检索结果-南通市图书馆

耳蜗外淋巴液-脑脊液屏障的高效液相色谱研究

在线全文

学校读者我要写书评

暂无评论

第二军医大学学报 1999年第1期20卷 23-26页

作者：孙爱华 Parn.,ls 第二军医大学长征医院耳鼻咽喉科加拿大安大略西部大学耳鼻咽喉科

目的：探讨耳蜗外淋巴液（ＰＬ）－脑脊液（ＣＳＦ）屏障存在的直接证据。方法：以内源性激素氢化可的松（ＨＣ）和外源性激素甲泼尼龙（ＭＰ）为示踪剂，应用ＨＰＬＣ技术观察示踪剂在鼓阶外淋巴液（ＰＳＴ）、前庭阶外淋巴液（ＰＳＶ... 详细信息

目的：探讨耳蜗外淋巴液（ＰＬ）－脑脊液（ＣＳＦ）屏障存在的直接证据。方法：以内源性激素氢化可的松（ＨＣ）和外源性激素甲泼尼龙（ＭＰ）为示踪剂，应用ＨＰＬＣ技术观察示踪剂在鼓阶外淋巴液（ＰＳＴ）、前庭阶外淋巴液（ＰＳＶ）、中阶内淋巴液（ＳＭＥ）、ＣＳＦ以及血液中的动力学变化特征。结果：鼓室内注射ＨＣ１ｈ后，ＰＳＴ和ＰＳＶ中ＨＣ浓度几乎完全相同；注射后１～２ｈ，ＰＳＴ，ＰＳＶ中ＨＣ浓度同步快速降低；２～６ｈ期间，ＨＣ浓度降幅趋缓；而ＣＳＦ中ＨＣ浓度为０。鼓室内注射ＭＰ后，很快同时出现在ＰＳＴ和ＰＳＶ中，两阶ＰＬ各时间测值差异不显著；ＣＳＦ中ＭＰ为０。ＳＭＥ中ＨＣ和ＭＰ的各时间测值均显著高于ＰＳＶ，ＰＳＴ。结论：耳蜗小管不存在开放性自由通道使ＰＳＴ与ＣＳＦ直接沟通，ＣＳＦ亦不能经耳蜗小管直接进入鼓阶替换或取代ＰＬ。

关键词：耳蜗小管外淋巴液脑脊液屏障示踪剂

Relationship between Obsessive-Compulsive Symptoms and Anxiety Levels during the COVID-19 Pandemic in Healthcare Professionals ***-Healthcare Professionals

在线全文

学校读者我要写书评

暂无评论

International Journal of Mental Health Promotion 2022年第3期24卷 399-413页

作者： Faruk Kurhan Gülsüm Zuhal Kamış Emine Füsun AkyüzÇim Abdullah Atli Dilem Dinc Department of Psychiatry Faculty of Medicine Yuzuncu Yil UniversityVanTurkey Department of Psychiatry Bilkent City HospitalAnkaraTurkey Department of Psychiatry Florence Nightingale HospitalİstanbulTurkey Department of Psychiatry Medical School of Dicle UniversityDiyarbakirTurkey Department of Psychology Kahramanmaras Istiklal UniversityKahramanmarasTurkey

The present study investigated the effect of the COVID-19 pandemic on anxiety levels,contamination and responsibility/control obsessions and associated OC behaviors in healthcare versus non-healthcare *** study also aimed to examine the relationship between anxiety levels and obsessive-compulsive(OC)symptom levels,gender,age,educational level,and personal and family history of chronic *** 664 participants included 395(59.5%)men and 269(40.5%)women and comprised 180(27.1%)healthcare professionals and 484(72.9%)non-healthcare *** survey included three data collection tools:(i)Sociodemographic data form,(ii)Beck Anxiety Inventory(BAI),and(iii)the Dimensional Obsessive-Compulsive Scale Abriged(DOCS-A)pre-and post-pandemic *** BAI scores established a moderate positive correlation with post-pandemic DOCS-A total scores and a weak positive correlation with pre-pandemic DOCS-A total scores(pls and OC symptom *** was also revealed that female gender and personal or family history of chronic diseases posed a higher risk for the increase in anxiety and OC symptoms and healthcare professionals had a higher risk of developing anxiety symptoms compared to non-healthcare professionals.

关键词： Pandemic healthcare professionals non-healthcare professionals obsessive behavior

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

对环境污染、农药与癌症预防的误解

国外医学（卫生学分册） 1997年第6期24卷 356-359页

作者： Ames BN Gold ls 美国环境卫生科学研究所

引起癌症的主要原因有：吸烟、不平衡膳食、慢性传染病和激素因素。最近的研究表明：（１）啮齿类动物的致癌剂并不罕见。在标准的大剂量动物致癌试验中测试的化学物质，不论是天然的还是人工合成的，半数都是“致癌剂”；（２）啮齿类... 详细信息

引起癌症的主要原因有：吸烟、不平衡膳食、慢性传染病和激素因素。最近的研究表明：（１）啮齿类动物的致癌剂并不罕见。在标准的大剂量动物致癌试验中测试的化学物质，不论是天然的还是人工合成的，半数都是“致癌剂”；（２）啮齿类动物致癌试验中的致癌剂量很高，与低剂量的人类接触无关。动物试验所用剂量很高，正是使许多所试化学物质得出阳性结果的原因所在；（３）尽管在人类摄入的化学物质中有９９．９％都是天然的，但是管理政策依然瞄准人工合成的化学物质。人类食用的植物中有数千种天然杀虫剂：在已测试的６３种中有３５种是啮齿类动物的致癌剂。还没有令人信服的证据证明合成的化学污染物在人类癌症形成中发挥了重要作用。要消除极低水平的合成化学物质需要投入巨额资金，据美国环保局估计进行这样的环境治理每年需耗资１４００亿美元。癌症的预防要靠生物医学研究所获得的知识、公众的宣传教育和改变不良的生活方式。似乎有必要对目前的（包括公众和个人的）癌症预防重点进行重新审查。

关键词：环境污染农药肿瘤预防

EXAFS study of cation reordering in NaYF_4:Yb^(3+),Tb^(3+) up-conversion luminescence materials

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2014年第3期32卷 226-229页

作者： H.F.Brito J.Hls T.Laamanen T.Laihinen M.Lastusaari L.Pihlgren L.C.V.Rodrigues T.Soukka Instituto de Química Universidade de S?o Paulo Department of Chemistry University of Turku Turku University Centre for Materials and Surfaces (MatSurf) Department of Chemistry University of Turku FI-20014 Turku Finland Turku University Centre for Materials and Surfaces (MatSurf) Turku Finland University of Turku Graduate School (UTUGS) Doctoral Programme in Physical and Chemical Sciences Graduate School of Materials Research (GSMR) Department of Biochemistry University of Turku

The NaYF4：yb3＋,Tb3＋（Xyb： 0.20, XTb： 0.04） materials were prepared using the co-precipitation method, lne as-preparea material was washed either with or without water in addition to ethanol and thereafter annealed for 5 h at 500℃. This resulted in materials with moderate or very high up-conversion luminescence intensity, respectively. The structural study carried out with X-ray powder diffraction revealed microstrains in the rare earth （R） sublattice that were relaxed for the material with very high up-conversion intensity thus decreasing energy losses. The local structural details were investigated with R LⅢ and Y K edge ex- tended X-ray absorption fine structure （EXAFS） using synchrotron radiation. Around 10 tool.% of the Yb3＋ ions were found to occupy the Na site in the material with very high up-conversion intensity. These Yb species formed clusters with the Tb3＋ ions occupying the regular Na/R sites. Such clustering enhanced the energy transfer between Yb3＋ and Tb3＋ thus intensifying the up-conversion emission.

关键词： EXAFS up-conversion ytterbium terbium cation reordering

连续油管快速柱创造下井20500ft的新记录

在线全文

学校读者我要写书评

暂无评论

油气田开发工程译丛 1993年第3期 30-32页

作者： Adam.,ls 杜志彬

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

单克隆抗体的免疫学和药理学概念(续)

国外医学（放射医学核医学分册） 1990年第2期14卷 85-93页

作者： Zuckier ls 李怀芬牛惠生

人Ig中,IgG的T_(1/2)最长(T_(1/2)平均值为21天),其余依次为IgA(6天),IgM(5天),IgD(2.8天)和IgE(2.7天),如表1所示.IgG_3的T_(1/2)比IgG的其他亚型短(7.1天),而两个IgA亚型有相似的T_(1/2),血管内IgG存活用^(35)S生物合成制备标记的Ig证... 详细信息

关键词：单克隆抗体碘免疫放射性标记

Particle Size Distribution,Powder Agglomerates and Their Effects on Sinterability of Ultrafine Alumina Powders

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2000年第4期16卷 393-396页

作者： Renjie ZENG (Dept. of Materials Science, University of Xiamen, Xiamen 361005, China) B.Rand (Dept.of Materials, University of Leeds, Leeds ls2 9JT, England) Dept. of Materials Science University of Xiamen Xiamen 361005 China Dept. of Materials University of Leeds Leeds LS2 9JT United Kingdom

An intensive study of the particle size distribution of four commercial ultrafine alumina powders to obtain information about the powder agglomeration and relate them to the compactibility and the sinterability has be... 详细信息

关键词： rate Particle Size Distribution,Powder Agglomerates and Their Effects on Sinterability of Ultrafine Alumina Powders AKP than