dental Materials Research Center Isfahan University of Medical SciencesIsfahanIran

The aim of this work was to study the influence of the different synthesis processes on microstructural and morphological characteristics and distribution of hydroxyapatite-bioactive glass(HAp-BG)composite nanopowders obtained by sol-gel ***-BG composite nanopowders with 20 wt%bioactive glass were prepared using a sol-gel method via four routes:(I)mixing the prepared HAp solution with BG solution before aging time;(II)mixing the prepared BG solution with the prepared HAp gel after gelation;(III)mixing the calcined BG nanopowders with the prepared HAp solution;and(IV)mixing the two prepared calcined nanopowders by mechanochemical *** prepared nanopowders were evaluated and studied by X-ray diffraction(XRD),scanning electron microscopy(SEM),energy dispersive X-ray spectrometer(EDS),Fourier transform infrared(FTIR),transmission electron diffraction(TEM)and Brunauer-Emmet-Teller(BET)method to investigate the phase structure,microstructure and morphology,functional groups,and the size and distribution of *** indicated that morphology,crystallinity,crystallite size and specific surface area(SSA)of the powders are highly correspondent to the process and type of synthesis *** findings suggest that the modified sol-gel derived HAp-BG composite nanopowders are expected to efficiently provide a possibility to produce a good candidate to use for fabrication of a bulk nanostructured HAp-BG composite for bone tissue engineering.

关键词： hydroxyapatite(HAp) bioactive glass(BG) composite nanopowders sol-gel

Experimental study of the velocity of density currents in convergent and divergent channels

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International Journal of Sediment Research 2013年第2期28卷 254-259页

作者： Hasan Torabi POUDEH Samad EMAMGHOLIZADEH Manoocher fathi-MOGHADAM Department of Water Engineering Lorestan of University Department of Water and Soil Engineering Shahrood University of Technology Department of Hydraulic Structures Shahid Chamran University

The head velocity of the density current in the convergent and divergent channel is a key parameter for evaluating the extent to which suspended material travels,and for determining the type and distribution of sediment in the water *** study experimentally evaluated the effects of the reach degree of convergence and divergence on the head velocity of the density *** were conducted in the flume with 6.0 m long,0.72 m width and 0.6 m *** head velocity was measured at three convergent degrees(-8°;-12°;-26°),at three divergent degrees(8°;12°;26°) and two slopes(0.009,0.016) for various *** measured head velocity of the density current is compared with the head velocity of the density current in the constant cross section channel. Based on non-dimensional and statistical analysis,relations as linear multiple regression offered for prediction head velocity of the density current in the convergent,divergent and constant cross section *** the results of this research show that for the same slope and discharge,the head velocity of the density current in the convergent and divergent channel are greater and less than the head velocity of the constant cross section, respectively.

关键词： Density current Divergent and convergent channel Reservoir Sediment

Immunohistochemical expression of matrix metalloproteinase-9 and 13 in oral squamous cell carcinoma and their role in predicting lymph node metastasis

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World Journal of Methodology 2025年第2期15卷 108-116页

作者： Bhari Sharanesha Manjunatha Keshav T Handge Vandana Sandeep Shah Yasser Eid al-Thobaiti Deepak Gowda Sadashivappa Pateel Department of Basic Oral Medicine and allied Dental Sciences Taif UniversityAt`Taif 26571MakkahSaudi Arabia Department of Oral and Maxillofacial Pathology Dr.Vasantrao Pawar Medical CollegeHospital and Research CentreNashik 423101MaharashtraIndia Department of Oral Pathology and Microbiology KM Shah Dental College and HospitalSumandeep VidyapeethVadodara 391760GujaratIndia Department of Oral and Maxillofacial Surgery and Diagnostic Sciences Faculty of DentistryTaif UniversityAl-Haweiah 26571 MakkahSaudi Arabia Department of Oral Pathology and Microbiology Faculty of DentistryMAHSA UniversitySelangor 42610Malaysia

BACKGROUND One of the main characteristics of oral squamous cell carcinoma(OSCC)is that it metastasizes to cervical lymph nodes frequently with a high degree of local invasiveness.A primary feature of malignant tumors is their penetration of neighboring tissues,such as lymphatic and blood arteries,due to the tumor cells'capacity to break down the extracellular matrix(ECM).Matrix metalloproteinases(MMPs)constitute a family of proteolytic enzymes that facilitate tissue remo-deling and the degradation of the ***-9 and MMP-13 belong to the group of extracellular matrix degrading enzymes and their expression has been studied in OSCC because of their specific ***-13,a collagenase family member,is thought to play an essential role in the MMP activation cascade by breaking down the fibrillar collagens,whereas MMP-9 is thought to accelerate the growth of *** MMP-13 expression has been associated with tumor behavior and patient prognosis in a number of malignant *** authors wish to thank Jadhav KB for his valuable opinion during the preparation of the manuscript.

关键词： Matrix metalloproteinases Oral squamous cell carcinoma Tumor staging Immunohistochemistry Invasion Lymph node metastasis TNM stage

Experimental study of the velocity of density currents in convergent and divergent channels

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International Journal of Sediment Research 2014年第4期29卷 518-523页

作者： Hasan Torabi POUDEH Samad EMAMGHOLIZADEH Manoocher fathi-MOGHADAM Department of Water Engineering Lorestan of University Department of Water and Soil Engineering University of Shahrood Department of Hydraulic Structures Shahid Chamran University

The head velocity of the density current in the convergent and divergent channel is a key parameter for evaluating the extent to which suspended material travels,and for determining the type and distribution of sediment in the water *** study experimentally evaluated the effects of the reach degree of convergence and divergence on the head velocity of the density *** were conducted in the flume with 6.0 m long,0.72 m width and 0.6 m *** head velocity was measured at three convergent degrees(-8°;-12°;-26°),at three divergent degrees(8°;12°;26°) and two slopes(0.009,0.016) for various *** measured head velocity of the density current is compared with the head velocity of the density current in the constant cross section *** on non-dimensional and statistical analysis,relations as linear multiple regression are offered for predicting head velocity of the density current in the convergent,divergent and constant cross section *** the results of this research show that for the same slope and discharge,the head velocity of the density current in the convergent and divergent channel are greater and less than the head velocity of the constant cross section,respectively.

关键词： Density current Divergent and convergent channel Reservoir Sediment

Decoding molecular mechanisms:brain aging and alzheimer's disease

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Neural Regeneration Research 2025年第8期20卷 2279-2299页

作者： Mahnoor Hayat Rafay ali Syed Hammad Qaiser Mohammad Uzair Khalid al-Regaiey Roaa Khallaf Lubna Abdullah Mohammed albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir Atta-ur-Rahman School of Applied Biosciences(ASAB) National University of Sciences and Technology(NUST)IslamabadPakistan Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan Department of Biological Sciences Faculty of Basic&Applied SciencesInternational Islamic University Islamabad(IIUI)IslamabadPakistan Department of Bioengineering King Fahd University of Petroleum and MineralsDhahranSaudi Arabia Department of Physiology College of MedicineKing Saud UniversityRiyadhSaudi Arabia Department of Neurology Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Mental Health Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Biosciences Commission on Science and Technology for Sustainable Development in the South(COMSATS University)IslamabadPakistan Department of Psychiatry The First Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Mental Health Institute of Hebei Medical University ShijiazhuangHebei ProvinceChina Department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA Neuroscience Center King Fahad Specialist Hospital DammamDammamSaudi Arabia

The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for *** aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as alzheimer's *** these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging *** these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect *** review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly alzheimer's disease.

关键词： alzheimer’s disease brain aging cognitive health dementia molecular mechanisms neuronal activity neuroplasticity neurotransmission

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Peritoneal carcinomatosis of gastrointestinal tumors: Where are we now?

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World Journal of Gastroenterology 2014年第39期20卷 14371-14380页

作者： Cem Terzi Naciye Cigdem Arslan aras Emre Canda Department of Colorectal and Pelvic Surgery Dokuz Eylul University School of MedicineInciraltIzmir 35340Turkey

The peritoneal stromal tissue which provides a rich source of growth factors and chemokines is a favorable environment for tumor proliferation. The pathophysiological mechanism of peritoneal carcinomatosis is an individual sequence consisting of genetic and environmental factors and remains controversial. The natural history of the disease reveals a poor median prognosis of approximately 6 mo; however aggressive surgery and multimodal treatment options can improve oncologic outcomes. Considering peritoneal carcinomatosis as though it is a locoregional disease but not a metastatic process, cytoreductive surgery and and intraperitoneal chemotherapy has been a curative option during recent years. Cytoreductive surgery implies a series of visceral resections and peritonectomy procedures. although the aim of cytoreductive surgery is to eliminate all macroscopic disease, viable tumor cells may remain in the peritoneal cavity. At that point, intraperitoneal chemotherapy can extend the macroscopic disease elimination to microscopic disease elimination. The successful treatment of peritoneal carcinomatosis requires a comprehensive management plan including proper patient selection, complete resection of all visible disease, perioperative intraperitoneal chemotherapy and postoperative systemic chemotherapy. Surgical and oncologic outcomes are strictly associated with extent of the tumor, completeness of cytoreduction and patientrelated factors as well as multidisciplinary management and experience of the surgical team. In this review, pathophysiology and current management of peritoneal carcinomatosis originating from gastrointestinal tumors are discussed according to the latest literature.

关键词： Peritoneal carcinomatosis Gastrointestinal tumors Cytoreductive surgery Intraperitoneal chemotherapy Oncologic surgery

Effect of metal oxide arrester on the chaotic oscillations in the voltage transformer with nonlinear core loss model using chaos theory

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Chinese Physics B 2014年第1期23卷 480-488页

作者： Hamid Reza Abbasi Ahmad Gholami Seyyed Hamid fathi Ataollah Abbasi Iran University of Science & Technology Electrical & Electronic Engineering Department Narmak *** Tehran Iran Amirkabir University Electrical Engineering Department Tehran 64540 Iran

In this paper, controlling chaos when chaotic ferroresonant oscillations occur in a voltage transformer with nonlin- ear core loss model is performed. The effect of a parallel metal oxide surge arrester on the ferroresonance oscillations of voltage transformers is studied. The metal oxide arrester （MOA） is found to be effective in reducing ferroresonance chaotic oscillations. also the multiple scales method is used to analyze the chaotic behavior and different types of fixed points in ferroresonance of voltage transformers considering core loss. This phenomenon has nonlinear chaotic dynamics and includes sub-harmonic, quasi-periodic, and also chaotic oscillations. In this paper, the chaotic behavior and various ferroresonant oscillation modes of the voltage transformer is studied. This phenomenon consists of different types of bifur- cations such as period doubling bifurcation （PDB）, saddle node bifurcation （SNB）, Hopf bifurcation （HB）, and chaos. The dynamic analysis of ferroresonant circuit is based on bifurcation theory. The bifurcation and phase plane diagrams are il- lustrated using a continuous method and linear and nonlinear models of core loss. To analyze ferroresonance phenomenon, the Lyapunov exponents are calculated via the multiple scales method to obtain Feigenbaum numbers. The bifurcation diagrams illustrate the variation of the control parameter. Therefore, the chaos is created and increased in the system.

关键词： ferroresonance chaos theory metal oxide arrester Lyapunov exponent

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Microcapillary cell extrusion deposition with picolitre dispensing resolution

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Bio-Design and Manufacturing 2023年第1期6卷 1-11页

作者： Saeed fathi Iek Man Lei Yang Cao Yan Yan Shery Huang Department of Engineering University of CambridgeCambridgeUK The Nanoscience Centre University of CambridgeCambridgeUK

Extrusion-based cell deposition has become a prominent technique for expanding bioprinting ***,the associated print resolution in the order of nanolitre or above has been a limiting *** demand for improving print resolution towards the scale of a single cell has driven the development of precision nozzle extrusion,although the benefits gained remain ***,aided by in situ imaging,we investigated the dynamics of cell organisation through an extrusion-based microcapillary tip with picolitre precision through in-air or immersion *** microcapillary extrusion setup,termed‘Picodis’,was demonstrated by generating droplets of colouring inks immersed in an immiscible ***,using 3T3 fibroblast cells as an experimental model,we demonstrated the deposition of cell suspension,and pre-aggregated cell ***,the dynamic organisation of cells within the microcapillary tip was described,along with cell ejection and deposition upon exiting the tip *** vision-assisted approach revealed that when dispersed in a culture medium,the movements of cells were distinctive based on the flow profiles and were purely driven by laminar fluid flow within a narrow *** primary process limitations were cell sedimentation,aggregation and compaction,along with trapped air *** use of picolitre-level resolution microcapillary extrusion,although it provides some level of control for a small number of cells,does not necessarily offer a reliable method when a specified number of cells are *** study provides insights into the process limitations of high-resolution cell ink extrusion,which may be useful for optimising biofabrication processes of cell-laden constructs for biomedical research.

关键词： Microcapillary cell printing Resolution dispensing Cell sedimentation Single cell

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A novel fuzzy approach to gas pipeline risk assessment under infuence of ground movement

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International Journal of Coal Science & Technology 2022年第4期9卷 82-92页

作者： Agnieszka Malinowska Ximin Cui Ebrahim fathi Salmi Ryszard Hejmanowski AGH University of Science and Technology Al.Mickiewicza 3030059 CracowPoland China University of Mining and Technology(Beijing) D11 Xueyuan RoadBeijing 100083China Hard Rock Mining CSIRO and Mining3QCATPullenvaleQLD 4069Australia

The gas transport infrastructure is frequently localized in areas subjected to anthropogenic movements and *** potential impact of the ground movements on the gas pipeline in the aspect of its damage can be properly assessed *** predicting strains,taking into account the causes of terrain *** the other hand,the hazard is also related to technological factors like design of the *** presented method is based on artifcial intelligence methods allowing for evaluation of probability of failure risk in gas supply pipeline *** Mamdani fuzzy inference was used in this *** of variables characterizing the resistance of the gas pipeline and predicted continuous deformations of ground surface were accounted for in the model by using triangular-shaped membership *** on the surface deformations and gas pipeline resistance and the inference model one can make prediction when the gas pipeline is *** were estimated two the most hazarded parts for two *** proved that the proposed model can contribute to the protection,costoptimization of the designed pipelines and to the repairs of the existing gas pipelines.

关键词： Fuzzy logic Gas pipeline GIS Horizontal strain Land subsidence Risk management