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Asian Pacific Journal of Tropical Medicine 2009年第3期2卷 74-76页

作者： Gyuse AN Udonwa ne Okokon IB Ibanga I Ogbonna UK Department of Family Medicine University of Calabar Teaching HospitalCalabarCross River StateNigeria Department of Haematology University of Calabar Teaching HospitalCalabarCross River StateNigeria

Objective:This study aimed to determine the prevalence of Hepatitis B antigen among newly employed staff in a Tertiary Hospital in South-South ***:The medical records of a total of 238 newly employed members of staff of the University of Calabar Teaching Hospital between 2000 and 2006 were *** socio-demographic data and Hepatitis B Surface Antigen(HBSAg) results were ***:The overall prevalence of Hepatitis B Surface Antiginaemia was found to be 5.04%.The prevalence was 7.30%in males and statistically significant compared to 3.50%in ***:There is a reasonably high prevalence of HBSAg among adults prior to employment into Health Care *** poses a danger to clients seeking care in these health care facilities and other health care *** Institutions must have clear policies on engagement of new staff relating to such communicable diseases based on existing Nigerian labour laws including the Workman Compensation *** must also implement policies on universal precautions to safeguard the health workers and clients in their *** enlightenment on the National Program on Immunization(NPI) must be intensified as a strategy to reduce the prevalence of HBSAg and its attendant consequences.

关键词： Hepatitis B Antigen newly employed

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Edouard Manet

Edouard Manet

Enhancing optical absorption in visible light of ZnO co-doped with europium and promethium by first-principles study through modified Becke and Johnson potential scheme

作者： Gilles ne?ret [translation Chris Miller].

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Journal of Rare Earths 2019年第4期37卷 416-421页

作者： A.G.El Hachimi M.L.Ould ne A.El Yousfi A.Benyoussef A.El Kenz Laboratory of Condensed Matter and Interdisciplinary Sciences (LaMCScI) Associé Au CNRST (URAC 12) Département de Physique B.P.1014 Faculté des SciencesUniversité Mohammed V Hassan Ⅱ Academy of Science and Technology

By using first-principles calculations we studied the electronic, optical and magnetic properties of ZnO co-doped with Eu and Pm. In this calculation, we used Wien2 k code based on full potential linearized augmented plane waves(FP-LAPW) method with the modified Becke-Johnson(mBJ) approximation. This correction gives good band gap compared to experimental band gap. The introduction of Eu and Pm codoping leads to an increase in the band gap. Electrons can transit easily from the valence band to the conduction band, which results in an enhancement of visible light absorption in a wider absorption range. Absorption spectra reach a high value in visible and infrared light regions. With the significance of the obtained results, the studied compounds may potentially find spintronic and optoelectronic applications.

关键词： Zinc oxide Rare earth Density functional theory Modified Becke-Johnson Magnetic properties Spintronics

An Approach for Using of Poly Glycolic Acid (PGA) in Reference Standard Dosimetry: PGA/ESR Dosimetry System Response Curve and Post Irradiation Stability

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World Journal of Nuclear Science and Technology 2012年第3期2卷 73-79页

作者： arbi Mejri Haikel Jelassi Khaled Farah Ahmad Hichem Hamzaoui Hichem Eleuch Departments of Physics and Astronomy Institute for Quantum Science and Engineering Texas A & M University College Station Texas USA Ionizing Radiation Dosimetry Laboratory National Center for Nuclear Sciences and TechnologiesTunis Tunisia National Institute of Scientific and Technical Research Tunisia Research Unit: Control and Development of Nuclear Technology for Peaceful Uses National Center for Nuclear Sciences and Technologies Tunis Tunisia

Reference Standard Dosimeters are used to calibrate radiation environments and routine dosimeters. It can also be used in routine dosimetry applications for radiation processing where higher quality dosimetry measurements are required. Electron Spin Resonance (ESR) is a well-established Reference Standard Dosimetry system in industrial applications of ionising radiation, and its use is also proposed in radiation therapy and accident dosimetry. In the present experimental work, PGA solid state dosimeter (SSD) has been investigated using ESR spectroscopy to study the gamma radiation response of this material and to evaluate its dosimetric characteristics: dose response, room temperature fading, heat treatment effect during post-irradiation storage. Results obtained up to now confirm that PGA seems to be suitable material for ESR dosimetry applications.

关键词： Dosimetry Solid State Dosimeter (SSD) Poly Glycolic Acid (PGA) Electron Spin Resonance (ESR) Reference Standard Dosimetery Post-Irradiation Thermal Treatments Fading Behaviour

Unraveling the morphological patterns of a subantarctic eelpout:a geometric morphometric approach

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Integrative Zoology 2023年第2期18卷 372-384页

作者： Fernanda S.ORREGO Mathias HÜne Hugo A.BENÍTEZ Mauricio F.LANDAETA Laboratorio de Ictiología e Interacciones Biofísicas(LABITI) Instituto de BiologíaFacultad de CienciasUniversidad de ValparaísoValparaísoChile Centro de Investigación para la Conservación de los Ecosistemas Australes(ICEA) Punta ArenasChile Laboratorio de Ecología y Morfometría Evolutiva Centro de Investigación de Estudios Avanzados del MauleUniversidad Católica del MauleTalcaChile Centro de Observación Marino para Estudios de Riesgos del Ambiente Costero(COSTA-R) Universidad de ValparaísoViña del MarChile Millennium Nucleus for Ecology and Conservation of Temperate Mesophotic Reef Ecosystems(NUTME) Millennium Institute Biodiversity of Antarctic and Subantarctic Ecosystems(BASE) SantiagoChile

Phenotypic variation in organisms depends on the genotype and the environmental constraints of the habitat that they ***,for marine species inhabiting contrasting aquatic conditions,it is expected toﬁnd covari-ation between the shape and its spatial *** studied the morphology of the head and cephalic sensory canals of the eelpout Austrolycus depressiceps(4.5–22.5 cm TL)across its latitudinal distribution in South Paciﬁc(45°S–55°S).Geometric morphometric analyses show that the shape varied from individuals with larger snout and an extended suborbital canal to individuals with shorter snouts and frontally compressed suborbital *** was size variation across the sampled populations,but that size does not have a clear latitudinal *** 8%of the shape variation relates to this size variation(allometry),represented by a decrease in the relative size of the eye,and a depression of the posterior margin of the *** were spatial differences in the shape of the head,but these differences were probably caused by allometric ***,2 of the canals of the cephalic lateralis pores and the head shape showed modularity in its *** study shows that the morphology of marineﬁsh with a shallow distribution varies across distances of hundreds of kilometers(i.e.,phenotypic modulation).

关键词： Austrolycus depressiceps geometric morphometrics morphology phenotype spatial distribution

Advanced gastric cancer achieving major pathologic regression after chemoimmunotherapy combined with hypofractionated radiotherapy: A case report

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World Journal of Gastrointestinal Oncology 2023年第6期15卷 1096-1104页

作者： Meng-Long Zhou Ruo-ne Xu Cong Tan Zhen Zhang Jue-Feng Wan Department of Radiation Oncology Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Shanghai Key Laboratory of Radiation Oncology Fudan UniversityShanghai 200032China Department of Pathology Fudan University Shanghai Cancer CenterShanghai 200032China

BACKGROUND Currently,chemotherapy combined with immunotherapy is the established firstline standard treatment for advanced gastric cancer(GC).In addition,the combination of radiotherapy and immunotherapy is considered a promising treatment *** SUMMARY In this report,we present a case of achieving nearly complete remission of highly advanced GC with comprehensive therapies.A 67-year-old male patient was referred to the hospital because he presented with dyspepsia and melena for several *** on fluorodeoxyglucose positron emission tomography/computed tomography(FDG PET/CT),endoscopic examination and abdominal CT,he was diagnosed with GC with a massive lesion and two distant metastatic *** patient received mFOLFOX6 regimen chemotherapy,nivolumab and a short course of hypofractionated radiotherapy(4 Gy×6 fractions)targeting the primary *** the completion of these therapies,the tumor and the metastatic lesions showed a partial *** having this case discussed by a multidisciplinary team,the patient underwent surgery,including total gastrectomy and D2 lymph node *** pathology showed that major pathological regression of the primary lesion was *** therapy started four weeks after surgery,and examination was performed every three *** surgery,the patient has been stable and healthy with no evidence of *** The combination of radiotherapy and immunotherapy for GC is worthy of further exploration.

关键词： Gastric cancer Oligometastasis Immunotherapy Hypofractionated radiotherapy Gastrectomy Case report

Genomic prediction of fruit texture and training population optimization towards the application of genomic selection in apple

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Horticulture Research 2020年第1期7卷 889-902页

作者： Morgane Roth Hélène Muranty Mario Di Guardo Walter Guerra Andrea Patocchi Fabrizio Costa Plant Breeding Research Division AgroscopeWädenswilZurichSwitzerland IRHS INRAEAgrocampus-OuestUniversitéd’AngersSFR 4207 QuaSaVBeaucouzéFrance Department of Genomics and Biology of Fruit Crops Research and Innovation CentreFondazione Edmund Mach(FEM)Via E.Mach 138010 San Michele all’AdigeItaly Department of Agriculture Food and Environment(Di3A)University of CataniaCataniaItaly Research Centre Laimburg Laimburg 639040 AuerItaly Center Agriculture Food Environment University of TrentoVia Mach 138010 San Michele all’AdigeItaly Present address:GAFL INRAE84140 MontfavetFrance

Texture is a complex trait and a major component of fruit quality in *** the major effect of MdPG1,a gene controlling firmness,has already been exploited in elite cultivars,the genetic basis of crispness remains poorly *** further improve fruit texture,harnessing loci with minor effects via genomic selection is therefore *** this study,we measured acoustic and mechanical features in 537 genotypes to dissect the firmness and crispness components of fruit *** of across-year phenotypic values for these components were calculated using a model calibrated with 8,294 SNP *** best prediction accuracies following cross-validations within the training set of 259 genotypes were obtained for the acoustic linear distance(0.64).Predictions for biparental families using the entire training set varied from low to high accuracy,depending on the family *** adding siblings or half-siblings into the training set did not clearly improve predictions,we performed an optimization of the training set size and composition for each validation *** allowed us to increase prediction accuracies by 0.17 on average,with a maximal accuracy of 0.81 when predicting firmness in the‘Gala’×‘Pink Lady’*** results therefore identified key genetic parameters to consider when deploying genomic selection for texture in *** particular,we advise to rely on a large training population,with high phenotypic variability from which a‘tailored training population’can be extracted using a priori information on genetic relatedness,in order to predict a specific target population.

关键词： prediction optimization fir

Liver transplantation for alcoholic liver disease: Lessons learned and unresolved issues

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World Journal of Gastroenterology 2015年第39期21卷 10994-11002页

作者： José Ursic-Bedoya Stéphanie Faure Hélène Donnadieu-Rigole Georges-Philippe Pageaux Liver Transplantation Unit Digestive Department Saint Eloi University Hospital University of Montpellier Addictology Department Saint Eloi University Hospital University of Montpellier

The use of liver transplantation(LT) as a treatment for alcoholic liver disease(ALD) has been highly controversial since the beginning. The ever increasing shortage of organs has accentuated the low priority given to patients suffering from ALD, which is considered a "self-inflicted" condition. However, by improving the long-term survival rates, making them similar to those from other indications, and recognizing that alcoholism is a primary disease, ALD has become one of the most common indications for LT in Europe and North America, a situation thought unfathomable thirty years ago. Unfortunately, there are still many issues with the use of this procedure for ALD. There are significant relapse rates, and the consequences of excessive drinking after LT range from asymptomatic biochemical and histological abnormalities to graft failure and death. A minimum three-month period of sobriety is required for an improvement in liver function, thus making LT unnecessary, and to demonstrate the patient's commitment to the project, even though a longer abstinence period does not guarantee lower relapse rates after LT. Recent data have shown that LT is also effective for severe alcoholic hepatitis when the patient is unresponsive to corticosteroids therapy, with low relapse rates in highly selected patients, although these results must be confirmed before LT becomes a standard procedure in this setting. Finally, LT for ALD is accompanied by an increased risk of de novo solid organ cancer, skin cancer, and lymphoproliferative disorders, which has a large impact on the survival rates.

关键词： Liver transplantation Alcoholic liver disease Cirr

High voltage electrical treatments can eco-efficiently promote the production of high added value peptides during chymotryptic hydrolysis of β-lactoglobulin

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Food Bioscience 2022年第3期47卷 197-210页

作者： Rock-Seth Agoua Laurent Bazinet Jacinthe Thibodeau Eugène Vorobiev Nabil Grimi Sergey Mikhaylin Institute of Nutrition and Functional Foods (INAF) Dairy Research Center (STELA)Food Science DepartmentUniversité LavalQuébecQCCanada Laboratory of Food Sustainability (EcoFoodLab) Food Science DepartmentUniversité LavalQuébecQCCanada Laboratoire de Transformation Alimentaire et Procédés Électro-Membranaires (LTAPEM) Food Science DepartmentUniversité LavalQuébecQCCanada University of Technology of Compiègne Laboratory of Agro-industrial technologiesCompiègneFrance

Chymotryptic hydrolysis of β-lactoglobulin (β-lg) leads to the release of a wide range of biofunctional ***,the proteolysis of native β-lg is limited due to its compact globular structure,thus ending with low yields of *** our previous study showed that eco-efficient High Voltage Electric Treatments (HVET),namely Pulsed Electric Fields (PEF) and Electric Arc (ARC),of β-lg substantially improved its enzymatic hydrolysis,no information regarding the nature of released peptides is available up to ***,the time-dependent release of peptides and the dynamics of this release were discussed in the current *** analysis of the final hydrolysates showed that chymotrypsinolysis of HVET samples released 19% more peptides with higher concentration than the native and preheated ***,1-min HVET were found to be more efficient than 10-min ones as they led to the release of bioactive peptides (even without chymotrypsin) with higher eco-efficiency scores.

关键词： β-lactoglobulin Peptides High-voltage electrical treatments Eco-efficiency Chymotrypsin Hydrolysis.

Assessment of the carbon abatement and removal opportunities of the Arabian Gulf Countries

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Clean Energy 2021年第2期5卷 340-353页

作者： Abdulrahman Alatiq Wail Aljedani Abdullah Abussaud Omar Algarni Hélène Pilorgé Jennifer Wilcox Department of Chemical Engineering Worcester Polytechnic InstituteGoddard Hall100 Institute RoadWorcesterMA 01609USA Department of Chemical and Biomolecular Engineering University of Pennsylvania220 S.33rd StreetPhiladelphiaPA 19104USA

The Arabian Gulf Countries(AGC)are strongly reliant on the economic export of fossil fuels,while being vulnerable to climate change that is resulting in temperature increase,air pollution and sea-level rise,and threatening the health of the population and *** agreement with the Paris Accords,most of the AGC have published short-term goals to reduce their carbon emissions in the coming *** relation to these goals,this study explores the potential CO_(2)reduction,avoidance and removal in the region,by comparing a business-as-usual(BAU)scenario to three decarbonization scenarios for the power *** 2018,the total greenhouse gas(GHG)emissions in the AGC were~1333 MtCO_(2)/yr and are expected to rise to 1568 MtCO_(2)/yr in 2030 following a BAU scenario,which is likely to be reduced to 1522 MtCO_(2)/yr in 2030 by following the countries’*** issued plans for the coming decades that focus on increasing the share of renewable energy in their grid *** three decarbonization scenarios presented in this study focus on supply-side technological *** retirement of the oldest natural-gas and oil power plants could lead to a total emissions reduction of~75 MtCO_(2)/yr,without accounting for the embodied carbon emissions associated with renewable *** addition,the implementation of point-source capture at power plants expected to retire in>10 years’time could avoid emissions of~240 MtCO_(2)/yr,provided the CO_(2)is permanently sequestered in appropriate geological *** region also shows high-quality solar resources and large CO_(2)-storage potential that could couple to direct air-capture plants to offset difficult-to-avoid *** last scenario has the potential to ultimately result in net negative emissions.

关键词： carbon capture CCUS direct air capture