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Prevalence and associated factors of hospitalization for dysglycemia among elderly type 2 diabetes patients: A nationwide study

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World Journal of Diabetes 2019年第3期10卷 212-223页

作者： Wisit Kaewput Charat Thongprayoon Narittaya Varothai anupong sirirungreung Ram Rangsin Tarun Bathini Michael A Mao Wisit Cheungpasitporn Department of Military and Community Medicine Phramongkutklao College of Medicine Bangkok 10400 Thailand Division of Nephrology and Hypertension Department of Medicine Mayo Clinic Rochester MN 55905 United States Division of Geriatrics Department of Medicine Phramongkutklao Hospital and College of Medicine Bangkok 10400 Thailand Department of Epidemiology Fielding School of Public Health University of California Los Angeles CA 90095 United States Department of Internal Medicine University of Arizona Tucson AZ 85721 United States Division of Nephrology Department of Medicine University of Mississippi Medical Center Jackson MS 39216 United States

BACKGROUND The prevalence of older individuals with type 2 diabetes mellitus (T2DM) is increasing due to the aging population and improved medical care. These patients are very susceptible to disease and treatment-related hospitalizations, resulting in higher health care costs, morbidity, and decreased quality of life. However, data of treatment-related complications, especially dysglycemiarelated hospitalizations, are lacking. AIM To assess the prevalence and associated factors for dysglycemia-related hospitalizations among elderly diabetic patients in Thailand using nationwide patient sample. METHODS T2DM patients aged ≥ 65 years who received medical care at public hospitals in Thailand in the year 2014 were included. The prevalence of hospitalization due to dysglycemia within one year was examined. Multivariable logistic regression was performed to assess the independent factors associated with hospitalization due to hypoglycemia and hyperglycemia RESULTS A total of 11404 elderly T2DM patients were enrolled in this study. The mean age was 72.9 ± 5.5 years. The prevalence of hospital admissions due to diabetic ketoacidosis, hyperosmolar hyperglycemic state, hyperglycemic dehydration syndrome, and hypoglycemia among elderly T2DM patients in the year 2014 was 0.1%, 0.1%, 1.7% and 3.1%, respectively. Increased hospitalization due to hypoglycemia was associated with older age, female sex, had hypertension, dementia, lower body mass index, elevated hemoglobin A1C (HbA1C), decreased kidney function, insulin use. Increased hospitalization due to hyperglycemia was associated with dementia, depression, lower body mass index, elevated HbA1C, and insulin use. CONCLUSION The prevalence of dysglycemia-related hospitalization in elderly T2DM patients in Thailand was 4.9%. Close monitoring of blood glucose should be provided in high-risk patients for prevention and early detection for these complications.

关键词： Type 2 diabetes mellitus Hospitalization Diabetes in elderly Dysglycemia Hypoglycemia Hyperglycemia

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