检索结果-南通市图书馆

QoS Routing Optimization Based on Deep Reinforcement Learning in SDN

Computers, Materials & Continua 2024年第5期79卷 3007-3021页

作者： Yu song Xusheng Qian Nan Zhang Wei Wang ao Xiong State Key Laboratory of Networking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing100876China Marketing Service Center State Grid Jiangsu Electric Power Co.Ltd.Nanjing220000China Customer Service Center State Grid Co.Ltd.Nanjing211161China

To enhance the efficiency and expediency of issuing e-licenses within the power sector, we must confront thechallenge of managing the surging demand for data traffic. Within this realm, the network imposes stringentQuality of Service (QoS) requirements, revealing the inadequacies of traditional routing allocation mechanismsin accommodating such extensive data flows. In response to the imperative of handling a substantial influx of datarequests promptly and alleviating the constraints of existing technologies and network congestion, we present anarchitecture forQoS routing optimizationwith in SoftwareDefinedNetwork (SDN), leveraging deep reinforcementlearning. This innovative approach entails the separation of SDN control and transmission functionalities, centralizingcontrol over data forwardingwhile integrating deep reinforcement learning for informed routing decisions. Byfactoring in considerations such as delay, bandwidth, jitter rate, and packet loss rate, we design a reward function toguide theDeepDeterministic PolicyGradient (DDPG) algorithmin learning the optimal routing strategy to furnishsuperior QoS provision. In our empirical investigations, we juxtapose the performance of Deep ReinforcementLearning (DRL) against that of Shortest Path (SP) algorithms in terms of data packet transmission delay. Theexperimental simulation results show that our proposed algorithm has significant efficacy in reducing networkdelay and improving the overall transmission efficiency, which is superior to the traditional methods.

关键词： Deep reinforcement learning SDN route optimization QoS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Discovery of proqodine A derivatives with antitumor activity targeting NAD(P)H:quinone oxidoreductase 1 and nicotinamide phosphoribosyltransferase

引用

Chinese Journal of Natural Medicines 2024年第1期22卷 75-88页

作者： song Jiangzhou ZOU Guiqing ZHao Zhou ZHU Ya XUE Jiayu ao Lanjia SUN Huiyong Hao Haiping ZHANG Bo XU Xiaowei State Key Laboratory of Natural Medicines Key Lab of Drug Metabolism and PharmacokineticsChina Pharmaceutical UniversityNanjing 210009China State Key Laboratory of Natural Medicines China Pharmaceutical UniversityNanjing 210009China

NAD(P)H:quinone oxidoreductase 1(NQO1)is a flavin protease highly expressed in various cancer cells.NQO1 catalyzes a futile redox cycle in substrates,leading to substantial reactive oxygen species(ROS)production.This ROS generation results in extensive DNA damage and elevated poly(ADP-ribose)polymerase 1(PARP1)-mediated consumption of nicotinamide adenine dinucleotide(NAD^(+)),ultimately causing cell death.Nicotinamide phosphoribosyltransferase(NAMPT),the rate-limiting enzyme in the NAD^(+)salvage synthesis pathway,emerges as a critical target in cancer therapy.The concurrent inhibition of NQO1 and NAMPT triggers hyperactivation of PARP1 and intensive NAD+depletion.In this study,we designed,synthesized,and assessed a novel series of proqodine A derivatives targeting both NQO1 and NAMPT.Among these,compound T8 demonstrated potent antitumor properties.Specifically,T8 selectively inhibited the proliferation of MCF-7 cells and induced apoptosis through mechanisms dependent on both NQO1 and NAMPT.This discovery offers a promising new molecular entity for advancing anticancer research.

关键词： NQO1 ROS NAMPT NAD^(+) T8

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

All-Polymer Solar Cells and Photodetectors with Improved Stability Enabled by Terpolymers Containing Antioxidant Side Chains

引用

Nano-Micro Letters 2023年第9期15卷 190-204页

作者： Chunyang Zhang Ao Song Qiri Huang Yunhao Cao Zuiyi Zhong Youcai Liang Kai Zhang Chunchen Liu Fei Huang Yong Cao Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and DevicesSouth China University of TechnologyGuangzhou 510640People’s Republic of China

It is of vital importance to improve the long-term and photostability of organic photovoltaics,including organic solar cells(OSCs)and organic photodetectors(OPDs),for their ultimate industrialization.Herein,two series of terpolymers featuring with an antioxidant butylated hydroxytoluene(BHT)-terminated side chain,PTzBI-EHp-BTBHTx and N2200-BTBHTx(x=0.05,0.1,0.2),are designed and synthesized.It was found that incorporating appropriate ratio of benzothiadiazole(BT)with BHT side chains on the conjugated backbone would induce negligible effect on the molecular weight,absorption spectra and energy levels of polymers,however,which would obviously enhance the photostability of these polymers.Consequently,all-polymer solar cells(all-PSCs)and photodetectors were fabricated,and the all-PSC based on PTzBI-EHp-BTBHT0.05:N2200 realized an optimal power conversion efficiency(PCE)approaching~10%,outperforming the device based on pristine PTzBI-EHp:N2200.Impressively,the all-PSCs based on BHT-featuring terpolymers displayed alleviated PCEs degradation under continuous irradiation for 300 h due to the improved morphological and photostability of active layers.The OPDs based on BHT-featuring terpolymers achieved a lower dark current at−0.1 bias,which could be stabilized even after irradiation over 400 h.This study provides a feasible approach to develop terpolymers with antioxidant efficacy for improving the lifetime of OSCs and OPDs.

关键词： Organic photovoltaics Device operational stability All-polymer solar cell Organic photodetector Antioxidant

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Global multifaceted biodiversity patterns,centers,and conservation needs in angiosperms

引用

Science China(Life Sciences) 2024年第4期67卷 817-828页

作者： ao Luo Yaoqi Li Nawal Shrestha Xiaoting Xu Xiangyan Su Yichao Li Tong Lyu Kilara Waris Zhiyao Tang Xiaojuan Liu Luxiang Lin Yongsheng Chen Kuiling Zu Wenqi song Shijia Peng Niklaus E.Zimmermann Loïc Pellissier Zhiheng Wang Institute of Ecology and Key Laboratory for Earth Surface Processes of the Ministry of Education College of Urban and Environmental SciencesPeking UniversityBeijing 100871China Department of Health and Environmental Sciences Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China State Key Laboratory of Grassland Agro-Ecosystems College of EcologyLanzhou UniversityLanzhou 730000China Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education College of Life SciencesSichuan UniversityChengdu 610065China Land Consolidation and Rehabilitation Center Ministry of Natural ResourcesBeijing 100035China State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China CAS Key Laboratory of Tropical Forest Ecology Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesKunming 650201China Swiss Federal Research Institute WSL Birmensdorf 8903Switzerland Department of Environmental Systems Science ETH ZürichZürich 8092Switzerland

The Convention on Biological Diversity seeks to conserve at least 30%of global land and water areas by 2030,which is a challenge but also an opportunity to better preserve biodiversity,including flowering plants(angiosperms).Herein,we compiled a large database on distributions of over 300,000 angiosperm species and the key functional traits of 67,024 species.Using this database,we constructed biodiversity-environment models to predict global patterns of taxonomic,phylogenetic,and functional diversity in terrestrial angiosperms and provide a comprehensive mapping of the three diversity facets.We further evaluated the current protection status of the biodiversity centers of these diversity facets.Our results showed that geographical patterns of the three facets of plant diversity exhibited substantial spatial mismatches and nonoverlapping conservation priorities.Idiosyncratic centers of functional diversity,particularly of herbaceous species,were primarily distributed in temperate regions and under weaker protection compared with other biodiversity centers of taxonomic and phylogenetic facets.Our global assessment of multifaceted biodiversity patterns and centers highlights the insufficiency and unbalanced conservation among the three diversity facets and the two growth forms(woody vs.herbaceous),thus providing directions for guiding the future conservation of global plant diversity.

关键词： angiosperms species richness phylogenetic diversity functional diversity plant traits woody species herbaceous species

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Metal-ligand cooperative iridium complex catalyzed C-alkylation of oxindole and 1,3-dimethylbarbituric acid using alcohols

绿色合成与催化(英文)

引用

绿色合成与催化(英文) 2023年第3期4卷 246-252页

作者： Ao Song Yunbo Liu Xuan Jin Dianrun Su Zhaopeng Li Shengsheng Yu Lingbao Xing Xiangchao Xu Rongzhou Wang Feng Li School of Chemistry and Chemical Engineering Shandong University of TechnologyZibo255000China School of Chemistry and Chemical Engineering Nanjing University of Science&TechnologyNanjing210094China

A general and high-efficiency C-alkylation of oxindoles and barbituric acids has been developed by a Cp*Ir complex[Cp*Ir(2,20-bpyO)(OH)]Na with a bipyridine-based functional ligand.In particular,H_(2)O was selected as the solvent instead of the organic solvent in this catalytic system.Through mild reaction conditions gave a variety of corresponding alkylated heterocyclic compounds with good to excellent yields.More importantly,the gramscale C-alkylation reaction was successfully carried out with good yield using a common route with only a single purification by column chromatography.

关键词： C-Alkylation Borrowing hydrogen Iridium complex Oxindole 1,3-Dimethylbarbituric acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

不同播期对薏苡籽粒中淀粉积累规律、产量及药用品质的影响

引用

分子植物育种 2024年第10期22卷 3306-3311页

作者：宋智琴敖茂宏杨小雨贵州省农业科学院农作物品种资源研究所贵阳550006 贵州省农业科学院亚热带作物研究所兴义562400

为了研究不同播期对薏苡籽粒中淀粉积累规律、产量及药用品质的影响,以确定合理的最佳播种时间。本研究选取‘仁薏1号’为试验材料,设置8个播期,在开花后不同时间段测试总淀粉、支链淀粉含量、直链淀粉含量、收获期测定产量、检测成熟... 详细信息

为了研究不同播期对薏苡籽粒中淀粉积累规律、产量及药用品质的影响,以确定合理的最佳播种时间。本研究选取‘仁薏1号’为试验材料,设置8个播期,在开花后不同时间段测试总淀粉、支链淀粉含量、直链淀粉含量、收获期测定产量、检测成熟籽粒中药用指标成分。结果表明,薏苡籽粒中总淀粉含量随着灌浆时间的延长而增加,成熟期总淀粉含量达到最大值。过早播种会影响籽粒中总淀粉、支链淀粉的积累,过早或过晚播种都会影响籽粒直链淀粉积累。不同播期处理对薏苡药用指标成分和产量产生影响。适时播种,籽粒中的药用品质成分(浸出物,三油酸甘油酯)含量和亩产量都较高,过早或过晚播种都会使药用成分和产量降低。因此,根据贵州气候特点和春耕时间,结合籽粒中的营养品质、药用品质和产量综合分析,贵州薏苡最佳播种时间应为3月下旬至4月上旬。

关键词：播期薏苡淀粉含量药用品质产量

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Highly efficient organic solar cells with improved stability enabled by ternary copolymers with antioxidant side chains

引用

Journal of Semiconductors 2023年第8期44卷 48-56页

作者： Ao Song Qiri Huang Chunyang Zhang Haoran Tang Kai Zhang Chunchen Liu Fei Huang Yong Cao Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and DevicesSouth China University of Technology(SCUT)Guangzhou 510640China

The stability of organic solar cells(OSCs)remains a major concern for their ultimate industrialization due to the photo,oxygen,and water susceptibility of organic photoactive materials.Usually,antioxidant additives are blended as radical scavengers into the active layer.However,it will induce the intrinsic morphology instability and adversely affect the efficiency and long-term stability.Herein,the antioxidant dibutylhydroxytoluene(BHT)group has been covalently linked onto the side chain of benzothiadiazole(BT)unit,and a series of ternary copolymers D18-Cl-BTBHTx(x=0,0.05,0.1,0.2)with varied ratio of BHT-containing side chains have been synthesized.It was found that the introduction of BHT side chains would have a negligible effect on the photophysical properties and electronic levels,and the D18-Cl-BTBHT0.05:Y6-based OSC achieved the highest power conversion efficiency(PCE)of 17.6%,which is higher than those based active layer blended with BHT additives.More importantly,the unencapsulated device based on D18-Cl-BTBHTx(x=0.05,0.1,0.2)retained approximately 50%of the initial PCE over 30 hours operation under ambient conditions,significantly outperforming the control device based on D18-Cl(90%degradation in PCE after 30 h).This work provides a new structural design strategy of copolymers for OSCs with simultaneously improved efficiency and stability.

关键词： organic solar cells ternary copolymers antioxidant side chain photostability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

飞龙掌血蜂蜜挥发性物质组成及关键香气物质分析

引用

食品科学 2024年第11期45卷 175-185页

作者：姜澳黎洪霞刘肇龙宋梅李娜陈兰珍资源昆虫高效养殖与利用全国重点实验室中国农业科学院蜜蜂研究所北京100093 农业农村部蜂产品质量安全风险评估实验室(北京) 北京100093

为明确中国特色中药材蜂蜜——飞龙掌血蜂蜜的挥发性物质组成及香气特征,利用阿贝折光仪、高效液相色谱仪、紫外分光光度计等分别对其水分含量、糖类含量、淀粉酶活性、抗氧化能力等指标进行测定。同时,利用顶空-固相微萃取结合气相色谱... 详细信息

为明确中国特色中药材蜂蜜——飞龙掌血蜂蜜的挥发性物质组成及香气特征,利用阿贝折光仪、高效液相色谱仪、紫外分光光度计等分别对其水分含量、糖类含量、淀粉酶活性、抗氧化能力等指标进行测定。同时,利用顶空-固相微萃取结合气相色谱-四极杆飞行时间质谱仪对其挥发性成分进行定性定量分析。结果表明:飞龙掌血蜂蜜样品的水分质量分数为(18.71±1.49)%,果糖和葡萄糖质量分数分别为(35.92±2.70)%和(35.85±2.51)%,1,1-二苯基-2-三硝基苯肼自由基和2,2’-联氮双(3-乙基苯并噻唑啉-6-磺酸)阳离子自由基的半清除浓度分别为(57.18±7.62)mg/mL和(247.68±40.50)mg/mL,淀粉酶活力为(11.84±3.38)mL/(g·h)。从飞龙掌血蜂蜜中共鉴定出176种挥发性物质,主要包括烃类52种、酯类29种、醇类21种、萜烯类21种、醛类17种和芳香族类12种等。其中苯甲醛、苯乙醇、1-辛烯-3-醇的含量较高,分别为8 181.9、4 483.1μg/kg和4 239.5μg/kg。经香气活度值分析鉴定出42种关键香气化合物(OAV>1),包括大马士酮、苯乙酸甲酯、α-水芹烯等,这些物质对飞龙掌血蜂蜜香气组成具有重要贡献。其中紫罗酮具有紫罗兰花香气,赋予了飞龙掌血蜂蜜独特的紫罗兰、覆盆子芳香味。飞龙掌血蜂蜜主要以花香味为主,辅以果香味、化学味和青香味的香气。综上,飞龙掌血蜂蜜的理化指标均满足相关标准,且挥发性成分种类丰富。本研究可为飞龙掌血蜂蜜品质评价提供数据支持,并为其他特色中药材蜂蜜的挖掘提供研究思路。

关键词：飞龙掌血蜂蜜顶空-固相微萃取-气相色谱-四极杆飞行时间质谱挥发性成分关键香气化合物

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

中国濒危药用植物出口贸易时空格局分析

引用

植物科学学报 2024年第2期42卷 211-220页

作者：金敖宋诗雯何拓袁良琛曾会明北京林业大学草业与草原学院北京100083 国家林业和草原局野生动物保护监测中心北京100714 国家林业和草原局野生动植物保护司北京100714

药用植物是《濒危野生动植物种国际贸易公约》(Convention on International Trade in Endangered Species of Wild Fauna and Flora,简称CITES)国际贸易中的重要类群。本文基于CITES贸易数据库,通过描述统计法和Pearson相关系数法探究C... 详细信息

药用植物是《濒危野生动植物种国际贸易公约》(Convention on International Trade in Endangered Species of Wild Fauna and Flora,简称CITES)国际贸易中的重要类群。本文基于CITES贸易数据库,通过描述统计法和Pearson相关系数法探究CITES附录药用植物在中国的出口贸易时空格局。结果显示,中国在1981-2021年,有257种药用植物用于贸易,其中活体植物总贸易量达1.7亿株,植物衍生物总贸易量达10万吨。中国药用植物的出口贸易记录主要集中在日本(32%)、韩国(10%)和美国(9%),并逐渐向更多的国家或地区发展。Pearson相关系数分析表明,随着CITES贸易管制措施在中国的实施,药用植物的贸易来源逐渐由野生转变为人工培植。植物衍生物这一标本类型的药用植物需要更加关注,天麻(Gastrodia elata Blume)、西洋参(Panax quinquefolius L.)、建兰(Cymbidium ensifolium(L.)Sw.)、纹瓣兰(Cymbidium aloifolium(L.)Sw.)则是需要在贸易中重点监督的物种。

关键词：濒危药用植物 CITES 贸易时空格局

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

利多卡因联用硫化氢供体分子的镇痛作用研究

引用

华西药学杂志 2024年第3期39卷 243-246页

作者：陈春霞康婷海澳柯博文宋颢四川大学华西药学院四川成都610041 四川大学华西临床医学院华西医院四川成都610041

目的研究气体信号分子硫化氢对利多卡因镇痛作用的影响。方法以硫氢化钠作为硫化氢供体分子,与利多卡因联用,通过对小鼠的多类型疼痛行为学、足肿胀度、HE染色等进行系统评估,探究硫化氢对利多卡因镇痛作用的影响。结果与利多卡因组比较... 详细信息

目的研究气体信号分子硫化氢对利多卡因镇痛作用的影响。方法以硫氢化钠作为硫化氢供体分子,与利多卡因联用,通过对小鼠的多类型疼痛行为学、足肿胀度、HE染色等进行系统评估,探究硫化氢对利多卡因镇痛作用的影响。结果与利多卡因组比较,利多卡因联用高、中剂量的硫氢化钠(30、15μmol·kg^(-1))对各小鼠疼痛模型均有显著镇痛作用,同时,能显著减轻炎症小鼠后爪的肿胀度和炎症细胞浸润。结论联用硫化氢有助于增强利多卡因的镇痛和抗炎作用。

关键词：气体信号分子硫化氢供体利多卡因镇痛抗炎联合用药

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：