检索结果-南通市图书馆

Pregnancy outcome of day 3versus day 5 embryo transfer: A retrospective analysis

在线全文

学校读者我要写书评

暂无评论

Asian pacific Journal of Reproduction 2017年第2期6卷 89-92页

作者： Samaher Alfaraj Fatima Alzaher Sahar Alshwaiaer anwar ahmed Department of Obstetrics and Gynecology Reproductive Endocrinology and Infertility UnitKing Abdul-Aziz Medical CityRiyadhSaudi Arabia Department of Obstetrics and Gynecology Ministry of HealthDammamSaudi Arabia Assistant Professor of Biostatistics Department of Epidemiology and Biostatistics College of Public Health and Health Informatics King Saud Bin Abdulaziz University for Health Sciences National Guard Health Affairs RiyadhKSA

Objective:To compare the pregnancy rate between day 3 and day 5 transfer regardless grades of embryos and number of transferred ***: Retrospective cohort, a total of seven hundred and four patients met our inclusion criteria, with 411 had day 3 embryo transfer and 293 had day 5 embryo transfer. The patients who were older than 40 years old were excluded. Embryo transfer was carried out in all patients in both transfer ***:Both clinical pregnancy rate and implantation rate did not show any statistically significant difference between the day 3 and day five transfer groups. These were 44%vs. 45% withP=0.82 and 19%vs. 19% withP=0.99 respectively. An increase of miscarriage rate with day 5 embryo transferred compare with day 3 (12.0%vs. 4.4%,P=0.01), but no significant difference was found about biochemical pregnancy rate (P=0.52).Conclusions:Transferring embryo at day 5 may not provide any additional benefit over day 3 transfers to patients. In addition, it increases the risk of miscarriage. Further studies of this issue needed for confirming our findings.

关键词： Embryo transfer Blastocyst Early cleavage stage Pregnancy outcomes Sequential culture media

Inhibition of HeLa cell growth by doxorubicin-loaded and tuftsinconjugated arginate-PEG microparticles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2018年第1期3卷 48-54页

作者： Tianmu Hu anwar Saeed ahmed Qahtan Lei Lei Zhixin Lei Dapeng Zhao Hemin Nie Institute of Bionanotechnology and Tissue Engineering College of Life SciencesHunan UniversityChangsha410082China Department of Orthodontics Xiangya Stomatological HospitalCentral South UniversityChangsha410008China Changsha DMY Medical Technology Co. LtdChangsha410005China Shenzhen Research Institute of Hunan University Nanshan Hi-new Technology and Industry ParkShenzhen518057China

In order to improve the release pattern of chemotherapy drug and reduce the possibility of drug resistance,poly(ethylene glycol amine)(PEG)-modified alginate microparticles(ALG-PEG MPs)were developed then two different mechanisms were employed to load doxorubicin(Dox):1)forming Dox/ALGPEG complex by electrostatic attractions between unsaturated functional groups in Dox and ALG-PEG;2)forming Dox-ALG-PEG complex through EDC-reaction between the amino and carboxyl groups in Dox and ALG,***,tuftsin(TFT),a natural immunomodulation peptide,was conjugated to MPs in order to enhance the efficiency of cellular *** was found that the Dox-ALG-PEGTFT MPs exhibited a significantly slower release of Dox than Dox/ALG-PEG-TFT MPs in neutral medium,suggesting the role of covalent bonding in prolonging Dox ***,the release of Dox from these MPs was pH-sensitive,and the release rate was observably increased at pH 6.5 compared to the case at pH *** with Dox/ALG-PEG MPs and Dox-ALG-PEG MPs,their counterparts further conjugated with TFT more efficiently inhibited the growth of HeLa cells over a period of 48 h,implying the effectiveness of TFT in enhancing cellular uptake of *** a period of 48 h,Dox-ALG-PEG-TFT MPs inhibited the growth of HeLa cells less efficiently than Dox/ALG-PEG-TFT MPs but the difference was not significant(p>0.05).In consideration of the prolonged and sustained release of Dox,Dox-ALGPEG-TFT MPs possess the advantages for long-term treatment.

关键词： Controlled release Tuftsin Cellular uptake Chemotherapy

Heterogeneously elevated branched-chain/aromatic amino acids among new-onset type-2 diabetes mellitus patients are potentially skewed diabetes predictors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第1期15卷 53-71页

作者： Min Wang Yang Ou Xiang-Lian Yuan Xiu-Fang Zhu Ben Niu Zhuang Kang Bing Zhang anwar ahmed Guo-Qiang Xing Heng Su School of Chemical Science and Technology Yunnan UniversityKunming 650091Yunnan ProvinceChina Department of Endocrinology The First People’s Hospital of Yunnan ProvinceKunming 650032Yunnan ProvinceChina Clinical Laboratory Nanchong Central Hospital&The Second Clinical Medical College of North Sichuan Medical UniversityNanchong 637000Sichuan ProvinceChina Department of Preventive Medicine and Biostatistics Uniformed Services University of the Health SciencesBethesdaMD 20814United States The Affiliated Hospital and Second Clinical Medical College North Sichuan Medical UniversityNanchong 637000Sichuan ProvinceChina Department of Research and Development Lotus *** LLCGaithersburgMD 20878United States

BACKGROUND The lack of specific predictors for type-2 diabetes mellitus(T2DM)severely impacts early intervention/prevention *** branched-chain amino acids(BCAAs:Isoleucine,leucine,valine)and aromatic amino acids(AAAs:Tyrosine,tryptophan,phenylalanine)show high sensitivity and specificity in predicting diabetes in animals and predict T2DM 10-19 years before T2DM onset in clinical ***,improvement is needed to support its clinical *** To evaluate the effects of body mass index(BMI)and sex on BCAAs/AAAs in new-onset T2DM individuals with varying body *** Ninety-seven new-onset T2DM patients(<12 mo)differing in BMI[normal weight(NW),n=33,BMI=22.23±1.60;overweight,n=42,BMI=25.9±1.07;obesity(OB),n=22,BMI=31.23±2.31]from the First People’s Hospital of Yunnan Province,Kunming,China,were ***-way and 2-way ANOVAs were conducted to determine the effects of BMI and sex on BCAAs/*** Fasting serum AAAs,BCAAs,glutamate,and alanine were greater and high-density lipoprotein(HDL)was lower(P<0.05,each)in OB-T2DM patients than in NW-T2DM patients,especially in male OB-T2DM ***,histidine,leucine,methionine,and lysine were greater in male patients than in female ***,histidine,alanine,glutamate,lysine,valine,methionine,leucine,isoleucine,tyrosine,phenylalanine,and tryptophan were significantly correlated with abdominal adiposity,body weight and BMI,whereas isoleucine,leucine and phenylalanine were negatively correlated with *** Heterogeneously elevated amino acids,especially BCAAs/AAAs,across new-onset T2DM patients in differing BMI categories revealed a potentially skewed prediction of T2DM *** higher BCAA/AAA levels in obese T2DM patients would support T2DM prediction in obese individuals,whereas the lower levels of BCAAs/AAAs in NW-T2DM individuals may underestimate T2DM risk in NW *** potentially skewed T2DM prediction should be considered when BCAAs/AAAs are to

关键词： Hyperaminoacidemia Branched-chain/aromatic amino acids New-onset type-2 diabetes Predictor Obesity Sex

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

帕金森病患者失眠同其他非运动症状相关

帕金森病患者失眠同其他非运动症状相关

Visible light-driven photo remediation of hazardous cationic dye via Ce-doped WO_(3) nanostructures

中华医学会第十八次全国神经病学学术会议

作者：霍阳 Oluwadamilola Ojo James Bena Lu Wang Michelle Drerup Hubert H.Fernandez anwar ahmed Nancy Foldvary-Schaefer 北京大学人民医院神经内科美国克利夫兰医学中心

目的失眠是帕金森病患者的一个常见症状,但失眠与其他非运动症状,运动症状,功能和行为特点的关系尚未阐明。本文探讨失眠严重程度指数(ISI)和帕金森病病人其他特点之间的关系,本文也是帕金森病病人失眠治疗方法系列研究的一部分。方法...

目的失眠是帕金森病患者的一个常见症状,但失眠与其他非运动症状,运动症状,功能和行为特点的关系尚未阐明。本文探讨失眠严重程度指数(ISI)和帕金森病病人其他特点之间的关系,本文也是帕金森病病人失眠治疗方法系列研究的一部分。方法连续选取于运动障碍病门诊就诊的帕金森病人,完成ISI填写,收集相关指标:年龄,性别,帕金森病患病时间,标准左旋多巴每日剂量,是否应用脑深部电刺

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第5期42卷 869-878,I0003页

作者： Azra Haroon Kaseed anwar Arham S.ahmed Department of Physics Aligarh Muslim University202002AligarhIndia Interdisciplinary Nanotechnology Centre Aligarh Muslim University202002AligarhIndia

Ce-doped WO_(3) nanoparticles were successfully synthesized by the sol-gel method and characterized through advanced characterization *** high resolution transmission electron microscopy(HRTEM)and scanning electron microscopy(SEM)results show a reduction in the agglomeration of nanoparticles upon *** energy dispersive X-ray(EDX)analysis validates the existence of the Ce element in all the doped samples.X-ray photoelectron spectroscopy(XPS)and Raman spectra justify the presence of structural defects(oxygen vacancies)and successful formation of the monoclinic WO_(3) phase,*** Kubelka-Munk function indicates a decrease in band gap with doping,while photoluminescence(PL)spectra show intense visible and UV emissions,Significantly,all doped samples exhibit higher photocatalytic performance than pure WO_(3) nanoparticles,with the 6 wt%Ce-doped sample displaying the highest degradation *** with Ce can help to increase the surface area of WO_(3),thereby improving its photoactivity,Moreover,a correlation between PL and photocatalysis is established in the light of oxygen vacancies suggesting a direct dependence of high photocatalytic activity on strong PL signals of WO_(3) *** experiments further reveal that the degradation process is primarily driven by active species,providing insight into a plausible photocatalytic mechanism.

关键词： WO_(3) Rare-earth element Environmental crisis Oxygen vacancies Luminescence Photocatalysis

Characterization and anticancer potential of Withania somnifera fruit bioactives(a native species to Pakistan)using gas chromatography-mass spectrometer,nuclear magnetic resonance and liquid chromatography-mass spectrometry-electrospray ionization

在线全文

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medicine 2022年第6期42卷 908-914页

作者： Qudsia Tabassam Tahir Mehmood Sibtain ahmed Farooq anwar Abdul Rauf Raza Institute of Chemistry University of SargodhaSargodha-40100Pakistan Institute of Biochemistry and Biotechnology University of Veterinary and Animal Sciences-UVAS54000-Lahore.Pakistan University of California San Diego 9500 Gilman Drive La JollaCA 92093USA

INTRODUCTION:Withania somnifera(***)is a plant with remarkable pharmacological *** plant has an impressive profile of medicinal uses in the folk medicine system of several ***:This comprehensive study is aimed to characterize phytochemicals in fruit of *** and tested for in vitro anticancer potential to find out active candidate in disease prevention and ***:The bioactive components from *** fruit were extracted with polar and non-polar *** potential of the isolated bioactive was assessed against different cancer cell lines through MTT assay and Incucytes imaging *** extracts were characterized for secondary metabolites using GCMS(gas chromatography-mass spectrometer),LCMS(liquid(electrospray Ionization)and 1H-NMR(electrospray Ionization)***:Both freeze-dried and rotary evaporator condensed extracts exhibited anticancer potential against MDA-MB-231,MCF7-SKOV3 and SKBR3 cell *** tested extracts have cell growth inhibition potential against mammalian cancer cell *** acid purified from n-hexane extract through HPLC was investigated for its cytotoxicity against breast cancer cell line SKBR3 by using Incucytes imaging ***:We found that a variety of bioactive compounds existed in this *** identified compound that was not investigated for cytotoxicity in previous studies was purified and its application showed cytotoxicity on breast cancer cell lines.A number of bioactive identified from *** fruit may have an effective potential for development into chemotherapy drugs.

关键词： phytochemicals plants medicinal anti-cancer activities purification state-of-the-art techniques

Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第21期23卷 3864-3875页

作者： Moustafa Nouh Elemeery ahmed Noah Badr Marwa anwar Mohamed Doaa ahmed Ghareeb Medical Biotechnology Laboratory Genetic Engineering and Biotechnology Research DivisionNational Research Centre Toxicology and Food Contaminant Laboratory Food Science and Nutrition Research DivisionNational Research Centre Department of Chemical Pathology Medical Research InstituteAlexandria University Molecular Biology Laboratory Faculty of ScienceAlexandria University

AIM To investigate the prospective importance of serum micro(mi)RNAs(mi R-125 b, mi R-138 b, mi R-1269, mi R-214-5p, mi R-494, mi R375 and mi R-145) as early biomarkers for the diagnosis of hepatitis C virus(HCV)-related hepatocellular carcinoma(HCC).METHODS Two-hundred and fifty HCV4 a patients, 224 HCV4 aHCC patients, and 84 healthy controls were enrolled in the study. Expression levels of mi R214-5p, mi R-125 b, mi R-1269 and mi R-375 were quantified using quantitative real-time *** Expression of the selected mi RNAs in serum wassignificantly lower in HCC patients than in the healthy controls, except for mi R-1269 and mi R-494. There was a significant difference between HCC and HCV patients, in particular for HCC and late stage fibrosis, rather than HCV patients and early fibrosis. It is obvious that mi R-1269 was significantly upregulated in HCC cases compared to hepatic fibrosis cases. Each mi RNA can show HCC progression. Multivariate logistic regression analysis indicated that the tested panel of mi RNAs(mi R214-5p, mi R-125 b, mi R-1269 and mi R-375) represent accurate and specific indictors of HCC *** This study presents a panel of mi RNAs with strong power as putative diagnostic and prognostic biomarkers for HCV-induced HCC. Moreover, mi R-214-5p and mi R-1269 could be considered as early biomarkers for tracking the progress of liver fibrosis to HCC.

关键词： Micro RNA Hepatocellular carcinoma Fibrosis progression

UV RADIATION INDUCED GRAFT COPOLYMERIZATION OF ALLYL ACETATE ONTO POLY(ETHYLENE TEREPHTHALATE)(PET) FILMS FOR FUEL CELL MEMBRANES

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2012年第2期30卷 227-234页

作者： Mostak ahmed Mubarak A.Khan Nazia Rahman M.anwar H.Khan Radiation and Polymer Chemistry Laboratory Institute of Nuclear Science and TechnologyBangladesh Atomic Energy CommissionP.O.Box 3787DhakaBangladesh Department of Chemistry Shahjalal University of Science and TechnologySylhet-3114Bangladesh Department of Geography University of California BerkeleyBerkeleyCA 94720USA

Ultraviolet （UV）-induced graft copolymerization of allyl acetate （AA） monomer onto poly（ethylene terephthalate）（PET） films and the subsequent sulfonation on the monomer units in the grafting chain using chlorosulfonic acid （C1SO3H） were carried out to prepare proton exchange membranes （PEMs） for fuel cells. A maximum grafting value of 12.8% was found for 35 vol% allyl acetate after 3 h radiation time. Optimum concentration of C1SO3H was selected for the sulfonation reaction to be 0.05 mol/L based on the degree of sulfonation and the tensile strength studies of the membrane. The degree of sulfonation increased as the sulfonation reaction temperature and sulfonation time were increasing. The radiation grafting and the sulfonation have been confirmed by titrimetric and gravimetric analyses as well as FTIR spectroscopy. The maximum ion exchange capacity （IEC） of 0.04125 mmol g-1 was found at 12.1% degree of sulfonation and the maximum proton conductivity was found to be 0.035 S cm-1 at 30℃ and a relative humidity of 60%. The various physical and chemical properties of the PEMs such as water uptake, mechanical strength, thermal durability and oxidative stability were also studied. To investigate the suitability of the prepared membrane for fuel cell applications, its properties were compared with those ofNafion 117.

关键词： Polymer electrolyte membrane Allyl acetate Fuel cell UV radiation Grafting Sulfonation.

SUSTAINABILITY ASSESSMENT OF REINFORCED CONCRETE BEAM MIXES CONTAINING RECYCLED AGGREGATES AND INDUSTRIAL BY-PRODUCTS

在线全文

学校读者我要写书评

暂无评论

Journal of Green Building 2020年第3期15卷 95-119页

作者： Faiz Uddin ahmed Shaikh anwar Hosan Wahidul K.Biswas School of Civil and Mechanical Engineering Curtin UniversityPerthAustralia

A vast amount of construction and demolition(C&D)wastes are generated in Western Australia(WA)of which a major portion goes to *** diversion of C&D waste from landfills would be the single most significant opportunity for WA to improve its recovery performance.C&D waste materials have already been investigated for their appropriateness and use in pavement and *** work is the continuation of the authors’previous work involving further experimental tests to prove the structural suitability of a building’s structural member(i.e.,beam)made of recycled aggregates and industrial *** concrete mixes considered in this study are 100NA+100 OPC(Control),100RA+100OPC,50RA+50NA+90OPC+10SF and 50RA+50NA+60OPC+30FA+*** Reinforced Concrete(RC)beam made of 50RA+50NA+60OPC+30FA+10SF concrete mix was found to be the only eco-efficient *** option has reduced the level of environmental impacts in a cost-competitive *** use of this eco-efficient option could also provide new employment opportunities and significant improvements in terms of land and energy resources conservation and bio-diversity enhancement.

关键词： OPC=ordinary Portland cement NA=Natural Aggregate RA=Recycled Aggregates SF=Silica Fumes FA=Fly Ash