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Chinese Journal of Chemistry 2023年第17期41卷 2159-2178页

作者： Chen Zhang Linli Xu Wai-yeung wong Departmentof Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHung HomHong Kongchina

omprehensive Summary,Polymetallaynes are a promising branch of metallopolymers,in which the introduction of metal building blocks to organic conjugated backbones leads to their unique skeletons and versatile ***,the chemical structures,geometric configurations and functional properties in these organometallic systems can be adjusted flexibly by the appropriate selection of metal centers,auxiliary ligands,or bridging *** recent years,both one-dimensional and two-dimensional polymetallaynes have attracted considerable attention owing to their excellent electronic,optical and magnetic ***,the studies on molecular metallaynes provide substantial insights for the exploration of the structure-property-activity relationships in these organometallic acetylide-containing *** recent research progress of polymeric and molecular metallaynes containing platinum,mercury and gold is discussed in this article.A series of functional properties have been realized in these acetylide-containing compounds by the rational structural design and refined synthetic strategies,leading to their emerging applications including energy conversion,nonlinear optics,data storage and memory,as well as chemo/biosensing.

关键词： Polymetallayne Molecular metallayne Metallated graphyne Platinum Mercury Gold

Prospective study of Centurion~？ versus Infiniti~？ phacoemulsification systems： surgical and visual outcomes

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International Journal of Ophthalmology(English edition) 2017年第11期10卷 1698-1702页

作者： Lawrence J.Oh Chu Luan Nguyen Eugene wong Samuel S.y.Wang Ian C.Francis University of New South Wales Sydney 2000 Australia Department of Ophthalmology Prince of Wales Hospital Sydney 2031 Australia Chatswood Private Hospital Chatswood Sydney 2067 Australia

AIM： To evaluate surgical outcomes（SOs） and visual outcomes（VOs） in cataract surgery comparing the Centurion？ phacoemulsification system（CPS） with the Infiniti？ phacoemulsification system（IPS）.METHODS： Prospective, consecutive study in a singlesite private practice. Totally 412 patients undergoing cataract surgery with either the CPS using the 30-degree balanced？ tip（n=207） or the IPS using the 30-degree kelman？ tip（n=205）. Intraoperative and postoperative outcomes were documented prospectively up to one month follow-up. Nuclear sclerosis（NS） grade, cumulated dissipated energy（CDE）, preoperative corrected distance visual acuity（CDVA）, and CDVA at one month were recorded. RESULTS： CDE was 13.50% less in the whole CPS compared with the whole IPS subcohort. In eyes with NS grade III or greater, CDE was 28.87% less with CPS（n=70） compared with IPS（n=44）（P=0.010）. Surgical complications were not statistically different between the two subcohorts（P=0.083）, but in the one case of vitreous loss using the CPS, CDVA of 6/4 was achieved at one month. The mean CDVAs（VOs） at one month for NS grade III and above cataracts were-0.17 log MAR（6/4.5） in the CPS and-0.15 log MAR（6/4.5） in the IPS subcohort respectively（P=0.033）.CONCLUSION： CDE is 28.87% less, and VOs are significantly improved, in denser cataracts in the CPS compared with the IPS. The authors recommend the CPS for cases with denser nuclei.

关键词： phacoemulsification Infiniti Centurion cumulated dissipated energy visual and surgical outcomes

Spatial orientation during eyes closed versus open in the dark: Are they the same?

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World Journal of Neuroscience 2012年第2期2卷 126-132页

作者： Raymond k. y. Chong Ben Gibson Scott Horton april Lee Jordan Mellinger kyoung-Hyun Lee Department of Physical Therapy Georgia Health Sciences University Augusta USA

We hypothesized that keeping one’s balance with eyes open in the dark is different and more difficult than eyes closed because the brain continues to process visual inputs in the dark when the eyes are open. On the other hand, when the eyes are closed, the visual system does not signal incongruent information with which the brain must compare the other sensory systems. A variety of cognitive (subtracting backwards by seven as quickly and accurately as possible) and support surface (fixed versus sway-referenced) conditions were used to probe the neural mechanisms underlying the sensory organization processes in healthy young adults. Peak-to-peak anteroposterior sway performance revealed two dissociated components of the treatment effects. The first component came from the visuospatial factor. Balance control during eye closure and eyes open in the dark were found to be similar but poorer than baseline condition (eyes open under typical lighting). The second component was the effect of task difficulty in which balance control in the sway-referenced condition was worse compared to fixed support during eye closure or eyes open in the dark. Analyses of the cognitive performance also revealed different underlying neural mechanisms of the experimental conditions. Subtraction speed under the fixed support surface condition was similar among all the conditions but was faster with eyes closed during the sway-referenced support surface condition. Accuracy was not affected among the visual and surface conditions. We conclude that sensory processing load with eyes closed is lower than eyes open in the dark, thereby allowing cognitive performance to proceed more efficiently. Performing a difficult subtraction task with eyes closed may afford a decrease in dual-task interference since similar brain areas, particularly the parietal region, are involved in both tasks. The results are discussed with reference to clinical application and spatial disorientation in aviation.

关键词： Attention Balance Computational Neuroscience Dual-Task Modular Theory Parietal Romberg Visuospatial

机器人在头颈外科中的应用--香港中文大学经验

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临床耳鼻咽喉头颈外科杂志 2018年第14期32卷 1056-1060页

作者：陈英权王维杨梁发雅黄晓明 Jason y k Chan Eddy W y wong 香港中文大学耳鼻咽喉头颈外科学系中山大学孙逸仙纪念医院耳鼻咽喉科 Department of Otorhinolaryngology Head and Neck SurgeryThe Chinese University of Hong Kong

目的:机器人手术目前已在头颈部多个区域得到了应用,本文探讨香港中文大学头颈外科机器人手术的经验。方法:回顾性分析2015年1月以来在香港中文大学耳鼻咽喉头颈外科开展的所有机器人头颈外科手术病例资料。结果:24例患者采用达芬奇S或... 详细信息

目的:机器人手术目前已在头颈部多个区域得到了应用,本文探讨香港中文大学头颈外科机器人手术的经验。方法:回顾性分析2015年1月以来在香港中文大学耳鼻咽喉头颈外科开展的所有机器人头颈外科手术病例资料。结果:24例患者采用达芬奇S或达芬奇Xi系统进行了手术,21例患者使用新型柔性机器人达芬奇SP系统行了手术。均无二次手术等严重不良事件。已经发表的达芬奇SP系统手术的7例患者早期结果表明,通过达芬奇SP系统可以到达鼻咽、口咽部、下咽部、喉部和咽后淋巴结完成手术,不需中途改变手术方式,没有发生与使用该系统有关的严重不良事件或不良事件。结论:通过我们在香港中文大学的经验,我们认为采用达芬奇机器人系统进行经口手术或经耳后入路颈部手术是安全有效的。

关键词：机器人头颈部手术经口机器人手术

Contributing to a Healthy Older Population of the Future: Investigating the Daily Walking Steps of Working Adults in Hong kong

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Journal of Biosciences and Medicines 2015年第9期3卷 22-31页

作者： Linda y. k. Lee Simon C. Lam S. L. wong Alisa k. P. wong Cheryl C. y. yeung Division of Nursing and Health Studies The Open University of Hong Kong Hong Kong China

Developing a healthy lifestyle during adulthood is one of the essential factors to prepare for healthy aging. This cross-sectional descriptive study investigated the daily walking steps of 893 working adults from nine occupation categories in Hong kong. Their daily walking steps were measured using a pedometer. Analysis of variance (ANOVA) was used to compare the difference in daily walking steps between participants in different occupation category. Chi-square test was used to compare the difference in proportion of working adults in each occupation category who walked and did not walk 10,000 steps per day. Results reveal that the participants in average walked 8661 steps per day. “Plant and machine operators and assemblers” and “clerks” were the two least active groups. Participants from the nine occupation categories demonstrated a significant difference in the number of daily walking steps. Post hoc analysis revealed a significant difference between “plant and machine operators and assemblers” and “service workers and shop sales workers” (p kers” (p ked and did not walk 10,000 steps per day. Owing to a large difference in number of participants in the nine occupation categories and other study limitations, further systematic investigation is indicated to confirm the study results. To summarize, working adults in Hong kong are only somewhat active. Identifying the factors that deter the working adults from walking and the ways to promote walking among working adults is necessary to prepare a healthy older population of the future.

关键词： Pedometer Physical Activity Walking Working Adults Hong kong

Role of C11-FDG dual-tracer PET-CT scan in metastatic screening of hepatocellular carcinoma-a cost-effectiveness analysis

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Hepatobiliary Surgery and Nutrition 2021年第3期10卷 301-307页

作者： kevin k.W.Chu Albert C.y.Chan ka Wing Ma wong Hoi She Wing Chiu Dai kenneth S.H.Chok Tan To Cheung Chung Mau Lo Department of Surgery The University of Hong KongHong KongChina

Background:We aimed to identify predictive factors for positron emission tomography(PET)-detected hepatocellular carcinoma(HCC)metastasis and a cost-effective approach to preoperative PET-computed tomography(CT)for detecting ***:Clinicopathological and survival data of HCC patients having PET-CT with 18F-fludeoxyglucose(FDG)and 11C-acetate(ACT)following contrast-enhanced CT/magnetic resonance imaging(MRI)for preoperative tumor staging were *** logistic regression was performed to identify predictive factors for PET-detected metastasis.A cost-benefit analysis model was built for the incurred costs and the impact of PET-CT findings on treatment strategy was ***:Totally 152 patients were ***-tracer PET-CT detected metastasis in 17 patients(11%).By multivariate analysis,alpha-fetoprotein(AFP)≥400 ng/mL[relative risk(RR):4.30,95%confidence interval(CI):1.41-13.15,P=0.011]and bilobar disease(RR:3.94,95%CI:1.24-12.52,P=0.014)were independent predictive factors for PET-detected ***-CT findings altered the treatment strategy for 12 patients(7.9%);three partial hepatectomies,eight episodes of transarterial chemoembolization(TACE)and one episode of ablation were avoided,with an estimated cost-saving of US$91,000,$150,000 and$10,600 *** the PET-CT been performed only for patients with AFP≥400 ng/mL or bilobar disease(n=74),metastasis would have been confirmed in 14 patients(18.9%),and the cost-saving per patient was estimated at US$1,***:Dual-tracer PET-CT is cost-effective and useful for preoperative HCC staging in patients with AFP≥400 ng/mL or bilobar *** routine use in preoperative workup for all HCC patients is not *** disease with AFPy procedures and is thus cost-effective for preoperative HCC workup.

关键词： Cost-effectiveness study dual-tracer positron emission tomography-computed tomography(dual-tracer PET-CT) hepatocellular carcinoma(HCC) metastatic screening preoperative investigation

Trap Behaviors of Constant Electric Field Stressing in Thin Oxynitride and Re-oxidized Oxynitride Films

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Chinese Physics Letters 1992年第9期9卷 479-482页

作者： yANG Bingliang LIU Baiyong H.wong y.C.Cheng Department of Applied Physics South China University of TechnologyGuangzhou 510641 Department of Electronic Engineering City Polytechnic of Hong kong Tat Chee Avenue KowloonHong Kong

The behaviors of constant electric field stressing of the thin(200Å)oxynitride and re-oxidized oxynitride films are *** flat-band shift is not a simple function of the stressing *** observed phenomena are attributed to the significance of trap filling,electronic tunneling and trap generation at different stressing field ***-oxidized sample is found to have high resistant to the electron tunneling and trap generation.

关键词： field oxidized tunneling

Pattern of disease recurrence and its implications for postoperative surveillance after curative hepatectomy for hepatocellular carcinoma: experience from a single center

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Hepatobiliary Surgery and Nutrition 2018年第5期7卷 320-330页

作者： kit-Fai Lee Charing C. N. Chong Anthony k. W. Fong Andrew k. y. Fung Hon-Ting Lok yue-Sun Cheung John wong Paul B. S. Lai Department of Surgery Division of Hepatobiliary and Pancreatic Surgery Prince of Wales Hospital the Chinese University of Hong Kong Hong Kong China

Background: Hepatectomy is a widely accepted curative treatment for hepatocellular carcinoma (HCC). However, the disease frequently recurs after a curative hepatectomy. The objective of this study is to provide a better understanding of the pattern of disease recurrence and the risk factors involved so as to improve the postoperative surveillance. Methods: A retrospective study for all patients receiving hepatectomy for HCC between 2003 and 2014 was performed. Emphasis was made on the timing and pattern of recurrent disease, and type of treatment given. Results: There were 506 patients in the study. Median follow-up was 43.7 months. The 1-, 3-, 5-, 10-year overall and disease free survival were 89.5%, 74.1%, 63.9%, 49.0% and 69.5%, 54.3%, 43.4%, 30.9%respectively. Recurrent disease occurred in 267 patients, 47.2% occurred within 9 months of hepatectomy and 80.1% recurred only in liver. Median survival was shorter for recurrence occurring within 9 months compared with those occurring between 10 months and 2 years postoperatively (36.2 vs. 65.7 months, Py (within 9 months) intrahepatic alone recurrence (22.2% vs. 51.7%, Pysis revealed tumor size >3.5 cm and history of rupture were risk factors for recurrence within 9 months. Conclusions: These findings suggest that recurrent diseases are common after curative hepatectomy for HCC and most recurrences occur in the remnant liver. Since almost half of recurrences occurred within first 9 months after hepatectomy, a more stringent postoperative surveillance with target imaging of liver in this period is needed. Early diagnosis of recurrent disease and curative retreatment hopefully can bring about a longer survival.

关键词： Hepatectomy hepatocellular carcinoma (HCC) recurrence

Fiber optical parametric oscillator based on highly nonlinear dispersion-shifted fiber

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Frontiers of Optoelectronics 2013年第1期6卷 25-29页

作者： Sigang yANG kenneth k. y. wong Minghua CHEN Shizhong XIE Tsinghua National Laboratory for Information Science and Technology (TNList) Department of Electrical Engineering Tsinghua University Beijing 100084 China The Photonic Systems Research Laboratory Department of Electrical and Electronic Engineering The University of Hong Kong Hong Kong China

The development of fiber optical parametric oscillators (FOPO) based on highly nonlinear dispersion-shifted fiber is reviewed in this paper. Firstly, the background and motivation are introduced, and it is pointed out that the FOPO is promising to act as optical source in non-conventional wavelength bands. Subsequently, the context focuses principally on the problem of inherent multiple-longitudinal-mode characteristic of FOPO and the corresponding solutions to it. The primary technique is by locking the phase of multiple longitudinal modes. The first reported actively mode locked FOPO is also presented in this article. However, it is not probable to realize passively mode locked FOPO because of the random phase dithering of the pump required for suppressing stimulated Brillouin scattering. Furthermore, a regeneratively mode locked FOPO is demonstrated, which can generate wide band tunable radiation in nonconventional wavelengths. Besides mode locked FOPO, the single-longitudinal-mode FOPO is also introduced. Finally, potential future directions are discussed.

关键词： fiber optical parametric amplifier (FOPA) fiber optical parametric oscillator (FOPO) mode locking single longitudinal mode

Noncontact photoacoustic lipid imaging by remote sensing on first overtone of the C-H bond

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Advanced Photonics Nexus 2023年第2期2卷 133-140页

作者： Guyue Hu Qiao Ran Beth Wing Lam So Mingsheng Li Jiawei Shi Xin Dong Jiqiang kang kenneth k.y.wong The University of Hong kong Faculty of EngineeringDepartment of Electrical and Electronic EngineeringHong KongChina The University of Hong kong School of Biological SciencesHong KongChina The University of Hong kong School of Biomedical SciencesLKS Faculty of MedicinePokfulamHong KongChina Hong kong Science Park Advanced Biomedical Instrumentation CentreHong KongChina

Lipid imaging by conventional photoacoustic microscopy subjects to direct contact sensing with relatively low detection bandwidth and sensitivity,which induces superficial imaging depth and low signalto-noise ratio(SNR)in practical imaging ***,we present a photoacoustic remote sensing microscopy for lipid distribution mapping in bio-tissue,featuring noncontact implementation,broad detection bandwidth,deep penetration depth,and high SNR.A tailored high-energy pulsed laser source with a spectrum centered at 1750 nm is used as the excitation beam,while a cofocused 1550 nm continuous-wave beam is used as the probe *** pump wavelength is selected to overlap the first overtone of the C-H bond in response to the intensive absorption of lipid molecules,which introduces a much-enhanced SNR(55 dB)onto photoacoustic remote sensing(PARS)***,the optical sensing scheme of the photoacoustic signals provides broadband detection compared to the acoustic transducer and refrains the bio-samples from direct contact operations by eliminating the ultrasonic coupling *** merits of the high detection sensitivity,deep penetration depth,broadband detection,and high resolution of the PARS system,high-quality tissue scale lipid imaging is demonstrated in a model organism and brain slice.

关键词： photoacoustic microscopy remote sensing lipid imaging near-infrared imaging label-free noncontact