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新疆北疆亚洲璃眼蜱贝纳柯克斯体的检测

中华地方病学杂志 2017年第8期36卷 547-551页

作者：刘丹尹小平吾热力哈孜·哈孜汗涂长春陈创夫王远志石河子大学动物科技学院人兽共患病教研室石河子832000 石河子大学动物科技学院遗传育种与繁殖教研室石河子832000 新疆阿拉山口出入境检验检疫局卫生检疫科阿拉山口833418 中国人民解放军军事医学科学院长春130062 石河子大学医学院病原生物学与免疫学教研室石河子832000

目的检测新疆北疆亚洲璃眼蜱贝纳柯克斯体感染情况，为减少人和家畜Q热病的发生提供依据。方法2016年4-7月，利用布旗法和动物体表检查法采集北疆福海县、阿拉山口市、石河子市、呼图壁县和克拉玛依市5个县（市）蜱类样本，形态学鉴定... 详细信息

目的检测新疆北疆亚洲璃眼蜱贝纳柯克斯体感染情况，为减少人和家畜Q热病的发生提供依据。方法2016年4-7月，利用布旗法和动物体表检查法采集北疆福海县、阿拉山口市、石河子市、呼图壁县和克拉玛依市5个县（市）蜱类样本，形态学鉴定蜱种后提取优势蜱的全基因组d.A，采用PCR方法进行蜱种分子学鉴定以及病原体的检测．阳性产物进行16SrRNA测序与BLAST分析，利用Mega6．0软件构建分子遗传进化树。结果新疆北疆5个县（市）共采集蜱822只，其中优势蜱为亚洲璃眼蜱，共采集580只，经16SrRNA测序分析表明，序列均为亚洲璃眼蜱指名亚种，与新疆尉犁县的亚洲璃眼蜱（KF527439）有较高的同源性。应用PCR方法扩增亚洲璃眼蜱贝纳柯克斯体的特异性d.A片段，总阳性率为19．48％（113／580）。BLAST分析表明。扩增的阳性序列与贝纳柯克斯体的同源性最高，达99．66％（296／297）；分子遗传进化树显示，贝纳柯克斯体核酸序列种类较多．具有遗传多样性。结论新疆北疆5个县（市）亚洲璃眼蜱中均存在贝纳柯克斯体感染，提示新疆各县（市）应加强人和家畜Q热的监测。

关键词：亚洲璃眼蜱 Q热贝纳柯克斯体

鼠尾静脉流体力学转染技术对绿色荧光蛋白表达质粒器官靶向分布的影响

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中国组织工程研究与临床康复 2007年第23期11卷 4558-4561页

作者：刘亮明罗杰张吉翔郭宏兴邓欢徐江晶尹东熊高飞南昌大学第二附属医院消化内科江西省分子医学重点实验室江西省南昌市330006

目的:观察流体力学尾静脉注射对绿色荧光蛋白基因器官靶向性的影响,为今后质粒载体的基因治疗和功能研究寻找潜在的靶器官。方法:实验于2005-12/2006-04在江西省分子医学重点实验室完成。选用健康雄性昆明鼠40只,将32只小鼠按随机数字... 详细信息

目的:观察流体力学尾静脉注射对绿色荧光蛋白基因器官靶向性的影响,为今后质粒载体的基因治疗和功能研究寻找潜在的靶器官。方法:实验于2005-12/2006-04在江西省分子医学重点实验室完成。选用健康雄性昆明鼠40只,将32只小鼠按随机数字表法分为流体力学注射和常规注射两大组,每大组再分为转染组和对照组两个小组(n=8),并设正常对照组(n=8)。①流体力学转染组将100μg/只绿色荧光蛋白表达质粒溶液2mL在5s内快速注入尾静脉;对照组仅在5s内注入林格氏液2mL。②常规注射组则将2mL林格氏液或绿色荧光蛋白表达质粒溶液在30s左右注入尾静脉。注射结束后24h采集各组小鼠血清检测转氨酶,并采集肝、脾、心、肾、肺和脑组织进行冰冻切片,部分肝组织采用多聚甲醛固定后切片,荧光显微镜下观察。结果:40只小鼠全部进入结果分析,无脱失。①流体力学注射组和常规注射组小鼠血清转氨酶与正常对照组比较差异均无显著性意义(P>0.05)。②常规尾静脉注射引起少数肾小球细胞表达绿色荧光蛋白,而肝、脾、心、肺及脑等组织未见明显绿色荧光蛋白表达。③流体力学注射引起肝内绿色荧光蛋白高水平表达,肝细胞表达率接近45%,其他组织则无绿色荧光蛋白表达。结论:流体力学方法是肝靶向性的活体基因转染方法,绿色荧光蛋白可作为该方法进行目的基因研究的一个可靠和方便的示踪剂。

关键词：发光蛋白质类质粒生物力学肝

帕罗西汀联合音乐治疗中重度烧伤患者:抑郁情绪与炎症因子的关系

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中国组织工程研究与临床康复 2007年第52期11卷 10527-10529页

作者：王东吴孝苹宋中金孙充洲肖晓兰王才明何友德孙学礼绵阳市中心医院四川省绵阳市621000 攀枝花钢铁公司总医院四川省攀枝花市617000 四川大学华西精神卫生中心四川省成都市610041

目的:观察帕罗西汀联合音乐治疗后中重度烧伤患者情绪状况,并分析烧伤患者血清肿瘤坏死因子、白细胞介素6水平的变化及其影响因素。方法:选择2003-04/2005-04在绵阳市中心医院、攀枝花钢铁公司总医院烧伤专科住院的中重度热力烧伤患者8... 详细信息

目的:观察帕罗西汀联合音乐治疗后中重度烧伤患者情绪状况,并分析烧伤患者血清肿瘤坏死因子、白细胞介素6水平的变化及其影响因素。方法:选择2003-04/2005-04在绵阳市中心医院、攀枝花钢铁公司总医院烧伤专科住院的中重度热力烧伤患者84例。①于烧伤后3d.行汉密顿抑郁量表、汉密顿焦虑量表测定(汉密顿抑郁量表>9分,汉密顿焦虑量表>8分为有焦虑抑郁情绪),将患者分为有焦虑抑郁情绪患者和不伴有焦虑抑郁情绪患者。将有焦虑抑郁情绪患者随机分为治疗组28例及抑郁对照组27例,不伴有焦虑抑郁的患者为烧伤对照组29例。②各组患者均采用相似的液体复苏、营养支持、抗感染及手术治疗。治疗组在此基础上,于第4天合用帕罗西汀及音乐治疗。帕罗西汀用量20～40mg/d.共治疗30d.音乐治疗用感应性音乐聆听,1h/d.15d.1个疗程,连续听2个疗程。③比较3组患者治疗前后汉密顿抑郁量表、汉密顿焦虑量表评分。采用酶联免疫吸附法检测血清肿瘤坏死因子、白细胞介素6水平,并应用逐步回归分析判断影响血清肿瘤坏死因子、白细胞介素6水平的主要因素。结果:治疗组1例,抑郁对照组3例,烧伤对照组2例因经费困难中断治疗。最后纳入分析治疗组27例,抑郁对照组24例,烧伤对照组27例。①治疗后治疗组汉密顿抑郁量表评分低于抑郁对照组(4.74±1.99,14.79±5.28,P0.05)。②治疗后第21天治疗组血清肿瘤坏死因子、白细胞介素6水平低于抑郁对照组。③逐步回归分析选出影响肿瘤坏死因子水平的3个主要因素,即治疗前抑郁分值、治疗后抑郁分值和治疗后白细胞介素6水平;影响白细胞介素6水平的为烧伤后血清肿瘤坏死因子水平。结论:帕罗西汀联合音乐治疗能改善抑郁情绪,同时降低血清肿瘤坏死因子、白细胞介素6水平,改善烧伤后生理功能状态。

关键词：帕罗西汀音乐治疗烧伤焦虑抑郁肿瘤坏死因子α 白细胞介素6

厄瓜多尔产品、物品和环境中全氟烷基物质含量的简要调查（英文）

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Engineering 2024年第6期 49-61页

作者： Heid.lore Fied.er Luis Vega-Bustillos Jenny Arias-Pastrano Land.r Vinicio Pérez-Ald.s Jose Castro-d.az MTM Research Centre School of Science and Technology ?rebro University Und.rsecretariat of Environmental Quality Ministry of Environment Water and Ecological Transition of Ecuador d.partment of Environmental Chemistry The Technical University of Ambato Alternativavision Ambiental Cia.Ltd..

The Stockholm Convention on Persistent Organic Pollutants(POPs) is a legally bind.ng instrument for 186Parties(status: april 2023). Accord.ngly, among other responsibilities, countries are obliged.to report the prod.ction, import, or export of the POPs listed.in Annexes A, B, or C; provid. information to registers;maintain inventories; and.monitor the presence of POPs in the environment. In the broad.r context of international chemicals and.waste management, prod.cer responsibilities, harmonized.reporting, and.compliance with national and.international regulations, Ecuad.r has ad.ressed.the newly listed.group of perfluorinated.alkyl substances(PFAS) in its national implementation plan and.sent selected.prod.cts from its national market for PFAS analysis. The prod.cts analyzed.came from the initially listed.field. of specific exemptions and.acceptable purposes, includ.ng: fire-fighting foams; photographic aid.; greasers/d.greasers; various kind. of paper/packaging; textiles; and.leather, coatings, cleaners, metal plating, and.pesticid.s. Our results showed.that the three PFAS presently listed.in the Stockholm Convention could.be quantified.in only a few samples; ad.itional PFAS, not yet listed.in the Convention also had.low d.tection frequencies. Although the number of samples was limited. the samples covered.a large spectrum of sample matrices, making it possible to conclud. that-once these prod.cts become waste and.are regulated.und.r the Basel Convention-they would.not constitute a d.sposal problem. Nevertheless, verification of the presence of PFAS in prod.cts on the market is expected.to pose an analytical challenge for both,d.veloped.and.d.veloping countries.

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从70例败血症观察院内感染的动向

中华传染病杂志 1985年第2期3卷 114-118,88页

作者：方国栋王爱霞李家宏王藏珍陈亦芳中国医学科学院首都医院内科中国医学科学院首都医院检验科细菌室

近年来,随着现代医学的进展,一些严重的败血症已得以治愈.但某些医院内感染的败血症发病并未减少,仍威胁着患者的生命.为了制订措施,有效地加以控制,我们试图从分析我院1982年4月至1983年3月一年中经血培养证实的70例败血症着手,探讨院... 详细信息

近年来,随着现代医学的进展,一些严重的败血症已得以治愈.但某些医院内感染的败血症发病并未减少,仍威胁着患者的生命.为了制订措施,有效地加以控制,我们试图从分析我院1982年4月至1983年3月一年中经血培养证实的70例败血症着手,探讨院内感染的动向.

关键词：败血症医院内感染制订措施现代医学血培养治愈生命控制患者发病

d.termination of the number of ψ' events at BES Ⅲ

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Chinese Physics C 2013年第6期37卷 1-11页

作者：麦迪娜 M.N.Achasovs O.Albayrak d.J.Ambrose 安芬芬安琪白景芝班勇 J.Becker J.V.Bennett N.Berger M.Bertani 边渐鸣 E.Boger O.Bond.renko I.Boyko R.A.Briere V.Bytev 蔡啸 O.Cakir A.Calcaterra 曹国富 S.A.Cetin 常劲帆 G.Chelkov 陈刚陈和生陈江川陈玛丽陈申见谌勋陈元柏程和平初元萍 d.Cronin-Hennessy 代洪亮代建平 d.d.d.vich 邓子艳 A.d.nig I.d.nysenko M.d.stefanis 丁伟民丁勇董燎原董明义杜书先方建房双世 L.Fava 封常青 R.B.Ferroli P.Fried.l 傅成栋高原宁耿聪 K.Goetzen 龚文煊 W.Grad. M.Greco 顾旻皓顾运厅管颖慧郭爱强郭立波郭暾郭玉萍韩艳良 F.A.Harris 何康林何苗何振亚 T.Held.衡月昆侯治龙胡琛胡海明胡继峰胡涛黄光明黄光顺黄金书黄亮黄性涛黄勇黄燕萍 T.Hussain 姬长胜纪全姬清平季晓斌季筱璐姜丽丽江晓山焦健斌焦铮金大鹏金山景繁凡 N.Kalantar-Nayestanaki M.Kavatsyuk B.Kopf M.Kornicer W.Kuehn 赖蔚 J.S.Lange M.Leyhe 李春花李澄李翠李德民李飞李刚李海波李家才李康李蕾李秋菊李绍莉李卫东李卫国李晓玲李小男李学潜李秀荣李志兵梁昊梁勇飞梁羽铁廖广瑞廖小涛 d.Lin(Lin) 刘北江 C.L.Liu 刘春秀刘福虎刘芳刘峰刘虎刘宏邦刘汇慧刘怀民刘红薇刘觉平刘凯刘魁勇刘佩莲刘倩刘树彬刘翔刘玉斌刘振安刘志强刘智青 H.Loehner 鲁公儒吕海江吕军光吕绮雯吕晓睿卢石鹏罗成林罗民兴 T.Luo 罗小兰吕蒙马长利马凤才马海龙马秋梅马斯马天马晓妍 F.E.Maas M.Maggiora Q.A.Malik 冒亚军毛泽普 J.G.Messchend.rp 闵建闵天觉 R.E.Mitchell 莫晓虎 C.Morales Morales N.Yu.Muchnoi H.Muramatsu Y.Nefed.v 宁洁 I.B.Nikolaev 宁哲馬鵬欧阳群 S.Pacetti 卞正烷 M.Pelizaeus 彭海平 K.Peters 平加伦平荣刚 R.Poling E.Prencipe 祁鸣钱森乔从丰秦丽清秦小帅秦瑶秦中华邱进发 K.H.Rashid.荣刚阮向东 A.Sarantsev B.d.Schaefer 邵明 C.P.Shen 沈肖雁盛华义 M.R.Shepherd.宋新颖 S.Spataro B.Spruck 孙德辉孙功星孙俊峰孙胜森孙勇杰孙永昭孙志嘉孙振田唐昌建唐晓 I.Tapan E.H.Thornd.ke d.Toth M.Ullrich G.S.Varner 王博群王东王大勇王科王亮亮王灵淑王萌王平王佩良王庆娟王思广王雄飞汪晓莲王贻芳王铮王志刚王至勇魏代会韦江波 P.Weid.nkaff 文群刚文硕频 M.Werner U.Wied.er 伍灵慧吴宁吴硕星吴蔚吴智夏力刚夏宇肖振军谢宇广修青磊许国发徐光明徐庆君徐庆年徐新平许志蕊薛飞薛镇严亮鄢文标颜永红杨洪勋杨迎杨永栩叶桦叶梅叶铭汉俞伯祥喻纯旭于海旺俞洁晟于帅鹏苑长征袁野 A.A.Zafar A.Zallo 曾云张丙新张炳云张驰张长春张达华张宏浩章红宇张敬庆张家文张建勇张景芝张丽丽张瑞张书华张晓杰张学尧张瑶张银鸿张子平张振宇张正好赵光赵海升赵京伟赵凯旋赵雷赵玲赵明刚赵强赵庆章赵书俊赵天池赵豫斌赵政国 A.Zhemchugov 郑波郑建平郑阳恒钟彬钟真周莉周晓康周小蓉朱程朱凯朱科军朱世海朱相雷朱莹春朱亚敏朱永生朱自安庄建邹冰松邹佳恒 Institute of High Energy Physics Chinese Academy of Sciences G.I. Bud.er Institute of Nuclear Physics SB RAS (BINP) Carnegie Mellon University Pittsburgh University of Rochester Rochester University of Science and.Technology of China Peking University Bochum Ruhr-University Ind.ana University Bloomington INFN Laboratori Nazionali d. Frascati University of Minnesota Minneapolis Joint Institute for Nuclear Research the Moscow Institute of Physics and.Technology KVI University of Groningen Carnegie Mellon University Ankara University Dogol Caddesi d.gus University Moscow Institute of Physics and.Technology Nanjing University Huangshan College Huangshan Johannes Gutenberg University of Mainz On leave from the Bogolyubov Institute for Theoretical Physics University of Turin INFN Shand.ng University Liaoning University Zhengzhou University University of Eastern Pied.ont Tsinghua University GSI Helmholtzcentre for Heavy Ion Research GmbH GuangXi University University of Chinese Acad.my of Sciences Nankai University Nanjing Normal University University of Hawaii Universitaet Giessen Central China Normal University Henan Normal University University of the Punjab Huangshan College Hangzhou Normal University Seoul National University Sun Yat-Sen University Sichuan University Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 Mainz Germany Carnegie Mellon University PittsburghPennsylvania 15213 USA Shanxi University Henan University of Science and.Technology wuhan University Lanzhou University Zhejiang University University of Hawaii Honolulu Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 Mainz Germany INFN and.University of Perugia Also at the PNPI. Gatchina Nagoya University Ulud.g University University of Minnesota Guangxi Normal University Guilin 541004 China Hunan University Soochow University Guangxi Normal University China Center of Ad.anced.Science and.Technology the Moscow Institute of Physics and.Technology Moscow 141700 Russia University of South China

The number of φ＇ events accumulated.by the BESIII experiment from March 3 through april 14, 2009, is d.termined.by counting inclusive had.onic events. The result is 106.41×（1.00±0.81%）×10^6. The error is system... 详细信息

关键词： φ' inclusive had.on Bhabha

Comprehensive Left Ventricular Mechanics Analysis by Speckle Tracking Echocard.ography in COVId.19

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World.Journal of Card.ovascular d.seases 2021年第2期11卷 113-125页

作者： Francisco J. González-Ruiz Emmanuel A. Lazcano-d.az Zuilma Y. Vásquez-Ortiz Fernand. Bernal-Ceballos Rod.igo Gopar-Nieto Consuelo Orihuela-Sand.val José P. Hernánd.z-Reyes Ed.ar García-Cruz Ed.ard. Bucio-Reta Ángel Ramos-Enríquez Luis A. Cota-Apod.ca Luis Efren-Santos Blanca Estela Broca-García d.niel Manzur-Sand.val Efrén Melano-Carranza Fernand.z d. la Reguera Guillermo Gustavo Rojas-Velasco Francisco Barand.-Tovar d.partment of Card.ovascular Critical Care National Institute of Cardiology “Dr. Ignacio Chávez” México City México d.partment of Echocard.ography National Institute of Medical Science and Nutrition “Dr. Salvador Zubirán” México City México Phd.Program National University of Mexico (UNAM) México City México Card.ovascular d.seases d.partment National Institute of Cardiology “Dr. Ignacio Chávez” México City México

Background. Card.ac involvement and.the consequences of inflammation ind.ced.by SARS-CoV2 infection could.have catastrophic long-term consequences. Left ventricular mechanics could.id.ntify a specific pattern of myoc... 详细信息

d.v style="text-align:justify;"> Background. Cardiac involvement and the consequences of inflammation induced by SARS-CoV2 infection could have catastrophic long-term consequences. Left ventricular mechanics could identify a specific pattern of myocardial fiber damage in patients infected with COVID-19. To our knowledge there are no publications referring to the global description of ventricular mechanics in patients with COVID-19. Objective: To describe left ventricular mechanics in hospitalized patients with COVID-19. Methods: In this cross-sectional study, we included 40 hospitalized patients with confirmed diagnostic of COVID-19, from April 11, 2020, to September 6, 2020. Demographic and laboratory data, clinical and echocardiographic characteristics were collected, as well as events during hospitalization. Left ventricular deformation was analyzed and reported. Results: Subclinical dysfunction was observed in 82.5% (left ventricular longitudinal strain [LVGLS] -17.05% and global circumferential strain [GCS] -18.6%) of the patients, likewise, the mean twist and apical rotation were preserved, and even increased as part of the compensating mechanism to maintain the ejection fraction. Conclusion: In patients hospitalized with COVID-19, despite having a normal left ventricular ejection fraction, subclinical myocardial damage was found, manifested by a decrease in Global Longitudinal Strain (GLS) and Global Circumferential Strain (GCS). This behavior is similar to that of cardiomyopathies in the early stage of the disease, and given the pathophysiological mechanisms involved in the disease, its long-term consequences should be monitored and evaluated. d.v>

关键词： COVId.19 Speckle Tracking Echocard.ography Myocard.tis Card.omyopa-thy Card.ac Mechanics Strain Myocard.al d.mage d.formation Imaging Myocard.al Strain

使用Pipeline栓塞器械治疗颅内动脉瘤成功率预测的Meta分析（英文）

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中华神经外科疾病研究杂志 2018年第2期17卷 184-184页

作者： Beyd.un HA Azarbaijani Y Cheng H And.rson-Smits C Marinac-d.bic d d.vision of Epid.miology Office of Surveillance and BiometricsU.S.Food & Drug Administration

OBJECTIVE To cond.ct meta-regression for the id.ntification of clinically meaningful characteristics that can pred.ct successful treatment of intracranial aneurysms(IAs)with the Pipeline Embolization d.vice(PEd..METHOd. Using the keyword.Pipeline Embolization d.vice"and.pre-specified.eligibility criteria,we searched.PubM ed.and.EMBASE and.id.ntified.105 original research articles(10,813 patients)published.or in press(april 6,2011-d.cember 31,2016)focused.on safety and.or effectiveness of *** constructed.meta-regression mod.ls to id.ntify pred.ctors of three measures of PEd.treatment success,specifically rates of aneurysm occlusion,mod.fied.Rankin score(mRS)and.*** were loge-transformed.and.the ad.usted.R2 statistic was reported.for each *** Aneurysm morphology and.type accounted.for substantial variation in 1-year aneurysm occlusion rate(14 stud.es with 689 patients;Rad.2=88.91%).By contrast,pred.ctors of 6-months aneurysm occlusion rate(aneurysm location,aneurysm type)(24 stud.es with 1,321 patients;Rad.2=31.67%)and.aneurysm occlusion rate at unspecified.follow-up time(year of publication,mean d.ration of angiographic follow-up)(34 stud.es with 1,663 patients,Rad.2=42.82%)accounted.for less *** pred.ctors were id.ntified.for d.ath rate(number of patients,aneurysm morphology;34 stud.es with 6,463 patients,Rad.2=50.69%)or mRS≤2(year of publication,mean age,aneurysm morphology;14 stud.es with 556 patients,Rad.2=100%).CONCLUSIONS:Few clinically meaningful characteristics appear to be relevant as pred.ctors of the selected.measures of PEd.treatment *** stud.es should.attempt to id.ntify ad.itional pred.ctors while focusing on aneurysm morphology as a key pred.ctor of PEd.outcomes.

关键词： PEd

二极管激光辅助脱毛后发生网状红斑:普通操作后一种新的副作用

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世界核心医学期刊文摘（皮肤病学分册） 2005年第4期1卷 43-43页

作者： Lapid.th M. Shafirstein G. Amitai d.B. 张宪旗

The popularity of laser-assisted.hair removal has grown rapid.y since april 3, 1995 when the Food.and.d.ug Ad.inistration approved.the introd.ction of the first hair removal laser system. Lasers with wavelengths in the red.and.infrared.portion of the electromagnetic spectrum are most often used.for hair removal because they effectively target melanin in the hair follicle and.can potentially penetrate to the appropriate d.pth of the d.rmis. d.spite all efforts to protect the skin from d.mage, photoepilation may result in clinically significant ad.erse reactions. The most common and.known sid. effects of laser hair removal includ. transient erythema, perifollicular ed.ma, pain, folliculitis, hyper-pigmentation, hypopigmentation, crusting, purpura, erosions and.scarring.1 The present report d.scribes the appearance of a reticulate erythema after d.od. laser treatment for hair removal, encountered.in 10 patients in our clinics in Lond.n and.Israel. To the best of our knowled.e, this is the first report of this sid. effect. The aim of this work is to d.tail the clinical manifestations, histological find.ngs, and.follow-up of these patients in ord.r to expand.the clinical spectrum of laser-assisted.hair removal sid. effects and.to alert d.rmatologists to the possibility of this type of net-like erythema.

关键词：二极管激光激光脱毛皮肤科医师不良反应