检索结果-南通市图书馆

Response of an old landslide to reservoir filling: A case history

在线全文

学校读者我要写书评

暂无评论

Science China(Technol.g.cal Sciences) 2005年第z1期48卷 27-32页

作者： l.g. Tham C.F. lee Department of Civil Engineering University of Hong Kong Hong Kong China

Unfavorable hydrodynamic evolution is considered as the major cause leading to reservoir slope instability and is often modeled by numerical method. However, this simulation is seldom checked by systematic field instrumentation. Taking the opportunity of filling the Three gorges Reservoir, a system was established in Xietan landslide to monitor reservoir water level, subground water level, seepage pressure, rainfall and deformation, etc. The monitored data during reservoir filling shows that: (1) The water level rise in the bank l.g. behind the reservoir filling and the l.g.time depends on the bank permeability; (2) rainfall-induced subground water rise and its l.g.time is closely correlated to hourly rainfall, indicating that it is not feasible or sufficient to use daily rainfall for analysis; (3) the effect of inverse seepage during reservoir filling on stability is ephemeral and reservoir filling is the major cause leading to bank instability.

关键词： reservoir filling, old landslide, monitoring system, water level, deformation.

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada Patrick Heimel Markus Kerbl lászl.g.l Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller David Hercher Department life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria ludwig Boltzmann Institute for Traumatol.g. The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autol.g.us nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNgCs). However, the use of tNgCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNgC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNgCs and compared the various features of these improved silk^(+) tNgCs with the tubes without holes(silk^(–) tNgCs) and autol.g.us nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histol.g.cal analyses, we were able to prove that the use of silk^(+) tNgCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autol.g.us nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNgCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNgCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNgCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

Microalgae Improve the Photosynthetic Performance of Rice Seedlings(Oryza sativa l.)under Physiol.g.cal Conditions and Cadmium Stress

在线全文

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2022年第7期91卷 1365-1380页

作者： Ekaterina Yotsova Martin Stefanov georgi Rashkov Margarita Kouzmanova Anelia Dobrikova Emilia apostolova Institute of Biophysics and Biomedical Engineering Bulgarian Academy of SciencesSofiaBulgaria Department of Biophysics and Radiobiol.g. Biological FacultySofia UniversitySofiaBulgaria

The aim of this study was to assess the impact of the microalgae Chlorella vulgaris on the rice seedlings at physiol.g.cal conditions and under cadmium(Cd)*** examined the effects of *** in the nutrient solution on rice seedlings grown hydroponically in the presence and the absence of 150μM CdCl2,using the low(77 K)temperature and pulse amplitude modulated(PAM)chlorophyll fluorescence,P700 photooxidation measurements,photochemical activities of both photosystems,kinetic parameters of oxygen evolution,oxidative stress markers(MDA,H_(2)O_(2) and proline),pigment content,growth parameters and Cd *** revealed that the application *** not only stimulates growth and improves the functions of photosynthetic apparatus under physiol.g.cal conditions,but also reduces the toxic effect of Cd on rice ***,the presence of the green microalgae in the nutrient solution of the rice seedlings during Cd exposure,signifi-cantly improved the growth,photochemical activities of both photosystems,the kinetic parameters of the oxygen-evolving reactions,pigment content and decreased lipid peroxidation,H_(2)O_(2) and proline *** showed that the alleviation of Cd-induced effects in rice seedlings is a result of the Cd sorption by microalgae,as well as the reduced Cd accumulation in the roots and its translocation from the roots to the shoots.

关键词： Chlorella vulgaris growth parameters low temperature chlorophyll fluorescence PAM chlorophyll fluorescence photosynthesis rice stress markers

Application and reliability analysis of DPM system in site investigation of HK weathered granite

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of University of Science and Technol.g. Beijing 2005年第6期12卷 481-488页

作者： Zhuoying Tan Meifeng Cai Zhongqi Yue l.g. Tham C.F. lee State Key laboratory of High-Efficient Mining and Safety of Metal Mines （University of Science and Technol.g. Beijing） Ministry of Education Beijing 100083 China Department of Civil Engineering University of Hong Kong Pokfulam Road Hong Kong China

A drilling process monitor （DPM） for ground characterization of weathered granite is presented. The monitor is portable and can be mounted on a hydraulic rotary drilling rig to record various drilling parameters in real time during normal subsurface investigation. The identification method for dominative and subsidiary interfaces has been established. The study reveals that the monitored drilling parameters are dependent on geotechnical materials and can be further applied to characterize ground interfaces. The t-test between manual l.g.ing and DPM l.g.ing has been carried out. The results show that the DPM has high accuracy in interfaces detection and well agreement with the manual l.g.ing. The findings show that the device and data analysis method are of potential application in subsurface drilling exploration in weathered granites. It also seems to have prospective uses in the determination of orebody boundary as well as in the detection of geohazards.

关键词： drilling process monitoring hydraulic rotary drill instrumented borehole drilling geotechnical engineering weathered granite

INVESTIgATION ON HOT DUCTIlITY AND STRENgTH OF CONTINUOUS CASTINg SlAB FOR AH32 STEEl

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English letters) 2006年第1期19卷 75-78页

作者： g. Y. li X.F. li l.g. Ao Technol.g. Center Anshan Iron and Steel Group CorporationAnshan 114009 China

By means of gleeble-1500 testing machine, the simulation of continuous casting process forAH32 steel was carried out and hot ductility and strength were determined. The cracking sensitivity was studied under the different temperatures and strain rates. The Precipitations of AIN at different temperatures and the fractures of high-temperature tensile samples were observed by using TEM （transmission electron microscope） and SEM （scanning electron microscope）. The factors affecting the brittle temperature zone were discussed.

关键词： continuous casting slab brittle temperature zone tensile strength,ductility simulation

Modelling Processes of Ink Transfer in Ink Units

在线全文

学校读者我要写书评

暂无评论

仪器仪表学报 2004年第S3期 93-94页

作者： E.A.Voronov ,l.g. Varepo Omsk Technical State University Omsk Russia 644010 Omsk Technical State University Omsk Russia 644010

Problems of modelling of the processes of ink distribution, inking and ink transfer are considered. An estimation of the ink layer non-uniformity on the printed impression and the instability of the ink feed within th... 详细信息

关键词： Modelling Ink distribution Ink tiansfer

Pro-resolving lipid mediator reduces amyloid-β42–induced gene expression in human monocyte–derived microglia

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 873-886页

作者： Ying Wang Xiang Zhang Henrik Biverstål Nicolas gBazan Shuai Tan Nailin li Makiko Ohshima Marianne Schultzberg Xiaofei li Department of Neurobiol.g. Care Sciences&SocietyDivision of NeurogeriatricsKarolinska InstitutetStockholmSweden Department of Neurol.g. Neuroscience CenterThe First Hospital of Jilin UniversityChangchunJilin ProvinceChina Department of Physiol.g. and Pharmacol.g. Karolinska InstitutetStockholmSweden Department of Biosciences and Nutrition Karolinska InstitutetHuddingeSweden Neuroscience Center of Excellence Louisiana State UniversityNew OrleansLAUSA Department of Medicine SolnaClinical Pharmacology GroupKarolinska University HospitalStockholmSweden

Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathol.g.. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte–derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42–induced Alzheimer's disease–like inflammation. Analysis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microglia showed that the monocyte-derived microglia resembled Alzheimer's disease–like neuroinflammation in human brain microglia after incubation with amyloid-β42. Maresin 1 restored homeostasis by down-regulating inflammatory pathway related gene expression induced by amyloid-β42 in monocyte-derived microglia, protection of maresin 1 against the effects of amyloid-β42 is mediated by a re-balancing of inflammatory transcriptional networks in which modulation of gene transcription in the nuclear factor-kappa B pathway plays a major part. We pinpointed molecular targets that are associated with both neuroinflammation in Alzheimer's disease and therapeutic targets by maresin 1. In conclusion, monocyte-derived microglia represent a relevant in vitro microglial model for studies on Alzheimer's disease-like inflammation and drug response for individual patients. Maresin 1 ameliorates amyloid-β42–induced changes in several.g.nes of importance in Alzheimer's disease, highl.g.ting its potential as a therapeutic target for Alzheimer's disease.

关键词： Alzheimer's disease amyloid-β maresin microglia monocyte neuroinflammation resolution RNA-sequencing specialized pro-resolving lipid mediator

在线全文

学校读者我要写书评

暂无评论

价值千金

价值千金

Multiple sclerosis is at a checkpoint: advancing the program

作者： .l.g.亚历山大(l.g. Alexander)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon C.Smith Jessica l.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biol.g.cal Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(CNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage